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2023 Vol. 20, No. 24 Published: 2023-08-25

	4	Discussion on the medicine rules of Chinese medical masters in treating vertigo based on data mining
		ZENG Min1 HUANG Jiamin1 XIE Huanglie2 ZHOU Gulin1 HAN Pengyu2 ZHENG Chaoyang2 GUO Jianwen3
		DOI: 10.20047/j.issn1673-7210.2023.24.01
		Objective To explore the medication rules of Chinese medical masters in treating vertigo based on data mining. Methods Through the ancient and modern medical case cloud platform (v2.3.5), the qualified clinical case test prescriptions of Chinese medical masters for treating vertigo in the vertigo chapter of the Chinese Medical Master Test Case Prescription · Heart Brain Volume were screened, a database was established, and the standardized database was analyzed by means of frequency statistics, drug attribute analysis, association analysis, cluster analysis, and so on. Results A total of 53 medical records were collected, involving 70 prescriptions, and 179 Chinese materia medica were recorded. The most common sym- ptoms were dizziness, poor sleep, and weakness; the most common traditional Chinese medicine syndrome elements-nature of disease were phlegm, yang deficiency, disharmony, and yang hyperactivity; the most common pulse manifestations were stringy, thready, and slippery pulse; the most common tongue quality was red; the most common furs were thin white fur and white fur. High frequency drugs included Poria, Glycyrrhizae Radix Et Rhizoma, Atractylodis Macrocephalae Rhizoma, Pinelliae Rhizoma, and Gastrodiae Rhizoma. The drug natures were plain, warm, the drug flavours were sweet, bitter, the drugs main returned to the liver, spleen channels, the drug effect was mainly to strengthen the spleen, diuresis, and diffuse dampness. The couplet medicines were Atractylodis Macrocephalae Rhizoma-Poria, Pinelliae Rhizoma-Poria, Uncariae Ramulus Cum Uncis-Gastrodiae Rhizoma. Through cluster an- alysis, 20 kinds of drugs with high frequency could be grouped into five categories. A new prescription with Poria as the core was obtained through drug complex network analysis. Conclusion The treatment of vertigo by Chinese medical masters mainly focuses on strengthening the spleen, diuresis and diffuse dampness, supplemented by eliminating phlegm and calming endogenous wind, and coordinating yin and yang.
		2023 Vol. 20 (24): 4-8,15 [Abstract] ( 18 ) HTML (1 KB) PDF (1172 KB) ( 124 )

	9	Influence of Jiawei Danxuan Koukang on oral submucosal fibrosis and the level of autophagy in rats
		HE Jun1* ZHANG Ting1* HU Liang1 PAN Shijie1 ZOU Hong1 LIAN Kequan1 TAN Jin2 HU Zhaoyong1▲
		DOI: 10.20047/j.issn1673-7210.2023.24.02
		Objective To investigate the influence of Jiawei Danxuan Koukang on oral submucous fibrosis (OSF) and the level of autophagy in rats. Methods Twenty-four SPF male SD rats (180-200 g, 4-8 weeks old) were randomly divided into blank group, model group, and Jiawei Danxuan Koukang group, with eight rats in each group. In the model group and Jiawei Danxuan Koukang group, arecoline 0.2 ml (10 mg/ml) was injected into the bilateral buccal mucosa of the rats, once every two days, and a small toothbrush was used to brush the bilateral buccal mucosa of the rats every day for eight weeks. White lesions were observed in the buccal mucosa of the rats to determine the success of the model. After the model was successfully established, the rats in the Jiawei Danxuan Koukang group were treated with 8 ml/(kg·d) Jiawei Danxuan Koukang by gavage, and the blank group and the model group were treated with the same amount of 0.9% sodium chloride solution by gavage for four weeks. After the experiment, the bilateral buccal mucosa of the three groups were collected for hema- toxylin-eosin staining and Masson staining to observe the pathological changes and collagen fiber deposition, and the number of autophagosomes in the three groups was observed by transmission electron microscope. Immunohistochemical staining was used to detect the expression of E-cadherin and microtubule- associated protein light chain 3 (LC3) positive cells in the three groups. Western blot was used to detect the expression of E-cadherin, LC3-Ⅱ, and selective autophagy adaptor protein p62. The mRNA expression of LC3-Ⅱ and p62 was detected by RT-PCR. Results In the model group, the oral mucosal epithelium was significantly atrophed, the collagen fibers were significantly thickened and increased, the epithelial layer was thinner, and a large amount of collagen fibers were deposited in the submucosal layer. In the Jiawei Danxuan Koukang group, the oral mucosal epithelium was thicker, the collagen fibers were reduced, and the atrophy of the epithelial layer was alleviated. In model group, the number of autophagosomes was lower than that in blank group, the number of E-cadherin and LC3 positive cells were lower than those in blank group, the expression of E-cadherin and LC3-Ⅱ protein were lower than those in blank group, the expression of LC3-Ⅱ mRNA was lower than that in blank group, and the expression of p62 protein and its mRNA were higher than those in blank group (P＜0.05). In Jiawei Danxuan Koukang group, the number of autophagosomes was higher than that in model group, the expression of E-cadherin and LC3-Ⅱ protein were higher than those in model group, the expression of LC3-Ⅱ mRNA was higher than that in model group, and the expression of p62 protein and its mRNA were lower than those in model group (P＜0.05). Conclusion Jiawei Danxuan Koukang can improve OSF in rats, which may be related to the increased level of autophagy.
		2023 Vol. 20 (24): 9-15 [Abstract] ( 26 ) HTML (1 KB) PDF (1586 KB) ( 196 )

	16	Effect of three knee stitches on the morphological and behavioral changes of knee osteoarthritis model rat cartilage
		LI Renzhong1 SUN Kui2
		DOI: 10.20047/j.issn1673-7210.2023.24.03
		Objective To investigate the effect of three knee stitches on the morphological and behavioral changes of knee osteoarthritis (KOA) model rats. Methods A total of 28 male SPF SD rats (three to four weeks old, weight 180 to 220 g) were divided into blank group and model group with eight rats, acupuncture group with six rats, and western medicine group with six rats respectively by random number table method. The rat model of KOA was established by anterior cruciate ligament transection except the blank group. After five weeks of modeling, the acupuncture group received three knee stitches from the left knee joint for acupuncture treatment, once a day, and rested for five consecutive days for two days for three weeks. In the western medicine group, Diclofenac Diethylamine Latex was applied outside the affected knee. Blank group and model group were not involved. The morphological changes of cartilage after X-ray film, Lequesne MG score, Mankin’s score, cartilage, and HE staining were observed and compared. Results Compared with blank group, the left knee articular surface space narrowed, articular surface wear, and osteophyte formation were obvious in model group, articular cartilage surface defect was obvious, the number and distribution of cells were decreased, and Lequesne MG and Mankin’s scores were increased (P＜0.05). Compared with model group, Lequesne MG and Mankin’s scores in acupuncture group were decreased (P＜0.05), the surface of cartilage was slightly rough and shiny, and the number of cells was increased and arranged in a clear and orderly manner. The Lequesne MG scores in model group, acupuncture group and western medicine group after treatment were lower than those before treatment (P＜0.05). Conclusion Three knee stitches can improve the morphologic and behavioral indexes of the cartilage and protect the knee joint of KOA rats.
		2023 Vol. 20 (24): 16-19,47 [Abstract] ( 22 ) HTML (1 KB) PDF (1095 KB) ( 169 )

	20	Optimize of extraction process of Yiqi Huoxue Jiedu Mixture by multi-index comprehensive score method
		LIU Min CHEN Lifang LI Jingfeng TIAN Jiayi NIAN Honglei ZENG Weixin
		DOI: 10.20047/j.issn1673-7210.2023.24.04
		Objective To optimize the optimum extraction process of Yiqi Huoxue Jiedu Mixture. Methods The single factor test and orthogonal test were used to optimize the extraction process with the comprehensive score of the content of calycosin glucoside and salvianolic acid B, and the extraction rate as the comprehensive evaluation index, and decocting time, decocting times and water addition ratio as the factors. Results The results showed that adding ten times of water and extracting three times for one hour each time was the optimum process. Conclusion The optimized extraction process of Yiqi Huoxue Jiedu Mixture has good stability and high feasibility, and can be used for the standardized production of Yiqi Huoxue Jiedu Mixture.
		2023 Vol. 20 (24): 20-23 [Abstract] ( 21 ) HTML (1 KB) PDF (750 KB) ( 19 )

	24	Effect of Shenqi Jieyu Formula inhibiting inflammatory response in rats with postpartum depression
		LI Jingya QIU Chao ZHANG Liping
		DOI: 10.20047/j.issn1673-7210.2023.24.05
		Objective To investigate the regulating effect of Shenqi Jieyu Formula on the inflammatory response of prefrontal microglia in rats with postpartum depression (PPD). Methods Twenty four two month old SD female rats were divided into sham operation group, PPD model group, Shenqi Jieyu Formula group and Western medicine control group by random number table method, with six animals in each group; the castrated rats were injected subcutaneously with 2.5 μg estradiol and 5 mg progesterone for 16 consecutive days, after seven days, 50 μg estradiol was injected daily, and the hormone injection was stopped on day 24. The PPD rat model was established by simulating the changes of estrogen during pregnancy and postpartum. Shenqi Jieyu Formula group was given Shenqi Jieyu Formula Granules dissolved in distilled water by intragastric administration. The Western medicine control group was given Paroxetine Hydrochloride by intragastric administration. Sham operation group and PPD model group were given 2 ml distilled water by intragastric administration. After three weeks of drug intervention, the open field experiment (cross grid number and upright time) were tested, and the dorsolateral prefrontal lobes of rats were selected to detect tumor necrosis factor-α(TNF-α), cortisol (Cor), and microglial marker Iba1 antibody levels. Results The number of horizontal bars and standing times in PPD model group were lower than those in sham operation group, and the levels of TNF-α, Cor, and Iba1 were higher than those in sham operation group, and the differences were statistically significant (P＜0.05); the number of horizontal bars and standing times in Shenqi Jieyu Formula group were higher than those in PPD model group, while the levels of TNF-α, Cor, and Iba1 were lower than those in PPD model group, and the differences were statistically significant (P＜0.05). Conclusion Shenqi Jieyu Formula can improve the behavior of PPD rats, inhibit the expression of microglia in prefrontal lobe of PPD rats, and reduce the inflammatory reaction and Cor level.
		2023 Vol. 20 (24): 24-27 [Abstract] ( 19 ) HTML (1 KB) PDF (913 KB) ( 50 )

