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2021 Vol. 18, No. 28 Published: 2021-10-05

	4	Development problems and countermeasures analysis of rural revitalization strategy driven by Chinese medicine industry in Hunan Province
		LIU Zhengyu NIU Yuxia LIU Jinhong LI Ling XIA Xinbin
		Industrial revitalization is the primary task of rural revitalization strategy, and it is the key that realizes agriculture, countryside, farmer modernization, the traditional Chinese medicine industry is one of the important characteristic industries to boost the rural revitalization strategy. Hunan Province is in the process of implementing the decision and deployment of the CPC Central Committee on consolidating the achievements of poverty alleviation and implementing the rural vitalization strategy, it can give full play to the advantages of Hunan as a Province with large traditional Chinese medicine resources, the development of the traditional Chinese medicine industry will empower rural revitalization. Therefore, this paper analyzes the hunan provincial government attaches great importance to the Chinese medicine industry, based on the abundant production factors of traditional Chinese medicine industry and the expanding demand of traditional Chinese medicine industry, the problems existing in the development of traditional Chinese medicine industry in Hunan Province were analyzed from the aspects of finance, planting, output value and scientific and technological competitiveness, and it is also suggested that the development of traditional Chinese medicine industry should be considered in the formulation of the party’s major policies and policies, the financial support for traditional Chinese medicine industry should be increased, the platform carrier for the development of traditional Chinese medicine industry should be constructed, and the foundation should be consolidated, focus on building leading traditional Chinese medicine enterprises and other development countermeasures.
		2021 Vol. 18 (28): 4-7,23 [Abstract] ( 95 ) HTML (1 KB) PDF (818 KB) ( 155 )

	8	Expression of Egl nine homolog 3 in breast cancer and its effect on malignant phenotype of breast cancer cells
		WANG Yang1 ZHAO Zitong2 SONG Yongmei2 ZHANG Bailin1
		Objective To investigate the expression and function of the Egl nine homolog 3 (EGLN3) in breast cancer. Methods The expression of EGLN3 in 1085 cases of breast cancer tissues and 291 cases of normal tissues from the TCGA and GTEx databases was analyzed by using GEPIA website. A total of 52 cases of breast cancer tissues and adjacent tissues were collected in Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College from January 2010 to December 2017. The EGLN3 mRNA expression in breast cancer tissues was detected by real-time PCR. EGLN3 protein expression in normal breast epithelial cell (MCF-10A) and 11 cell lines of breast cancer (ZR-75-1, SK-BR-3, MDA-MB-453, BT474, MCF-7, T47D, MDA-MB-231, CAL-51, HS578T, MDA-MB-468, HCC1937) were detected by Western blot. The effect of transfection siRNA knockdown EGLN3 on proliferation, clonal formation, invasion and migration of breast cancer cells were detected by xCELLigence RTCA MP system, clonal formation assay and Transwell assay, respectively. Results The expression of EGLN3 mRNA in breast cancer tissues was higher than that in normal tissues， and the difference was statistically significant (P < 0.05). The expression of EGLN3 mRNA in breast cancer tissues was higher than that in adjacent tissues, and the difference was highly statistically significant (P < 0.01). EGLN3 protein was highly expressed in breast cancer cells MDA-MB-231, CAL-51, MDA-MB-468, and HCC1937, but not in normal breast epithelial cells and other breast cancer cells. After transfection with siRNA knockdown EGLN3, the proliferation, clonal formation, invasion and migration of breast cancer cells were decreased. Conclusion EGLN3 expression may be related to the occurrence and development of breast cancer, and down-regulation of EGLN3 can inhibit the malignant phenotype of breast cancer cells, but its mechanism needs further study.
		2021 Vol. 18 (28): 8-12,34 [Abstract] ( 131 ) HTML (1 KB) PDF (981 KB) ( 88 )

