胰腺癌中上皮间质转化的相关信号通路和转录调节因子及其中药治疗的研究进展

doi:10.20047/j.issn1673-7210.2023.24.07

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Abstract Pancreatic cancer (PC) is an aggressive, low early diagnosis rate, poor prognosis of malignant digestive system tumors. Experimental studies have found that epithelial mesenchymal transformation (EMT) is closely related to the pathogenesis, metastasis, and drug resistance of pancreatic cancer, which involves multiple signaling pathways and transcriptional regulatory factors. The active components of traditional Chinese medicine are closely related to EMT-related pathways and factors, thus effectively inhibiting the invasion process of tumor cells. This paper reviews the regulatory mechanism and function of EMT in pancreatic cancer and the progress of traditional Chinese medicine in the treatment of pancreatic cancer through the intervention of EMT, in order to provide a theoretical basis for the research and treatment of pancreatic cancer.

Key words： Pancreatic cancer Epithelial-mesenchymal transitions Traditional Chinese medicine Literature review

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	ZU Yue WANG Ning XIN Wanling LIANG Cenyi LI Sijia CHEN Guozhong

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ZU Yue WANG Ning XIN Wanling LIANG Cenyi LI Sijia CHEN Guozhong. Research progress in signaling pathways and transcriptional regulators related to epithelial mesenchymal transformation in pancreatic cancer and their treatment with traditional Chinese medicine[J]. 中国医药导报, 2023, 20(24): 32-35.

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https://www.yiyaodaobao.com.cn/EN/10.20047/j.issn1673-7210.2023.24.07 OR https://www.yiyaodaobao.com.cn/EN/Y2023/V20/I24/32

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