	28	Effects of Edaravone on AT1R/StAR/MR signaling pathway in myocardial remodeling mice
		XUE Yangyang1 QIN Yaoyao1 GAO Jianhui1 YUE Luanyi2 ZHANG Weiwei3 YU Shuzhen3
		DOI: 10.20047/j.issn1673-7210.2023.24.06
		Objective To explore the relationship between angiotensin Ⅱ type 1 receptor (AT1R)/ steroidogenic acute regulatory protein (StAR)/ mineralocorticoid receptor (MR) and myocardial remodeling induced by pressure overload in mice treated with Edaravone. Methods Eighteen SPF grade C57 mice, aged four weeks and weighing 22-24 g, were divided into control group, angiotensin Ⅱ group, and Edaravone group according to random number table method, with six mice in each group. The mouse myocardial remodeling model was prepared by continuous infusion of angiotensin Ⅱ 1 500 ng/(kg·min) with a subcutaneous osmotic pump for 28 days. The control group was implanted with an osmotic pump pre-filled with 0.9% sodium chloride; the edaravone group was given intraperitoneal injection of 10 mg/kg of Edaravone per day for 28 days after subcutaneous implantation of a prefilled angiotensin Ⅱ osmotic pump. After the model was successfully prepared, the hearts of mice were sacrificed and weighed to calculate the ratio of heart weight to body weight (HW/BW). Paraffin sections of myocardium were taken, and the cross-sectional area of cardiomyocytes was determined by hematoxylin-eosin staining, and collagen volume fraction was determined by Masson’s staining. The expressions of angiotensin type 1 receptor (AT1R), steroid-synthesized acute regulatory protein (StAR), salocorticoid receptor (MR), transforming growth factor-β1(TGF-β1) and α-smooth muscle actin (α-SMA) in cardiomyocytes were determined by immunohistochemical staining. Results The HW/BW ratio, MSA and CVF in angiotensin Ⅱ group were higher than those in control group, and the differences were statistically significant (P＜0.05). The HW/BW ratio, MSA, and CVF in Edaravone group were lower than those in angiotensin Ⅱ group, and the differences were statistically significant (P＜0.05). The protein expressions of AT1R, StAR, TGF-β1, α-SMA, and MR in angiotensin Ⅱ group were higher than those in control group, and the differences were statistically significant (P＜0.05). The protein expressions of AT1R, StAR, TGF-β1, α-SMA, and MR in Edaravone group were lower than those in angiotensin Ⅱ group, and the differences were statistically significant (P＜0.05). Conclusion The myocardial remodeling induced by pressure overload in mice treated with Edaravone is related to the inhibition of AT1R /StAR/MR.
		2023 Vol. 20 (24): 28-31 [Abstract] ( 26 ) HTML (1 KB) PDF (614 KB) ( 50 )

	32	Research progress in signaling pathways and transcriptional regulators related to epithelial mesenchymal transformation in pancreatic cancer and their treatment with traditional Chinese medicine
		ZU Yue WANG Ning XIN Wanling LIANG Cenyi LI Sijia CHEN Guozhong
		DOI: 10.20047/j.issn1673-7210.2023.24.07
		Pancreatic cancer (PC) is an aggressive, low early diagnosis rate, poor prognosis of malignant digestive system tumors. Experimental studies have found that epithelial mesenchymal transformation (EMT) is closely related to the pathogenesis, metastasis, and drug resistance of pancreatic cancer, which involves multiple signaling pathways and transcriptional regulatory factors. The active components of traditional Chinese medicine are closely related to EMT-related pathways and factors, thus effectively inhibiting the invasion process of tumor cells. This paper reviews the regulatory mechanism and function of EMT in pancreatic cancer and the progress of traditional Chinese medicine in the treatment of pancreatic cancer through the intervention of EMT, in order to provide a theoretical basis for the research and treatment of pancreatic cancer.
		2023 Vol. 20 (24): 32-35 [Abstract] ( 22 ) HTML (1 KB) PDF (575 KB) ( 59 )

	36	Research progress in pathogenesis of lymphocyte function-associated antigen 1/intercellular adhesion molecule in ophthalmoxerosis and immun- osuppressive drugs
		SHA Yongyi KONG Xueqing XIANG Minhong
		DOI: 10.20047/j.issn1673-7210.2023.24.08
		Lymphocyte function-associated antigen 1(LFA-1) and intercellular adhesion molecule (ICAM-1) are homologous ligands, the interaction of LFA-1/ICAM-1 is crucial for the proliferation and infiltration of immune cells. The pathogenesis of ophthalmoxerosis has afferent arm and efferent arm two pathways. The afferent arm refers to the transfer of antigen presenting cells to lymph nodes after being stimulated by the ocular surface; the efferent arm refers to the transfer of activated lymphocytes from lymph nodes to the ocular surface. LFA-1/ICAM-1 plays an important role in both the afferent and efferent arms, and is important for the diagnosis and treatment of diseases related to immune homeostasis destruction. The drugs of Lifitegrast, corticosteroids, and cyclosporine A used to ophthalmoxerosis from the perspective of immunopathology have achieved clinical results. This article reviews the pathogenesis of LFA-1/ICAM-1 in ophthalmoxerosisand the research progress of immunosuppressive drugs.
		2023 Vol. 20 (24): 36-39 [Abstract] ( 19 ) HTML (1 KB) PDF (482 KB) ( 127 )

	40	Research progress on the mechanism of psychological stress on alopecia areata based on the theory of emotional pathogenicity
		TIAN Caidie LIU Qingwu YANG Dingquan LI Shuang DUAN Xinxin
		DOI: 10.20047/j.issn1673-7210.2023.24.09
		Alopecia areata is a non-cicatricial inflammatory alopecia. Studies have shown that psychological stress is closely related to the occurrence and development of alopecia areata. There are similarities and commonalities between the theory of emotional pathogenicity in traditional Chinese medicine and psychological stress in modern medicine. The internal injury of seven emotions and the disorder of qi and blood are important factors of alopecia areata. Based on the theory of emotional pathogenicity in traditional Chinese medicine, this paper discusses the effect of psychological stress on the mechanism of alopecia areata from three aspects: neuro-endocrino-immune network disorder, oxidative stress and inflammatory response, scalp microcirculation disorder, and emphasizes the importance of individualized psychological intervention in the treatment of alopecia areata, with a view to providing new ideas for clinical diagnosis and treatment of alopecia areata.
		2023 Vol. 20 (24): 40-43 [Abstract] ( 19 ) HTML (1 KB) PDF (604 KB) ( 105 )

	44	Research progress on the production of antimicrobial peptide LL37 and its effects on inflammatory skin diseases
		DUAN Meng LEI Tiechi
		DOI: 10.20047/j.issn1673-7210.2023.24.10
		Antimicrobial peptide LL37 is the only human Cathelidin family antimicrobial peptide found in clinical practice. It can resist the invasion of pathogens, and also play a role in immune regulation and immunochemotatic to trigger or exacerbate the inflammatory process. LL37, which is highly expressed in patients with acne rosacea and psoriasis, can induce mast cells and other inflammatory cells to secrete a variety of proinflammatory cytokine and chemokines to participate in the formation of skin lesions. However, the expression of LL37 in patients with atopic dermatitis is reduced, which damages the skin barrier function and makes them more susceptible to bacterial infection. Therefore, LL37 as a target is expected to become a new idea and method for the treatment of inflammatory skin diseases such as acne rosacea. This article reviews the expression process and regulatory mechanism of LL37, and its role and related mechanisms in patients with acne rosacea, psoriasis, and atopic dermatitis.
		2023 Vol. 20 (24): 44-47 [Abstract] ( 19 ) HTML (1 KB) PDF (530 KB) ( 126 )

	48	Research progress on renal injury induced by calcineurin inhibitor
		SUN Xuan1　ZHANG Kunying2
		DOI: 10.20047/j.issn1673-7210.2023.21.11
		Calcineurin inhibitor (CNI) is a kind of widely used immunosuppressive drug. Ciclosporin A and Tacrolimus are commonly used in clinic. CNI exerts immunosuppressive effects by inhibiting T cell activation, inducing T cell apoptosis, and inhibiting the expression of various immune factors, and has significant therapeutic effects on autoimmune diseases such as systemic lupus erythematosus and membranous nephropathy. Meanwhile, CNI also has toxic side effects that can cause kidney damage. CNI can damage the glomerulus, renal microvasculature, renal tubules, and renal interstitium to varying degrees by activating the renin-angiotension-aldosterone system, destroying the balance of local vasoactive substances in the kidney, promoting oxidative stress, and other ways. Urinary retinol binding protein and other biomarkers may have some value in early detection of renal injury caused by CNI. Calcium channel blocker is considered as an effective means to alleviate CNI induced renal injury. This article aims to provide theoretical basis and prevention and treatment ideas for renal injury caused by CNI, and promote the rational and safe use of CNI in clinical practice.
		2023 Vol. 20 (24): 48-51 [Abstract] ( 28 ) HTML (1 KB) PDF (588 KB) ( 135 )

	52	Study progress of graphene family nanomaterials for medical and pharmic properties with their effects on proliferation and osteogenic differentiation of mesenchymal stem cell
		WEI Ziyuan ZHANG Xiaodong HE Jun LIU Danyang WANG Yang SHEN Lei
		DOI: 10.20047/j.issn1673-7210.2023.24.12
		In clinical, bone injury repair is a common problem, and bone tissue engineering can help overcome this problem. Graphene family nanomaterials possess potential values of inhibiting bacteria, countering inflammation and serving as bioscaffold etc. in bone tissue engineering. Although graphene family nanomaterials combined with mesenchymal stem cell can contribute to repair bone injury, they have intricate influence on proliferation and osteogenic differentiation of mesenchymal stem cell, the mechanism of which is not clear. To give full play to the application of graphene family nanomaterials in bone tissue engineering and avoid adverse reaction, in this paper, the medical and pharmic properties of graphene family nanomaterials are comprehensively analyzed, as well as the effect of them on the proliferation and osteogenic differentiation of mesenchymal stem cell and molecular mechanisms of the effects are explored in the hope of enhancing the research and application of graphene family nanomaterials in bone tissue engineering.
		2023 Vol. 20 (24): 52-55 [Abstract] ( 30 ) HTML (1 KB) PDF (578 KB) ( 220 )

	56	Research progress in the treatment of urinary incontinence after radical prostatectomy with traditional Chinese medicine
		WANG Siqi1 GAO Zhan2 WANG Zhong2 CHU Yifan1 WANG Hao1 WANG Jianwen1▲
		DOI: 10.20047/j.issn1673-7210.2023.24.13
		In order to explore the clinical value of traditional Chinese medicine in urinary incontinence after radical prostatectomy, this article reviewed the clinical experience reports in recent years. The traditional Chinese medicine treatment principle of radical prostatectomy treatment is based on “replenish kidney qi”, and the treatment methods are increasingly diversified, traditional Chinese medicine (Mantis Egg-case, Astragalus membranaceus, Codonopsis pilosula, etc.), acupuncture, moxibustion, and electroacupuncture, and other methods can effectively alleviate urinary incontinence symptoms. However, at present, the treatment method has not been standardized, and there is a lack of multi-center and large sample clinical trials, and further research and exploration are expected.
		2023 Vol. 20 (24): 56-58,68 [Abstract] ( 20 ) HTML (1 KB) PDF (651 KB) ( 108 )

