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2022 Vol. 19, No. 6 Published: 2022-02-25

	6	Analysis on the medication rule and mechanism of Li Enfu in the treatment of chronic atrophic gastritis based on data mining and network pharmacology#br#
		ZHENG Leilei1 SHA Ying1 LI Huan1 DING Hui2
		Objective To analyze the medication rule and mechanism of Li Enfu in the treatment of chronic atrophic gastritis based on data mining. Methods After organizing the prescriptions used in the book One hundred cases of atrophic gastritis cure——Professor Li Enfu’s medical cases and medical treatises, inputed into the traditional Chinese medicine inheritance assistance platform, the association rules were analyzed, and the key drugs were studied by network pharmacology. Results The high-frequency drugs, four nature, five flavors, and channel distribution were obtained, the results of core drugs and combinations, new prescriptions, gene ontology, and Kyoto Gene and Genome Database enrichment analyses were presented. Finally, the medicine-component-target maps were constructed. Conclusion Radix Angelicae Sinensis, Radix Paeoniae Alba, and Rhizoma Ligustici Chuanxiong can act on chronic atrophic gastritis, which can provide reference for clinical use and development of new drug.
		2022 Vol. 19 (6): 6-10 [Abstract] ( 206 ) HTML (1 KB) PDF (1847 KB) ( 193 )

	11	Research atlas analysis of acupuncture and moxibustion treatment for essential hypertension in the past 20 years based on CiteSpace#br# #br#
		NIU Ziqing1 ZHENG Xuan2 LIU Xiaojuan1 TAN Yan1 CAO Yue1 FANG Chuang1 BAO Chengtong1 ZHANG Wei1
		Objective To visually analyze the related literature on acupuncture and moxibustion treatment of essential hypertension (EH) in the past 20 years, and to get the research hotspots and research trends in this field. Methods CiteSpace software was used to analyze the authors, institutions, keywords, and research hotspots of literatures related to acupuncture and moxibustion treatment for EH in Chinese National Knowledge Infrastructure from January 2001 to June 2021, and the atlas was drew. Results A total of 773 literatures were included, and 504 authors were included to form three influential research teams: Wang Shu, Shi Xuemin and Liang Fanrong. With First Teaching Hospital of Tianjin University of Traditional Chinese Medicine as the core, research institutions in Tianjin have formed a research advantage network. Keywords co-occurrence results showed that the top five keywords were essential hypertension, acupuncture, hypertension, hypertension, and acupuncture therapy. Keywords co-occurrence network centrality of the top 16 keywords could be divided into four categories: disease, treatment, acupoint, mechanism research. The hot highlight word results showed that the research hotspots could be roughly divided into the following categories: the research hotspots of acupoints included féngchí point, rényíng point, and qūchí point; the hot spots of therapeutic research included acupuncture and moxibustion therapy; the basic research hotspots of mechanism included gene chip, hypothalamus, nitric oxide; hot spots of clinical efficacy evaluation included immediate hypotension, heart rate variation rate, circadian rhythm of blood pressure. Conclusion In recent 20 years, the domestic research on acupuncture and moxibustion treatment for EH has formed a regional advantage network based on Tianjin area and formed a number of influential research teams. And the efficacy evaluation tends to be diversified, but there is a problem of weak basic research.
		2022 Vol. 19 (6): 11-15 [Abstract] ( 206 ) HTML (1 KB) PDF (1671 KB) ( 180 )

	16	Bioinformatics analysis of endometrial cancer based on TCGA and Oncomine database#br#
		DUAN Hongtao PAN Yong
		Objective To conduct a bioinformatics analysis of endometrial cancer through TCGA and Oncomine databases, and to deeply explore the key genes of endometrial cancer. Methods Endometrial cancer transcriptome data were download from the TCGA database, differentially expressed genes were obtained with R software to compare endometrial cancer and normal paracancer tissues and functional enrichment analysis of differentially expressed genes were performde with online bioinformatics tools, and a protein-protein interaction (PPI) network was constructed, and Cytoscape software was screened the PPI network to obtain the Hub gene. Further meta-analysis was performed on the Oncomine database to obtain key genes. Results A total of 1897 differentially expressed genes in endometrial cancer were excavated, of which 1085 were up-regulated and 812 were down-regulated. The functional enrichment analysis was performed on them. The PPI network was constructed using online bioinformatics tools. The top ten Hub genes were CDC20, CCNB1, BUB1, CCNB2, DLGAP5, TPX2, NCAPG, NCAPH, CENPF, and CDCA8. The Hub gene was meta-analyzed through the Oncomine database, and the five key genes were finally obtained BUB1, TPX2, NCAPH, CENPF, and CDCA8. Conclusion Based on the TCGA and Oncomine databases, obtaining key genes for endometrial cancer provide new ideas for the diagnosis, treatment and prognosis of endometrial cancer.
		2022 Vol. 19 (6): 16-20 [Abstract] ( 84 ) HTML (1 KB) PDF (2346 KB) ( 52 )

	21	Effect of osteopontin on proliferation, invasion and migration of gastric cancer cells#br#
		QIN Yuechao1 YUAN Xiaolin2 QU Fanjie1
		Objective To investigate the effect of osteopontin (OPN) on the proliferation, invasion, and migration ability of gastric cancer SGC-7901 cells. Methods Gastric cancer SGC-7901 cells were cultured in vitro and they were divided into three groups: control group, NC-shRNA group, OPN-shRNA group. The proliferation of cell was detected by MTT assay, and the invasion and migration were detected by Transwell assay. The expression of cyclin D1, vascular endothelial growth factor (VEGF), and matrix metallo proteinase 2 (MMP-2) was detected by Western blot assay. Results There was no significant difference between control group and NC-shRNA group in cell proliferation, invasion, migration, and protein expression levels (P > 0.05). After silencing OPN gene expression, OPN-shRNA had significant cell proliferation, invasion, and migration capabilities were lower than control group, the differences were highly statistically significant (P < 0.01); the expression levels of OPN-shRNA cyclin D1, VEGF, and MMP-2 protein were lower than control group, and the difference was statistically significant (P < 0.05). Conclusion OPN can enhance the proliferation, invasion, and migration of gastric cancer SGC-7901 cells, and its mechanism may be related to the regulation of cyclin D1, VEGF, and MMP-2 expression.
		2022 Vol. 19 (6): 21-24 [Abstract] ( 209 ) HTML (1 KB) PDF (1117 KB) ( 51 )

	25	Consistency evaluation of magnetic particle chemiluminescence assay and electrochemiluminescence assay for the detection of thyroid-stimulating hormone receptor antibodies#br#
		SUI Xin1 XIE Peng2 HUANG Jianmin2 GAO Jianqing2 JING Jianmin2 WEI Lingge2▲ WU Weijie2 YU Hongwei2
		Objective To study the difference between the content of serum thyrotropin receptor antibody (TRAb) detected by magnetic particle chemical luminescence assay (CLIA) and electrochemical luminescence assay (ECLIA), to explore the feasibility and practicality of CLIA to detect TRAb. Methods A total of 118 serum samples were collected from the outpatient and inpatient departments of the Endocrinology Department of the Third Hospital of Hebei Medical University from November to December 2020. Serum samples were detected simultaneously by two methods. Among them, there were 70 cases of thyroid-related diseases, and 48 people with physical examination and non-thyroid diseases. The correlation, deviation analysis, negative-positive coincidence rate of the two detection methods were compared, and the precision, linear range and reference interval of CLIA method for detecting TRAb were verified. Results The overall correlation between CLIA and ECLIA in detecting TRAb was good (r = 0.969); Bland-Altman deviation analysis showed that the results of the two methods for detecting TRAb were in good agreement at low concentrations (0-5 IU/L), but with the increase of TRAb concentration, the deviation gradually increased; the positive coincidence rate, negative coincidence rate and total coincidence rate of the two were 86.84%, 100%, and 95.76%, respectively, and the Kappa value was 0.8995 (P ＜ 0.01). The intra-assay CVs of low and high TRAb values detected by CLIA were 2.68% and 0.92%, respectively, and the inter-assay CVs were 5.70% and 1.48%, respectively; the linearity was good between 0.25 and 40 IU/L, and R2 = 0.9987. Conclusion In this study, it is believe that CLIA and ECLIA have good consistency, and CLIA can be used as a reliable method for clinical detection of serum TRAb levels.
		2022 Vol. 19 (6): 25-28 [Abstract] ( 90 ) HTML (1 KB) PDF (781 KB) ( 53 )

	29	Analysis of Professor Zhao Haibin’s formulation rules and medication experience in the treatment of psycho-cardiological disease based on data mining#br#
		LIU Xiang1 TANG Zhuoran1 QI Xin1 JIA Zihao1 ZHOU Yue1 ZHAO Haibin2
		Objective To analyze the rule of Professor Zhao Haibin’s formulation rules and experience in the treatment of psycho-cardiological disease based on data mining technology. Methods A total of 194 prescriptions for psycho-cardiological disease treated by Professor Zhao Haibin from January 2018 to April 2021 were recorded into the system of traditional Chinese medcine assisting inheritation platform (V2.5), and association rules and hierarchical clustering algorithms were adopted. Data mining was carried out from many aspects, such as drug frequency, four nature of drugs and five flavors, and their return meridian, core combination and potential new prescription. Results The 194 prescriptions contain 148 traditional Chinese medicine ingredients, warm, cold, and clam drugs were more common, while pungent, bitter, and sweet drugs were commonly used. The main channels were spleen, lung, stomach, liver, and heart. The top three Chinese medicines were Rhizoma Pinelliae, Poria, and Ramulus Cinnamomi. A total of 22 drug pairs combinations were obtained, and the correlation between Rhizoma Atractylodis Macrocephalae and Poria was the highest. Twenty-two core combinations composed of three drugs and four new formula combinations were excavated. Conclusion In the treatment of psycho-cardiological disease, Professor Zhao Haibin attaches great importance to regulating qi movement, and often uses the methods of regulating qi-flowing and heat-clearing, dissipating phlegm and inducing diuresis, supplementing qi and blood, promoting blood circulation for removing obstruction in collaterals, resolving phlegm and benefiting water, tonifying qi and blood, and tranquillization.
		2022 Vol. 19 (6): 29-33 [Abstract] ( 157 ) HTML (1 KB) PDF (1237 KB) ( 55 )

