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| Methods for the detection of circulating tumor cells #br# |
| SONG Yuhang1 YANG Xiaolin2 LIU Kang1 SONG Guiqin2 |
1.Institute of Tissue Engineering and Stem Cell Research, Nanchong Central Hospital the Second Clinical Medical College of North Sichuan Medical College, Sichuan Province, Nanchong 637000, China;
2.Biology Teaching and Research Section, School of Basic Medicine, North Sichuan Medical College, Sichuan Province, Nanchong 637000, China |
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Abstract Circulating tumor cells (CTCs) carry important information about tumor genesis, development, and metastasis and are closely associated with tumor metastasis. In order to understand the function and molecular characteristics of CTCs and develop effective surveillance and treatment strategies for cancer, the development of CTCs enrichment and identification technology is a key step. In recent years, great progress has been made in the detection of CTCs in vitro, at the same time, real-time, non-invasive in vivo detection technology has gradually emerged in the market. This paper summarizes the methods of CTCs detection in vitro and in vivo, and puts forward the challenges and strategies of CTCs detection.
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