	59	Construction and evaluation of a risk assessment model for asthenic syndrome in patients with malignant tumors
		WEI Jiejing1*　LU Ting2*　YING Yanping3　HUANG Biaojin3　XU Yi4
		DOI: 10.20047/j.issn1673-7210.2023.24.14
		Objective To investigate the related factors of asthenic syndrome in patients with malignant tumors, and construct a risk assessment model to predict its efficacy. Methods A total of 327 patients with malignant tumors who were hospitalized in the oncology department of a top-three hospital in Guangxi from May to August 2020 were selected. General data and laboratory indicators of the patients were collected, and grip strength was measured. The risk assessment model was determined by binary logistic regression analysis, and the model effect was tested by subject working characteristic curve. Results The incidence of asthenic syndrome in malignant tumor patients was 28.4%. There were significant differences in gender, age, grip strength, arm circumference, calf circumference, body mass index, erythrocyte, hemoglobin, total protein, albumin and prealbumin between the two groups (P＜0.05). Logistic regression results showed that gender, grip strength, arm circumference and albumin were the influencing factors of asthenic syndrome in malignant tumor patients (OR＜1, P＜0.05). H-L goodness of fit test was used to test the FMS risk prediction model (P＞0.05), and the model fit was good. When the area under ROC curve was 0.852 (95%CI: 0.807-0.897, P＜0.05), the sensitivity was 0.849, and the specificity was 0.722, the Youden index was the largest (0.572), and the prediction model score was 149 points. Conclusion The incidence of asthenic syndrome is high in patients with malignant tumors, and female patients and lower arm circumference, grip strength and albumin are risk factors for asthenic syndrome in patients with malignant tumors. 149 points is the optimal threshold value for the asthenic syndrome risk assessment model in patients with malignant tumors. The constructed asthenic syndrome risk assessment model has good diagnostic efficacy and can be verified in the next large sample.
		2023 Vol. 20 (24): 59-63 [Abstract] ( 22 ) HTML (1 KB) PDF (617 KB) ( 16 )

	64	Relationship between self-perceived burden and psychological vulnerability in elderly patients with chronic renal failure undergoing hemodialysis
		ZHANG Tingting1 XU Xianrong1▲ XU Jing1 MA Qing1 YE Yajun1 CAO Shiqi1 CHEN Lvjing1 ZUO Xiangrong2
		DOI: 10.20047/j.issn1673-7210.2023.24.15
		Objective To explore the relationship between self-perceived burden and psychological vulnerability in elderly patients with chronic renal failure sustained hemodialysis. Methods A total of 102 elderly patients with chronic renal failure who underwent maintenance hemodialysis treatment in the Renal Disease Intensive Ward of Jiangsu People’s Hospital from September 2019 to May 2022 were selected as the study objects. General data, scores of mental vulnerability questionnaire(MVQ), Connor-Dacidson psychological resilience scale (CD-RISC), and self-perceived burden scale (SPBS) were collected. The correlation of SPBS score with MVQ score and CD-RISC score were analyzed. According to the scores of SPBS, patients were divided into group A (SPBS score＜30 points) and group B (SPBS score≥30 points), and the influencing factors of patients’ self-perceived burden were analyzed. Results Among 102 elderly patients with chronic renal failure, MVQ score was (56.88±12.25) points, CD-RISC score was (35.73±9.25) points, SPBS score was (27.25±8.76) points, of which 54 cases (52.94%) in group A and 48 cases (47.06%) in group B. Pearson correlation analysis showed that SPBS score of elderly patients with chronic renal failure maintenance hemodialysis was positively correlated with MVQ score (r＞0, P＜0.05), and negatively correlated with CD-RISC score (r＜0, P＜0.05). The dialysis time of group B was longer than that of group A, the score of age, medical expense and MVQ was higher than that of group A, and the score of CD-RISC was lower than that of group A, with statistical significances (P＜0.05). Logistic regression analysis showed that dialysis time and MVQ score were risk factors for patients’ self-perceived burden (OR＞1, P＜0.05), and CD-RISC score were protective factors for patients’ self-perceived burden (OR＜1, P＜0.05). Conclusion Senile chronic renal failure patients with persistent hemodialysis generally have different degrees of self-perceived burden, and its degree is closely related to dialysis time and psychological vulnerability of patients.
		2023 Vol. 20 (24): 64-68 [Abstract] ( 26 ) HTML (1 KB) PDF (653 KB) ( 171 )

	69	Analysis of influencing factors of self-compassion in patients with depression based on structural equation
		QIAN Ping SHI Min YIN Junjun
		DOI: 10.20047/j.issn1673-7210.2023.24.16
		Objective To analyze the influencing factors of self-compassion in patients with depression based on structural equation. Methods A total of 104 patients with depression admitted to the Department of Geriatric Psychiatry of Huzhou Third People’s Hospital from July 2021 to December 2021 were selected by convenient sampling method. The Chinese version of self-compassion scale (SCS), the Toronto alexithymia scale (TAS-20), and the emotional intelligence scale were used to assess the level of self-compassion, alexithymia, and emotional intelligence of patients on admission. SCS scores of patients with depression with different data characteristics were compared, and the influencing factors of self-compassion in patients with depression were analyzed based on structural equation. Results Among 104 patients with depression, 100 patients completed the questionnaire survey. The effective rate of questionnaire recovery was 96.15%. The average score of SCS in 100 patients was (70.84±5.30) points. SCS scores of depression patients with different education levels, living conditions, alexithymia, and emotional intelligence levels were compared, and the differences were statistically significant (P＜0.05). Multivariate linear regression analysis showed that the risk factors of low self-compassion level in patients with depression were education level in junior middle school and below, living alone, and low level of emotional intelligence (P＜0.05). A structural equation model was constructed to determine the factors affecting self-compassion in patients with depression, and it was found that the relevant indicators of model fit degree met the reference standards, and the model and data fitted perfectly. Conclusion The level of self-compassion in patients with depression is at the middle level, and the level of education, living conditions and emotional intelligence can affect the level of self-compassion.
		2023 Vol. 20 (24): 69-72 [Abstract] ( 32 ) HTML (1 KB) PDF (683 KB) ( 28 )

	73	Correlation of health questionnaire-9 scores with emotional intelligence and automatic thinking in patients with depression
		ZHANG Xuan WANG Chao HUANG Hui▲
		DOI: 10.20047/j.issn1673-7210.2023.24.17
		Objective To explore the correlation of patient health questionnaire-9 (PHQ-9) with emotional intelligence and automatic thinking in patients with depression. Methods A retrospective analysis was performed on 86 patients with depression admitted to the psychological outpatient department of Huaibei People’s Hospital, Anhui Province from April to December 2021. All patients were investigated by PHQ-9, emotional intelligence scale (EIS), and automatic thinking questionnaire (ATQ). According to PHQ-9 score, depression patients were divided into mild, moderate, moderate, and severe group. EIS score and ATQ score of the four groups were compared, and the related factors affecting the severity of depression patients were analyzed by orderly logistic regression analysis. The relationship between PHQ-9 score, EIS score, and ATQ score in patients with depression were analyzed by Pearson correlation analysis. Results There were significant differences in EIS and ATQ scores among all groups (P＜0.05). EIS scores of severe, moderate, and moderate groups were lower than that of mild group, ATQ score was higher than that of mild group; the EIS scores of severe and moderate severe groups were lower than that of moderate group, and the ATQ score was higher than that of moderate group; the EIS score of severe group was lower than that of moderate to severe group, and the ATQ score was higher than that of moderate to severe group, with statistical significances (P＜0.05). Orderly logistic regression analysis showed that EIS and ATQ scores were risk factors affecting the severity of depression patients (OR[95%CI]: 3.412[3.125-3.717], 3.171[2.984-3.358], P＜0.05). The results of Pearson correlation analysis showed that there was no correlation of PHQ-9 scores with EIS and ATQ scores (P＞0.05). Conclusion Both EIS score and ATQ score are risk factors that affect the severity of depression. Therefore, interventions to improve emotional intelligence and automatic thinking can be further explored to enrich the clinical treatment of depression.
		2023 Vol. 20 (24): 73-76 [Abstract] ( 24 ) HTML (1 KB) PDF (549 KB) ( 84 )

	77	Application effect of self-made new atomizing assembly for gas cutting cannula in tracheotomy patients
		LYU Qin SUN Feng JIA Long JING Xiao▲
		DOI: 10.20047/j.issn1673-7210.2023.24.18
		Objective To investigate the application effect of self-made new atomizing assembly for gas cutting cannula in tracheotomy patients. Methods Sixty patients with percutaneous spin dilatation tracheotomy (PSDT) admitted to the Emergency Intensive Care Unit of the Third Hospital of Hebei Medical University from January 2019 to January 2022 were selected as the study objects, according to random number table method, they were divided into control group (29 cases) and experimental group (31 cases), the control group was treated with conventional atomization methods, the experimental group was treated with self-made atomizing components for gas cutting cannula, the vital signs during sputum aspiration, the effect of airway humidification and the incidence of postoperative complications were compared between the two groups. Results The vital signs of airway resistance, blood pressure and heart rate during sputum aspiration in experimental group were lower than those in control group, and blood oxygen was higher than that in control group (P＜0.05). Airway humidification effect of experimental group was better than that of control group (P＜0.05). There was no postoperative pulmonary infection in the experimental group, and the incidence of postoperative pulmonary infection in control group was 20.69%, the incidence of postoperative pulmonary infection in the experimental group was lower than that in the control group (P＜0.05). Conclusion In the process of improving PSDT treatment, self-made new atomizing assembly for gas cutting cannula was scientifically and reasonably applied to assist the intervention, it can effectively improve the clinical effect of emergency intensive care unit patients, improve physical function, and reduce postoperative pulmorary infection. It has good clinical application and popularization value.
		2023 Vol. 20 (24): 77-80 [Abstract] ( 25 ) HTML (1 KB) PDF (590 KB) ( 21 )