	13	Analysis of key genes and potential drugs in acute myocardial infarction combined with chronic obstructive pulmonary disease based on bioinformatics
		JIANG Chenyang LI Shuo CHAO Xiaoying ZHONG Guoqiang
		Objective To provide a new bioinformatics basis for the diagnosis and treatment of the disease, we analyzed the key genes and potential drugs of acute myocardial infarction (AMI) complicated with chronic obstructive pulmonary disease (COPD) based on bioinformatics. Methods Three data sets containing AMI and COPD microarray information were downloaded from the GEO database and differentially expressed genes (DEG) were screened. GO function annotation, KEGG pathway enrichment analysis, and Metascape enrichment analysis were performed on the differentially expressed genes shared by the two diseases. Then a protein protein interaction (PPI) network was constructed to identify key genes involved in the occurrence and development of diseases. Finally, the drug-drug gene interaction database was used to find potential therapeutic drugs. Results After integrating the three data sets of AMI and COPD, 61 DEGs were obtained. The results of GO function annotation showed that they were mainly involved in inflammation, carbohydrate and glucocorticoid receptor binding. Mostly located in the outer membrane of organelles and the inner cavity of particles. KEGG and Metascape enrich the pathways such as immune, inflammation, and apoptosis. Eight key genes identified by the PPI network, a total of 74 potentially related therapeutic drugs were screened. Tuberculin, tomalizumab, resveratrol caproic acid, tasquinide, and pannimod were highly associated with diseases. Conclusion The identified genes and pathways may be potential therapeutic targets for AMI combined with COPD, and provide a new basis for the molecular mechanism of the disease.
		2021 Vol. 18 (28): 13-17 [Abstract] ( 149 ) HTML (1 KB) PDF (1278 KB) ( 114 )

	18	Discussion on the mechanism of action of Jinfu’an Decoction in the treatment of non-small cell lung cancer based on network pharmacology and molecular docking technology
		CHEN Ming1 SUN Zhe1 WANG Sisi1 WANG Wenping1 HUANG Zhongming2 PENG Huiting2 LIN Xiaotong2 CAO Yang1

		2021 Vol. 18 (28): 18-23 [Abstract] ( 96 ) HTML (1 KB) PDF (1772 KB) ( 201 )

	24	Protective effect of glycyrrhizic acid on sepsis induced acute kidney injury in rats and its possible mechanism
		ZHOU Haiyin1 LONG Caixia1 LUO Lan1 CHEN Yanying1 LIU Pingping1 XIAO Zhenghui1 ZHANG Shuju2
		Objective To study the protective effect and possible mechanism of glycyrrhizic acid (GA) on sepsis induced acute kidney injury in rats. Methods SD rats were divided into sham operation group, GA 50 mg/kg group, sepsis group, sepsis +GA 25 mg/kg group, and sepsis +GA 50 mg/kg group, with six rats in each group. Sepsis group rats were intraperitoneally injected with lipopolysaccharide (LPS) at 5 mg/kg. HBZY-1 cells were divided into control group, 100 μmol/L GA group, LPS group, LPS+GA 50 μmol/L group and LPS+GA 100 μmol/L group. LPS group was cultured with 10 μg/ml LPS for 24 h to establish nephritis model. Histopathological changes of kidney were observed by HE staining; the contents of tumor necrosis factor-α (TNF-α), monocyte chemotactic protein-1 (MCP-1), intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) in renal tissue were determined by enzyme-linked immunosorbent assay; HBZY-1 cells apoptosis, inflammation and oxidative stress related protein expression were analyzed by Western blot. Results The renal interstitium, glomerulus and tubules of sepsis rats were infiltrated with inflammatory cells, and some renal tubules were swollen and vacuolar degeneration. The above pathological changes in the renal tissues of sepsis rats were significantly relieved after GA treatment. The expression levels of TNF-α, ICAM-1 and VCAM-1 in rat renal tissues of sepsis+GA 25 mg/kg group and sepsis+GA 50 mg/kg group were lower than those of sepsis group (P < 0.05). The level of MCP-1 in rat renal tissue of sepsis+GA 50 mg/kg group was lower than that of sepsis group (P < 0.05). The expression levels of cyclooxygenase-2 and nuclear factor-κB protein in HBZY-1 cells in LPS+50 μmol/L and LPS+100 μmol/L GA groups were lower than those in LPS group (P < 0.05 or P < 0.01), the inducible nitric oxide synthase level in LPS+GA 100 μmol/L group was lower than that in LPS group (P < 0.01). The relative expression of Bcl-2/Bax in HBZY-1 cells in LPS+GA 100 μmol/L group was higher than that in LPS group (P < 0.01). The expression of cleaved Caspase-3 protein in HBZY-1 cells in LPS+GA 50 μmol/L and LPS+GA 100 μmol/L groups were lower than those in LPS group (P < 0.01). The heme oxygenase-1 protein expression level in LPS+GA 50 μmol/L group and LPS+GA 100 μmol/L group were higher than those in LPS group (P < 0.01). The expression level of p-ERK protein in LPS+GA 100 μmol/L group was higher than that in LPS group (P < 0.01). Conclusion GA has a protective effect on acute kidney injury induced by sepsis in rats, and its mechanism may be related to inhibiting apoptosis, oxidative stress and inflammatory response.
		2021 Vol. 18 (28): 24-28,39 [Abstract] ( 423 ) HTML (1 KB) PDF (1217 KB) ( 47 )