	34	Clinical research progress of heart failure with mid-range ejection fraction#br#
		SAI Yaoqing LU Shengyu CAO Bangming
		Heart failure (HF) is the terminal stage of heart disease, with high incidence and poor prognosis. In 2016, European Society of Cardiology defined HF with the left ventricular ejection fraction (LVEF) of 40%-49% as the heart failure with mid-range ejection fraction (HFmrEF). This article summarizes the clinical research on HFmrEF finding that ischemic heart disease is one of the most important factors of HFmrEF, combines with atrial fibrillation and hypertension and other diseases, it emphasizes that personalized treatment strategies based on etiology and complications could bring more benefits to patients suffering from HFmrEF. In terms of treatment, traditional drugs, including renin-angiotensin-aldosterone system antagonists, β-receptor blockers, and aldosterone receptor antagonists still have positive effects on HFmrEF; the emerging drug angiotensinreceptor neprilysin enzyme inhibitor has become a recommendation treatment for HFmrEF; some patients with HFmrEF can benefit from Vericiguat and ferric carboxymaltose; sodium-glucose cotransporter 2 inhibitors, and Omecamtiv mecarbil have potential for the treatment of HFmrEF, and they can be used as important research directions in the future. In addition, the changes of LVEF have suggestive effects on the prognosis of HFmrEF.
		2022 Vol. 19 (6): 34-38 [Abstract] ( 131 ) HTML (1 KB) PDF (405 KB) ( 114 )

	39	Methods for the detection of circulating tumor cells #br#
		SONG Yuhang1 YANG Xiaolin2 LIU Kang1 SONG Guiqin2
		Circulating tumor cells (CTCs) carry important information about tumor genesis, development, and metastasis and are closely associated with tumor metastasis. In order to understand the function and molecular characteristics of CTCs and develop effective surveillance and treatment strategies for cancer, the development of CTCs enrichment and identification technology is a key step. In recent years, great progress has been made in the detection of CTCs in vitro, at the same time, real-time, non-invasive in vivo detection technology has gradually emerged in the market. This paper summarizes the methods of CTCs detection in vitro and in vivo, and puts forward the challenges and strategies of CTCs detection.
		2022 Vol. 19 (6): 39-42 [Abstract] ( 116 ) HTML (1 KB) PDF (554 KB) ( 71 )

	43	Investigation on sub-health status of night shift nurses and analysis of risk factors#br#
		ZHANG Xingxing1 CAI Wenwen2 XIN Hongjie3 YANG Qiuyu3 HE Xuanyu3 BAI Yang3 RUAN Weiqing1▲
		Objective To investigate the current status of sub-health status of night shift nurses and to analyze risk factors. Methods From November 2020 to May 2021, convenience sampling was adopted, and a total of 440 night shift nurses in Nanfang Hospital of Southern Medical University were selected as the research objects. The general information questionnaire and sub-health measurement scale were used to conduct a cross-sectional survey. Results A total of 440 questionnaires were distributed, 425 valid questionnaires were recovered, and the effective recovery rate was 96.6%. The sub-health incidence rate of 425 night shift nurses was 77.6%, and the total sub-health score was (52.06±10.28) points, with the lowest scores in the three dimensions of psychological symptoms, organ function, and physical symptoms. Univariate analysis showed that compared the sub-health status of the night shift nurses, the differences of age, working years, education, marital status, monthly night shift frequency, weekly exercise frequency, weekly meal frequency, daily average sleep time were statistically significant (P ＜ 0.05). Multivariate logistic regression analysis showed that weekly exercise 1-3 times/week (OR = 4.521, 95%CI: 1.185-17.252), weekly exercise ＞3-5 times/week (OR = 4.548, 95%CI: 1.690-12.240), no regular meals per week (OR = 7.020, 95%CI: 1.693-29.111), regular meals on 1 to 3 days per week (OR = 4.833, 95%CI: 2.230-10.694), average daily sleep ＞6-7 h (OR = 4.337, 95%CI: 1.845-10.193), 1-3 d per month of night shift(OR = 7.836, 95%CI: 2.733-22.465), ＞3-7d per month of night shift (OR = 2.119, 95%CI: 1.051-4.271) were risk factors for sub-health status of night shift nurses (P ＜ 0.05). Conclusion The incidence of sub-health in night shift nurses is high, and it is affected by many factors. Both managers and nurses should improve their awareness of health management, improve their sub-health status in a timely manner, and improve the health level of nurses.
		2022 Vol. 19 (6): 43-47 [Abstract] ( 141 ) HTML (1 KB) PDF (653 KB) ( 169 )

	48	Discharge readiness and its influencing factors of patients after first-stage sacral neuromodulation#br#
		ZHAO Yao1 DING Qingqing1 WANG Shuangfeng1 DING Ziyu1 LI Jiajia1 LIU Huifan2▲
		Objective To investigate the readiness for hospital discharge and its influencing factors in patients after first-stage sacral neuromodulation (SNM). Methods From July 2019 to June 2021, a convenience sampling method was used to select 106 patients with SNM after first-stage surgery in the Department of Urology, the First Affiliated Hospital of Zhengzhou University as the research subjects. The general information questionnaire, hospital discharge readiness scale, discharge guidance quality scale and social support scale were used to investigate them. Results A total of 106 questionnaires were distributed in this survey, and 103 valid questionnaires were recovered, with an effective recovery rate of 97.17%. The total score of the patient’s discharge readiness was (89.39±6.78) points, which was at a moderate level. The results of univariate analysis showed that there were significant differences in the scores of hospital discharge readiness among patients with different educational levels, places of residence, income, economic burden, perceived disease severity and disease types (P ＜ 0.05). Pearson correlation analysis showed that the discharge readiness of patients after the first-stage SNM was positively correlated with the quality of discharge guidance and the total score of social support (r = 0.506, 0.602, P ＜ 0.05). Multiple linear regression analysis showed that education level, income, economic burden, perceived disease severity, quality of discharge guidances, and social support were the main influencing factors for discharge readiness (P ＜ 0.05). Conclusion Patients after the first stage of SNM have not been fully prepared for discharge, and medical staff should give targeted interventions according to their specific conditions.
		2022 Vol. 19 (6): 48-51,75 [Abstract] ( 88 ) HTML (1 KB) PDF (690 KB) ( 23 )

	52	Analysis of the prevalence and influencing factors of osteopenia among the elderly in the community#br#
		ZHANG Ruixin XIE Hui CAI Weiwei LI Yanling LI Qiyu
		Objective To analyze the prevalence and related influencing factors of osteopenia in the community elderly in Bengbu City. Methods A total of 1076 elderly people who underwent physical examinations in Dongfeng and Yan’an communities in Bengbu City from February 2019 to February 2021 were selected as the research subjects, the general information of the patients was collected, and relevant physical examinations were carried out. According to the T-value of calcaneal bone mineral density measured by ultrasound absorptiometry, the subjects were divided into three groups: 474 people with normal bone mass, 515 cases with osteopenia, and 87 cases with osteoporosis. Logistic regression was used to analyze the influencing factors of osteopenia in the elderly in the community. Results There were 515 elderly people with osteopenia in the community, including 194 males and 321 females, aged (69.58±6.01) years old. The detection rate of osteopenia was 47.86%. Univariate analysis showed that gender, age, smoking, physical activity, cardiovascular disease, diabetes, body weight, body water, inorganic salt, muscle mass, ankle-brachial index, diastolic blood pressure, and growth index were significantly different (P ＜ 0.05). Logistic regression analysis showed that gender (OR = 2.300), body weight (OR = 0.976), ankle-brachial index (OR = 0.255), inorganic salts (OR = 1.117), cardiovascular disease (OR = 1.448), diabetes (OR = 0.722) and physical activity (OR = 0.824) were the main influencing factors for osteopenia (P ＜ 0.05). Conclusion Elderly people in the community should pay attention to their chronic diseases, avoid low body weight, increase physical activity, and prevent and delay the occurrence of osteopenia.
		2022 Vol. 19 (6): 52-55,84 [Abstract] ( 223 ) HTML (1 KB) PDF (709 KB) ( 53 )

	56	Correlation analysis between professional commitment and organizational support among doctors in tertiary hospitals in China#br#
		OU Ping1 LIU Zengjing2 WEI Haini1 WU Cuili1 WEI Liufang1▲
		Objective To understand the impact of demographic variables on doctors’ organizational support and professional commitment in tertiary hospitals across China, and to provide suggestions for improving doctors’ professional commitment. Methods A total of 2500 clinicians from tertiary hospitals at a conference in 2017 were selected as the research objects, demographic data, professional commitment, and sense of organizational support were collected, and their correlations were analyzed. Results In this study, 1974 questionnaires were recovered, and 1800 were valid questionnaires, with an effective recovery rate of 91.23%. There were highly statistically significant differences in organizational support and career commitment among different regions, professional titles, working years, and age groups (P ＜ 0.01). There was a highly statistically significant difference in the sense of organizational support among doctors in different departments (P ＜ 0.01). There was a positive correlation between organizational support and career commitment (r = 0.54, P ＜ 0.01). The sense of organizational support was positively correlated with professional title, educational background and years of experience (r = 0.11, 0.06, 0.12, P ＜ 0.01), but was negatively correlated with region (r = -0.08, P ＜ 0.05). In addition, career commitment was positively correlated with age, professional title, and working years (r = 0.16, 0.15, 0.17, P ＜ 0.01). Conclusion Managers should attach importance to doctors’ sense of organizational support and professional commitment, increase policy support, improve the corresponding management system, and then enhance doctors’ professional commitment.
		2022 Vol. 19 (6): 56-59,92 [Abstract] ( 59 ) HTML (1 KB) PDF (650 KB) ( 45 )