	81	Clinical observation of pelvic floor magnetic stimulation combined with fascia manipulation in the treatment of chronic prostatitis/chronic pelvic pain syndrome
		HUANG Ningqing1 SUN Wudong2 ZHA Jingxian2 JIN Huachao1 FANG Leiwen1 SHEN Gongda3▲
		DOI: 10.20047/j.issn1673-7210.2023.24.19
		Objective To study the clinical effect of pelvic floor magnetic stimulation combined with fascia manipulation in the treatment of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). Methods Ninety-eight patients with CP/CPPS in Zhongda Hospital Affiliated to Southeast University from July 2020 to July 2022 were selected as the research objects, and they were divided into conventional group and experimental group according to random number table method, with 49 cases in each group. The conventional group was treated with fascia manipulation, while the experimental group was treated with pelvic floor magnetic stimulation combined with fascia manipulation. After four weeks of treatment, the efficacy of two groups was evaluated, and the (National Institutes of Health chronic prostatitis symptom index, [NIH-CPSI]), urodynamics (maximum urinary flow rate [Qmax] and average urinary flow rate [Qavg]) before treatment and after four weeks of treatment were compared, and the safety during treatment was analyzed. Results The clinical effect of experimental group was better than that of conventional group (P＜0.05). After four weeks of treatment, the scores of pain and discomfort symptoms, urination symptoms, impact of symptoms on quality of life, and NIH-CPSI total score in two groups were lower than those before treatment; and those in experimental group were lower than those in conventional group (P＜0.05). After four weeks of treatment, Qmax and Qavg in two groups were higher than those before treatment, and those in experimental group were higher than those in conventional group (P＜0.05). There was no significant difference in safety between two groups (P＞0.05). Conclusion Pelvic floor magnetic stimulation combined with fascia manipulation has a significant effect on CP/CPPS, which can relieve clinical symptoms, improve urodynamics, and is safe.
		2023 Vol. 20 (24): 81-84 [Abstract] ( 23 ) HTML (1 KB) PDF (597 KB) ( 127 )

	85	Meta analysis of perioperative incidence of deep vein thrombosis in elderly patients with hip fracture
		REN Xin1 ZHANG Jiayu1 LIU Yanmei2 ZHANG Meixia3
		DOI: 10.20047/j.issn1673-7210.2023.24.20
		Objective To analyze the incidence of perioperative deep vein thrombosis (DVT) in elderly patients with hip fractures. Methods The CNKI, Wanfang Database, VIP, PubMed, Web of Science, the Cochrane Library and EMbase databases were searched, the search was conducted from January 2000 to November 2022. Results A total of 13 literatures were included, all of which were of medium and high quality and had no significant publication bias. The results were reliable. A total of 6 590 patients were included in the literature, and the incidence of DVT was 20% (95%CI:0.15 - 0.25). Subgroup analysis showed that the incidence of DVT was 16% (95%CI:0.10-0.21) in males and 18% (95%CI:0.13-0.23) in females. The incidence of DVT was 13% (95%CI:0.04-0.21) from 2005 to 2013, and 23% (95%CI:0.16-0.29) from 2014 to 2019. The incidence of DVT was 13% (95%CI:0.04-0.21) in 60-69 years, 14%(95%CI:0.07-0.21) in 70-79 years, and 14%(95%CI:0.07-0.21) in 80-89 years, the incidence of DVT in patients ≥90 years old was 22%(95%CI:0.09-0.36). Conclusion The incidence of DVT in elderly patients with hip fracture is high, and the results of meta-analysis are affected by advanced age, study type, study sample size, and case follow-up time. Therefore, medical staff should strengthen early prevention and treatment care to improve the quality of life of patients.
		2023 Vol. 20 (24): 85-88 [Abstract] ( 20 ) HTML (1 KB) PDF (624 KB) ( 42 )

	89	Effect of kinesiology tape in the treatment of early knee osteoarthritis
		WU Zhongqing1 XU Kanna2▲ SHEN Yunlong1 XU Jianxue3 LAN Jialu4
		DOI: 10.20047/j.issn1673-7210.2023.24.21
		Objective To explore the effect of kinesiology tape on the treatment of early knee osteoarthritis (KOA). Methods A total of 60 patients with early KOA who were treated in the First People’s Hospital of Huzhou from February 2021 to August 2022 were selected, Stata procedure was used to randomly assign the experimental group and the control group, with 30 cases in each group. The control group was treated with Meloxicam Tablets orally, and the experimental group was treated with kinesiology tape on the basis of the control group, with a course of seven days. After three courses of treatment, the clinical efficacy, symptom score, inflammatory factor level, and treatment safety of the two groups were evaluated. Results The clinical efficacy of the experimental group was better than that of the control group (P＜0.05). After treatment, the scores of pain, symptoms, daily activities, sports and entertainment functions, and quality of life in the two groups were lower than those before treatment, and the experimental group was lower than the control group (P＜0.05). After treatment, the levels of blood cartilage oligomeric matrix protein, interleukin-6 and hypersensitive C-reactive protein in the two groups were lower than those before treatment, and the experimental group was lower than the control group (P＜0.05). No serious adverse reactions occurred in both groups. Conclusion The kinesiology tape has a significant effect and good safety in the treatment of early KOA.
		2023 Vol. 20 (24): 89-92 [Abstract] ( 23 ) HTML (1 KB) PDF (597 KB) ( 43 )

	93	Comparison of the effect of different management methods of drainage tube in knee osteoarthritis after total knee arthroplasty#br#
		FU Dongliang HUANG Yuanxia
		DOI: 10.20047/j.issn1673-7210.2023.24.22
		Objective To investigate the effect of different management methods of drainage tube in knee osteoarthritis (KOA) after total knee arthrplasty (TKA). Methods A total of 96 patients with KOA treated with TKA admitted to the First Affiliated Hospital of Xinxiang Medical University from October 2020 to June 2022 were selected and they were divided into three groups according to random number table method, with 32 cases in each group. No drainage tube was placed during TKA in group A. In group B, the drainage tube was placed during TKA operation, and the drainage was continued after two hours of early clamping. In group C, the drainage tube was placed during the TKA operation, which was clamped intermittently for 110 minutes every two hours and opened for 10 minutes until six hours later. Preoperative and postoperative hemoglobin (Hb), hematopoiesis (HCT), pain visual analogue scale (VAS) score, circumference of affected limb, range of motion (ROM) of knee joint, postoperative drainage volume, total blood loss, and complications were recorded. Results After operation, the Hb and HCT of the three groups were lower than those before operation, and those of group B were lower than group A and group C (P＜0.05). After operation, the VAS scores of the three groups were lower than those before operation, and the circumference of the affected limb in the three groups were longer than those before operation, and the VAS scores of group B and group C were lower than those of group A, and the circumference of the affected limb of group B and group C were shorter than those of group A (P＜0.05). There was no significant difference in total blood loss among the three groups (P＞0.05); the postoperative drainage volume of group C was less than that of group B, with statistically significant (P＜0.05). There were significant differences in ROM time, between groups and interaction among the three groups (P＜0.05). Intra-group comparison: the ROM of the three groups at each time point was compared, (P＜0.05). Comparison between groups: the ROM of group B and group C on the 1st and 3rd day after operation were greater than those of group A, with statistically significant (P＜0.05). The rate of subcutaneous ecchymosis and knee joint swelling in group A were higher than those in group B and C, the differences were statistically significant (P＜0.05). Conclusion Continuous opening of the drainage tube after intermittent clamping for 6 h after TKA can improve early joint motion and reduce drainage flow, pain and complications.
		2023 Vol. 20 (24): 93-96,100 [Abstract] ( 26 ) HTML (1 KB) PDF (665 KB) ( 24 )

	97	Application of modified bone traction device in patients with lower limb bone traction
		ZHAO Linzhi XUE Yiwei LI Xia NI Xiaoyun SONG Wenwen HU Ping▲
		DOI: 10.20047/j.issn1673-7210.2023.24.23
		Objective To explore the effect of modified bone traction device on patients with lower limb fractures. Methods A total of 120 patients who underwent bone traction of lower limb in the Sixth People’s Hospital Affiliated to the Medical College of Shanghai Jiao Tong University from March to December 2021 were selected and divided into improved group and control group by random number table method, with 60 cases in each group. The control group used traditional bone traction device for bone traction, and the improved group used modified bone traction device for bone traction. Numeric rating scale (NRS) was used to evaluate the pain level before traction, loading, and unloading of traction arch, and general comfort questionnaire (GCQ) was used to evaluate the comfort of the two groups before and after traction. The operation time of bone traction device, the amount of bleeding, the incidence of pressure injury, and the satisfaction of hospitalized patients were compared between the two groups. Results The NRS scores of the two groups during loading and unloading of the traction arch were higher than those before traction, and the NRS scores of improved group were lower than those of the control group during loading and unloading of the traction arch, and the differences were statistically significant (P＜0.05). After traction, the GCQ scores of the two groups were lower than those before traction, and the GCQ scores of the improved group were higher than those of the control group, and the differences were statistically significant (P＜0.05). The operation time of the bone traction device in the improved group was shorter than that in the control group, the amount of bleeding was lower than that in the control group, and the satisfaction of hospitalized patients was better than that in the control group, and the differences were statistically significant (P＜0.05). There was no significant difference in the incidence of pressure injury between the two groups (P＞0.05). Conclusion The application of modified bone traction device in patients with lower limb bone traction can reduce pain, save operation time, and improve comfort and satisfaction.
		2023 Vol. 20 (24): 97-100 [Abstract] ( 21 ) HTML (1 KB) PDF (594 KB) ( 30 )

	101	Predictive value of serum miR-126 and miR-138 levels in children with Mycoplasma pneumoniae pneumonia
		GE Wenwen XU Ting SONG Lei▲
		DOI: 10.20047/j.issn1673-7210.2023.24.24
		Objective To study the predictive value of serum microRNA(miR)-126 and miR-138 levels in children with Mycoplasma pneumoniae pneumonia (MPP). Methods A total of 114 children with MPP from July 2020 to October 2022 in Department of Pediatrics, Nantong First People’s Hospital, Jiangsu Province were selected, and they were divided into good prognosis and poor prognosis according to the prognosis condition. The general data and clinical data including gender, age, fever time, severity of illness, blood routine indicators (white blood cell count [WBC], platelet count [PLT], erythrocyte sedimentation rate [ESR]), inflammatory factor indicators (interleukin-6 [IL-6], tumor necrosis factor-α [TNF-α], C-reactive protein [CRP]), and miR-126 and miR-138 were compared between two groups; the prognostic influencing factors of MPP children and the predictive value of miR-126 and miR-138 levels were analyzed. Results Among 114 children with MPP, 19 had poor prognosis after one course of treatment. The proportion of severe disease and the levels of WBC, PLT, IL-6, TNF-α, CRP, miR-126, and miR-138 in poor prognosis group were higher than those in good prognosis group (P＜0.05); there were no significant differences in gender, age, fever time, and ESR between two groups (P＞0.05). Severity of disease and the levels of WBC, TNF-α, CRP, miR-126, and miR-138 were the influencing factors for poor prognosis of MPP children (OR＞1, P＜0.05). The area under the curve of miR-126 and miR-138 levels predicted the prognosis of MPP children was higher than that detected by each indicator alone. Conclusion Serum miR-126 combined with miR-138 levels have a high prognostic value in MPP children.
		2023 Vol. 20 (24): 101-104 [Abstract] ( 24 ) HTML (1 KB) PDF (629 KB) ( 164 )