	29	Exploring the mechanism of action of eucommia ulmoides-epimedium-gusuobu prescription in the treatment of osteoporosis based on network pharmacology and molecular docking
		WU Peng* LI Sha* SHI Xiaoqing LIAO Taiyang CHEN Jupeng
		Objective To investigate the mechanism of action of eucommia ulmoides-epimedium-rhizoma drynariae (DYG) in the treatment of osteoporosis (OP) by network pharmacology and molecular docking. Methods The main active components of DYG and their targets were screened by oral bioavailability and drug similarity in Chinese medicine system pharmacological database GeneCard, OMIM, PharmGkb, Therapeutic Targets and DrugBank databases were used to build target databases for OP. The common targets for durgs and diseases were constructed using Venn diagrams. Cytoscape software was used to build a visual traffic network of “DYG active ingredient-action target-osteoporosis”. Protein protein interaction network was constructed by STRING database. GO functional enrichment analysis and KEGG signal pathway analysis were performed on the core targets. Molecular docking was conducted between the active ingredients of DYG and the screened core targets through Discovery Studio 2016. Results At otal of 38 active components and 168 related targets were screened from DYG, there were 4547 targets associated with OP, 11 active ingredients-key targets of the disease were obtained, the GO enrichment analysis showed that the biological processes were mainly involved in phosphatase binding, amide binding, nuclear receptor activity, etc. KEGG pathway analysis showed that the potential signaling pathways mainly included AGE-RAGE, apoptosis, IL-17, TNF, and other signaling pathways. Molecular docking showed that DYG active components could be well docked with IL-6, EGF, JUN, MAPK8, CXCL8, MMP9, MAPK1 and IL-1β. Conclusion DYG can treat OP with multiple components, pathways and targets. This study provides a theoretical basis and a new direction for the treatment of osteoporosis by DYG.
		2021 Vol. 18 (28): 29-34 [Abstract] ( 147 ) HTML (1 KB) PDF (2352 KB) ( 113 )

	35	Molecular mechanism of Mahuang Fuzi Xixin Decoction in the treatment of asthma based on network pharmacology
		JIA Menghuan1 ZHANG Cairong2 FENG Longfei3
		Objective To explore the key active components and molecular mechanism of Mahuang Fuzi Xixin Decoction in the treatment of asthma based on network pharmacology. Methods The active components and drug targets of Mahuang Fuzi Xixin Decoction were searched and screened in traditional Chinese medicine systems pharmacology database and analysis platform, and the target was standardized by Uniprot database. The genes related to asthma were retrieved by using comparative toxicogenomics database. The therapeutic target was obtained by intersection of drug target and disease target by Venn diagram. The therapeutic targets were imported into the STRING database for analysis, and the proteinprotein interaction network was constructed. The target greater than the average value of degree, betweenness centrality, and closeness centrality was the key target. Finally, GO enrichment analysis and KEGG signaling pathway analysis were carried out for the key targets. Results The results of literature review and analysis showed that there were five main active ingredients in Mahuang Fuzi Xixin Decoction: quercetin, luteolin, kaempferol, β-sitosterol, and naringenin. The key targets include tumor necrosis factor (TNF), interleukin-6, TP53, etc. KEGG enrichment analysis showed that Mahuang Fuzi Xixin Decoction involved 15 major signaling pathways including TNF signaling pathway and Toll-like receptor signaling pathway. GO enrichment showed that there were 124 biological processes, 24 molecular functions, and 12 cell compositions in the treatment of asthma by Mahuang Fuzi Xixin Decoction. Conclusion Mahuang Fuzi Xixin Decoction in the treatment of asthma may have multi-channel, multi-target, multi-component joint effect, the treatment of asthma provides the basis of bioinformatics.
		2021 Vol. 18 (28): 35-39 [Abstract] ( 130 ) HTML (1 KB) PDF (1199 KB) ( 80 )