	60	Analysis of children’s tuberculosis in our hospital and the influencing factors of severe tuberculosis#br#
		XIAO Litao1 XU Minghao2 WANG Yanchun1 ZHUN Tingyan1 LI Quanhong3 YANG Xiaotao1
		Objective To explore the situation of children’s tuberculosis in Kunming Children’s Hospital (hereinafter referred to as “our hospital”) and the influencing factors of severe tuberculosis in order to propose targeted preventive measures to reduce the incidence of the disease. Methods The clinical data of 312 children with tuberculosis admitted to our hospital from January 2016 to December 2020 were collected, and the clinical characteristics of children’s tuberculosis, according to the severity of the disease, they were divided into severe tuberculosis group (87 cases) and non-severe tuberculosis group (225 cases), the influencing factors of severe tuberculosis were analyzed. Results From 2016 to 2020, the number of inpatients with childhood tuberculosis in our hospital has decreased year by year; the clinical manifestations of childhood tuberculosis were mainly fever and cough; the incidence of Tuberculosis in males was more common than that in females, and the incidence was most common in patients aged seven and over, followed by the age group of three to seven years. The incidence of tuberculosis was high in areas with relatively backward economy, serious environmental pollution, dense population and high mobility. The incidence of severe tuberculosis in children was related to age, living environment, tuberculosis contact history, bacille calmette-guerin vaccination history, and nutritional status (P ＜ 0.05). Logistic regression analysis showed that age (OR = 1.918, 95%CI: 1.319-2.642, P = 0.008), living environment (OR = 1.147, 95%CI: 1.096-1.253, P = 0.001), nutritional status (OR = 2.061, 95%CI: 1.437-2.712, P = 0.042), history of tuberculosis exposure (OR = 2.168, 95%CI: 1.413-2.897, P = 0.017) were associated risk factors for severe tuberculosis in children, and bacille calmette-guerin vaccination was a protective factor (OR = 0.887, 95%CI: 0.268-0.953, P = 0.007). Conclusion We should focus on the clinical characteristics of childhood tuberculosis and the high-risk factors that lead to severe tuberculosis, raise awareness, pay close attention to those with high-risk factors, and actively prevent and control tuberculosis, especially severe tuberculosis in children.
		2022 Vol. 19 (6): 60-63 [Abstract] ( 149 ) HTML (1 KB) PDF (591 KB) ( 135 )

	64	Analysis of influencing factors of alexithymia in patients with breast cancer after modified radical surgery#br#
		QIAN Jia1 WU Lixin2
		Objective To observe the influencing factors of alexithymia in patients with breast cancer after modified radical surgery. Methods A total of 100 patients with breast cancer undergoing modified radical mastectomy in Anqing Hospital Affiliated to Anhui Medical University from April 2017 to April 2021 were selected as the research subjects. The alexithymia degree of patients were assessed with 20-item Toronto alexithymia scale (TAS-20) after operation, the baseline data questionnaire of patients was designed, the TAS-20 scores of patients with different data characteristics were compared. The influencing factors of alexithymia in patients with breast cancer after modified radical surgery. Results The average TAS-20 score of 100 patients with breast cancer after modified radical mastectomy was (62.65±7.13) points. TAS-20 score of patients with high school education and below was higher than that of patients with college education and above, and the difference was statistically significant (P ＜ 0.05). Correlation analysis showed that TAS-20 score was negatively correlated with brief-illness perception questionnaire (B-IPQ), psychological resilience scale-14 (RS-14), and perceived social support scale (PSSS) scores (r ＜ 0, P < 0.05). Multivariate analysis showed that B-IPQ (X1), RS-14 (X2), and PSSS score (X3) were the influencing factors of alexithymia after modified radical mastectomy (P ＜ 0.05). Multiple linear regression equation was Y = 7.955-0.297X1-0.460X2-0.528X3 (F = 152.124, R2 = 0.865, adjusted R2 = 0.859, P ＜ 0.05). Conclusion The degree of alexithymia in breast cancer patients after modified radical mastectomy is more serious, which may be affected by patients’ disease cognition, mental resilience and understanding of social support.
		2022 Vol. 19 (6): 64-67 [Abstract] ( 159 ) HTML (1 KB) PDF (528 KB) ( 63 )

	68	Related factors of readiness for hospital discharge after internal fixation of complex tibial plateau fractures#br#
		CAI Rui HU Yanhua
		Objective To explore the related factors of readiness for hospital discharge after internal fixation of complex tibial plateau fracture (CTPF). Methods A total of 100 patients with CTPF treated in the First Affiliated Hospital of Xinjiang Medical University from January 2018 to December 2020 were selected, all patients were treated with internal fixation, the readiness for hospital discharge scale (RHDS) was used to evaluate the postoperative readiness for hospital discharge. The data of all patients was collected, the RHDS scores of CTPF patients with different data characteristics after internal fixation were compared, the factors that might affect the readiness for hospital discharge of CTPF patients were analyzed. Results The mean RHDS score of 100 CTPF patients after internal fixation was (69.48±7.82) points. The RHDS scores of CTPF patients with college education or above, mild to moderate pain, normal post-traumatic growth level, and mild to moderate dependence were higher than those of CTPF patients with high school or technical secondary school or below, severe pain, low post-traumatic growth level, and severe dependence after internal fixation, the differences were statistically significant (P ＜ 0.05). The results of multiple linear regression analysis showed that education level (X1), pain level (X2), post-traumatic growth level (X3), and dependence level (X4) might be the influencing factors for the discharge readiness of CTPF patients after internal fixation (P ＜ 0.05). The equation was as follows: Y = 58.446+11.804X1-10.750X2+18.464X3+15.740X4 (F = 350.183, R2 = 0.936, adjusted R2 = 0.934, P ＜ 0.05). Conclusion The degree of education, pain, post-traumatic growth, and dependence may affect the discharge readiness of CTPF patients after internal fixation.
		2022 Vol. 19 (6): 68-71 [Abstract] ( 127 ) HTML (1 KB) PDF (492 KB) ( 24 )

	72	Analysis on influencing factors of psychological resilience level in patients with cervical cancer#br#
		JIANG Juqin LIU Yun WANG Yuan LIU Meiling ZHA Yaqi
		Objective To explore the psychological resilience level and its influencing factors in patients with cervical cancer. Methods A total of 114 patients with cervical cancer admitted to Anqing Municipal Hospital of Anhui Province from July 2017 to December 2020 were selected. The general mental resilience scale (CD-RISC) was used to evaluate their mental resilience before discharge. The baseline data questionnaire was designed to inquire and filled in the patient data and compared the mental resilience levels of patients with different baseline data, multiple linear regression was used to analyzed the influencing factors of psychological resilience. Results A total of 114 copies of CD-RISC, baseline data questionnaire, Huaxi emotional index (HEI), and perceived social support scale (PSSS) were issued in this study, and all of them were recovered with a effective recovery rate of 100%. The CD-RISC score of 114 patients with cervical cancer was (54.18±7.80) points. There were statistically significant differences in CD-RISC scores among patients with different education levels, residence, HEI, and PSSS scores (P ＜ 0.05). The results of multi-factor analysis showed that education level (X1), residence (X2), HEI (X3), and PSSS score (X4) were all influential factors of CD-RISC score (P < 0.05), and multiple linear regression equation was obtained: Y = 62.247-4.548X1-2.816X2-3.192X3-4.096X4 (F = 7.774, R2 = 0.222, adjusted R2 = 0.193, P ＜ 0.05). Conclusion The influencing factors of mental resilience in patients with cervical cancer may include education level, residence, HEI, and PSSS score. Based on this, targeted intervention measures can be implemented to improve the psychological resilience of patients and promote their recovery.
		2022 Vol. 19 (6): 72-75 [Abstract] ( 138 ) HTML (1 KB) PDF (559 KB) ( 107 )

	76	Effiect of Enpagliflozin combined with Metformin in the treatment of type 2 diabetes mellitus#br#
		NIU Shangmei1 SONG Xiaomeng1 ZHANG Xiaojie1 YANG Yingtao2 GUO Huijun2 HAN Shichao1
		Objective To explore the effect of Empagliflozin combined with Metformin on patients with type 2 diabetes mellitus (T2DM). Methods A total of 200 T2DM patients admitted to the Department of Endocrinology of the Handan First Hospital, Hebei Province from November 2018 to February 2020, and they were divided into control group and observation group according to the random number table method, with 100 cases in each group. Among them, the control group was given Metformin, and the observation group was given Enggliazin combined with Metformin, and the treatment course was 12 months. After treatment, glucose metabolism indexes, cardiac ultrasound detection indexes, body weight, mean arterial pressure, sodium ion, and serum uric acid levels were compared between the two groups, and the occurrence of adverse reactions during treatment was recorded. Results After treatment, the levels of fasting blood glucose, 2 hours postprandial blood glucose, and glycosylated hemoglobin in two groups were lower than before, and the observation group was lower than the control group (P ＜ 0.05). After treatment, the E peak, LVEF, and LV mass index in the two groups were decreased, but the observation group was better than those of the control group (P ＜ 0.05). After treatment, body weight, mean arterial pressure, sodium ion, and serum uric acid levels in two groups were lower than before, and observation group was lower than those of control group (P ＜ 0.05). There was no significant difference in the total incidence of adverse reactions between the two groups after treatment (P ＞ 0.05). Conclusion Enpagliflozin combined with Metformin in the treatment of T2DM can improve the patient’s blood glucose control, and by regulating the patient’s blood sugar, reducing the patient’s body weight, serum uric acid, maintaining blood pressure, and sodiumion levels, and protecting the cardiovascular system of T2DM patients.
		2022 Vol. 19 (6): 76-80 [Abstract] ( 152 ) HTML (1 KB) PDF (633 KB) ( 29 )

