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2023 Vol. 20, No. 4 Published: 2023-02-05

	4	Bibliometrics and visualization analysis based on CiteSpace hotspots and trends in research of spleen deficiency syndrome
		YU Chang1 XIONG Meng1 SONG Houpan1 QIU Jingyue1 LONG Cailing1 ZENG Meiyan2 YUAN Chengzhi3 TAN Meiling1
		DOI: 10.20047/j.issn1673-7210.2023.04.01
		Objective To explore the CiteSpace was used to visualize the research status, trends and hot spots of spleen deficiency syndrome. Methods Literature related to spleen deficiency syndrome published from the establishment of China National Knowledge Infrastructure and Web of Science database to December 31, 2021 were collected. CiteSpace was used for visualization analysis of author, institution, keyword co-occurrence and emergence, keyword, time graph and time zone graph. Results A total of 2 474 Chinese and 61 English literatures were included. The publication of Chinese and English literature is generally on the rise. The author with the largest number of publications in Chinese literature is Shan Dehong, and English literature was GUANG JI. Liaoning University of Traditional Chinese Medicine published the most Chinese literature, while Shanghai University of Traditional Chinese Medicine published the most English literature. In addition to the subject word, the top three Chinese keywords were animal model, Sijunzi Decoction and epigastric pain, and the top three English keywords were traditional Chinese medicine, Sijunzi Decoction, the gut microbiota, cluster analysis of keywords showed that 15 clusters were obtained in Chinese literature and eight clusters were obtained in English literature, which mainly focused on the treatment of spleen deficiency syndrome, model preparation and pathogenic mechanism of spleen deficiency syndrome. Conclusion The research on spleen deficiency syndrome is mainly domestic research, and the cooperation among various groups needs to be strengthened. The pathogenic mechanism of spleen deficiency syndrome, the preparation of animal models, and the treatment of traditional Chinese medicine are the research hotspots in this field, and the future research trends are metabonomics, the treatment of spleen deficiency gastric cancer and gastric ulcer.
		2023 Vol. 20 (4): 4-10 [Abstract] ( 19 ) HTML (1 KB) PDF (5678 KB) ( 42 )

	11	Ultrasonographic characteristics of abnormal fetal aortic arch diagnosed by prenatal ultrasound
		TANG Juansong1 LI Xinyan1▲ ZHANG Hongxia2 QIN Guican1 TANG Yanni1
		DOI: 10.20047/j.issn1673-7210.2023.04.02
		Objective To investigate the ultrasonographic characteristics of abnormal fetal aortic arch diagnosed by prenatal ultrasound. Methods The echocardiographic data of 168 pregnant women with abnormal fetal aortic arch diagnosed by prenatal ultrasound from June 2018 to June 2021 in Guangxi Zhuang Autonomous Region Maternal and Child Health Hospital were analyzed, and the ultrasonographic characteristics of abnormal aortic arch in the three-vessel trachea section, the long axis section of active bow, and the coronal section at the beginning of descending aorta were summarized. Results In 168 fetuses, 68 cases had right-sided aortic arch and branch deformity, 42 cases had left arch left catheter vagus right subclavian artery, 32 cases had aortic coarctation, 15 cases had aortic arch rupture, and 11 cases had double aortic arch rupture. Conclusion The abnormal aortic arch has characteristic ultrasonographic changes in the three-vessel trachea bow, the long axis section of the active arch, and the coronal section of the descending aorta, which has important clinical value in the diagnosis of abnormal aortic arch.
		2023 Vol. 20 (4): 11-14 [Abstract] ( 22 ) HTML (1 KB) PDF (1782 KB) ( 28 )

	15	Literature measurement and visualization research of abdominal oscillation therapy based on CiteSpace
		WANG Yuqi1 XIAO Yonghua2 CHENG Luyao1 CAI Meiling1 YUAN Yi1 GAN Yena1 ZANG Fuke3 LI Duoduo3
		DOI: 10.20047/j.issn1673-7210.2023.04.03
		[Abstract] Objective To analyze the research characteristics, hot spots, and development trend of abdominal vibration therapy were used by Visualization software CiteSpace. Methods The relevant literatures were retrieved from CNKI, Wanfang, and Vip databases from January 1986 to June 2022, and the authors, institutions, and keywords of relevant researches were analyzed using CiteSpace5.7.R2. Results A total of 245 relevant literatures were included. The number of studies showed an overall rising trend, and the authors with the most papers were Fu Guobing, Guo Sheng, and Li Jiangshan. The research institutions were represented by Oriental Hospital of Beijing University of Chinese Medicine. The top three keywords in frequency were “abdominal vibration therapy”, “massage”, and “abdominal vibration method”, and ten keywords formed clusters, with a total of 14 emergent words. Conclusion The number of research on abdominal oscillation therapy is increasing gradually, and the diseases involved in the research are constantly enriched. The research institutions are mostly concentrated in Beijing, and the exchanges and cooperation between different regions need to be further strengthened. The research focuses on techniques, mechanisms, and clinical studies. The current research trend is to further expand the scope of clinical application and further explore the mechanism of action.
		2023 Vol. 20 (4): 15-20 [Abstract] ( 19 ) HTML (1 KB) PDF (2054 KB) ( 68 )

	21	Study on medication rule of Xingqi Lishui Prescription in Chinese Medical Code based on data mining
		KONG Miao1 LIU Chengshuai1 SONG Qingqiao2 ZHOU Yuping1
		DOI: 10.20047/j.issn1673-7210.2023.04.04
		Objective To explore the medication rule of Xingqi Lishui Prescription in Chinese Medical Code to guide clinical application. Methods The relevant provisions of the Chinese Medical Code (5th edition) were searched and prescriptions were selected by keyword “edema” or “water vapor” or “water disease”. The observed indicators were drug composition, nature, flavours, channel tropism, efficacy and concerted application relation. SPSS Modeler 18.0 and SPSS Statistics 26.0 were used for frequency statistics, association rules, clustering analysis, and other medication rule analysis. Results A total of 127 prescriptions and 144 drugs were included. Fifteen high frequency drugs were found, among which the most common drug properties were bitter, pungent, sweet, warm, and cold, which were mainly attributed to the lung and spleen channels, with the main effect of diuresis and diffusing dampness, regulating qi-flowing and tonifying deficiency. Commonly used concerted application drug groups included Aucklandiae Radix, Arecae Semen, Descurainiae Semen Lepidii Semen, Mori Cortex, and so on. The three cluster prescriptions were mainly for regulating the lung, strengthening the spleen and promoting qi. Complex network analysis found 28 core drugs and one strong link drug (Citri Reticulatae Pericarpium-Mori Cortex). Conclusion The syndrome of lung qi stagnation and middle coke qi stagnation is the indication of regulating qi and diuresis. The formula should adhere to the essence of diuresis and diffusing dampness, and the lung and spleen should be treated together, the channel should be regulated, the spleen should be strengthened and middle focal should be widened, which is the key of the regulating qi and diuresis.
		2023 Vol. 20 (4): 21-24,30 [Abstract] ( 31 ) HTML (1 KB) PDF (1192 KB) ( 175 )

	25	Expression of long non-coding RNA tumor protein translationally-controlled regulator 1-antisenseRNA1 in glioma and its effect on cell proliferation and invasion
		LIU Zhenjie1 LI Xin1 LU Jing2 LIANG Liang1 HU Yaowen1 XIE Jing1 ZHAO Xingang3 YANG Jiankai4
		DOI: 10.20047/j.issn1673-7210.2023.04.05
		Objective To investigate the effect of long non-coding RNA (lncRNA) tumor protein translation regulator 1-antisense RNA1 (TPT1-AS1) on the proliferation and invasion of glioma cells U251. Methods U251 cells were divided into blank control group, negative transfection group, and TPT1-AS1 overexpression group. The blank control group was not treated, and the other two groups were transfected with corresponding plasmids. After 48 hours of transfection, the expression level of TPT1-AS1 in U251 cells of each group was compared; MTT assay was used to determine the proliferation ability of U251 cells; flow cytometry was used to detect the apoptotic ability of U251 cells; Transwell chamber assay was used to detect the invasion ability of U251 cells; scratch test was used to detect the migration ability of U251 cells; the expression of apoptosis (Caspase-3, Bax, Bcl-2) and invasion (matrix metallo proteinases [MMP]-2, MMP-9) related proteins was detected by Western blot. Results There were no significant differences in TPT1-AS1 expression, cell survival rate, cell apoptosis rate, number of invasive cells, scratch healing rate, and protein expressions of Caspase-3, Bax, Bcl-2, MMP-2, and MMP-9 between negative control group and blank control group (P＞0.05). TPT1-AS1 expression level, apoptosis capacity, Caspase-3, and Bax protein expression in TPT1-AS1 overexpression group were higher than those in blank control group, and the differences were statistically significant (P＜0.05). The expression of Bcl-2 protein, cell survival rate, invasion, migration ability, and invasion-related protein in TPT1-AS1 overexpression group were lower than those in blank control group, with statistical significance (P＜0.05). Conclusion TPT1-AS1 has low expression in U251, and high expression of TPT1-AS1 can inhibit the proliferation and invasion of glioma cells.
		2023 Vol. 20 (4): 25-30 [Abstract] ( 18 ) HTML (1 KB) PDF (1575 KB) ( 204 )