	105	Application of nasal continuous positive airway pressure ventilation and nasal non-invasive high-frequency oscillatory ventilation in mechanical ventilation weaning of neonatal meconium aspiration syndrome
		LIU Hong WANG Xinrui LI Shuai▲
		DOI: 10.20047/j.issn1673-7210.2023.24.25
		Objective To explore the application of nasal continuous positive airway pressure (NCPAP) and nasal non- invasive high-frequency oscillatory ventilation (NHFOV) in mechanical ventilation weaning of neonatal meconium aspiration syndrome (MAS). Methods A total of 80 newborns with MAS admitted to the Department of Neonatology, Fuyang Women’s and Children’s Hospital, Anhui Province from May 2019 to May 2022 were selected as the research objects. They were divided into NCPAP group and NHFOV group, with 40 cases in each group. MAS children of two groups were respectively given NCPAP and NHFOV respiratory support after mechanical ventilation weaning. The blood gas index (partial pressure of oxygen in arterial blood [PaO2], partial pressure of carbon dioxide in arterial blood [PaCO2], PaO2/inspired oxygen concentration [FiO2]) were compared between two groups before weaning and after weaning at 1, 12, 24 h; non-invasive breathing time, total gastrointestinal nutrition time, weaning failure rate, and complications were compared between two groups. Results PaO2, PaO2/FiO2 at different time between two groups were statistically significant (P＜0.01); PaCO2 at different time, intergroup, and interaction between two groups were statistically significant (P＜0.01). Comparison within groups: after weaning at 1, 24 h, PaO2 in both groups were higher than those before weaning; after weaning at 24 h, PaO2/FiO2 in two groups were higher than those before weaning, and the differences were statistically significant (P＜0.05). After weaning at 12, 24 h, PaCO2 of NCPAP group were lower than those before weaning; after weaning at 1, 12, 24 h, PaCO2 of NHFOV group were higher than those before weaning, and the differences were statistically significant (P＜0.05). Comparison among groups: after weaning at 1, 12, 24 h, there were no significant differences in PaO2 and PaO2/FiO2 between two groups (P＞0.05); PaCO2 in NHFOV group was lower than that in NCPAP group, and the difference was statistically significant (P＜0.05). The weaning failure rate of NHFOV group was lower than that of NCPAP group, and the difference was statistically significant (P＜0.05); there were no significant differences in non-invasive breathing time and total gastrointestinal nutrition time between two groups (P＞0.05). The total complication rate of NHFOV group was lower than that of NCPAP group, and the difference was statistically significant (P＜0.05). Conclusion Compared with NCPAP, the application of NHFOV in mechanical ventilation weaning of neonatal MAS children is more conducive to reducing PaCO2 and reducing the weaning failure rate.
		2023 Vol. 20 (24): 105-108,120 [Abstract] ( 23 ) HTML (1 KB) PDF (654 KB) ( 26 )

	109	Study on anxiety and influencing factors in patients with recurrent abortion by hysteroscopy
		DONG Yuanyuan WANG Fenfen WANG Wei
		DOI: 10.20047/j.issn1673-7210.2023.24.26
		Objective To explore the anxiety and influencing factors in patients with recurrent abortion by hysteroscopy. Methods A total of 108 cases with recurrent abortion who underwent hysteroscopy from February 2020 to February 2022 in the Second Hospital of Tianjin Medical University were selected. The Zung’s self-rating anxiety scale (SAS) was used to evaluate the anxiety of patients before hysteroscopy, according to the SAS score, the patients were divided into the anxious group (SAS score＞50 points) and the non-anxious group (SAS score≤50 points). The paper questionnaire made by the hospital was used to investigate the patients’ age, marital status, occupation, reproductive history, sexual life history, history of induced abortion, causes of abortion, attitude towards sexual behavior and induced abortion, etc., and the influencing factors of anxiety in patients with recurrent abortion by hysteroscopy were analyzed by multivariate logistic regression. Results Anxiety was present in 86 of 108 patients with recurrent abortion who underwent hysteroscopy, and SAS score was (67.42±5.33) points. There were statistically significant differences in age, marital status, location, education level, and economic income between two groups (P＜0.05); there were no significant differences in occupational status, abortion history, number of sexual partners, pregnancies number, births number, and causes of abortion between two groups (P＞0.05). Age＜25 years old (OR=1.608), unmarried (OR=2.186), economic income ≤4 000 yuan per month (OR=2.581) were the influencing factors of anxiety in patients with recurrent abortion by hysteroscopy (P＜0.05). Conclusion Age＜25 years old, unmarried, and economic income ≤4 000 yuan per month are the influencing factors of anxiety in patients with recurrent abortion by hysteroscopy. Targeted intervention for the above factors can help alleviate the anxiety of patients and improve the efficiency of hysteroscopic diagnosis and treatment.
		2023 Vol. 20 (24): 109-112 [Abstract] ( 26 ) HTML (1 KB) PDF (522 KB) ( 21 )

	113	Correlation of retinal arteriolar-to-venular diameter ratio with the severity of hypertensive disorders of pregnancy and pregnancy outcome
		ZHANG Yan ZHANG Jing XU Rui
		DOI: 10.20047/j.issn1673-7210.2023.24.27
		Objective To investigate the correlation of retinal arteriolar-to-venular diameter ratios (AVR) with the severity of hypertensive disorders of pregnancy and pregnancy outcome. Methods A total of 150 patients with hypertensive disorders of pregnancy admitted to Anhui Maternal and Child Health Hospital, Anhui Province from January 2020 to January 2022 were selected as research object. According to the severity of disease, the patients were divided into gestational hypertension group (53 cases), mild preeclampsia group (50 cases), and severe preeclampsia group (47 cases); retinal AVR was compared among three groups, and the relationship between retinal AVR and the severity of hypertensive disorders of pregnancy was analyzed. According to the pregnancy outcome, the patients were divided into good pregnancy outcome group (118 cases) and bad pregnancy outcome group (32 cases); the influencing factors of adverse pregnancy outcomes in patients with hypertensive diseases of pregnancy was analyzed. Results Retinal AVR in severe preeclampsia group was lower than that in mild preeclampsia group and gestational hypertension group; retinal AVR in mild preeclampsia group was lower than that in gestational hypertension group, and the differences were statistically significant (P＜0.05). Retinal AVR was negatively correlated with the severity of hypertensive disorders of pregnancy(r=-0.783, P＜0.05). There were significant differences in 24 h urinary protein, neutrophil count, placental growth factor, and the proportion of retinal AVR＜2/3 between good pregnancy outcome group and bad pregnancy outcome group (P＜0.05). 24 h urinary protein (OR=1.046), neutrophil count (OR=1.473), and retinal AVR ＜2/3(OR=7.272) were the risk factors for bad pregnancy outcomes in hypertensive disorders of pregnancy (P＜0.05). Conclusion Retinal AVR is associated with the severity of hypertensive disorders of pregnancy and bad pregnancy outcomes.
		2023 Vol. 20 (24): 113-116 [Abstract] ( 20 ) HTML (1 KB) PDF (547 KB) ( 27 )

	117	Effect of thermoforming time on the thickness and elastic modulus of orth-odontic thermoplastic materials
		SHI Jiayi1 ZHANG Yiwei2 XU Baohua3
		DOI: 10.20047/j.issn1673-7210.2023.24.28
		Objective To investigate the effect of thermoforming time on the thickness and elastic modulus of orthodontic thermoplastic materials. Methods Orthodontic thermoplastic materials with thicknesses of 0.380, 0.625, and 0.760 mm were selected and divided into untreated group, thermoforming 60 s group, and thermoforming 90 s group according to the thermoforming time, with ten specimens in each group of different materials. The thickness and elastic modulus of the three groups were measured by electronic vernier caliper and universal material testing machine, and the effects of different thermoforming times on the thickness and elastic modulus of the three groups were compared. Results For the thermoplastic materials of 0.380, 0.625, and 0.760 mm, the thickness of thermoforming 60 s group and thermoforming 90 s group was lower than that of the untreated group, and the thickness of thermoforming 90 s group was lower than that of thermoforming 60 s group, and the differences were statistically significant (P＜0.05). For the 0.380 mm thermoplastic material, the elastic modulus of the thermoforming 60 s group and the thermoforming 90 s group was higher than that of the untreated group, and the difference was statistically significant (P＜0.05). There was no significant difference in elastic modulus between different treatment groups of the thermoplastic materials of 0.625 and 0.760 mm (P＞0.05). Conclusion The thickness of thermoplastic material becomes thinner after thermoforming. The longer the thermoforming time, the thinner the material, and the elastic modulus of thermoplastic material of 0.380 mm increased significantly. In orthodontic clinical work, it is necessary to fully understand the properties of materials, and select appropriate materials for treatment according to the patients’ own conditions and different orthodontic treatment needs and difficulties.
		2023 Vol. 20 (24): 117-120 [Abstract] ( 14 ) HTML (1 KB) PDF (522 KB) ( 111 )

	121	Effect of retromandibular transparotid anterior masseter approach combined with absorbable bone plate in the treatment of middle and low condylar process fractures
		WANG Yunxiao1 PAN Zhiyan2 DAI Fuyue3▲ DONG Xuan4 HAN Lina5 MA Xuliang6 TIAN Rongxiang5 MENG Weidong3
		DOI: 10.20047/j.issn1673-7210.2023.24.29
		Objective To analyze the effect of retromandibular transparotid anterior masseter approach combined with absorbable bone plate in the treatment of middle and low condylar process fractures. Methods A total of 45 patients with middle and low condylar process fractures treated in Xingtai People’s Hospital of Hebei Province from January 2019 to February 2022 were selected as the research objects. According to the random number table method, they were divided into control group (23 cases) and observation group (22 cases). The control group was treated with the traditional incision around the mandibular angle combined with titanium plate nail fixation, and the observation group was treated with the retromandibular transparotid anterior masseter approach combined with absorbable bone plate. The incidence of postoperative complications and efficacy were compared between the two groups, and the oral activity of the two groups before operation and three, six months after operation were compared. Results There was no significant difference in the incidence of facial nerve injury, mouth deviation, and sialosyrinx between the two groups (P＞0.05). The incidence of postoperative incision infection in the observation group was lower than that in the control group (P＜0.05). The amplitude of mouth opening, mandibular forward movement, and mandibular lateral movement in the two groups at three and six months after operation were higher than those before operation, and those at six months after operation were higher than those at three months after operation (P＜0.05). The amplitude of mouth opening, mandibular forward movement, and mandibular lateral movement in the observation group were higher than those in the control group at three and six months after operation (P＜0.05). The clinical efficacy of the observation group was better than that of the control group (P＜0.05). Conclusion The retromandibular transparotid anterior masseter approach combined with absorbable bone plate in the treatment of middle and low condylar process fractures can improve the therapeutic effect, reduce postoperative incision infection, and improve the range of oral activity.
		2023 Vol. 20 (24): 121-124 [Abstract] ( 25 ) HTML (1 KB) PDF (615 KB) ( 151 )