	81	Effect of Doxazosin combined with Drotaverine Hydrochloride in the treatment of lower ureteral calculi#br#
		HU Yuan LI Bin
		Objective To evaluate the efficacy and safety of Doxazosin combined with Drotaverine Hydrochloride in the treatment of lower ureteral calculi. Methods A total of 400 patients with lower ureteral calculi treated in the First People’s Hospital of Foshan, Guangdong Province from January 2017 to January 2020 were selected as study objects. They were divided into group A, B, C, and group D, according to treatment plans, with 100 patients in each group. All patients in four groups were routinely treated with Niaoshitong Pills; group A did not add any ureteral smooth muscle relaxant; group B was given Doxazosin, group C was given Trotaverine Hydrochloride, and group D was given Doxazosin combined and Drotaverine Hydrochloride. All patients were followed up for four weeks, and the stone excretion rate, stone excretion time, renal colic recurrence rate and the incidence of adverse reactions were compared among four groups. Results There were statistically significant differences in stone excretion rate, stone excretion time, and renal colic recurrence rate among four groups (P < 0.008). The stone excretion rate of group D was higher than that of group A and C, and renal colic recurrence rate was lower than that of group A and C; the stone excretion rate of group B was higher than that of group A, and renal colic recurrence rate was lower than that of group A, and the differences were statistically significant (P < 0.05). Pairwise comparison of stone excretion time among four groups showed statistical significance (P < 0.05). There were no significant differences in the incidence of adverse reactions among four groups (P > 0.05). Conclusion Doxazosin combined with Drotaverine Hydrochloride in the treatment of lower ureteral calculi has good efficacy and high safety, which is worthy of clinical application.
		2022 Vol. 19 (6): 81-84 [Abstract] ( 63 ) HTML (1 KB) PDF (566 KB) ( 124 )

	85	Clinical study of Pie-crusting technique in treatment of varus deformity of knee osteoarthritis during total knee replacement#br#
		DONG Yuefu1 SONG Qunshan2 XU Xiangjun1 WANG Guodong2 LI Bingyan1 MOU Zhifang3▲
		Objective To investigate the clinical effect of Pie-crusting technique in treatment of varus deformity of knee osteoarthritis in total knee replacement. Methods A total of 82 patients with knee osteoarthritis varus deformity treated in Lianyungang Hospital Affiliated to Xuzhou Medical University of Jiangsu Province from January 2018 to January 2021 were randomly divided into study group and control group according to random number table method, with 41 patients in each group. Patients in both groups received total knee replacement, and patients in the study group were treated with Pie-crusting technology to correct varus deformity. Operation time, intraoperative blood loss and hospital stay were compared between the two groups. The knee varus angle, knee motion, hospital for special surgery knee score (HSS score) and World Health Organization quality of life scale-brief form questionnaire (WHOQOL-100 score) were compared between the two groups before and six months after surgery and the incidence of complications six months after operation was compared between the two groups. Results There were no significant differences in operative time, intraoperative blood loss and hospital stay between two groups (P ＞ 0.05). Six months after surgery, the varus angle of the knee joint in the two groups was lower than that before surgery, but there was no statistical significance in the varus angle of the knee joint between the two groups (P ＞ 0.05). The knee motion of the two groups was higher than that before surgery, and the study group was higher than the control group, the differences were statistically significant (P ＜ 0.05). Six months after surgery, HSS and WHOQOL-100 scores of the two groups were higher than those before surgery, and the study group was higher than the control group, the differences were statistically significant (P ＜ 0.05). Six months after surgery, there was no significant difference in the incidence of complications between two groups (P ＞ 0.05). Conclusion Pie-crusting technology for the treatment of varus deformity in knee arthritis patients during total knee replacement can effectively correct varus deformity, improve knee motion and function, and improve the quality of life, and is safe and reliable.
		2022 Vol. 19 (6): 85-88 [Abstract] ( 49 ) HTML (1 KB) PDF (551 KB) ( 53 )

	89	Clinical effect of relaxation manipulation combined with core muscle training in the treatment of patients with chronic lumbago pain of lumbar disc herniation#br#
		LU Li MA Shuming▲ YAO Yao
		Objective To investigate the clinical effect of relaxation manipulation combined with core muscle training in the treatment of patients with chronic lumbago pain of lumbar disc herniation. Methods A total of 86 patients with chronic lumbago pain due to lumbar disc herniation treated in Fuyang Cancer Hospital of Anhui Province from September 2017 to September 2020 were selected as the research subjects. They were divided into control group and combined group by random number table method, with 43 patients in each group. The control group was treated with core muscle group training, and the combined group was treated with relaxation manipulation combined with core muscle training. The treatment lasted for three months in both groups. Lumbago pain score, Oswestry disability index, clinical efficacy and lumbar curvature were compared between the two groups. Results After treatment, the scores of Japanese Orthopaedic Association in both groups were higher than that before treatment, and the combined group was higher than the control group, the differences were statistically significant (P ＜ 0.05). The Oswestry dysfunction index in both groups was lower than that before treatment, and the combined group was lower than the control group, the differences were statistically significant (P ＜ 0.05). After treatment, the clinical efficacy of the combined group was better than that of the control group, the difference was statistically significant (P ＜ 0.05). After treatment, the lumbar curvature of two groups was higher than that before treatment, and the combined group was higher than the control group, the differences were statistically significant (P ＜ 0.05). Conclusion The relaxation manipulation combined with core muscle training in the treatment of patients with lumbar disc herniation and chronic lumbago pain can relieve pain and enhance lumbar spine function, and have a definite effect, at the same time, it can improve lumbar spine curvature.
		2022 Vol. 19 (6): 89-92 [Abstract] ( 179 ) HTML (1 KB) PDF (579 KB) ( 67 )

	93	Clinical effect of different doses of Letrozole combined with low-dose HMG on infertile patients with polycystic ovary syndrome#br#
		HE Shan1 LIU Dayan2 NING Yan3 CHEN Pengdian3 JIANG Shaoyan1 MA Fei3 WU Jiaman3 WU Fangting1
		Objective To explore the effect of different doses of Letrozole combined with low-dose human menopausal gonadotropin (HMG) on infertile patients with polycystic ovary syndrome (POCS), and to provide guidance for clinical ovulation promotion programs of patients. Methods A total of 189 infertility patients with PCOS who were received routine ovulation induction treatment in Reproductive Center, the Affiliated Shenzhen Maternity and Child Healthcare Hospital, Southern Medical University from January 2018 and December 2020 as research subjects. They were divided into group A (Letrozole 2.5 mg), group B (Letrozole 5.0 mg), and group C (Letrozole 7.5 mg). After five days of Letrozole oral administration from two to five days of menstruation, HMG was intramuscular injected. The levels of luteinizing hormone (LH), estrdiol (E2), and testoserone (T) in each group on human chorionic gonadotrophin (HCG) day; number of follicular maturation days, doses and days of HMG, number of follicular development, endometrial thickness, and the proportion of patients with clinical pregnancy rate, number of miscarriages, number of biochemical pregnancies, number of ovarian hyperstimulation syndrome (OHSS), and number of multiple pregnancies were observed and compared. Results There were no significant differences in endometrial thickness and maximum follicular diameter among three groups on HCG days (P > 0.05); the number of follicular maturation days and days of HMG in groups B and C were longer than those in group A, the doses of HMG were lower than those in group A, and the number of follicles ≥18 mm and ≥15 mm in HCG days were more than those in group A, and the differences were statistically significant (P < 0.05). There were no significant differences in LH and T levels among three groups in HCG days (P > 0.05); E2 levels of HCG days in group B and C were higher than those in group A, and the differences were statistically significant (P < 0.05). No OHSS occurred in three groups. There were no significant differences in the proportion of patients with clinical pregnancy, multiple pregnancies, miscarriages, and biochemical pregnancies among three groups (P > 0.05). Conclusion Different doses of Letrozole combined with low-doses of HMG can effectively improve follicular growth and development in patients with PCOS ovulation disorder. In PCOS infertile patients, Letrozole 5.0 mg is taken orally from the two to five days of menstruation for five days, after five days, combined with HMG, the treatment effect is satisfactory, the number of ovulation induction days is short, the incidence of OHSS is low, and the clinical pregnancy rate is high, which had high clinical application value.
		2022 Vol. 19 (6): 93-97 [Abstract] ( 58 ) HTML (1 KB) PDF (597 KB) ( 43 )