	31	Diagnostic value of magnetic resonance neurography for spinal nerve compression in patients with osteoporotic lumbar fracture
		LIU Dan1 CHEN Xiaoyu1 ZUO Xiaohua2 PAN Wei3 ZHOU Changdong1 LU Xiaoqing3 ZHANG Xiaobing1▲
		DOI: 10.20047/j.issn1673-7210.2023.04.06
		Objective To study the diagnostic value of magnetic resonance neurography (MRN) for spinal nerve compression in patients with osteoporotic lumbar fracture. Methods Sixty-seven patients with osteoporotic lumbar fracture admitted to Huaian Second People’s Hospital, Jiangsu Province from January 2018 to December 2021 were selected. All of them underwent magnetic resonance imaging and MRN examination, included sagittal position of lumbar T1 (weighted imaging) WI, sagittal position of T2WI, axial position of T2WI, short time inversion recovery (STIR) sequence, and three dimensional-multiple echo recalled gradient echo (3D-MERGE) sequence. The signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and spinal nerve display score of STIR and 3D-MERGE sequences were compared. With surgical results as the “gold standard”, the diagnostic efficacy of the two sequences for spinal nerve compression was analyzed. Results The SNR and CNR of 3D-MERGE sequence were higher than those of STIR sequence, and the grade of spinal nerve display score was better than STIR sequence (P＜0.05). STIR sequence diagnosis showed six cases of spinal nerve compression and distortion among 67 patients with osteoporotic lumbar fracture, nine cases of 3D-MERGE sequence diagnosis, and ten cases of surgical results. The accuracy of 3D-MERGE sequence in diagnosing spinal nerve compression in patients with osteoporotic lumbar fracture was higher than that of STIR sequence (P＜0.05), but there was no significant difference in sensitivity and specificity between the two sequences (P＞0.05). Conclusion MRN has a high diagnostic value for spinal nerve compression and distortion in patients with osteoporotic lumbar fracture, and can provide scientific and reasonable imaging basis for the diagnosis and treatment of clinical spinal neuropathy.
		2023 Vol. 20 (4): 31-34,46 [Abstract] ( 21 ) HTML (1 KB) PDF (912 KB) ( 54 )

	35	Research progress in the application status and cost-benefit analysis of fracture liaison services in osteoporotic fractures
		WANG Qiaona1 HUANG Qiuhuan2▲ LIU Jia3 LU Liuxue2 ZHOU Landao3 WEI Suyu2
		DOI: 10.20047/j.issn1673-7210.2023.04.07
		The aging society inevitably increases the incidence of osteoporotic fractures (OPF). OPF with a high risk of secondary fractures and cost of treatment, which seriously threatens the life and property safety of the elderly. However, the number of patients with timely diagnosis of osteoporosis and standardized treatment is still minority. Fracture liaison service (FLS) is an osteoporotic fracture management model advocated and promoted in worldwide by the International Osteoporosis Foundation, which expected to improve the rate of diagnosis, treatment initiation and OPF patients, treatment compliance. It is still in its infancy in China, there are few related studies. But FLS as a high-intensity OPF management model, the high cost may be as an obstacle to the implementation of FLS. The cost-effectiveness of FLS has been extensively studied abroad. This article reviews the application status and cost-effectiveness of FLS in management of osteoporotic fractures aim to provides a reference for the development and promotion of FLS in China.
		2023 Vol. 20 (4): 35-38,51 [Abstract] ( 22 ) HTML (1 KB) PDF (598 KB) ( 45 )

	39	Research progress in modularization and information construction of emergency drug support
		GENG Shuai1 GUAN Xin2 SHI Ning1 GUO Hongju1 CHANG Lirong1▲
		DOI: 10.20047/j.issn1673-7210.2023.04.08
		In order to establish a timely, reasonable and effective emergency drug supply management system, different drug modules are used to supply emergency drugs under special circumstances and emergencies. In this paper, the construction of drug modularization and informationization platform under related events is summarized and discussed and summarized by searching the relevant literature of drug safeguard measures during emergency and drug modularization and informationization construction under special environment and natural disaster. By formulating a corresponding emergency drug module catalog, the rapid response capability of emergency drug supply will be improved, and a sufficient basis will be provided for improving the modular construction of my country’s drug emergency system, strengthening the information construction of drug supply security, and making full use of Internet technology for drug security supply.
		2023 Vol. 20 (4): 39-42 [Abstract] ( 27 ) HTML (1 KB) PDF (631 KB) ( 85 )

	43	Research progress of microRNA in different types of skeletal muscle atrophy
		XIAO Ya HONG Li LI Suting CHEN Mao HUANG Xiaoyu ZHU Fangyi
		DOI: 10.20047/j.issn1673-7210.2023.04.09
		Skeletal muscle atrophy refers to the decrease of skeletal muscle quality and muscle function. Denervation, aging, chronic obstructive pulmonary disease, cancer, and other diseases can induce skeletal muscle atrophy, resulting in a decline in the quality of life of patients and an increased risk of death. However, the underlying mechanism of muscle atrophy is not fully understood. microRNA (miRNA) is a class of non-coding single-stranded RNA molecules encoded by endogenous genes, which are involved in a variety of physiological and pathological processes, including cell proliferation, differentiation, apoptosis, autophagy, tumorigenesis, and even epigenetics. In recent years, there are more and more studies on miRNA in skeletal muscle atrophy, and miRNA is expected to become a new molecular target for the diagnosis and treatment of skeletal muscle atrophy. This article reviews the research progress on the role of miRNA in different types of skeletal muscle atrophy.
		2023 Vol. 20 (4): 43-46 [Abstract] ( 25 ) HTML (1 KB) PDF (488 KB) ( 102 )

	47	Research progress of the application of natural polymer hydrogels in the repair of cartilage defect
		MA Xiaohang1 ZENG Linru1 LUO Gan1 KANG Yi2 GONG Shijie1
		DOI: 10.20047/j.issn1673-7210.2023.04.10
		Cartilage defect is a lesion of hyaline cartilage of a joint caused by disease, trauma， and aging and it is also one of the main pathological features of osteoarthritis (OA). As a chronic degenerative disease OA has been a challenge for clinical orthopedic surgeons. Surgical approaches such as microfracture, articular chondroplasty, and chondrocyte transplantation have been more successful in recent years, but are not yet able to completely heal cartilage damage and are associated with contraindications to surgery, infection, and immune response. The appearance of cartilage tissue engineering has made cartilage regeneration possible, the natural polymer materials based on polysaccharides and proteins, have excellent biocompatibility, degradability, and unique self-healing ability, pointing the way in a new direction for cartilage defect repair. This paper reviews the application of natural polymer hydrogels in cartilage defect repair aiming to provide some theoretical references for cartilage regeneration.
		2023 Vol. 20 (4): 47-51 [Abstract] ( 29 ) HTML (1 KB) PDF (706 KB) ( 293 )

	52	Research progress of autophagy and liver fibrosis and regulation of traditional Chinese medicine
		PENG Yunhe LI Yuan ZHANG Kan HUANG Guye
		DOI: 10.20047/j.issn1673-7210.2023.04.11
		Autophagy is closely related to the development of liver fibrosis. It plays an important role in the hepatic stellate cells activation and affects the development of liver fibrosis through autophagy related proteins and signaling pathways. Many non-coding RNA regulate autophagy exert biological effects in liver fibrosis and may become a new treatment strategy for liver fibrosis. Traditional Chinese medicine can play an anti fibrosis role through the autophagy and regulate autophagy in a dual manner. This paper discusses the traditional Chinese medicine research of autophagy regulation in liver fibrosis, and discusses the shortcomings of the current research, in order to provide a theoretical basis for the further research of autophagy in the prevention and treatment of liver fibrosis with traditional Chinese medicine.
		2023 Vol. 20 (4): 52-55,63 [Abstract] ( 63 ) HTML (1 KB) PDF (610 KB) ( 113 )