	125	Effect of Sanzi Sanhuang Decoction in the treatment of combined phlegm and stasis-induced polycystic ovary syndrome
		YAN Fang1 LIU Yanxia2 ZHANG Cai3 ZHU Peixuan4 YANG Han5 QIAO Shiqing5 SU Zeqi3 WANG Ting3
		DOI: 10.20047/j.issn1673-7210.2023.24.30
		Objective To analyze the therapeutic effect of Sanzi Sanhuang Decoction on combined phlegm and stasis- induced polycystic ovary syndrome (PCOS). Methods A total of 130 patients diagnosed with PCOS with phlegm-stasis interjunction type were selected from Professor Wang Ting’s outpatient clinic of Beijing University of Chinese Medicine from January 2017 to June 2022. According to the treatment drugs, 60 cases were divided into control group and treated with Progesterone Soft Capsules; 70 cases were divided into observation group and treated with Sanzi Sanhuang Decoction, treatment period of three months. After matching with propensity score, 35 cases in control group and observation group were finally included. Menstrual status, body mass index (BMI), syndrome score of phlegm-stasis interjunction, hormone level, basal body temperature (BBT), ovarian volume and efficacy of the two groups were analyzed before and after treatment. Results After treatment, BMI in the observation group was lower than that before treatment (P < 0.01), while there was no significant difference of BMI compared with before treatment in the control group (P＞0.05). After treatment, the BMI of observation group was lower than that of control group (P＜0.01). After treatment, the scores of menstrual disorder and syndrome of phlegm, and blood stasis in the two groups were lower than those before treatment (P＜0.01), and the scores of phlegm and blood stasis syndrome in the observation group were lower than those in the control group (P＜0.05), and there was no statistical significance in the scores of menstrual disorder between the two groups (P＞0.05). After treatment, the levels of testosterone, luteinizing hormone and luteinizing hormone/follicle-stimulating hormone in the two groups were decreased compared with before treatment (P＜0.01), and the level of estradiol was increased compared with that before treatment (P＜0.01). There was no statistical significance in FSH between the two groups compared with before treatment (P＞0.05). There was no significant difference (P＞0.05). After treatment, the number of BBT biphasic body temperature cases in two groups was increased compared with before treatment (P＜0.01). There was no significant difference in the number of BBT biphasic body temperature cases between the two groups after treatment (P＞0.05). After treatment, the bilateral ovarian volume of both groups were lower than those before treatment, and the observation group was lower than the control group (P＜0.05). After treatment, the bilateral ovarian volume of both groups was lower than before treatment, and the observation group was lower than the control group (P＜0.05). There was no significant difference in clinical efficacy between the two groups (P＞0.05). Conclusion Sanzi Sanhuang Decoction can improve menstrual disorders in PCOS patients, reduce the syndrome score of phlegm, blood stasis and mutual junction, improve the status of polycystic ovaries and hormone level disorders, and promote ovulation recovery, which is clinically safe and effective. Sanzi Sanhuang Decoction is superior to Progesterone Soft Capsule in reducing patients’ BMI and improving traditional Chinese medicine syndromes.
		2023 Vol. 20 (24): 125-129,135 [Abstract] ( 44 ) HTML (1 KB) PDF (848 KB) ( 22 )

	130	Effect of Poge Jiuxin Decoction combined with β-blocker on the treatment of angina pectoris of coronary heart disease with qi stagnation and blood stasis syndrome and its anti-oxidation ability
		SHU Lili1 SONG Yingjing2 SHAO Yunfei3
		DOI: 10.20047/j.issn1673-7210.2023.24.31
		Objective To explore the effect of Poge Jiuxin Decoction combined with β-blocker on the treatment of angina pectoris of coronary heart disease with qi stagnation and blood stasis syndrome and its anti-oxidation ability. Methods A total of 168 patients with angina pectoris of coronary heart disease with qi stagnation and blood stasis syndrome were selected from the Linhai Hospital of Traditional Chinese Medicine Medical and Health Service Community of Zhejiang Province from March 2019 to March 2021, and they were divided into β-blocker group, Poge Jiuxin Decoction group, and combined drug group according to random number table method, with 56 cases in each group. Brain natriuretic peptide (BNP), cardiac troponin I(cTnI), creatine kinase-MB (CK-MB), tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), nitric oxide (NO), superoxide dismutase (SOD), malondialdehyde (MDA), glutathione peroxidase (GSH-Px), lipid hydroperoxide (LPO), traditional Chinese medicine syndrome score, and traditional Chinese medicine syndrome efficacy were observed in the three groups before treatment and two weeks after treatment. Results After treatment, the levels of BNP, cTnI, and CK-MB in the three groups were lower than before treatment, and those in the combined drug group were lower than those in the β-blocker group and the Poge Jiuxin Decoction group (P＜0.05). After treatment, the levels of TNF-α and IL-6 in the three groups were lower than before treatment, and those in the combined drug group were lower than those in the β-blocker group and the Poge Jiuxin Decoction group (P＜0.05); the level of NO in the three groups was higher than that before treatment, and that in the combined drug group was higher than that in the β-blocker group and the Poge Jiuxin Decoction group (P＜0.05). After treatment, the levels of SOD and GSH-Px in the three groups were higher than before treatment, and those in the combined drug group were higher than those in the β-blocker group and the Poge Jiuxin Decoction group (P＜0.05); the levels of MDA and LPO in the three groups were lower than before treatment, and those in the combined drug group were lower than those in the β-blocker group and the Poge Jiuxin Decoction group (P＜0.05). After treatment, the scores of angina pectoris, limb numbness, subcutaneous ecchymosis, and emotional abnormality in the three groups were lower than before treatment, and those in the combined drug group was lower than those in the β-blocker group and the Poge Jiuxin Decoction group (P＜0.05). The curative effect of traditional Chinese medicine syndrome in the combined drug group was higher than that in the β-blocker group and the Poge Jiuxin Decoction group (P＜0.05). Conclusion Qi stagnation and blood stasis syndrome patients with angina pectoris of coronary heart disease by the combination of the Poge Jiuxin Decoction and β-blocker can effectively improve the myocardial injury and inflammation of the body, enhance the antioxidant capacity, and achieve good results in clinical treatment.
		2023 Vol. 20 (24): 130-135 [Abstract] ( 32 ) HTML (1 KB) PDF (738 KB) ( 31 )

	136	Shi Suhua’s experience in treating diarrhea-predominant irritable bowel syndrome with tiaoshen anchang moxibustion
		GAO Junxia1 SHI Suhua2 LIU Huimin1 LI Zhigang3 LIN Yuting1 DONG Yifei1 YANG Ying1
		DOI: 10.20047/j.issn1673-7210.2023.23.32
		Irritable bowel syndrome (IBS) is a common gastrointestinal dysfunction, of which diarrhea type IBS(IBS-D) is the most common. Although the pathogenesis of IBS-D is related to such as spleen deficiency, dampness, and liver depression, Shi Suhua believes that chronic diarrhea will damage the kidney， no matter how the pathogenesis evolves, it will eventually develop into spleen and kidney yang deficiency. “The brain” regulates and affects gastrointestinal function, and brain-gut dysfunction runs through IBS-D. On the basis of inheriting Professor Li Zhigang’s “Tongdu Qishen” method of acupuncture treatment of mental illness, Shi Suhua proposed to treat IBS-D with tiaoshen anchang moxibustion. The moxibustion has the characteristics of large amount and special effect, ginger and moxibustion are used together, and the Ren and Du meridians are adjusted at the same time. With the help of the efficacy of meridians and acupoints and the warming effect of moxibustion and ginger, the spleen and kidney yang qi are warmed to the maximum extent, and the brain and gut function are reconciled. This article will combine’s Shi Suhua’s understanding of the etiology and pathogenesis of IBS-D, introduce the treatment of tiaoshen anchang moxibustion, and list typical cases for reference.
		2023 Vol. 20 (24): 136-139 [Abstract] ( 20 ) HTML (1 KB) PDF (627 KB) ( 30 )

	140	Professor Zhang Yu’s experience in treating nephrotic proteinuria based on “strengthening essence and reducing toxicity”
		ZHANG Qi ZHANG Yu
		DOI: 10.20047/j.issn1673-7210.2023.24.33
		Proteinuria is an important observation index for clinical treatment of chronic kidney disease patients. It can not only reflect kidney damage, but also has toxic effects on the kidney. It is the strongest predictor of end-stage kidney disease. Therefore, how to eliminate proteinuria is very important for patients with chronic kidney disease. Professor Zhang Yu believes that the production of proteinuria is based on the deficiency of spleen and kidney, the disadvantage of lung qi, and is also induced by the toxin of rheumatism and blood stasis. Therefore, this article explores and summarizes the six methods of tonifying the kidney and nourishing the yuan, strengthening the spleen and nourishing the earth, promoting lung and clearing diuresis, dispelling wind and detoxifying, resolving dampness and turbidity, and removing blood stasis and detoxifying from the perspective of “strengthening essence and reducing toxicity”. All methods should be carried out simultaneously and used alternately to achieve the goal of “strengthening the essence and supporting the root, eliminating pathogenic factors and preventing the change”, and provide a broader idea for clinical prescription of nephrotic proteinuria.
		2023 Vol. 20 (24): 140-143,173 [Abstract] ( 21 ) HTML (1 KB) PDF (888 KB) ( 8 )

	144	Experience of Bayu Wei’s osteopathy school in treating distal radius fractures
		CHEN Botao YANG Li WEI Yun KUANG Jun HOU Wen DENG Xiaobin LENG Guangxiang WEI Dehai
		DOI: 10.20047/j.issn1673-7210.2023.24.34
		Bayu Wei’s osteopathy school in the treatment of distal radius fractures, which advocates “conservative treatment without surgery, minimally invasive treatment without opening”. The conservative treatment is based on the principle of “viewing the skin and feeling the bone, observing the shape and dividing the age, apply their respective methods”. The core reduction technology is “traction and pulls on the radius, abduction and supination of the wrist, compression of the fracture end and turning to the opposite side, separation of the radius and ulna”. Internal medication, two-stage syndrome differentiation, tonifying the kidney and promoting blood circulation throughout the entire process. Apply “Yizhu Powder” externally to the affected area, use a new limited contact pressure splint to fix the broken end to reduce swelling, and cooperate with elbow flexion suspension to reduce displacement. Combining muscle management with martial arts to accelerate the recovery of injured limbs. This diagnosis and treatment scheme improves the effect of conservative management for distal radius fracture, and enriches the theory of traditional Chinese medicine for fracture treatment.
		2023 Vol. 20 (24): 144-147 [Abstract] ( 20 ) HTML (1 KB) PDF (1024 KB) ( 45 )