	98	Changes and significance of five items of coagulation in third trimester of pregnancy and puerperium under different delivery modes#br#
		ZHANG Jing ZHANG Lin REN Weijuan
		Objective To investigate the changes and significance of five items of coagulation in third trimester of pregnancy and puerperium under different delivery modes in order to the prevention and treatment of obstetric venous thromboembolism. Methods The clinical data of 1216 healthy single parturient women who delivered at term in Yangzhou Maternal and Child Health Hospital from January to May 2019 were retrospectively analyzed. According to the delivery mode, they were divided into delivery group (661 cases), cesarean section group (515 cases) and forceps group (40 cases). Five items of coagulation levels were compared during third trimester of pregnancy (within seven days before delivery) and puerperium (48 h after delivery). Results In the third trimester of pregnancy, there were no significant differences in five items of coagulation among three groups (P > 0.05). During puerperium, thrombin time (TT) in delivery group was shorter than that in the third trimester of pregnancy, fibrinogen (FIB) level was higher than that in the third trimester of pregnancy, D-dimer (DDI) level was lower than that in the third trimester of pregnancy, and the differences were statistically significant (P < 0.05); prothrombin time (PT) and activated partial prothrombin time (APTT) in cesarean section group were longer than those in the third trimester of pregnancy, TT was shorter than that in the third trimester of pregnancy, FIB level was higher than that in the third trimester of pregnancy, DDI level was lower than that in the third trimester of pregnancy, and the differences were statistically significant (P < 0.05); PT in the forceps group was longer than that in the third trimester of pregnancy, and FIB level was higher than that in the third trimester of pregnancy, and the differences were statistically significant (P < 0.05). PT and APTT in cesarean section group were longer than those in delivery group, FIB level was higher than that in delivery group, TT was shorter than that in delivery group; PT and APTT in forceps group were shorter than those in cesarean section group, while FIB level was lower than that in cesarean section group, and the differences were statistically significant (P < 0.05). Conclusion According to the five standards of coagulation for normal people, PT, APTT, and TT of the five items of coagulation in third trimester of pregnancy and puerperium pregnant women are all within the normal range, but FIB and DDI level are higher than the normal range, which is in line with the conclusion of blood hypercoagulability. Routine postpartum screening of DDI levels is not recommended as a basis for predicting venous thromboembolism disease in the puerperium. PT and APTT in puerperium of cesarean delivery pregnancy are longer than those in the third trimester of pregnancy, and the phenomenon of hypocoagulability appears.
		2022 Vol. 19 (6): 98-101 [Abstract] ( 99 ) HTML (1 KB) PDF (516 KB) ( 24 )

	102	Analysis of influencing factors of perimenopausal symptoms after laparoscopic total hysterectomy for benign uterine lesions#br#
		DOU Shulan DING Ling SHI Ruxia▲
		Objective To analyze the influencing factors of perimenopausal symptoms after laparoscopic hysterectomy for benign uterine lesions. Methods A retrospective analysis was performed on the clinical data of 79 benign uterine lesions patients who underwent laparoscopic total hysterectomy in Changzhou Second People’s Hospital Affiliated to Nanjing Medical University from March 2018 to March 2020. The levels of sex hormones were measured before operation, one month after operation, and one year after operation, the modified Kupperman score scale was used to assess perimenopausal symptoms, the incidence of perimenopausal symptoms in patients with benign lesions undergoing laparoscopic total hysterectomy for one year after operation was counted, the influencing factors of perimenopausal symptoms in patients with benign lesions undergoing laparoscopic total hysterectomy were analyzed. Results A total of 79 patients were followed up for one year, and one patient was lost, which was not included in the statistics. One year after operation, the levels of estradiol, progesterone, and testosterone in patients with benign lesions undergoing laparoscopic total hysterectomy were lower than those of one month after operation and before operation, the levels of follicle stimulating hormone and luteinizing hormone were higher than those of one month after operation and before operation, and the differences were statistically significant (P < 0.05); one month after operation, the levels of estradiol, progesterone, and testosterone in patients with benign lesions undergoing laparoscopic total hysterectomy were lower than those before operation, the levels of follicle stimulating hormone and luteinizing hormone were higher than those before operation, and the difference were statistically significant (P < 0.05). One year after operation, perimenopausal symptoms occurred in 31 patients, and the incidence rate was 39.74%. Menopause and the levels of estradiol, progesterone, follicle stimulating hormone, luteinizing hormone, and testosterone were significantly different in patients with and without perimenopausal symptoms of one month after operation (P < 0.05). Menopause and the levels of estradiol, progesterone, and testosterone were independent risk factors for perimenopausal symptoms patients with benign lesions undergoing laparoscopic total hysterectomy (OR > 1, P < 0.05). Conclusion The levels of serum estradiol, progesterone, and testosterone are abnormally decreased, and the levels of follicle stimulating hormone and luteinizing hormone are abnormally increased in patients with benign lesions undergoing laparoscopic total hysterectomy, moreover, such patients are prone to perimenopausal symptoms. serum estradiol, testosterone, and progesterone levels are independent risk factors for perimenopausal symptoms in patients with benign lesions undergoing laparoscopic total hysterectomy.
		2022 Vol. 19 (6): 102-105,134 [Abstract] ( 107 ) HTML (1 KB) PDF (644 KB) ( 31 )

	106	Effect of Gennadol Injection combined with Dexamethasone in the treatment of sudden deafness and its effect on serum ET, sVCAM-1 and AECA levels#br#
		ZHU Liping1 TAN Xiaoye2▲ KUAI Yebin1 SHAO Binghuan1
		Objective To investigate the curative effect of Gennadol Injection combined with Dexamethasone in the treatment of sudden deafness and the effects on serum endothelin (ET), soluble vasccular cell adhesion molecule 1 (sVCAM-1) and anti-endothelial cell antibody (AECA). Methods A total of 106 patients with sudden deafness admitted to Changzhou Maternal and Child Health Hospital of Jiangsu Province from June 2018 to April 2021 were selected as the research subjects, and they were divided into study group and control group according to random number table method, with 53 patients in each group. The control group was given Dexamethasone on the basis of conventional treatment, while the research group was given Nandol Injection on the basis of the control group. Both groups maintained administration for one week. Serum ET levels were detected by radioimmunoassay, serum sVCAM-1 and AECA levels were detected by double-antibody sandwich enzyme-linked immunosorbent assay before and three days after treatment, and clinical efficacy, symptom improvement time, and adverse drug reactions were compared between the two groups. Results During the treatment, two cases in the control group dropped out, and finally 51 cases in the control group and 53 cases in the study group were included. After treatment, the expression levels of ET, sVCAM-1, and AECA in serum of two groups were lower than before treatment, and the study group was lower than the control group, the differences were statistically significant (P ＜ 0.05). The clinical efficacy of the study group was better than that of the control group, and the difference was statistically significant (P ＜ 0.05). The symptom improvement time of the study group was shorter than that of the control group, and the difference was statistically significant (P ＜ 0.05). There was no significant difference in the incidence of total adverse reactions between the two groups (P ＞ 0.05). Conclusion Treatment of patients with sudden deafness with Gennadol Injection combined with Dexamethasone can shorten the symptom improvement time of patients, effectively reduce the expression levels of ET, sVCAM-1, and AECA in serum of patients, with good clinical efficacy and safety.
		2022 Vol. 19 (6): 106-109 [Abstract] ( 210 ) HTML (1 KB) PDF (571 KB) ( 26 )

	110	Application effect of Ambroxol Hydrochloride in nasal endoscopy after chronic sinusitis complicated with nasal polyp#br#
		ZHANG Yaoting GU Dongsheng▲ LI Peizhong
		Objective To study the application effect of Ambroxol Hydrochloride in nasal endoscopy after chronic sinusitis with nasal polyp. Methods A total of 210 patients with chronic sinusitis complicated with nasal polyps in the Affiliated Huaian NO.1 People’s Hospital of Nanjing Medical University from January 2017 to January 2020 were selected as the research subjects, and they were divided into observation group and control group according to random number table method, with 105 cases in each group. Both groups received endoscopic sinus surgery, the control group received conventional glucocorticoids after surgery, and the observation group was additionally given Ambroxol Hydrochloride, Both groups lasted for one month. The clinical efficacy of the two groups was compared. Symptom scores and serum levels of procalcitonin (PCT), hypersensitive C-reactive protein (hs-CRP) and interleukin-6 (IL-6) were compared between the two groups before and after treatment. The recurrence of nasal polyp in two groups was recorded within one year. Results After treatment, the total effective rate of observation group was significantly higher than that of control group, the difference was statistically significant (P ＜ 0.05). After treatment, the scores of nasal obstruction, runny nose, and olfactory disorder in two groups were lower than those before treatment, and the observation group was significantly lower than the control group, the differences were statistically significant (P ＜ 0.05). After treatment, the levels of PCT, hs-CRP, and IL-6 in two groups were significantly decreased compared with before treatment, and the observation group was significantly lower than the control group, the differences were statistically significant (P ＜ 0.05). One year after treatment, the recurrence rate of nasal polyp in the observation group was significantly lower than that in the control group, the difference was statistically significant (P ＜ 0.05). Conclusion Ambroxol Hydrochloride is effective in the treatment of chronic sinusitis complicated with nasal polyp, which can improve nasal congestion and other symptoms and reduce the risk of nasal polyp recurrence.
		2022 Vol. 19 (6): 110-113 [Abstract] ( 100 ) HTML (1 KB) PDF (551 KB) ( 40 )

	114	Thinking on the construction of health supervision and management mode under the new situation#br#
		GUO Aiping
		The development status of the current health supervision mode, facing problems, and new challenges are analyzed, it is proposed that the bottom line of health management safety should be maintained at the current stage by strengthening the team construction, clarifying the key points of supervision, and exploring new supervision methods; this paper analyzes the problems of current information construction and the tasks of digital transformation construction, puts forward to solve the problem of health supervision development, comprehensively promotes the digital transformation and development of health supervision, accelerates the completion of health supervision digital infrastructure, connects and applies urban digital base resources, establishes digital supervision rules, and reengineer and reconstruct supervision mode; it is proposed to adhere to the new development concept in the long term, and form a new management pattern of health supervision.
		2022 Vol. 19 (6): 114-117 [Abstract] ( 67 ) HTML (1 KB) PDF (655 KB) ( 46 )