	56	Research progress on the relationship between fibroblast growth factor 21 and gestational diabetes mellitus
		ZHANG Qian1 LI Qin2
		DOI: 10.20047/j.issn1673-7210.2023.04.12
		Gestational diabetes mellitus (GDM) is a common pregnancy disease in obstetrics and gynecology. GDM is associated with adverse perinatal outcomes and long-term prognosis of mother and baby. Fibroblast growth factor (FGF) 21, a member of the FGF family, plays an important role in glucose metabolism and lipid metabolism. FGF21 can improve insulin sensitivity, increase glucose uptake in tissues and organs, and play a role in reducing blood glucose. The feasibility of FGF21 as a new blood glucose control drug has become a hot topic in recent years. In this paper, the structural characteristics and physiological functions of FGF21, as well as the research status and application prospect of FGF21 in patients with GDM are summarized. High serum level of FGF21 in pregnant women can be used as a predictor of GDM, and stage analogues have broad research prospects in the treatment of GDM.
		2023 Vol. 20 (4): 56-59 [Abstract] ( 16 ) HTML (1 KB) PDF (424 KB) ( 91 )

	60	Research progress on mechanism of active ingredients of Astragali Radix in the treatment of diabetic nephropathy
		MENG Sixuan1 YAO Xingmei1 WU Xinye1 LI Zhaodong2 WANG Hao1
		DOI: 10.20047/j.issn1673-7210.2023.04.13
		Diabetic nephropathy is a chronic kidney disease caused by diabetes, which is an important cause of end-stage renal failure and even death in patients with diabetes. Astragali Radix has unique advantages in treating diabetic nephropathy. The active ingredients of Astragali Radix in the treatment of diabetic nephropathy involve anti-inflammatory, anti-endoplasmic reticulum stress, regulation of autophagy and other mechanisms. This article briefly reviews the mechanism of Astragali Radix active ingredients in the treatment of diabetic nephropathy in recent years, in order to provide new ideas for clinical and experimental research.
		2023 Vol. 20 (4): 60-63 [Abstract] ( 23 ) HTML (1 KB) PDF (491 KB) ( 292 )

	64	Improvement and reflection on the teaching mode of standardized training for residents in the department of transfusion medicine
		LEI Huifen LI Xiaowei XIAO Jun LI Cuiying
		DOI: 10.20047/j.issn1673-7210.2023.04.14
		Medical technology is becoming increasingly innovative, transfusion medicine is entering a period of rapid development. The rationality and effectiveness of clinical blood use has become an important indicator for the local health administrative departments to assess the medical quality of a hospital. At present, there is no standardized training system for transfusion physicians has been established at the national level. Most hospitals do not have full-time transfusion physicians, nor do they have a unified training program for transfusion physicians. This phenomenon leads to hidden risks in the safe management of patients’ blood transfusion, and fails to guarantee the synchronous development of transfusion medicine and other clinical disciplines. In view of the current deficiencies in transfusion medicine education, this study is conducted to improve the training program of transfusion medicine residents in Beijing Air Force Characteristic Medical Center in several aspects, including the preparation of the Teaching Plan for Standardized Training of Transfusion Medicine Residents, the implementation of diversified teaching, and the improvement of the assessment method of discharge, based on the research of the current situation of teaching and training of transfusion medicine at home and abroad. To explore a new model of standardized training for transfusion physicians and improve the quality of current resident transfusion specialty training. This study also analyze and reflect on the future development of transfusion medicine and standardized training of transfusion physicians.
		2023 Vol. 20 (4): 64-67,80 [Abstract] ( 20 ) HTML (1 KB) PDF (690 KB) ( 208 )

	68	Exploration and application of group therapy in clinical teaching of occupational therapy
		LIU Zhe1 LING Shanshan1 WANG Qiuchun1 HE Yanan2
		DOI: 10.20047/j.issn1673-7210.2023.04.15
		Occupational therapy is an important part of modern rehabilitation medicine. In addition to focusing on cultivating students’ solid medical theoretical knowledge, it also emphasizes practical application. It is a very practical specialty. In order to enrich the clinical teaching practice mode of occupational therapy, ensure the quality of clinical practice teaching, and cultivate comprehensive occupational therapy technical talents, this paper proposes an innovative clinical teaching plan of “six steps of group therapy”, and applies it to clinical teaching of occupational therapy. Through in-depth research and analysis on the teaching design and implementation of group therapy in clinical teaching of occupational therapy, the positive role of group activity teaching in clinical practice of occupational therapy is discussed, and the systematization and improvement of clinical teaching of group occupational therapy are discussed. Standardized theoretical framework, student-centered, optimized curriculum system, reformed teaching methods, trained qualified and excellent occupational therapists, and provided new ideas and new methods for enriching occupational therapy clinical teaching.
		2023 Vol. 20 (4): 68-71,91 [Abstract] ( 23 ) HTML (1 KB) PDF (718 KB) ( 72 )

	72	The application of problem-based learning based reflective teaching in surgical skill teaching
		BI Hai LIU Yuqing HUANG Yi MA Lulin LIU Cheng
		DOI: 10.20047/j.issn1673-7210.2023.04.16
		Objective To explore the application effect of problem-based learning (PBL) based reflective teaching in surgical skill teaching. Methods Twenty clinical medical undergraduates participated in the surgery course in Peking University Health Science Center from August to October in 2020 were selected as the research subjects, and they were divided into the control group and the test group according to the random number table method, with ten students in each group. The control group used traditional teaching methods, and the test group used PBL based reflective teaching methods. After the course, the students’ learning effects were evaluated by means of operation assessment, satisfaction survey and self-evaluation. Results The results of urethral catheterization, surgical knotting and intestinal anastomosis in vitro and satisfaction in the test group were higher than those in the control group, the differences were statistically significant (P＜0.05). The students in the test group scored the highest in self-evaluation, which was the ability of teamwork and problem-solving. Conclusion PBL based reflective teaching method shows a good teaching effect in the surgical skills teaching for undergraduates.
		2023 Vol. 20 (4): 72-75 [Abstract] ( 24 ) HTML (1 KB) PDF (549 KB) ( 175 )

	76	Exploration and application of ideological and political education elements of traditional Chinese medicine surgery curriculum
		LIAO Chengcheng WANG Jinrong ZHANG Yanju YAN Yan ZOU Xuhui LIN Yan
		DOI: 10.20047/j.issn1673-7210.2023.04.17
		Medical students are the backbone of the future medical and health undertakings, and shoulder the mission of serving the people and the society. In order to cultivate good professional attitude, professional style and moral quality of Chinese medicine students. The subject groups take ancient Chinese medicine books such as Waike Zhengzong as the main research and arrangement objects, and fully excavate the ideological and political elements of the curriculum in the ancient books of traditional Chinese medicine, and find many elements and contents that can reflect the ideological and political elements of the curriculum. In teaching, we always adhere to the ideological and political teaching mode of “professional skills and ideological and political education” to improve the quality of teaching. Through the reform, we find that doing a good job in ideological and political courses can not only enrich the teaching content, but also entertain and educate people. The excavation of a large number of medical humanistic thoughts contained in the ancient books of traditional Chinese medicine can improve the teachers’ ideological and political ability, and improve the ideological and moral quality of students.
		2023 Vol. 20 (4): 76-80 [Abstract] ( 26 ) HTML (1 KB) PDF (755 KB) ( 43 )

	81	Exploration and practice of integrating ideological and political education into golden course standard on the teaching of traditional Chinese medicine decoction
		LI Weinan LI Yongji WAGN Yanhong WANG Rui YANG Zhixin GUAN Qingxia FENG Yufei LI Xiuyan
		DOI: 10.20047/j.issn1673-7210.2023.04.18
		Curriculum ideological and political education are innovation of educational ideas with distinctive Chinese characteristics. Integrating ideological and political education into traditional Chinese medicine education are opportunities for the reform of traditional Chinese medicine education in the new era. Due to the characteristics, it is more necessary to implement ideological and political education in traditional Chinese medicine, and the characteristics of pharmacy of Chinese materia medica curriculum determine that it contains huge ideological and political elements. How to implement the effective integrated teaching of political education and professional knowledge needs to fully integrate ideological and political education into all links of curriculum teaching in the top-level design of teaching. Taking the “decoction”cteaching in the course as an example, this paper systematically expounds the decoction teaching with the “golden course” as the standard, and how to implement the classroom teaching guided by ideological and political education in the five parts including teaching objectives, teaching content, learning situation analysis, teaching strategies and teaching evaluation. In particular, it puts forward corresponding methods on how to evaluate the teaching effect of ideological and political education, in order to provide reference for the teaching, and help the teaching reform of traditional Chinese medicine in universities.
		2023 Vol. 20 (4): 81-85 [Abstract] ( 35 ) HTML (1 KB) PDF (1793 KB) ( 102 )