	40	Effect of Buyang Huanwu Decoction on hemorheology and platelet aggregation in hyperlipidemia rats
		BIAN Jingqi ZHANG Yukun FENG Yuenan NIU Wenying
		Objective To study the effect of Buyang Huanwu Decoction on hemorheology and platelet aggregation in hyperlipidemia rats. Methods Forty 2.5-month-old clean-grade male SD rats weighing about 240 g were selected. Ten rats were randomly fed ordinary diet as blank group, and the other 40 rats were fed high-fat diet for four weeks to create hyperlipidemia model. According to random number table method, they were divided into Buyang Huanwu Decoction high-dose group (14.0 g/kg), Buyang Huanwu Decoction low-dose group (3.5 g/kg), Simvastatin control group (0.004 g/kg) and model group, with ten rats in each group. Except blank group and model group were given distilled water, the other groups were given relevant drugs by intragastric administration for four weeks. The plasma total cholesterol, triglyceride, low density lipoprotein cholesterin, whole blood viscosity, plasma viscosity, 6-keto-prostaglandin F1α, thromboxane B2, thromboxane A2, prostacyclin, cyclic adenosine monophosphate and cyclic guanosine monophosphate contents were determined. Results Compared with blank group, whole blood viscosity, plasma viscosity, plasma total cholesterol, triglyceride, low density lipoprotein cholesterin, thromboxane B2, thromboxane A2, cyclic guanosine monophosphate were significantly increased, 6-keto-prostaglandin F1α and prostacyclin were significantly decreased in model group, the differences were statistically significant (P ＜ 0.05). Compared with model group, the whole blood viscosity and plasma viscosity in Buyang Huanwu Decoction high-dose and low-dose groups were significantly decreased, and the plasma total cholesterol, triglyceride and low density lipoprotein cholesterin were significantly decreased, the plasma levels of thromboxane B2, thromboxane A2 and cyclic guanosine monophosphate in Buyang Huanwu Decoction high-dose and low-dose groups were significantly decreased, while the level of prostaglandin was significantly increased, with statistical significance (P ＜ 0.05). Compared with model group, the cyclic adenosine monophosphate in Buyang Huanwu Decoction low-dose group was significantly decreased, with statistical significance (P ＜ 0.05). Conclusion Buyang Huanwu Decoction can significantly improve the hemorheology and dyslipidemia of hyperlipidemia model rats, and can inhibit platelet aggregation, at the same time, it can prevent and treat the formation and development of hyperlipidemia and thrombosis.
		2021 Vol. 18 (28): 40-43,47 [Abstract] ( 105 ) HTML (1 KB) PDF (559 KB) ( 82 )