	118	Overview of systematic reviews of invigorating qi and warming yang, promoting blood circulation and inducing diuresis in treating chronic heart failure#br#
		LI Jiazhuo WANG Yudan SUI Yanbo ZHANG Hongting ZOU Guoliang GUO Dandan
		Objective To evaluate methodological quality of systematic evaluation of invigorating qi and warming yang, promoting blood circulation and inducing diuresis in treating chronic heart failure, and evaluate the outcome indicators included in the systematic review. Methods The databases of CNKI, Wanfang, VIP, PubMed and Cochrane Library were searched by computer. The systematic evaluation of invigorating qi and warming yang, promoting blood circulation and inducing diuresis in treating chronic heart failure was searched. The retrieval time limit was from the establishment of the database to December 2020. Data was independently screened and extracted by two researchers, in case of any objection, it shall be decided by the third person, then the methodological quality of the included literature was evaluated with AMSTAR2 scale, GRADE classification was used to evaluate the quality of evidence included in the literature. Results Finally, 14 systematic evaluations were included, the methodological quality of the included studies was evaluated with AMSTAR2 scale, seven items were reported completely, five items were not reported, and the overall quality was low. GRADE was used to evaluate the outcome indicators, the evidence grades of outcome indicators were medium quality, low quality and very low quality. Conclusion Invigorating qi and warming yang, promoting blood circulation and inducing diuresis can effectively treat chronic heart failure. However, there are some problems in the retrieved system evaluation, such as low quality of methodology and low quality of evidence. High quality research should be carried out in the future. In addition, the writing of system evaluation should be standardized and objective.
		2022 Vol. 19 (6): 118-122,146 [Abstract] ( 71 ) HTML (1 KB) PDF (928 KB) ( 49 )

	123	Bibliometric analysis of Danhong Injection based on CiteSpace
		LIAN Yanjie1 LIU Hongxu1 WU Cong1 ZHOU Mingxue2 KONG Jinli1
		Objective To explore the development status and research hotspots of Danhong Injection and predict the future research direction through bibliometrics. Methods Taking CNKI as the data source, the literatures related to Danhong Injection were retrieved from January 2010 to December 2020. CiteSpace 5.5.1 software was used to analyze the author, organization and key words of the literatures, and a visual map was drew. Results A total of 3814 documents were obtained, and four research teams and three regional research cooperation institutions were obtained through econometric analysis. “Acute cerebral infarction”, “cerebral infarction” and “coronary heart disease” were the most frequently used keywords. “Neurological function”, “cerebral infarction” and “cardiac function” were the keywords with the highest highlight intensity. The emergence intensity of keywords such as “clinical effect”, “neurological function” and “systematic evaluation” continued to today. Conclusion At present, the research focus of Danhong Injection is acute cerebral infarction and coronary heart disease, mechanism and safety may be the focus of research in the future.
		2022 Vol. 19 (6): 123-126 [Abstract] ( 226 ) HTML (1 KB) PDF (1962 KB) ( 39 )

	127	Effect of Ditan Huayu Decoction on serum NO and ET levels in patients with acute cerebral infarction of wind-phlegm invading collaterals syndrome#br#
		WANG Yuan XU Haogang▲
		Objective To investigate the effect of Ditan Huayu Decoction on serum nitric oxide (NO) and endothelin (ET) levels in patients with acute cerebral infarction of wind-phlegm invading collaterals syndrome. Methods From May 2017 to June 2020, 102 patients with acute cerebral infarction of wind-phlegm invading collaterals syndrome in Jiangyin Hospital of Traditional Chinese Medicine in Jiangsu Province were selected and divided into control group and study group according to random number table method, with 51 cases in each group. Control group was treated with conventional Western medicine, and study group was treated with Ditan Huayu Decoction on the basis of the treatment of control group. Two groups continued treatment for four weeks. Traditional Chinese medicine symptom score, serum NO and ET levels of wind-phlegm invading collaterals syndrome were compared between two groups before and after treatment. Clinical efficacy and safety of two groups were compared. Results Before treatment, there was no significant difference in traditional Chinese medicine symptom score, serum NO and ET levels between two groups (P > 0.05). After treatment, traditional Chinese medicine symptom score and serum NO level of wind-phlegm invading collaterals syndrome in two groups were lower than those before treatment, and study group was lower than that control group, the differences were statistically significant (P < 0.05). After treatment, the levels of serum ET in two groups were higher than those before treatment, and study group was higher than that control group the differences were statistically significant (P < 0.05). Total clinical effective rate of study group was higher than that of control group, the difference was statistically significant (P < 0.05). There was no significant difference in the incidence of adverse reactions between the two groups during treatment (P > 0.05). Conclusion Ditan Huayu Decoction is effective in treating patients with acute cerebral infarction of wind-phlegm invading collaterals syndrome. It can improve the vascular endothelial function of patients, and it is safe and reliable.
		2022 Vol. 19 (6): 127-130 [Abstract] ( 213 ) HTML (1 KB) PDF (577 KB) ( 43 )

	131	Effect of Longgu Muli Powder combined with Kanghuier foam dressing in the treatment of incontinence-related dermatitis#br#
		PENG Zhili LU Baorong HUANG E
		Objective To explore the effect of Longgu Muli Powder combined with Kanghuier foam dressing in the treatment of incontinence-related dermatitis (IAD). Methods One hundred and six patients with IAD admitted to Intensive Care Unit of Rugao Hospital of Traditional Chinese Medicine in Jiangsu Province from February 2019 to April 2021 were selected and divided into control group and study group according to random number table method, with 53 cases in each group. Both groups were given routine treatment, control group was treated with Kanghuier foam dressing, study group was treated with Longgu Muli Powder on the basis of control group. Both groups were treated for seven days. Clinical symptom scores of two groups were compared before and after treatment. Clinical efficacy, skin healing time, adverse reactions and recurrence were compared between two groups. Results After treatment, clinical symptom scores of two groups were lower than those before treatment, and study group was lower than control group, the differences were statistically significant (P < 0.05). Clinical effect of study group was better than that of control group, the difference was statistically significant (P < 0.05). Skin healing time of grade Ⅱ and Ⅲ patients in study group were shorter than those in control group, the differences were statistically significant (P < 0.05). There was no significant difference in the incidence of total adverse reactions and recurrence between two groups (P > 0.05). Conclusion Longgu Muli Powder combined with Kanghuier foam dressing in the treatment of IAD can improve clinical symptoms of patients, enhance clinical efficacy, accelerate skin healing, with good safety.
		2022 Vol. 19 (6): 131-134 [Abstract] ( 122 ) HTML (1 KB) PDF (590 KB) ( 43 )

	135	Discussion on traditional Chinese medicine treatment of malignant ascites from the theory of “once the pectoral qi runs, the water qi is dispersed”
		SUO Feiya1 CHEN Chen1 YANG Zhenhuan1 ZHU Xiaoran1 YAO Shukun2
		“Once the pectoral qi runs, the water qi is dispersed” is the classical theory of treatment of water pathogen disease in Jingui Yaolue. The pectoral qi governs qi and blood in the body, the physical characteristics of malignant tumour patients, such as deficiency in root and excess in superficiality, qi stagnation and phlegm stasis, and internal binding of toxin factor, lead to the abnormal operation of the pectoral qi in the body, which affects the functions of internal organs and meridians, leading to the production of malignant ascites. Under the guidance of the theory of “Once the pectoral qi runs, the water qi is dispersed”, the malignant ascites was classified by traditional Chinese medicine syndrome differentiation, including the types of qi deficiency and water stagnation, qi stagnation and water stagnation, water-heat interconnection, yang deficiency and water stagnation, and stasis and water interconnection, and discusses the traditional Chinese medicine treatment of malignant ascites, including invigorating qi and disinhibiting water, activating qi and disinhibiting water, clearing heat and and disinhibiting water, warming yang and disinhibiting water, and activating blood and disinhibiting water, pectoral qi can function normally, so that malignant ascites could be dispersed.
		2022 Vol. 19 (6): 135-138 [Abstract] ( 118 ) HTML (1 KB) PDF (582 KB) ( 136 )

	139	Treatment of Taiyang disease in Treatise on Cold Pathogenic Diseases from the perspective of body fluid#br#
		XING Jiaxing1 ZHOU Yulong1 SI Tinglin2
		In order to explore the treatment of body fluid in Taiyang disease of Treatise on Cold Pathogenic Diseases, through combing the sweating method, the deteriorated cases of missweating, misvomit, and misdiarrhea in Taiyang disease in Treatise on Cold Pathogenic Diseases, the records of fluid theory in ancient books and later physicians, on the law of syndrome and treatment of fluid in Taiyang disease, it is concluded that fluid is the carrier of the function embodiment of nutrient qi and defensive qi. The hyperactivity of defensive qi can accumulate the body fluid on the body surface, which is the basic condition for the application of sweating method, and hinders the body fluid generation, distribution, and excretion could cause the production of water-fluid. According to the different symptoms, body fluid of repletion, deficiency, formation barriers, transport barriers, and excretion barriers, and so on were discussed and treated, in order to adopt the treatment of promoting sweating to release the external, regulating and harmonizing the nutrient and defense, fortifying the spleen and unblocking yang to resolve dampness, and so on, and from the perspective of body fluid in Taiyang disease of Treatise on Cold Pathogenic Diseases, it can be connected with treatment based on disease differentiation of Taiyang diseases and their changes of Zhang Zhongjing, which has certain significance for improving clinical treatment based on disease differentiation.
		2022 Vol. 19 (6): 139-142 [Abstract] ( 60 ) HTML (1 KB) PDF (610 KB) ( 72 )