	86	Mesh meta-analysis of oral traditional Chinese patent medicines and simple preparations combined with Acitretin in the treatment of psoriasis vulgaris
		ZHANG Xiu1 HAN Qingliang1 LIU Aimin2 ZHANG Buxin2
		DOI: 10.20047/j.issn1673-7210.2023.04.19
		Objective To evaluate the efficacy of oral traditional Chinese patent medicines and simple preparations combined with Acitretin in the treatment of psoriasis vulgaris (PV) by mesh meta-analysis. Methods Randomized controlled trials (RCT) of oral traditional Chinese patent medicines and simple preparations combined with Acitretin in the treatment of PV were searched from CNKI, VIP, Wanfang Data, PubMed, EMbase, and Web of Science. The retrieval time was from the inception to March 2022. The included literatures were screened, data extracted, and quality evaluated. Stata 14.0 was used for mesh meta-analysis. Results Finally, 38 RCTs were included, involving 12 traditional Chinese patent medicines and simple preparations, and 3 695 subjects were enrolled. The results of mesh meta-analysis showed that the effective rate, psoriasis area and severity index (PASI) of oral traditional Chinese patent medicines and simple preparations combined with Acitretin were better than those of Acitretin alone or combined with other adjuvant drugs (P＜0.05). In terms of effective rate, Renfu Zhiyang Capsules (OR=16.06, 95%CI: 2.79 to 92.32) combined with Acitretin had the best effect, followed by Zidan Yinxie Granules (OR=8.47, 95%CI: 1.00 to 71.94). In terms of PASI, Zidan Yinxie Granules (SMD=-2.25, 95%CI: -3.21 to -1.28) were the best, followed by Keyin Pills (SMD=-1.99, 95%CI: -2.96 to -1.01). The comparation-correction funnel plot showed that the risk of publication bias is less likely. Conclusion Oral traditional Chinese patent medicines and simple preparations combined with Acitretin has better effect in the treatment of PV, but it should still be used cautiously according to the patient’s situation in clinic.
		2023 Vol. 20 (4): 86-91 [Abstract] ( 24 ) HTML (1 KB) PDF (1602 KB) ( 40 )

	92	Clinical analysis of corneal optical density in myopia patients with different characteristics
		QIN Yanli DING Lin▲ WEI Wei Maierhaba Mijiti WANG Shaofei
		DOI: 10.20047/j.issn1673-7210.2023.04.20
		Objective To understand the corneal optical densitometry(COD) density characteristics of different myopia patients. Methods The COD of 150 patients with myopia treated in People’s Hospital of Xingjiang Uygur Autonomous Region from June 2020 to August 2021 was analyzed retrospectively. The general data, diopter, and COD of patients were counted, and the COD characteristics of different diopters, genders, and nationalities were compared and analyzed. Results The anterior corneal layer area ＞6-10 mm in low myopia group was higher than that in moderate and high myopia group, and the difference was statistically significant (P＜0.05). There was no significant difference in COD value between different genders and different corneal areas (P＞0.05). The COD of the concentric ring zone (diameter 0-2, ＞2-6, ＞6-10 mm) and the total diameter (0-12 mm) in the front, central and back layers of the Uygur were lower than that of the Han nationality; COD in the whole-layer area with diameters of 0-2, ＞6-10 mm and the total diameter of 0-12 mm were lower than those in the Han nationality, and the differences were statistically significant (P＜0.05). Conclusion The COD of different myopic people may be different, which provides a basis for further study of corneal biological characteristics of myopic people.
		2023 Vol. 20 (4): 92-95 [Abstract] ( 20 ) HTML (1 KB) PDF (429 KB) ( 161 )

	96	Effect of precision feeding training on the rehabilitation of children with severe traumatic brain injury with dysphagia
		LIU Chaoyu HU Jihong HE Jinhua DUAN Yaqin XIONG Ying RUAN Shunqiu
		DOI: 10.20047/j.issn1673-7210.2023.04.21
		Objective To study the effect of precision feeding training on the rehabilitation of children with severe traumatic brain injury with dysphagia. Methods A total of 94 children with severe traumatic brain injury with dysphagia who were treated in Rehabilitation Center, Hunan Children’s Hospital from January 2019 to April 2022 were selected and they were divided into control group (47 cases) and observation group (47 cases) by random number table method. The control group received routine rehabilitation training, while the observation group received precision feeding training. The rehabilitation effect and clinical symptoms of the two groups were compared, the standardized swallowing assessment (SSA) score and body weight were compared between the two groups before and after treatment, and the gross motor function scale (GMFM-88) was compared between the two groups before and after treatment. Results The rehabilitation effect of the observation group was better than that of the control group (P＜0.05). The recovery time of limb dysfunction, the time to complete oral feeding, the time of indwelling gastric tube and the length of hospital stay in the observation group were shorter than those in the control group (P＜0.05). After treatment, SSA score was lower and body weight was higher in both groups than before treatment, and SSA score in observation group was lower than control group, body weight was higher than control group (P＜0.05). After treatment, the scores and total scores of GMFM-88 in both groups were higher than before treatment, and the observation group was higher than the control group (P＜0.05). Conclusion Precision feeding training can improve the rehabilitation of children with severe traumatic brain injury with dysphagia. The effect is remarkable, which can promote the recovery of clinical symptoms in children, improve swallowing function, gross motor function, and quality of life, weight gain, which is worthy of promotion.
		2023 Vol. 20 (4): 96-99,107 [Abstract] ( 19 ) HTML (1 KB) PDF (676 KB) ( 39 )

	100	Effect of nape cluster needling combined with surface electromyography biofeedback on dysphagia after stroke
		TIAN Zhi WU Chang YAN Jingyi
		DOI: 10.20047/j.issn1673-7210.2023.04.22
		Objective To explore the effect of nape cluster needling combined with surface electromyography biofeedback in the treatment of dysphagia after stroke. Methods A total of 82 patients with dysphagia after stroke admitted to Nanjing Tongren Hospital from October 2019 to October 2021 were selected and divided into control group (41 cases, surface electromyography biofeedback therapy) and nape cluster needling group (41 cases, nape cluster needling combined with surface electromyography biofeedback therapy) by random number table method. The patients were treated for a total of 28 days. The Kubota drinking water test grade, swallowing function score, and quality of life score of the two groups were counted before and after treatment, and the efficacy and safety of the two groups after treatment were evaluated. Results In this study, a total of three patients withdrew, including 40 patients in control group and 39 patients in the nape cluster needling group in the final. After treatment, the Kubota drinking water test rating of the two groups was better than that before treatment, and the nape cluster needling group was better than the control group, the differences were statistically significant (P＜0.05). After treatment, the scores of standardized swallowing assessment (SSA) of two groups were lower than those before treatment, the scores of swallowing-quality of life (SWAL-QOL) of two groups were higher than those before treatment, and the scores of SSA of the nape cluster needling group were lower than the control group, and the scores of SWAL-QOL were higher than the control group, the differences were statistically significant (P＜0.05). The curative effect of the nape cluster needling group was better than that of the control group, and the difference was statistically significant (P＜0.05). There were no adverse reactions in both groups during treatment. Conclusion In the treatment of dysphagia after stroke, the combined effect of nape cluster needling and surface electromyography biofeedback is accurate, which can effectively improve the swallowing function and quality of life of patients with dysphagia after stroke, and with high safety.
		2023 Vol. 20 (4): 100-103 [Abstract] ( 26 ) HTML (1 KB) PDF (523 KB) ( 180 )

	104	Influence of different concentration of local oxygen therapy combined with vacuum sealing drainage technology on wound healing of lower extremity traumatic skin defect
		GU Cuixia CHEN Wen WANG Yuehua▲
		DOI: 10.20047/j.issn1673-7210.2023.04.23
		Objective To investigate the Influence of different concentration of local oxygen therapy combined with vacuum sealing drainage (VSD) technology on wound healing of lower extremity traumatic skin defect. Methods A total of 160 patients with lower extremity traumatic skin and soft tissue defects admitted to Suzhou Science and Technology City Hospital of Jiangsu Province from March 2020 to February 2021 were selected as the study objects. Stratified randomized method was used to divide them into groups A, B, C, and D, with 40 cases each. Group A was given VSD, group B was given 1 L/min continuous oxygen therapy combined with VSD, group C was given 3 L/min continuous oxygen therapy combined with VSD, and group D was given 5 L/min continuous oxygen therapy combined with VSD. The wound condition, wound skin grafting time, wound healing time, hospital stay time, and the occurrence of adverse reactions were compared between the four groups after seven days of treatment. Results After seven days of treatment, granulation tissue coverage in groups B, C, and D was higher than those in group A, groups C and D were higher than group B, and group D was higher than group C (P＜0.05). The wound skin grafting time, wound healing time, and hospital stay in groups B, C, and D were shorter than those in group A, groups C and D were shorter than group B (P＜0.05). There was no significant difference in the total incidence of adverse reactions among four groups (P＞0.05). Conclusion Local oxygen therapy combined with VSD can promote the growth of lower limb traumatic skin defect wounds, shorten the treatment cycle, but attention should be paid to prevent the adverse reactions that may be caused by high concentration oxygen therapy.
		2023 Vol. 20 (4): 104-107 [Abstract] ( 25 ) HTML (1 KB) PDF (572 KB) ( 29 )