	44	Effect of Shenqi Xiaozhi Recipe on appetite of ICR obese mice
		LIU Yingke1 REN Xinxin1 LI Tianxin2 YANG Ye1 WANG Qiuli1 ZHANG Chen1
		Objective To study the effect of Shenqi Xiaozhi Recipe on the appetite of ICR obese mice. Methods A total of 50 male SPF grade ICR mice (eight weeks old) were took, all weighing (250±10) g, and random number table method was used to select eight mice as normal group. The normal group was given normal feed, and the others were given high-fat feeding. After 12 weeks of administration, 10% of the body weight greater than the normal group indicated that the model was successful. In order of numbering, eight animals were selected as the model group and eight as the drug group. The drug group was given Shenqi Xiaozhi Recipe by gavage intervention, and the other two groups were given distilled water gavage intervention, the administration volume was 0.2 ml/10 g. All groups were given intragastric administration for 12 weeks, once a day. At 6 and 12 weeks of administration, the body fat, weight and food intake of three groups were measured. Results Compared with the model group, the food intake of the drug group at 6 and 12 weeks of administration decreased significantly, and the differences were statistically significant (P < 0.05). Compared with the normal group, the net weight gain of the model group increased significantly after 12 weeks of administration, and the difference was statistically significant (P < 0.05); compared with the model group, the net weight gain of the drug group at 6 and 12 weeks of administration were significantly reduced, and the differences were statistically significant (P < 0.05). There was a statistically significant difference in the net weight gain between the model group and the administration group after 12 weeks of administration and 6 weeks of administration (P ＜ 0.05). Compared with the normal group, the body fat ratio of the model group increased at 6 and 12 weeks after administration, and the differences were statistically significant (P < 0.05). After 12 weeks of administration, the body fat ratio of the model group was higher than that of six weeks of administration, and the difference was statistically significant (P <0.05). Conclusion Shenqi Xiaozhi Recipe can reduce the appetite of ICR obese mice and improve body weight to a certain extent.
		2021 Vol. 18 (28): 44-47 [Abstract] ( 76 ) HTML (1 KB) PDF (537 KB) ( 44 )

	48	Screening and gene mutation analysis of glucose-6-phosphate dehydroge deficiency in neonates in Foshan, Guangdong Province
		YUAN Weixi SHAO Qiaoyi ZHANG Pengyi LIU Liya LIU Haiping
		Objective To investigate the incidence of glucose-6-phosphate dehydrogenase deficiency and its gene mutation in the neonates in Foshan, Guangdong Province. Methods A total of 156 227 newborns born in various midwifery institutions under the jurisdiction of Newborn Disease Screening Center of Foshan Women and Children Hospital from January 2019 to December 2020, were selected as the study subjects. Fluorescence analysis was used to screen for glucose-6-phosphate dehydrogenase deficiency in neonatal dry blood spots samples. For those who were positive in the initial screening, their peripheral blood was collected for glucose-6-phosphate dehydrogenase deficiency gene test with the consent of the guardian. Results There were 6361 positive cases of glucose-6-phosphate dehydrogenase deficiency in the initial screening, and the positive rate was 4.07%. The positive rate of male was higher than that of female, and the difference was statistically significant (P ＜ 0.05). A total of 2556 cases of positive glucose-6-phosphate dehydrogenase deficiency were recalled in the initial screening, and the recall success rate was 40.18%. Among them, 575 cases agreed to glucose-6-phosphate dehydrogenase deficiency gene testing, and 559 cases were detected with gene mutation, and the gene coincidence rate was 97.22%. A total of ten mutation types were detected, and the top three mutation rates were c.1376G＞T (31.07%), c.1388G＞A (30.74%), and c.95A＞G (17.36%), accounting for 79.17% of the total mutations. The detection rate of c.517T＞C mutation was 1.49%. Conclusion C.1376G＞T, c.1388G＞A, c.95A＞G are the most common mutations of glucose-6-phosphate dehydrogenase deficiency gene in neonates in Foshan, Guangdong Province. In addition, there are carriers of c.517T＞C mutation in this region. In order to reduce missed diagnosis, this site should be included in the range of genetic testing.
		2021 Vol. 18 (28): 48-50,62 [Abstract] ( 51 ) HTML (1 KB) PDF (863 KB) ( 99 )