	143	Zhang Limei’s clinical experience in treating palpitation with traditional Chinese medicine#br#
		LIU Meihan LI Xiaoning WANG Yifan ZHANG Limei
		Arrhythmia is a common clinical cardiovascular disease or complication. It belongs to the category of “palpitations” and “stunned” in traditional China medicine. Clinical treatment is often very tricky, and traditional Chinese medicine is effective in treating palpitations. Director Zhang Limei is a well-known cardiovascular expert in Guang’anmen Hospital, China Academy of Chinese Medical Sciences, and has unique clinical experience in the treatment of arrhythmia. This article summarizes Director Zhang Limei’s experience in the treatment based on syndrome differentiation. Professor Zhang Limei believes that the pathogenesis of palpitations is deficient root and excessive superficial, and the fundamental pathogenesis is deficiency of qi and yin. Among them, the deficient root is deficiency of qi, blood, yin, and yang, and the excessive superficial is excess of phlegm dampness, phlegm stasis, and phlegm fire. Traditional Chinese medicine is based on the principles of replenishing qi and nourishing yin, and warming blood vessels. Clinical emphasis on holism, as well as the use of the methods of tranquilizing spirit to calm mind, soothing liver and regulating qi, invigorating spleen and resolving phlegm, promoting qi and activating blood, and extinguishing wind and restore pulsation, have significant effects, and worthy of promotion.
		2022 Vol. 19 (6): 143-146 [Abstract] ( 104 ) HTML (1 KB) PDF (637 KB) ( 203 )

	147	Clinical effect of Chinese medicine fumigation combined with acupuncture in the treatment of peripheral facial paralysis#br#
		WANG Jing ZHU Jing TONG Beibei SUN Jinglin ZHANG Xiaoyuan HONG Wanwan
		Objective To investigate the clinical effect of Chinese medicine fumigation combined with acupuncture in the treatment of peripheral facial paralysis, which in order to provide reference for clinical application. Methods A total of 80 patients with peripheral facial paralysis treated in Bozhou Hospital of Traditional Chinese Medicine from June 2018 to October 2020 were selected as the study subjects. According to the random number table method, they were divided into study group and control group, 40 cases in each group. The control group was treated with acupuncture, the study group were treated with traditional Chinese medicine fumigation on the basis of control group. After two weeks of treatment, clinical efficacy, H-B facial nerve function score, facial disability Index (FDI) scale score, and Sunnybrook (Toronto) facial nerve assessment system (SFGS) score were analyzed and compared between the two groups. Results The clinical efficacy of the study group was better than that of the control group (P ＜ 0.05); after treatment, H-B facial nerve function score decreased in the two groups, and the study group was lower than that of he control group (P ＜ 0.05); after treatment, facial disability index physics function, facial disability index society function, and SFGS scores increased in the two groups, and the study group were higher than those of the control group (P ＜ 0.05). Conclusion Chinese medicine fumigation combined with acupuncture is effective in treating patients with peripheral facial paralysis, which can obviously improve the facial nerve function, and reduce the facial disability condition.
		2022 Vol. 19 (6): 147-149,154 [Abstract] ( 204 ) HTML (1 KB) PDF (604 KB) ( 181 )

	150	Application effect of “3 H” combined with “five step” method in elderly hip arthroplasty#br#
		HU Qin SHI Juan▲ ZHU Xiaoqin SUN Chao
		Objective To explore the application effect of “3 H” combined with “five step” method applied in elderly hip replacement surgery. Methods A total of 120 elderly patients undergoing hip replacement in the Affiliated Jiangning Hospital of Nanjing Medical University from November 2019 to November 2020 were selected and they were divided into two groups by random number table method, with 60 patients in each group. The control group received routine intervention, and the observation group received “3 H” combined with “five step” intervention. The functional recovery of hip joint six months after surgery, and daily living ability, pain degree, and quality of life were compared between the two groups one day after surgery and at discharge. Results Six months after surgery, the excellent and good rate of hip function in the observation group was higher than that in the control group (P ＜ 0.05). There were no significant differences in daily living scale (ADL) score and visual analog scale (VAS) score between the two groups on one day after surgery (P ＞ 0.05). The ADL scores at discharge in both groups were higher than those on one day after surgery, the VAS score was lower than that on one day after surgery, and the ADL score in observation group was higher than that in control group, and the VAS score was lower than that in control group (P ＜ 0.05). There were no significant differences in physiological, psychological, environmental, and social relationship scores between the two groups on one day after surgery (P ＞ 0.05). The scores of physiological, psychological, environmental, and social relationship in both groups at discharge were higher than those one day after surgery, and the observation group was higher than those in the control group (P ＜ 0.05). Conclusion The “3 H” combined with “five step” method used in the elderly hip replacement surgery can promote the recovery of hip joint function, improve the ability of daily living and quality of life, reduce the degree of pain, and reduce the occurrence of complications.
		2022 Vol. 19 (6): 150-154 [Abstract] ( 234 ) HTML (1 KB) PDF (672 KB) ( 114 )

	155	Effect of Snyder hope theory combined with WeChat support on the hope level and rehabilitation self-efficacy of patients after radical gastric cancer surgery#br#
		YU Shuyuan SUN Ying▲
		Objective To explore the effect of Snyder’s hope theory combined with WeChat support on the rehabilitation of patients after radical gastric cancer surgery. Methods Ninety-six patients after radical gastric cancer who were admitted to Huaian First People’s Hospital from April 2018 to October 2019 were selected and they were divided into intervention group and control group by random number table method. with 50 cases in each group. The control group was given conventional nursing intervention, and the intervention group received combined with the application of Snyder hope theory and WeChat support on the basis of conventional nursing intervention. Intervention for six months, the hope level, rehabilitation self-efficacy, and quality of life were compared between the two groups. Results Six months after intervention, the two groups attitude towards reality and future, maintaining close relationship with others, positive action score and total score of hope level were higher than before intervention, and the intervention group was higher than the control group (P ＜ 0.05). The scores of emotional management, symptom management, daily life management, rehabilitation information acquisition and application, rehabilitation training and skill cultivation and total rehabilitation self-efficacy of the two groups were higher than before intervention, and the intervention group was higher than the control group (P ＜ 0.05). The scores of social/family status, emotional status, functional status and quality of life in the intervention group were higher than those before intervention and higher than those in the control group (P ＜ 0.05). Conclusion Snyder hope theory combined with WeChat support can help enhance the hope of patients after radical gastric cancer surgery, rehabilitation self-efficacy, and improve the quality of life.
		2022 Vol. 19 (6): 155-158，178 [Abstract] ( 201 ) HTML (1 KB) PDF (702 KB) ( 88 )

	159	Mediating effect of family function on self-efficacy and psychological distress in tuberculosis patients#br#
		CHEN Han1 ABULAITI·Gulisumuhan2 YANG Fengqin3 CHEN Weixing4 WANG Meixin5
		Objective To explore the relationship between family function, self-efficacy, and psychological distress in patients with tuberculosis. Methods A total of 274 tuberculosis patients in the department of respiratory of a hospital in Xinjiang were selected from November 2020 to April 2021, and the family functioning scale, general self-efficacy scale, and simple psychological status rating scale were used for questionnaire survey. Pearson correlation was used for correlation analysis of each variable, and bootstrap method was used to verify the mediation effect model. Results There was a positive correlation between family functioning and self-efficacy (r = 0.351, P ＜ 0.01), and a negative correlation between psychological distress and self-efficacy and family functioning (r = -0.327, -0.520, P ＜ 0.01). The mediating effect of family function on the prediction of self-efficacy, and psychological distress was 55.04%. Conclusion The psychological distress of tuberculosis patients is mild, self-efficacy and family functioning are inverse predictors of psychological distress, and self-efficacy indirectly affectes psychological distress through family functioning.
		2022 Vol. 19 (6): 159-162 [Abstract] ( 113 ) HTML (1 KB) PDF (926 KB) ( 12 )

	163	Mediating effect of breastfeeding self-efficacy between social support and postpartum depression in maternal#br#
		CHEN Yanli GUO Nafei▲ ZHANG Lan
		Objective To explore the mediating effect of breastfeeding self-efficacy between maternal social support and postpartum depression in maternal. Methods From June 2019 to April 2020, 2606 cases of puerpera in the Shanghai First Maternal and Infant Health Hospital, Tongji University School of Medicine were selected as the study subjects by convenience sampling method. General data questionnaire, Social Support Rating Scale (SSRS), Breastfeeding self-efficacy scale (BSES), and edinburgh postpartum depression Scale (EPDS) were used. SPSS 22.0 and AMOS 21.0 were used for statistical analysis. Correlation analysis was used to understand the relationship between social support, breastfeeding self-efficacy and postpartum depression, and structural equation model was constructed to verify the mediating effect of breastfeeding self-efficacy. Results A total of 2606 questionnaires were distributed in this study, with 2552 valid questionnaires returned, the effective recoveing was 97.93%. The score of social support was (28.05±5.30) points, the score of breastfeeding self-efficacy was (110.80±22.88) points, and the score of postpartum depression was 7.00(3.00,12.00)points, correlation analysis showed that there was a positive correlation between social support and breastfeeding self-efficacy (r = 0.276, P < 0.01), there was a negative correlation between self-efficacy of breastfeeding and postpartum depression (r = -0.281, P < 0.01), and there was a negative correlation between self-efficacy of breastfeeding and postpartum depression (r = -0.379, P < 0.01), the percentage of intermediary effect in total effect was 32.36%. Conclusion Breast-feeding self-efficacy is partly mediating between social support and postpartum depression in maternal.
		2022 Vol. 19 (6): 163-166 [Abstract] ( 160 ) HTML (1 KB) PDF (730 KB) ( 100 )