	108	Analysis of influencing factors of nutritional status in hospitalized senile patients with comorbidity chronic diseases
		XIA Yinping YU Fei▲ YANG Hong ZHU Cheng LU Shuang WANG Lanlan
		DOI: 10.20047/j.issn1673-7210.2023.04.24
		Objective To explore the nutritional status in hospitalized senile patients with comorbidity chronic diseases and its influencing factors. Methods A total of 628 hospitalized patients with comorbidity chronic diseases aged ≥65 years old in the Department of Geriatrics, Tongling People’s Hospital, Anhui Province from January 2021 to March 2022 were selected for nutritional risk assessment by the nutritional risk screening scale 2002. According to the assessment results, they were divided into nutritional risk group (465 cases) and non-nutritional risk group (163 cases). The difference of clinical indexes between the two groups was compared, and the nutritional risk situation and its influencing factors were analyzed. Results The proportion of age ≥85 years old, the proportion of the number of comorbidities ＞ six kinds, the proportion of respiratory diseases, the proportion of multiple drugs ≥ five kinds, and creatinine level in nutritional risk group were all higher than those in non-nutritional risk group, and the level of body mass index (BMI), the score of activities of daily living (ADL) scale, hemoglobin, and albumin (ALB) in nutritional risk group were all lower than those in non-nutritional risk group, the differences were statistically significant (P＜0.05). The results of multivariate analysis showed that BMI (OR=0.822, 95%CI: 0.763-0.886, P＜0.001), the number of comorbidities (OR=4.810, 95%CI: 2.725-8.490, P＜0.001), the number of multiple drugs (OR=11.711, 95%CI: 5.068-27.066, P＜0.001), ADL scale score (OR=0.987, 95%CI: 0.975-0.999, P=0.037), ALB (OR=0.829, 95%CI: 0.781-0.880, P＜0.001) were independent factors of nutritional risk in hospitalized senile patients with comorbidity chronic diseases. Conclusion The incidence of nutritional risk in hospitalized senile patients with comorbidity chronic diseases is high. Therefore, we should attach great importance to the screening of nutritional risk and timely implement nutritional support for elderly patients with nutritional risk.
		2023 Vol. 20 (4): 108-111 [Abstract] ( 25 ) HTML (1 KB) PDF (492 KB) ( 187 )

	112	Effects of Dexmedetomidine on myocardial protection and serum miRNA-30a and miRNA-30b of elderly patients undergoing stage Ⅰa cervical cancer surgery
		LIANG Kaiyuan LI Zejun LI Shuizhong LIANG Dijie
		DOI: 10.20047/j.issn1673-7210.2023.04.25
		Objective To observe the effects of Dexmedetomidine (Dex) on myocardial protection as well as serum miRNA-30a and miRNA-30b of elderly patients undergoing stage Ⅰa cervical cancer surgery. Methods A total of 60 elderly patients who underwent stage Ⅰa cervical cancer surgery in Guigang People’s Hospital, Guangxi Zhuang Autonomous Region from January 2021 to March 2022 were selected as object of observation. According to the random number table method, they were divided into control group and experimental group, with 30 cases in each group. The control group was given total intravenous anesthesia by Propofol combined with Remifentanil target controlled infusion, while the experimental group was given Dex according to 0.8 μg/kg by intravenous pumping from 15 min before induction of anesthesia to 10 min after the induction, and 0.4 μg/(kg·h) was maintained until 30 min before the end of surgery, and other anesthesia methods were the same as those in the control group. The heart rate (HR) and mean arterial pressure (MAP) of two groups were compared immediately after intubation (T0), 10 min after skin incision (T1), and at the end of surgery (T2); serum creatine kinase (CK), creatine kinase MB isoenzyme (CK-MB), miR-30a, and miR-30b were compared between two groups at 15 min before surgery and 6, 12, and 24 h after surgery. Results At T1 and T2, HR and MAP in both groups were lower than those at T0, and the differences were statistically significant (P＜0.05); HR and MAP of experimental group were lower than those of control group, and the differences were statistically significant (P＜0.05). At 6, 12, and 24 h after surgery, CK, CK-MB, and miR-30a were higher than those at 15 min before surgery, while miR-30b was lower than that at 15 min before surgery, and the differences were statistically significant (P＜0.05); CK, CK-MB, miR-30a, and miR-30b of experimental group were lower than those of control group, and the differences were statistically significant (P＜0.05). Conclusion Dex has a good protective effect on the myocardium of elderly patients undergoing stage Ⅰa cervical cancer surgery, and can reduce the expression levels of serum miR-30a and miR-30b.
		2023 Vol. 20 (4): 112-115,129 [Abstract] ( 21 ) HTML (1 KB) PDF (704 KB) ( 103 )

	116	Effect of low-dose Morphine intraspinal analgesia in lower limb orthopedics department surgery in the elderly patients and its influence on the occurrence of cognition impairment
		ZHANG Jingtao1 JIA Xiaoming2 SHI Huayong1
		DOI: 10.20047/j.issn1673-7210.2023.04.26
		Objective To explore the application effect of low-dose Morphine intraspinal analgesia lower limb orthopedics department surgery in the elderly patients and its influence on the occurrence of postoperative cognitive dysfunction (POCD). Methods A total of 82 elderly patients with lower limb fracture who were admitted to the Second People’s Hospital of Zhangjiagang, Jiangsu Province from July 2020 to July 2021 were selected. They were divided into control group (41 cases) and study group (41 cases) according to the random number table method. Both groups were given combined lumbar and epidural anesthesia. After the operation, 1.5 mg Morphine was injected into the epidural space. Operation time and intraoperative and postoperative usage of Dexmedetomidine were compared between two groups; the incidence of POCD one and two weeks after operation was compared between two groups; the scores of mini-mental state examination scale (MMSE) before operation and one week after operation were compared between two groups; visual analog scale (VAS) scores were compared between two groups before operation, and 6 and 48 h after operation; the occurrence of adverse reactions in two groups was observed. Results There were no significant differences in operation time, and intraoperative and postoperative usage of Dexmedetomidine between two groups (P＞0.05). VAS scores of two groups at different time points were statistically significant (P＜0.05); 6 and 48 h after operation, VAS score of study group was lower than that of control group, and the differences were statistically significant (P＜0.05). The incidence of POCD in study group was lower than that in control group one and two weeks after operation, and the difference was statistically significant (P＜0.05). At one week after operation, MMSE scores in both groups were lower than those before operation, and those in study group were higher than those in control group, and the differences were statistically significant (P＜0.05). There was no significant difference in the total incidence of adverse reactions between two groups (P＞0.05). Conclusion The application of low-dose Morphine intraspinal analgesia in lower limb orthopedics department surgery in elderly patients can reduce the intraoperative and postoperative use of Dexmedetomidine, reduce the incidence of POCD, improve cognitive function and relieve pain.
		2023 Vol. 20 (4): 116-119 [Abstract] ( 22 ) HTML (1 KB) PDF (555 KB) ( 22 )

	120	Effect of target-oriented management of regional cerebral oxygen saturation monitoring on early cognitive function in the elderly after laparoscopic radical resection of colorectal cancer under general anesthesia
		WANG Jing WANG Jie
		DOI: 10.20047/j.issn1673-7210.2023.04.27
		Objective To explore the effect of target-oriented management of regional cerebral oxygen saturation (rScO2) monitoring on early cognitive function in the elderly after laparoscopic radical resection of colorectal cancer under general anesthesia. Methods Ninety-two elderly patients with colorectal cancer admitted to Suzhou Ninth People's Hospital, Jiangsu Province, from January 2020 to December 2021 were selected as research objects. They were divided into control group and study group, with 46 cases in each group. The control group received routine anesthesia monitoring management, and study group was combined with rScO2 monitoring on the basis of control group. The cognitive function of two groups before operation and 24 h after operation were compared; heart rate, mean arterial pressure (MAP), lactate level, and body temperature were compared before operation (T0), 30 min after anesthesia (T1) and 5 min after extubation (T2); 24 h postoperative analgesia was compared between two groups; the occurrence of perioperative adverse reactions was recorded in two groups. Results The scores of mini-mental state examination scale 24 h after operation in two groups were lower than those before operation, and study group was higher than control group, and the differences were statistically significant (P＜0.05). At T2, heart rate of study group was lower than that at T0 and T1; MAP and lactic acid were higher than those at T0 and T1, and the differences were statistically significant (P＜0.05). At T1, heart rate of study group was lower than that that at T0; lactic acid was higher than that at T0, and the differences were statistically significant (P＜0.05). At T2, heart rate and MAP of control group was lower than that at T0; lactic acid were higher than those at T0 and T1, and the differences were statistically significant (P＜0.05). At T1, heart rate of control group was lower than that at T0, MAP and lactic acid were higher than those at T0, and the differences were statistically significant (P＜0.05). At T2, lactic acid in study group was lower than that in control group, and the difference was statistically significant (P＜0.05); at T1, MAP of study group was higher than that of control group, and lactic acid was lower than that of control group, and the differences were statistically significant (P＜0.05). There was no significant difference in body temperature between two groups at different time points (P＞0.05). There was no significant difference in 24 h postoperative analgesic effect between two groups (P＞0.05). There was no significant difference in the total incidence of perioperative adverse reactions between two groups (P＞0.05). Conclusion Target-oriented management of rScO2 monitoring should be used in radical resection of colorectal cancer in elderly patients under general anesthesia to help reduce the risk of postoperative cognitive dysfunction in patients.
		2023 Vol. 20 (4): 120-123 [Abstract] ( 26 ) HTML (1 KB) PDF (554 KB) ( 37 )