	148	Clinical effect of Qiyang Capsules on impotence in diabetes mellitus with kidney deficiency and blood stasis type
		DING Qian1 ZHAO Feng2 LIU Qian1 ZHANG Qian2 YANG Xiaoli1 XU Yangtao3
		DOI: 10.20047/j.issn1673-7210.2023.24.35
		Objective To study the clinical effect of Qiyang Capsules on impotence in diabetes mellitus with kidney deficiency and blood stasis type. Methods A total of 160 patients with kidney deficiency and blood stasis type diabetes mellitus impotence treated in the Second Central Hospital of Baoding, Hebei Province from March 2017 to June 2019 were selected and divided into control group and observation group by coin toss method. The control group (71 cases) received routine hypoglycemic treatment and low-dose phosphodiesterase type 5 inhibitor, and the observation group (89 cases) were treated with Qiyang Capsules, for one month. The clinical efficacy, international index of erectile function-5 (IIEF-5) score, modified sexual life quality questionnaire-quality of life (mSLQQ-QoL) score, erectile hardness (EHS) grading , sex hormone levels (testosterone [T], testosterone estradiol [E2]) before and after treatment and adverse reactions of the two groups were compared. Results The clinical efficacy of the observation group was better than that of the control group, and the difference was statistically significant (P＜0.05). After treatment, IIEF-5 and mSLQQ-QoL scores in two groups were higher than before treatment, and those in the observation group were higher than those in the control group, the differences were statistically significant (P＜0.05). After treatment, the EHS grading of the two groups was better than that before treatment, and that of the observation group was better than that of the control group, the differences were statistically significant (P＜0.05). After treatment, T level in the two groups was higher than before treatment, and that in the observation group was higher than that in the control group, E2 level in the two groups was lower than before treatment, and that in the observation group was lower than that in the control group, the differences were statistically significant (P＜0.05). There was no significant difference in the total incidence of adverse reactions between the two groups (P＞0.05). Conclusion Qiyang Capsules can effectively improve erectile function and hardness, improve sexual life quality, and regulate sex hormone level in treatment of kidney deficiency and blood stasis type diabetes mellitus impotence, without significant adverse reactions.
		2023 Vol. 20 (24): 148-151 [Abstract] ( 26 ) HTML (1 KB) PDF (596 KB) ( 131 )

	152	Application of health belief-based rehabilitation training in patients with femoral neck fracture after traffic accident
		ZHOU Xun1 HOU Xiaoling2▲
		DOI: 10.20047/j.issn1673-7210.2023.24.36
		Objective To analyze the application effect of rehabilitation training based on health belief in patients with femoral neck fracture after traffic accident. Methods The study was a prospective randomized controlled trial involving 100 patients with femoral neck fracture who underwent artificial hip replacement at West China Hospital of Sichuan University from September 2021 to May 2022. Randomized number table method was used to divide the control group (50 cases) and the experimental group (50 cases). The control group was given routine rehabilitation training intervention, and the experimental group was given rehabilitation training intervention based on health belief. Both groups were interfered for four weeks. Harris hip function score, rehabilitation nursing activities of daily living (RNADL) rating scale and, self-care agency scale-revised(ASAS-R-C) scores were recorded before and after intervention. The nursing compliance and complication rate were compared between the two groups. Results After six months of follow-up, Harris hip function score, and RNADL score in both groups were higher than those before intervention, and those of the experimental group were higher than those of the control group, and the differences were statistically significant (P＜0.05). After four weeks of intervention, the ASAS-R-C scores of the two groups were higher than those before intervention, and those of the experimental group were higher than those of the control group, and the differences were statistically significant (P＜0.05). At discharge, the nursing compliance of the experimental group was higher than that of the control group (P＜0.05). There was no significant difference in the incidence of complications between the two groups (P＞0.05). Conclusion Rehabilitation training based on health belief can accelerate hip function recovery, improve self-care ability, activities of daily living ability, and nursing compliance of patients after femur neck fracture caused by car accident.
		2023 Vol. 20 (24): 152-156 [Abstract] ( 21 ) HTML (1 KB) PDF (707 KB) ( 183 )

	157	Application of internal jugular vein catheter fixation device in hemodialysis patients with uremia
		YANG Na1 ZHOU Xiaoguang2▲ CHEN Yuqian1 HUANG Lifeng1
		DOI: 10.20047/j.issn1673-7210.2023.24.37
		Objective To investigate the application effect of internal jugular vein catheter fixation device in hemodialysis patients with uremia. Methods Forty-one hemodialysis uremic patients with conventional internal jugular vein catheter fixation from May 2020 to May 2021 in Beijing Chao-yang Hospital, Capital Medical University were selected as the control group, and 45 hemodialysis uremic patients with self-installed internal jugular vein catheter fixation device from June 2021 to June 2022 were selected as the experimental group using convenience sampling method. The differences in puncture point bleeding, catheter displacement, dressing crimping, frequency of change, length of change, and patient satisfaction with hemodialysis uremic patients were compared between the two groups. Results The incidence of puncture point bleeding and catheter displacement in the experimental group were lower than those in the control group, the frequency of catheter fixation device change was less than that in the control group, and the length of change was shorter than that in the control group, and the differences were statistically significant (P＜0.05). There was no statistically significant difference in the rate of dressing crimping between the two groups (P＞0.05). Neck movement, comfort, convenience, and overall satisfaction after catheter fixation were better in the experimental group than those in the control group, and the differences were statistically significant (P＜0.05). Conclusion The application of internal jugular vein catheter fixation device can improve the safety of reinforced catheter fixation, reduce the impact of displacement on the puncture point and improve the satisfaction of clinical use.
		2023 Vol. 20 (24): 157-160 [Abstract] ( 25 ) HTML (1 KB) PDF (641 KB) ( 85 )

	161	Application effect of nursing intervention strategy based on KANO model in chemotherapy of children with malignant tumors
		YU Pingping SUN Huazhong LIU Yan CUI Bingbing GAO Qun
		DOI: 10.20047/j.issn1673-7210.2023.24.38
		Objective To study the application effect of nursing intervention strategy based on KANO model in chemotherapy of children with malignant tumors. Methods A total of 81 children with malignant tumors and their parents (one parent for each child) hospitalized in Anhui Children’s Hospital from January 2020 to June 2022 were selected for this study. The children and their parents were divided into control group (40 pairs) and observation group (41 pairs) according to random number table method. The control group was given conventional chemotherapy nursing after chemotherapy, and the observation group was given nursing intervention strategy based on KANO model. Chemotherapy compliance, parents’ satisfaction, and the incidence of major complications after chemotherapy were observed and compared between the two groups. Results After intervention, the chemotherapy compliance scores of the two groups were higher than those before intervention, and those of observation group were higher than those in the control group, and the differences were statistically significant (P＜0.05). After intervention, the parents’ satisfaction in the observation group was better than that in the control group, and the difference was statistically significant (P＜0.05). After intervention, the total incidence of major complications after chemotherapy in the observation group was lower than that in the control group, and the difference was statistically significant (P＜0.05). Conclusion The nursing intervention strategy based on KANO model has a good application effect in children with malignant tumors undergoing chemotherapy, which can effectively reduce the incidence of major complications after chemotherapy, improve the compliance of children with chemotherapy, and improve the satisfaction of parents, which is worthy of promotion and application.
		2023 Vol. 20 (24): 161-164 [Abstract] ( 23 ) HTML (1 KB) PDF (585 KB) ( 181 )

	165	Application effect of multidisciplinary collaboration and hierarchical collaboration combined with target temperature intervention in patients with cardiac arrest
		YE Yanan1 LIU Xingxing1 ZHU Tingting1 ZHANG Gongping2
		DOI: 10.20047/j.issn1673-7210.2023.24.39
		Objective To explore the application effect of multidisciplinary collaboration and hierarchical collaboration combined with target temperature intervention in patients with cardiac arrest. Methods A total of 80 patients with cardiac arrest admitted to Lishui Central Hospital of Zhejiang Province from January 2021 to January 2022 were collected and divided into observation group and control group according to different nursing measures, with 40 cases in each group. The observation group was treated with multidisciplinary collaboration and hierarchical collaboration combined with target temperature intervention, and the control group was treated with multidisciplinary collaboration and hierarchical collaboration intervention. The intervention time of the two groups were both for one month. The emergency situation of the two groups were observed. The bispectral index (BIS) and neurological function were compared between the two groups at 24 h, 72 h, one week, two weeks after admission, and the occurrence of adverse reactions in the two groups was recorded. Results The pain relief time of the observation group was shorter than that of the control group, and the heart recovery rate and survival rate were higher than those of the control group, and the differences were statistically significant (P＜0.05). The time to reach the target temperature, the time of initial treatment, the total time of examination, the time of emergency department, and the length of hospital stay in the observation group were shorter than those in the control group, and the differences were statistically significant (P＜0.05). The BIS of the two groups at 72 h, one week, two weeks after admission were lower than those at 24 h after admission, and the National Institutes of Health stroke scale (NIHSS) scores were higher than those at 24 h after admission, and the differences were statistically significant (P＜0.05). The BIS of the observation group at 72 h, one week, two weeks after admission were higher than those of the control group at the same time points, and the NIHSS scores were lower than those of the control group at the same time points, and the differences were statistically significant (P＜0.05). The total incidence of adverse reactions in the observation group was lower than that in the control group, and the difference was statistically significant (P＜0.05). Conclusion Multidisciplinary collaboration and hierarchical collaboration combines with target temperature intervention can shorten the time for patients to reach the target temperature, improve the success rate of first aid, promote the recovery of neurological function, and reduce the incidence of adverse conditions.
		2023 Vol. 20 (24): 165-168 [Abstract] ( 19 ) HTML (1 KB) PDF (588 KB) ( 124 )