	167	Effect of inflatable insulation blanket warming up the apper body in patients undergoing thoracoscopic surgery in lateral decubial position#br#
		XU Yu
		Objective To approach influence of lateral decubitus thoracoscopic surgery patients by inflatable insulation blanket in warming up the upper body. Methods A total of 256 patients who underwent thoracoscopic surgery in lateral decubitus position from February 2018 to January 2021 in Quzhou People’s Hospital, Zhejiang Province were selected as the study subjects, they were divided into control group and observation group according to random number table method, with 128 cases in each group. Inflatable insulation blanket was used to warm the lower part in the control group and inflatable insulation blanket was used to worm the upper part in the observation group. Body temperature, stress response, at different time points postoperative recovery time and incidence of adverse reactions were observed in two groups. Results The body temperature of two group patients into the operating room, at the beginning of operation were compared, and the difference was no statistical significance (P ＞ 0.05), the body temperature of the observation group was higher than that of the control group at 60 min after surgery, at the end of surgery and after anesthesia, the differences were statistically significant (P ＜ 0.05). There were statistically significant differences between groups, time points and interaction (P ＜ 0.05). Comparison of serum cortisol (Cor) between the two groups at the beginnig of the operation, 30 min of operation, 72 h after surger, the differences was statistically significant (P ＜ 0.05). Cor in the observation group was lower than those in the control group 30 min and 72 h after surgery, the differences was statistically significant (P ＜ 0.05). The time of tracheal extubation and thoracic drainage tube extubation in the observation group were shorter than those in the control group, and the differences were statistically significant (P ＜ 0.05). The incidence of intraoperative hypothermia and postoperative chills in the observation group was lower than that in the control group, and the differences were statistically significant (P ＜ 0.05). Conclusion Inflatable blanket upper body heating can improve recovery efficiency and reduce the incidence of hypothermia and chills when applied to patients with lateral assisted thoracoscopic surgery.
		2022 Vol. 19 (6): 167-170 [Abstract] ( 106 ) HTML (1 KB) PDF (547 KB) ( 29 )

	171	Application of structural group psychotherapy combined with social interaction training in patients with post-stroke depression#br#
		ZENG Ning1 CHEN Kehan1 ZHENG Hongli2 LIU Zuoyan1▲
		Objective To observe the application effect of structural group psychotherapy combined with social interaction training in patients with post-stroke depression. Methods A total of 120 patients with post-stroke depression treated in West China Hospital Sichuan University from January to June 2019 were selected as the research subject, they were divided into study group and control group by a random number table method, with 60 cases in each group; the control group received social communication training, and the study group received structured group psychotherapy on the basis of the control group, both groups received continuous intervention for eight weeks; the psychological status (self-rating Depression scale [SDS], self-rating anxiety scale [SAS] )， and social function (scale of social function deficit for mantal disorders [SSFD-MD] ) of the two groups were analyzed and compared before intervention and eight weeks after intervention. Results After eight weeks of intervention, SDS and SAS scores of both groups were lower than those before intervention, and the study group was lower than the control group (P ＜ 0.05); eight weeks after intervention, the scores of social participation, family life, self-care, getting along with others, understanding and communication in SSFD-MD of both groups were higher than those before intervention, and the study group was higher than the control group (P ＜ 0.05). Conclusion Structural group psychotherapy combined with social interaction training can reduce the depression and anxiety of patients with post-stroke depression, and improve their social function.
		2022 Vol. 19 (6): 171-174 [Abstract] ( 140 ) HTML (1 KB) PDF (565 KB) ( 59 )

	175	Effect of integrated management mode of medical care on the quality and satisfaction of postoperative care of hemodialysis patients with arteriovenous internal fistula#br#
		ZHAO Chunyu LI Sihui BAI Yang
		Objective To explore the influence of integrated management mode of medical care on postoperative nursing quality and satisfaction of hemodialysis patients with arteriovenous internal fistula, and to provide theoretical reference for clinical practice. Methods A total of 90 patients with chronic renal failure who had been treated by arteriovenous internal fistula to maintain hemodialysis in Liaoning Provincial People’s Hospital from January 2018 to December 2020 were selected, they were divided into control group (45 cases) and observation group (45 cases) according to random number table method, the control group received routine nursing management, and the observation group received integrated management mode of medical care based on the control group. The nursing quality, complication rate and nursing satisfaction of the two groups were compared. Results The scores of service attitude, nursing initiative, ward management, professional skills, and communication skills in the observation group were higher than those in the control group, and the differences were statistically significant (P ＜ 0.05). The total incidence of complications in observation group was lower than control group, and the difference was statistically significant (P ＜ 0.05). The total nursing satisfaction of observation group was higher than control group, and the difference was statistically significant (P ＜ 0.05). Conclusion The integrated management mode of medical care is beneficial to improve the quality of postoperative care for arteriovenous fistula, reduce complications and improve satisfaction.
		2022 Vol. 19 (6): 175-178 [Abstract] ( 152 ) HTML (1 KB) PDF (596 KB) ( 148 )

	179	Comparison of guidelines for endovascular recanalization therapy in the incipient stage of acute ischemic stroke between China and Republic of Korea#br#
		LI Daijun1 WANG Xinzhi2
		Endovascular recanalization therapy (ERT) has been widely used in the treatment of incipient stage of acute ischemic stroke. The application of ERT in patients with acute ischemic stroke is gaining increasing attention from China and Republic of Korea. The causes of the difference between the two countries are analyzed by comparing the ERT guidelines of acute ischemic stroke in China and Republic of Korea. Comparison and analysis are made from four perspectives: evidence level, recommendation intensity, content, mechanical thrombectomy, and benefit of patients, the difference between China and Republic of Korea focuses on the patient screening method of mechanical embolization therapy. It provides some reference for the clinical application of ERT and the update of guidelines in China and Republic of Korea.
		2022 Vol. 19 (6): 179-182,186 [Abstract] ( 76 ) HTML (1 KB) PDF (693 KB) ( 87 )

	183	Application of project cost accounting in declaration of medical service price items in public hospitals#br#
		LI Lin1 ZHOU Wei2▲
		The price management of medical service project is the key link of the operation management of medical institutions, and also an important way to improve the income compensation of medical institutions, which plays an extremely important role and significance for the sustainable development of medical institutions. By analyzing the policy basis of price management of medical service items, this paper fully demonstrates the method and effect of project cost accounting in price declaration of medical service items, and takes medical examination item “X methylation detection” as an example to calculate project cost data, providing scientific basis for accurate pricing of medical service items. Using project cost accounting as a management tool to declare the price of medical service items that reasonably reflect the value of new technology can give necessary income compensation to diagnosis and treatment technology, which is conducive to strengthening the connotation construction of medical institutions and speeding up the clinical application of new technology and the construction of superior disciplines. At the same time, medical institutions can carry out targeted differential cost control according to the cost status of each project, so as to rationally optimize the allocation of resources and ensure the core competitiveness and economic benefits of medical institutions.
		2022 Vol. 19 (6): 183-186 [Abstract] ( 70 ) HTML (1 KB) PDF (566 KB) ( 49 )

	187	Exploration on improving doctor-patient communication ability of medical students in the context of healthy China#br#
		LEI Xiaohua CHEN Guodong
		Constructiing harmonious doctor-patient relationship is an important problem to be solved urgently in the development of China’s health cause. At present, our country does not pay enough attention to the cultivation of doctor-patient communication, the curriculum system is not scientific enough, the practicality is not strong, and the evaluation system is single. The problem can be solved from the following aspects: attaching importance to the cultivation of doctor-patient communication ability; strengthening the development of doctor-patient communication courses in various aspects; strengthening the practice teaching construction of doctor-patient relationship; developing and improving the training and evaluation system of medical students’ doctor-patient communication ability; strengthening education on medical laws and regulations. In the context of healthy China, medical colleges and universities should make joint efforts to train well-rounded successors of medical career.
		2022 Vol. 19 (6): 187-189 [Abstract] ( 55 ) HTML (1 KB) PDF (452 KB) ( 150 )

	190	Strategies for quality culture construction in higher colleges and universities of traditional Chinese medicine#br#
		CHE Linlin YAN Zhonghong GUO Hongwei
		The quality culture construction strategy of higher universities of traditional Chinese medicine is an important guide for the high-quality development of the school, and it is the basis for the school to carry out quality management activities and quality practice activities. This paper is based on the strategy of constructing quality culture in traditional Chinese medicine colleges and universities, the connotation and constituent elements of “five self” strategy are analyzed in detail. Finally, from the three aspects of the material cultural basis of quality culture, institutional cultural constraints, and behavioral culture assimilation, explore the construction of quality culture practice strategies in higher traditional Chinese medicine colleges and universities, in order to further improve the quality culture in the development of higher traditional Chinese medicine colleges and universities of cohesion, constraint, incentive and radiation role and improve the quality of traditional Chinese medicine personnel training to provide rational support.
		2022 Vol. 19 (6): 190-193，封三 [Abstract] ( 213 ) HTML (1 KB) PDF (677 KB) ( 16 )

	194	Discussion on the management system of traditional Indian medicine#br#
		LI Fuwu CUI Yu WU Feng
		The management system of traditional India medicine adopts a parallel model system, which is similar to the dual medical system in South Korea, but very different from the management system of traditional Chinese medicine in China. The development experience of traditional Chinese medicine proves that the parallel management mode still has its merits today. This paper summarizes the development status of traditional India medicine from the aspects of medical infrastructure, medical practitioners, education and medical services. This study found that the system protected the independence and diversity of traditional Indian medicine. To a large extent, it promoted the development of traditional Indian medicine. Although traditional Indian medicine is currently facing problems of low education quality, low quality of practitioners and low utilization rate, there are still experiences and lessons worth learning in the management of traditional Chinese medicine.
		2022 Vol. 19 (6): 194-封三 [Abstract] ( 52 ) HTML (1 KB) PDF (542 KB) ( 232 )

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