	124	Summary of clinical experience of chief physician Wu Min in treating senile hypertension accompanied by insomnia
		ZHAO Yixi1 WU Min2
		DOI: 10.20047/j.issn1673-7210.2023.04.28
		This article mainly introduces the clinical experience of chief physician Min Wu in treating senile hypertension accompanied by insomnia and summarizes her academic thoughts. Hypertension and insomnia both are common diseases in the elderly. They often appear together in clinical practice and affect each other, which is easy to form a vicious circle, affecting the quality of life and psychosomatic health of elderly patients. Wu Min, chief physician, believes that the root cause of this disease lies in the two viscera of liver and kidney and is related to the heart and spleen, with the main clinical pathogenesis of the yin deficiency of liver and kidney, wind-phlegm invading upward, and deficiency of both heart and spleen. She advocates that the treatment methods of nourishing the liver and kidney, calming endogenous wind and resolving phlegm, strengthening the spleen and nourishing the heart should be applied in the clinical treatment, cautiously watching pathogenesis, and addition and subtraction with the syndrome, and take into account the pathological products of phlegm and dampness, blood stasis, qi stagnation, liver fire, and so on caused by the deficiency in origin and excess in superficiality of the elderly. The clinical curative effect is quite good.
		2023 Vol. 20 (4): 124-129 [Abstract] ( 22 ) HTML (1 KB) PDF (959 KB) ( 121 )

	130	Influence of official prescription books on the Compilation of Hui Hui Yao Fang
		MA Qin CHEN Shaohua ZHAO Kezhuo CAI Mengxin YANG Xinxin DING Kan ZHANG Lijun
		DOI: 10.20047/j.issn1673-7210.2023.04.29
		Hui Hui Yao Fang is an important literature for the study of ethnic medicine and the discovery of classic prescriptions. In terms of content arrangement, the book contains a wide range of sources and rich contents of prescriptions，and appendices such as preparations, processing, drug research and other contents. In the compilation of the first discussion and then prescription, “according to the classification of disease categories, each category is unified behind the explanation.” In the division of categories, it is the same as the medical disciplines set up by the Northern Song Dynasty Imperial Medical Bureau. This paper makes a horizontal analogy analysis between Hui Hui Yao Fang and the three official prescription books of the Song and Yuan dynasties, Taiping Huimin Heji Ju Fang, Sheng Ji Zonglu and Yu Yao Yuan Fang, and it is found that the process of compiling the book is deeply influenced by the official prescription books. Discussing the compilation process and academic characteristics of Hui Hui Yao Fang, especially the preparation of prescriptions, variety research and other materials in the book，can provide strong evidence for the current literature collation of classic prescriptions of ethnic medicine.
		2023 Vol. 20 (4): 130-135 [Abstract] ( 18 ) HTML (1 KB) PDF (1026 KB) ( 43 )

	135	Professor Sun Liping’s experience in treating infantile asthma with Shaoyao Gancao Decoction
		LI Yuhan1 SUN Liping2
		DOI: 10.20047/j.issn1673-7210.2023.04.30
		The occurrence of asthma is mainly responsible for the insufficiency of children’s lungs, spleen, and kidneys, and the liver is often superabundance, and at the same time feeling external evils. The core of its pathogenesis is latent phlegm and turbidity. Shaoyao Gancao Decoction is a famous classical formula from Zhang Zhongjing, which is highly respected by generations of physicians and is widely used in various disciplines. Professor Sun Liping believes that the treatment of phlegm must regulate qi, promote blood circulation, and sooth liver, and uses Shaoyao Gancao Decoction flexibly. In the early stage of the disease using its functions of regulating the lung, soothing the liver , and releasing exterior, in the acute attack of asthma using its functions of softing liver and camping, regulating qi and invigorating blood, in the remission stage of asthma using its functions of invigorating spleen, calming liver, and tonifying lungs, combined with different symptoms, syndrome differentiation and subtraction. This paper citing a medical record to prove its effectiveness.
		2023 Vol. 20 (4): 135-138 [Abstract] ( 21 ) HTML (1 KB) PDF (648 KB) ( 92 )

	139	Professor Liu Xinyu’s experience in treating dyslipidemia based on the theory of “phlegm turbidity”
		WANG Huihui1 LIU Xinyu2
		DOI: 10.20047/j.issn1673-7210.2023.04.31
		Dyslipidemia is a common metabolic disease in clinic. Its incidence is relatively hidden, and it is often detected by standard biochemical examination. It can cause atherosclerotic cardio cerebrovascular disease and increase the risk of tumor. The phlegm turbid theory is an important part of the etiology theory of traditional Chinese medicine, it has been playing a new and important role in the differentiation and treatment of dyslipidemia for many years. Professor Liu Xinyu has rich experience in the treatment of dyslipidemia with the combination of traditional Chinese and western medicine, he believes that the main pathogenesis of dyslipidemia is phlegm endogenous and blocking qi, according to the pathogenesis, he puts forward that according to the difference of deficiency and excess yin and yang of the lung, spleen, and kidney, from the extension of phlegm turbidity theory, he applies a variety of traditional Chinese medicine treatment methods, which reflects the characteristics of “not limited to surgery” in traditional Chinese medicine treatment. Based on the theory of “phlegm turbid” theory, professor Liu Xinyu has achieved good clinical results in the treatment of dyslipidemia.
		2023 Vol. 20 (4): 139-142 [Abstract] ( 24 ) HTML (1 KB) PDF (597 KB) ( 72 )

	143	Origin and development of fetal jaundice
		JIANG Deyou1 DUAN Fangfang2 JIANG Xicheng1 LI Wenhao1 WANG Youpeng3
		DOI: 10.20047/j.issn1673-7210.2023.04.32
		Fetal jaundice, as the most common clinical problem in the neonatal period, is mostly self-healing. However, its critical illness is life-threatening, so its prevention and treatment has been a research priority in the field of medicine. Fetal jaundice is first documented in General Treatise on Causes and Manifestations of All Diseases writed by Chao Yuanfang in Sui dynasty. Younger generation doctor summarizes that the pathological changes of the viscera are in the liver, gallbladder, spleen and stomach, and the etiology and pathogenesis include heat-dampness in pregnancy, cold-dampness encumbering spleen, liver depression and blood stasis, bile efflux, and so on. From Song dynasty to Qing dynasty, successive physicians’ perceptions of this disease has been improved, and multiple methods of diagnosis has been proposed, based on the principle of removing dampness and eliminating jaundice, such as methods of clearing heat, removing dampness and eliminating jaundice, methods of warming the middle, removing dampness and eliminating jaundice, methods of resolving stasis, dispersing accumulation and eliminating jaundice, etc. Traditional Chinese medicine has rich experience in differentiation and treatment of this disease. Considering all together, this article collates and examines accounts of relevant discourses of fetal jaundice in successive generations crucial medical books.
		2023 Vol. 20 (4): 143-146,151 [Abstract] ( 22 ) HTML (1 KB) PDF (779 KB) ( 141 )

	147	Professor Zhang Xiaotian’s experience in Herbal Paste based on “constitution differentiation-disease differentiation-syndrome differentiation”
		TANG Jiayi YU Chenghong WEI Shuoshuo ZHANG Xiaotian
		DOI: 10.20047/j.issn1673-7210.2023.04.33
		As the internal factor that determines the course of disease, constitution has an important influence on the occurrence of disease and the formation of syndrome. In clinical practice, Professor Zhang Xiaotian often takes the three-differentiation diagnosis and treatment model of “constitution differentiation-disease differentiation-syndrome differentiation” as the basis of dispensing medicine. He believes that constitution differentiation is the source, syndrome differentiation is the root and disease differentiation is the manifestation. Chinese Herbal Paste has a mild yet lasting nourishing effect and is a good preparation formulation to tonify deficiency and treat the disease. Professor Zhang Xiaotian stresses that the formula of Herbal Paste needs the combination of “constitution differentiation-disease differentiation- syndrome differentiation”, with constitution as the priority, syndrome as the secondary and disease as the last. This paper introduces professor Zhang Xiaotian’s clinical experience in using Chinese Herbal Paste to improve constitution, and analyzes a case to provide ideas for the application of Herbal Paste in clinical practice.
		2023 Vol. 20 (4): 147-151 [Abstract] ( 30 ) HTML (1 KB) PDF (759 KB) ( 34 )