	169	Application of nursing intervention based on Neuman theory combined with levator ani muscle exercise in patients with prostate cancer after operation
		SONG Silin YANG Xilan▲
		DOI: 10.20047/j.issn1673-7210.2023.24.40
		Objective To explore the application of nursing intervention based on Neuman theory combined with levator ani muscle exercise in patients with prostate cancer after operation. Methods A total of 120 patients with prostate cancer who planned to undergo radical prostatectomy in Nanjing First Hospital from April 2020 to July 2022 were selected as the study objects. According to the random envelope method, the patients were divided into control group and experimental group, with 60 cases in each group. The control group was given conventional nursing combined with levator ani muscle exercise intervention, and the experimental group was given nursing intervention based on Neuman theory. Urodynamic indexes, functional assessment of cancer therapy-prostate (FACT-P), self-rating anxiety scale (SAS), and self-rating depression scale (SDS) scores were compared between the two groups, and the incidence of postoperative complications was compared between the two groups. Results After three months of follow-up, the maximum closed urethral pressure of both groups was higher than that at discharge, and the experimental group was higher than that of the control group (P＜0.05). The maximum urinary flow and maximum bladder capacity of both groups were higher than those at discharge, and the experimental group was higher than that of the control group (P＜0.05). After three months of follow-up, the FACT-P scores of both groups were higher than those at discharge, and the experimental group was higher than that of the control group (P＜0.05). At discharge, the scores of SAS and SDS in both groups were lower than those of before intervention, and the experimental group was lower than that of the control group (P＜0.05). The total incidence of urinary incontinence in experimental group was lower than that in control group (P＜0.05). Conclusion Nursing intervention based on Neuman theory combined with levator ani muscle exercise can improve the urodynamic indicators and emotional state of patients after radical prostatectomy, improve their quality of life, and reduce the incidence of postoperative urinary incontinence.
		2023 Vol. 20 (24): 169-173 [Abstract] ( 18 ) HTML (1 KB) PDF (790 KB) ( 34 )

	174	Effect of whole-process follow-up empowerment education on patients with laryngeal cancer after partial laryngectomy
		YAN Meiju1 MA Xiao1 LI Ning2 ZHANG Ling1▲
		DOI: 10.20047/j.issn1673-7210.2023.24.41
		Objective To explore the effect of whole-process follow-up empowerment education on patients with laryngeal cancer after partial laryngectomy. Methods A total of 121 patients with laryngeal cancer who underwent partial laryngectomy at the Second Affiliated Hospital of Air Force Medical University of Chinese People’s Liberation Army from March 2017 to March 2022 were selected, according to random number table method, they were divided into control group (60 cases) and observation group (61 cases). The control group received routine nursing, and the observation group received whole-process follow-up empowerment education based on routine nursing. The compliance, improvement of swallowing function, nutritional status, and quality of life of the two groups were compared. Results The compliance of swallowing function training in the observation group was better than that in the control group (P＜0.05). At three months after operation, the scores of lowland drinking water test and diet assessment scale scores in both groups were lower than one day before discharge, and the observation group was lower than the control group (P＜0.05). At three months after surgery, the patient-generated subjective global assessment (PG-SGA) score of both groups was lower than one day after surgery, the European Organization for Research and Treatment of Cancer head and neck tumor specific quality of life questionnaire (EORTC QOL-H&N35) score was higher than one day after surgery, and the PG-SGA score of the observation group was lower than that of the control group, EORTC QOL-H&N35 score was higher than that of control group (P＜0.05). Conclusion The application of whole-process follow-up empowerment education in laryngeal cancer patients with partial laryngectomy can effectively improve their compliance with swallowing function training, and further improve their swallowing function, nutritional status, and quality of life.
		2023 Vol. 20 (24): 174-177 [Abstract] ( 19 ) HTML (1 KB) PDF (602 KB) ( 25 )

	178	Effect of mind mapping-based health education on the cooperation and image quality of patients with fluorescein fundus angiography
		ZHAO Nan LI Yu▲ LI Haijing WU Yaqiong
		DOI: 10.20047/j.issn1673-7210.2023.24.42
		Objective To investigate the effect of mind mapping-based health education on the cooperation and image quality of patients with fluorescein fundus angiography(FFA). Methods A total of 110 patients who underwent FFA in the Department of Ophthalmology of Xuanwu Hospital of Capital Medical University were selected, and they were divided into control group and observation group according to random number table method from January to May 2022, with 55 patients in each group. The conventional health education was used in the control group, and the mind mapping health education mode was used in the observation group on the basis of the control group, the degree of knowledge, cooperation, and eye image quality of the two groups were compared. Results After intervention, the scores of body preparation, eye preparation, medication guidance, diet guidance, body position guidance, and knowledge mastery of precautions in both groups were higher than those before intervention, and the observation group was higher than those of the control group, and the differences were statistically significant (P＜0.05); the degree of cooperation of the observation group was higher than that of the control group, and the difference was statistically significant (P＜0.05); the eye image quality of the observation group was better than that of the control group, and the difference was statistically significant (P＜0.05). Conclusion Mind mapping-based health education given to patients during FFA is able to effectively help patients improve their perception of relevant knowledge, which in turn improving their cooperation in examination, and contributing to better fundus image quality in the examination.
		2023 Vol. 20 (24): 178-181 [Abstract] ( 24 ) HTML (1 KB) PDF (811 KB) ( 206 )

	182	Effect of individualized nutrition intervention and dietary guidance based on scored patient-generated subjective global assessment on patients with newly diagnosed type 2 diabetes mellitus
		ZHANG Ling CHEN Shuxia ZHOU Yusen MU Jinglan
		DOI: 10.20047/j.issn1673-7210.2023.24.43
		Objective To explore the effect of individualized nutrition intervention and dietary guidance based on scored patient-generated subjective global assessment (PG-SGA) in patients with newly diagnosed type 2 diabetes. Methods A total of 80 patients with newly diagnosed type 2 diabetes were selected from Bozhou People’s Hospital in Anhui Province from January 2020 to November 2021 for this study. They were divided into observation group and control group according to random number table method, with 40 cases in each group. The control group received routine intervention, and the observation group received individualized nutrition intervention and dietary guidance based on PG-SGA. The intervention lasted for three months. The score of healthy eating behavior, fasting blood glucose (FBG), 2 h postprandial blood glucose (2hPG), glycated hemoglobin (HbA1c) and the compliance of patients with dietary behavior were compared between the two groups before and after the intervention. Results After intervention, the scores of healthy eating behavior in both groups were lower than those before intervention, and the score of healthy eating behavior in observation group was higher than that in control group, and the differences were statistically significant (P＜0.05). After intervention, FBG, 2hPG, and HbA1c in both groups were lower than those before intervention, while FBG, 2hPG, and HbA1c in the observation group were lower than those in the control group, and the differences were statistically significant (P＜0.05). The total compliance rate of dietary behavior in observation group was higher than that in control group, and the difference was statistically significant (P＜0.05). Conclusion Individualized nutrition intervention and dietary guidance based on PG-SGA have obvious effects in the intervention of patients with newly diagnosed type 2 diabetes, and are worthy of clinical promotion.
		2023 Vol. 20 (24): 182-185 [Abstract] ( 28 ) HTML (1 KB) PDF (573 KB) ( 55 )

	186	SWOT analysis and strategies on the cultivation of traditional Chinese medicine translation talents in China
		YAN Li1 YU Ruohan2
		DOI: 10.20047/j.issn1673-7210.2023.24.44
		Traditional Chinese medicine translation talents are the core element of traditional Chinese medicine translation and dissemination activities, but the current talent cultivation and reserve are not directly proportional to the scale and speed of China’s traditional Chinese medicine “going global”. This article uses the SWOT analysis tool to explore the internal and external factors that affect the cultivation of Chinese medicine translation talents in China, and propose to serve the needs of the country and increase the intensity and scale of talent cultivation, to optimize the curriculum system and reform the talent cultivation mode of integrating industry and education, to promote the development of interdisciplinary Chinese medicine translation according to the characteristics of the universities, and to form a two-way interactive and collaborative linkage effect by professional integration and employment. This provides a reference for the systematic cultivation and large-scale reserve of traditional Chinese medicine translation talents.
		2023 Vol. 20 (24): 186-189 [Abstract] ( 29 ) HTML (1 KB) PDF (594 KB) ( 53 )

	190	Dilemma and solution of Yi nationality targeted medical students’ training under the background of healthy China
		YUE Yuan1 LI Huiyuan2 LI Baoguo2
		DOI: 10.20047/j.issn1673-7210.2023.24.45
		Against the backdrop of the construction of a healthy China, Sichuan Province firmly implements the decisions and deployments of the Party Central Committee, prioritizes the development of ensuring the health of the entire Sichuan people, and implements the great health and great health strategy throughout the province. The strategic implementation focuses on the western ethnic areas, with the main measures being to increase support for the construction of grassroots medical and health talent teams in ethnic areas, and to implement the targeted medical student training project in ethnic areas. The training of Yi nationality targeted medical students is an important component of this project, and the training task is undertaken by medical colleges within the province. Chengdu Medical College, as one of the colleges and universities undertaking the training task, has conducted targeted training for fresh graduates of rural medicine majors from Liangshan, Ganzi, and Aba Health Schools since 2012 to 2020. During the training, it is found that there are mainly problems such as lack of learning motivation for Yi nationality targeted medical students, poor connection between theoretical courses and clinical practice, and difficulty in improving academic qualifications. Based on this, future training should focus on the following three aspects: firstly, combining the characteristics of Yi nationality targeted medical students with individualized teaching; secondly, efforts to improve the professional skills of Yi nationality targeted medical students; thirdly, expanding the education improvement path for Yi nationality targeted medical students.
		2023 Vol. 20 (24): 190-193 [Abstract] ( 20 ) HTML (1 KB) PDF (657 KB) ( 55 )

	194	Research on the construction path of innovation and entrepreneurship guidance service system in higher colleges and universities of traditional Chinese medicine under the background of “the 14th Five-Year Plan”
		LIU Zhenqiang1 WANG Qifan2
		DOI: 10.20047/j.issn1673-7210.2023.24.46
		Based on the background of “the 14th Five-Year Plan” strategic planning for the development of Chinese medicine, this paper clarifies the practical significance of the construction of the guidance service system for innovation and entrepreneurship in higher traditional Chinese medicine institutions under the new situation, analyzes the existing problems of the current guidance service system for innovation and entrepreneurship in higher colleges and universities of traditional Chinese medicine. The practical requirements for the construction of the innovation and entrepreneurship guidance service system in higher colleges and universities of traditional Chinese medicine under the new situation are proposed by making good use of the main teaching channels of innovation and entrepreneurship courses, optimizing the practice links of innovation and entrepreneurship, and strengthening the support and guarantee for innovation and entrepreneurship. This provides a reference basis for cultivating innovative Chinese medicine talents and promoting the reform of higher education in traditional Chinese medicine.
		2023 Vol. 20 (24): 194-封三 [Abstract] ( 25 ) HTML (1 KB) PDF (603 KB) ( 219 )

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