	51	Research situation of the syndrome differentiation of micro-indexes of chronic heart failure
		ZHONG Senjie LI Jing LI Lin HU Siyuan YANG Meng ZHANG Qian XIONG Xiajun HU Zhixi
		The typical external symptoms and signs of chronic heart failure appear relatively late, while the traditional four-diagnostic method failed to go deep into the micro level, which seriously restricts the development of syndrome differentiation. Micro-indexes obtained by modern detecting techniques can enrich the visual observation content of external images, and make up for the limitations of the traditional four-diagnostic method, thereby gradually becoming beneficial complements to the syndrome differentiation of chronic heart failure. This paper summarizes the research situation of micro-indexes such as cardiac function classification and related indicators, natriuretic peptides secreted by the heart, biological markers and other micro indexes in the syndrome differentiation of chronic heart failure, analyzes the correlation between different micro-indexes and the evolution of chronic heart failure syndromes, discusses the diagnostic value and limitations of each micro-indexes, and discussse the limitations of single index and the lack of specificity of some indexes at present, and puts forward some development ideas, such as introducing the concept of weight quantification, combined application of multiple indexes and the aid of system biology, in order to provide new ideas for the objectification of chronic heart failure syndrome differentiation.
		2021 Vol. 18 (28): 51-55 [Abstract] ( 78 ) HTML (1 KB) PDF (495 KB) ( 66 )

	56	Research progress of virtual reality / augmented reality technology characteristics and its enlightenment in nursing education
		ZHENG Xiaoying ZHANG Xiaoyu
		Advances in new technologies such as virtual reality (VR) and augmented reality (AR) are driving the growth of online forms of nursing education. By describing the characteristics of VR/AR technology, this paper discusses the VR/AR technology that can be applied in nursing education, expounds the problems encountered in the application of it in the process of education in the past, as well as the advantages of VR/AR technology in the application of nursing education in the future, which provides a basis for the application of VR/AR technology in the process of nursing education and teaching.
		2021 Vol. 18 (28): 56-58,70 [Abstract] ( 106 ) HTML (1 KB) PDF (977 KB) ( 229 )

	59	Research progress on the risk predictors of perineal injury in parturients delivered vaginally
		ZHANG Han DUAN Xia
		Perineal injury will have serious adverse effects on the short-term and long-term prognosis of vaginal delivery women. It can also cause complications such as perineal pain, fecal incontinence, and pelvic organ prolapse. It has become an important factor that endangers the healthy life of postpartum women. This article focuses on the current research status of the perineal injury risk predictors of vaginal delivery women at home and abroad, and reviews the perineal injury risk predictors from the fetus, mother, medical and social levels. This article aims to explore the specific predictors of perineal injury in women in my country, and establish a set of clinical perineal injury risk prediction model suitable for our country’s national conditions to provide reference.
		2021 Vol. 18 (28): 59-62 [Abstract] ( 132 ) HTML (1 KB) PDF (521 KB) ( 37 )

	63	Medical and industrial integration of biomedical engineering case teaching practice
		WEI Guohui MIN Weiwei LI Liping
		The introductim to biomedical engineering course is theoretical and abstract to understand, so the traditional teaching method cannot meet the requirements of modern medicine. According to the problems in the teaching process, the teaching team combined the latest scientific research results to analyze the necessity of teaching reform of biomedical engineering course, and proposed some teaching reform schemes, such as case-based teaching design based on scientific research backfeeding teaching, personalized teaching design through heuristic teaching and teaching evaluation design. Case-based teaching can not only enhance the freshmen’s understanding of their major and cultivate their interest in learning, but also cultivate their innovative spirit and ability to discover, analyze and solve problems.
		2021 Vol. 18 (28): 63-66 [Abstract] ( 103 ) HTML (1 KB) PDF (748 KB) ( 135 )

	67	Preliminary exploration of applying digital technology to case analysis teaching in education of orthodontic graduate students
		ZHANG Hao1 GAO Jie1 QIU Jun2 QIN Wen1
		Objective To investigate the effect of applying 3D digital technology in the case analysis teaching for department of orthodontic graduate students. Methods A total of 40 third-grade postgraduate students in Stomatology Hospital of Fourth Military Medical University from October 2018 to December 2019 were selected as the research subjects. A total of 20 graduate students of 2017 class were selected as the experimental group, and 20 graduate students of the 2017 class were selected as the control group. Seminar case analysis teaching was used in the control group, while Seminar combined with 3D digital technology was used in the experimental group. The teaching effect was evaluated by questionnaire and the orthodontic test. Results The teaching methods of the experimental group were better evaluated, and the case analysis part and total scores of the experimental group were higher than those of the control group, with statisticahtly significance (P ＜ 0.05). Conclusion The application of 3D digital technology in Seminar case analysis teaching can significantly improve the teaching effect of orthodontic case analysis, stimulate students’ interest in learning and spirit of exploration, and improve students’ comprehensive ability of clinical diagnosis and analysis, which is worthy of further promotion and exploration.
		2021 Vol. 18 (28): 67-70 [Abstract] ( 80 ) HTML (1 KB) PDF (754 KB) ( 76 )