	152	Experience of Professor Chen Zhaojun in the treatment of early stage knee osteoarthritis with Chenshi Suhong Decoction
		HAN Jinglu1 DENG Pin1 LIANG Huan1 SUN Xiaojie1 WANG Shulong1 HUANG Zhichao1 LI Dongxiao1 CHEN Zhaojun2
		DOI: 10.20047/j.issn1673-7210.2023.04.34
		To introduce Professor Chen Zhaojun’s clinical experience in the treatment of early stage knee osteoarthritis with Chenshi Suhong Decoction. Professor Chen believes that this disease is caused by the combination of three factors of kidney deficiency, cold dampness and blood stasis. Kidney deficiency leads to joint dystrophy, followed by internal or external attack of cold dampness, resulting in poor blood circulation and blood stasis, which blocks the channels, and further aggravates kidney deficiency and cold dampness, and so the three methods of tonifying the kidney, dispersing cold dampness and activating blood should be used as the treatment principle. Professor Chen attaches importance to the application of external treatment, and believes that external washing of traditional Chinese medicine has the dual effects of efficacy and physiotherapy, which can directly treat the disease and take effect quickly. In clinic, Chenshi Suhong Decoction is used for external washing to treat this disease, which can tonify the kidney and bones, disperse cold and dehumidification, activate blood circulation and relieve pain with the combination of various drugs, and the curative effect is reliable.
		2023 Vol. 20 (4): 152-155,171 [Abstract] ( 22 ) HTML (1 KB) PDF (805 KB) ( 65 )

	156	Clinical efficacy of syndrome differentiation acupuncture in the treatment of peripheral facial paralysis
		WANG Lei1 WANG Wengang2 WANG Yong1 BU Xiuhuan2 ZHANG Xiaoling1 ZHANG Rui1
		DOI: 10.20047/j.issn1673-7210.2023.04.35
		Objective To observe the clinical effect of syndrome differentiation acupuncture in the treatment of peripheral facial paralysis.Methods A total of 100 patients with peripheral facial paralysis treated in Qinhuangdao Hospital of Traditional Chinese Medicine from October 2020 to October 2021 were selected and they were divided into treatment group and control group according to the random number table method, with 50 cases in each group. The control group was treated with traditional acupuncture. The treatment group was treated with symptom differentiation acupuncture. The clinical efficacy was compared between two groups. The changes of House-Brackman (H-B) facial nerve function grading score , traditional Chinese medicine symptom, and sign score and facial disability index before treatment, two and four weeks of treatment in the two groups were observed. Results After four weeks of treatment, the curative effect of the treatment group was better than that of the control group (P＜0.05). H-B facial nerve function scores, traditional Chinese medicine symptom scores, somatic function and social function scores were statistically significant between the two groups at different time points (P＜0.05). The H-B facial nerve function score and somatic function score of the treatment group were higher, and traditional Chinese medicine symptom score was lower than those of the control group after two weeks and four weeks of treatment (P＜0.05). Conclusion The treatment of peripheral facial paralysis with syndrome differentiation acupuncture has a definite effect, which can significantly improve the patients’ facial symptoms, signs, functional activities, and social life quality.
		2023 Vol. 20 (4): 156-159 [Abstract] ( 20 ) HTML (1 KB) PDF (581 KB) ( 56 )

	160	Application value of white blood cell count, neutrophil to lymphocyte ratio combined with erythrocyte sedimentation rate and C-reactive protein in the diagnostic differentiation of viral pneumonia and bacterial pneumonia
		WANG Ping LUO Bing SUN Jingru
		DOI: 10.20047/j.issn1673-7210.2023.04.36
		Objective To investigate the application value of white blood cell count (WBC), neutrophil to lymphocyte ratio (NLR) combined with erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) in the diagnostic differentiation of viral pneumonia and bacterial pneumonia. Methods A total of 54 cases of viral pneumonia (viral group) and 54 cases of bacterial pneumonia (bacterial group) in Anhui No.2 Provincial People’s Hospital from February 2019 to December 2021 were selected as research objects. Blood routine (PLT), mean platelet volume (MVP), WBC, N, L, NLR, ESR, and CRP were compared between two groups, and the diagnostic efficacy of WBC, NLR combined with ESR and CRP in bacterial pneumonia were analyzed. Results WBC, N, and NLR in bacterial group were higher than those in virus group (P＜0.05); there were no significant difference in PLT, MPV, and L between two groups (P＞0.05). The levels of ESR and CRP in bacterial group were higher than those in virus group (P＜0.05). The area under the curve of combined detection was higher than that of single detection (P＜0.05). Conclusion WBC, NLR combined with ESR and CRP can accurately distinguish viral pneumonia from bacterial pneumonia, and has high application value.
		2023 Vol. 20 (4): 160-163 [Abstract] ( 19 ) HTML (1 KB) PDF (700 KB) ( 62 )

	164	Optimization strategy of inpatient income structure of a tertiary comprehensive public hospital in Anhui Province from 2017 to 2021 based on grey correlation and structural variation analysis
		WANG Yu YANG Wuyang MENG Nana ZHAO Danna
		DOI: 10.20047/j.issn1673-7210.2023.04.37
		Objective To evaluate the internal composition and changes of inpatient income of a tertiary general public hospital in Anhui Province from 2017 to 2021, so as to provide data support and reference for public hospitals in Anhui Province to further optimize the structure of medical income. Methods The inpatient income statements of a tertiary comprehensive public hospital in Anhui Province from 2017 to 2021 were extracted and evaluated by grey correlation and structural variation analysis. Results The results of grey correlation analysis showed that the correlation degree of laboratory, material, and examination income to total inpatient income was 0.901, 0.894, and 0.842, respectively. The analysis results of structural variation showed that the total structural variation of inpatient income of the hospital was 12.566%. The biggest change was in drug income (-2.911), and examination and laboratory income showed positive change. Conclusion From 2017 to 2021, the growth of drug income in inpatient income of a tertiary general public hospital in Anhui Province is controlled, but profit-driven income such as laboratory and examination continued to rise, and the income reflecting the labor value of medical staff such as treatment and surgery is low. It is suggested to further optimize and adjust the income structure, speed up the implementation process of “removing cages and replacing birds”, and ensure the healthy development of hospitals.
		2023 Vol. 20 (4): 164-167 [Abstract] ( 19 ) HTML (1 KB) PDF (540 KB) ( 40 )

	168	Research on hospital flat operation management based on data application
		YANG Yue ZHANG Yongqin
		DOI: 10.20047/j.issn1673-7210.2023.04.38
		How to use modern management concepts and methods to improve the management level of hospitals is a common problem faced by all public hospitals under the background of high quality development of public hospitals. By building an operation management platform, the research group carried out unified data governance and data mining on the data collected by various departments of the hospital, and differentiated display of information and data required by all levels on the operation management platform, and vertically compressed the original pyramid management mode into a flat management mode. The response speed and disposal efficiency of the hospital flat management mode based on data application have been significantly improved compared with before in response to emergencies, allocation of medical resources, medical quality control and other aspects, and the management cost has been compressed to a certain extent, which can meet the needs of public operation and management, and is worthy of promotion in public hospitals of the same level.
		2023 Vol. 20 (4): 168-171 [Abstract] ( 17 ) HTML (1 KB) PDF (1095 KB) ( 278 )

	172	Effect of intervention based on self-regulation learning theory on health literacy and quality of life in patients with chronic heart failure
		ZHAO Jingmin ZHANG Haiping WANG Xizhu WANG Aiying YAO Yanmin
		DOI: 10.20047/j.issn1673-7210.2023.04.39
		Objective To explore the effect of intervention based on self-regulation learning theory on health literacy and quality of life in patients with chronic heart failure. Methods A total of 120 patients with chronic heart failure who were admitted to Tangshan People’s Hospital from September 2018 to January 2021 were selected, and they were randomly divided into control group and observation group, with 60 cases in each group. The control group was given routine intervention, and the observation group was given a self-regulation learning theory on the basis of the control group. The effects of health literacy, self-burden and quality of life before and after intervention were compared between the two groups, and the rate of re-hospitalization within six months after discharge. Results After intervention, the scores of functional health literacy, interactive health literacy, and critical health literacy on the health literacy scale of the two groups were higher than before intervention, and the observation group was higher than those of the control group, the differences were statistically significant (P＜0.05); the physical burden, emotional burden, and economic burden score of the self-burden scale in the two groups were lower than those of before the intervention, and the observation group were lower than those of the control group, and the differences were statistically significant (P＜0.05); the scores of physical, emotional, and other domains in the quality of life scale of the two groups were lower than those of before the intervention, and the observation group were lower than those of the control group, and the differences were statistically significant (P＜0.05). The readmission rate within six months after discharge in the observation group was lower than that in the control group, and the difference was statistically significant (P＜0.05). Conclusion The application of the intervention based on self-regulation learning theory in patients with chronic heart failure can significantly improve the health literacy of patients, reduce the sense of self-burden, at the same time, the quality of daily life can be significantly improved, and the short-term readmission rate after discharge is lower.
		2023 Vol. 20 (4): 172-176 [Abstract] ( 20 ) HTML (1 KB) PDF (717 KB) ( 45 )

	177	Effect of water circulating thermotropic blanket on maintaining body temperature in gastrointestinal surgery
		TIAN Ting YUAN Bei WANG Fang▲
		DOI: 10.20047/j.issn1673-7210.2023.04.40
		To investigate the effect of water circulating thermotropic blanket on maintaining body temperature in gastrointestinal surgery. Methods A total of 135 patients with gastrointestinal surgery in the Surgical Operating Room, the First Affiliated Hospital of Air Force Medical University from June 2017 to August 2019 were selected, the patients were divided into control group 68 cases, and variable temperature group 67 cases by random number table method, the control group was given routine nursing, on the basis of the control group, the variable temperature group was given water circulation variable temperature blanket care, the changes of body temperature, waking time, extubation time, and total amount of infusion and irrigation were compared between the two groups. Results The overall analysis showed that there were statistically significant differences between groups, at body temperature time point comparison and interaction (P＜0.05). Further pairwise comparison showed that the intraoperative temperature of the two groups at each time point were statistically significant (P＜0.05). The body temperature of the variable temperature group was higher than that of the control group at 30, 60, 90 min and the end of operation, and the differences were statistically significant (P＜0.05). The waking time and extubation time of variable temperature group were shorter than those of control group, and the total amount of infusion and irrigation was lower than that of control group, and the differences were statistically significant (P＜0.05). Conclusion For patients undergoing gastrointestinal surgery, the combination of gel pads and water circulation temperature blanket can enhance the control effect of core body temperature stability, shorten the time of wakefulness and extubation, reduce the total amount of intraoperative infusion and irrigation, and avoid complications caused by intraoperative temperature changes on the basis of preventing pressure ulcers.
		2023 Vol. 20 (4): 177-179,184 [Abstract] ( 21 ) HTML (1 KB) PDF (594 KB) ( 37 )

	180	Effects of six Sigma lean management on growth metabolism and complications of extremely/extra-low birth weight infants
		ZHOU Hui YAN Jinfang▲ LI Shuangshuang GU Li SHEN Lihua
		DOI: 10.20047/j.issn1673-7210.2023.04.41
		Objective To investigate the effects of six Sigma lean management on growth metabolism and complications of extremely/extra-low birth weight infants. Methods A total of 84 extremely/extra-low birth weight infants admitted to the Department of Neonatology, Nantong Maternal and Child Health Hospital in Jiangsu Province from October 2019 to September 2021 were selected as the study subjects, and they were divided into control group and observation group by random number table method, with 42 cases in each group. The control group received routine care, and the observation group received six Sigma lean management on this basis. The growth metabolism and complication rates of the two groups were observed at birth, 7, 14 days after hospitalization, 14 days after discharge and 30 days after discharge. Results Overall analysis, there were statistically significant differences in body weight and oral intake calorie intergroup, time point, and interaction (P＜0.05); further pair-wise comparison, and intra-group comparison: there were statistically significant differences in body weight and oral intake calorie between the two groups at each time point (P＜0.05); comparison between groups: the body weight and the level of oral intake calorie in observation group were higher than those in control group at 7 and 14 days in hospital and 14 and 30 days after discharge (P＜0.05). There was no significant difference in the total incidence of complications between the two groups （P＞0.05）. Conclusion Six Sigma management can improve the growth metabolism of extremely/extra-low birth weight infants, and its effect on the risk of complications has been demonstrated.
		2023 Vol. 20 (4): 180-184 [Abstract] ( 13 ) HTML (1 KB) PDF (2093 KB) ( 52 )

	185	Clinical effect of standardized pain assessment intervention in patients with advanced rectal cancer pain
		NING Xiaojuan1 LIU Dangdang2▲
		DOI: 10.20047/j.issn1673-7210.2023.04.42
		[Abstract] Objective To explore the clinical effect of standardized pain assessment intervention in patients with advanced rectal cancer pain. Methods A total of sixty patients with advanced rectal cancer pain admitted to the First People’s Hospital, Hunan Province from January 2020 to January 2022 were selected. The patients were divided into reference group and intervention group by random number table method, with 30 cases in each group. The control group received routine rehabilitation nursing, and the intervention group received intervention based on standardized pain assessment. Pain relief and sleep disorder improvement were observed in the two groups. Results After intervention, the scores of the simplified McGill pain questionnaire, Hamilton anxiety scale, Hamilton depression scale in both groups were lower than before intervention, and those of the intervention group were lower than those of the reference group, the differences were statistically significant (P＜0.05); all scores of Pittsburgh sleep quality index were lower than before intervention, and those of the intervention group were lower than those of the reference group, the differences were statistically significant (P＜0.05); the total nursing satisfaction in the intervention group was better than that in the reference group, and the difference was statistically significant (P＜0.05). Conclusion Intervention based on standardized pain assessment can significantly reduce pain and improve sleep disturbance and satisfaction in patients with advanced rectal cancer.
		2023 Vol. 20 (4): 185-188,192 [Abstract] ( 17 ) HTML (1 KB) PDF (717 KB) ( 66 )

	189	Analysis of the influence of self-efficacy intervention on the compliance and satisfaction of cancer patients during PICC catheterization
		CHEN Xian1 JIANG Qingyun2 XIE Shiya3 CHEN Ting3 GONG Ling4▲
		DOI: 10.20047/j.issn1673-7210.2023.04.43
		Objective To investigate the effect of self-efficacy intervention on the compliance and satisfaction of cancer patients during Peripherally inserted central catheter (PICC) catheterization. Methods A total of 100 patients with cancer PICC catheterization admitted to Jiangning Hospital Affiliated to Nanjing Medical University from January 2020 to December 2021 were divided into observation group and control group by using random number table method, with 50 cases in each group. The control group adopted routine nursing, and the observation group adopted self-efficacy intervention mode. After a month of intervention, the total incidence of complications, compliance, nursing satisfaction, and quality of life scale (QLQ-C30) scores before and after intervention were compared between two groups. Results The catheterization compliance of the observation group was better than that of the control group(P＜0.05). The total complication rate of observation group was lower than that of control group(P＜0.05). After intervention, the scores of physical function, role function, cognitive function, emotional function, and social function in two groups were higher than those before intervention, while those of the observation group were higher than those of the control group(P＜0.05). The nursing satisfaction of the observation group was better than that of the control group(P＜0.05). Conclusion Self-efficacy intervention mode can reduce complications and improve compliance, quality of life, and nursing satisfaction in patients with tumor PICC catheterization.
		2023 Vol. 20 (4): 189-192 [Abstract] ( 22 ) HTML (1 KB) PDF (555 KB) ( 101 )

	193	Application effect of birth dance intervention in pregnant women with gestational diabetes mellitus
		CAO Qi1 ZHOU Jing2 CHENG Lin1
		DOI: 10.20047/j.issn1673-7210.2023.04.44
		Objective To explore the effect of birth dance intervention in pregnant women with gestational diabetes mellitus (GDM). Methods A total of 150 women with GDM treated in Bozhou People’s Hospital of Anhui Province from January 2021 to March 2022 were selected, according to random number table method, the patients were divided into routine group and intervention group, with 75 cases in each group. The conventional group carried out routine health care during pregnancy and perinatal period, and the intervention group, based on the conventional group, was given birth dance course intervention from 28 weeks to six weeks postpartum. Labor duration and outcome of the two groups were observed. Results The first, second, and total stages of labor in the intervention group were shorter than those in the conventional group, and the differences were statistically significant (P＜0.05); after intervention, all scores of the childbirth attitude scale in both groups were lower than before intervention, and the intervention group was lower than the conventional group, and the differences were statistically significant (P＜0.05); the 1 min Apgar score of neonates in the intervention group was higher than that in the conventional group, and the incidence of lateral perineal incision injury, and fetal distress was lower than that in the conventional group, and the differences were statistically significant (P＜0.05). Conclusion Birth dance intervention during pregnancy and delivery can help to shorten the labor process of GDM women, relieve the fear of childbirth, and improve the outcome of childbirth.
		2023 Vol. 20 (4): 193-196 [Abstract] ( 15 ) HTML (1 KB) PDF (567 KB) ( 88 )

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