	71	Application of case-based teaching method of syndrome differentiation of six meridians in standardized training of professional postgraduates in the hospital affiliated to university of traditional Chinese medicine
		HUANG Minghan1 CHEN Qin2 HE Youcheng1 SUN Yueming1 LIN Ping1,3
		Syndrome differentiation of the six meridians in Treatise on Cold-induced Diseases is an important part of syndrome differentiation and treatment of traditional Chinese medicine. The cultivation of traditional Chinese medicine professional postgraduates’ thinking ability based on syndrome differentiation of the six meridians should focus on reviewing the provisions, establishing a framework, understanding the original purpose, differentiating disease-syndrome-symptom, combining clinical symptoms and so on. Case-based teaching is a teaching method to internalize or explicit theoretical knowledge through clinical cases. Case-based teaching method of syndrome differentiation of the six meridians focuses on the combination of diseases and symptoms, addition and subtraction of syndromes, disassembly of prescriptions and medicines, interpretation of provisions and differentiation of disease-syndrome-symptom, which are explained comprehensively and deeply through the analysis of clinical cases. This teaching method helps to form a virtuous circle of teaching and learning, and substantially improves the clinical ability of professional postgraduates in traditional Chinese medicine, so it is worth popularizing and applying in the hospital affiliated to university of traditional Chinese medicine.
		2021 Vol. 18 (28): 71-74 [Abstract] ( 62 ) HTML (1 KB) PDF (700 KB) ( 150 )

	75	Exploration on the cultivation of new engineering talents facing the 100 billion industrial chain of local biomedicine according to the concept of outcomes-based education
		HONG Xuan1,2 ZHANG Yanan2 WANG Ying2 LUO Haohong2 CHEN Zhongwei2
		Xiamen Medical College, as a local application-oriented college, takes the initiative to connect with the local biomedical industry chain industry, aiming at cultivating high-quality applied talents for the local biomedical industry. According to the concept of outcomes-based education, a new engineering talent training mode of “production, learning, research, technology and innovation” in biopharmaceutical has been constructed by Xiamen Medical College, which is closely integrated with industry, diligent and independent learning, early start of scientific research, multi skill training and wide innovation cultivation. The advantageous resources of universities, governments, enterprises and scientific research institutes have been integrated and the innovation and entrepreneurship base of biomedical practice education has been established, which promots the comprehensive reform of professional training program, curriculum system, scientific research ability training, practice, innovation and entrepreneurship platform, and realizs the cultivation of high-quality application-oriented new engineering talents.
		2021 Vol. 18 (28): 75-78 [Abstract] ( 51 ) HTML (1 KB) PDF (859 KB) ( 43 )

	79	Application of “micro class+flipped classroom” in ultrasonic diagnosis teaching
		LIU Ying WANG Lingling LI Haixia CHENG Wen ZHANG Yanhua ZHENG Xiulan
		Objective To explore the application value of “micro class+flipped classroom” in ultrasonic diagnosis teaching. Methods Eighty Grade 2017 undergraduate students majoring in imaging medicine and nuclear medicine of Harbin Medical University and practicing in Department of Ultrasound, Harbin Medical University Cancer Hospital from January 2020 to January 2021 were selected and divided into observation group (traditional teaching) and control group (micro class+flipped class) by random number table method, with 40 students in each group. At the end of the course, the results of theoretical knowledge assessment, operational skills assessment, and teaching satisfaction of the two groups were compared. Before and after the course, the California critical thinking scale was used to evaluate the two groups of critical thinking tendencies, and the assessment results were compared. Results After the course, the theoretical knowledge assessment scores, operational skills assessment scores and total scores, and satisfaction of the observation group were higher than those of the control group, with statistically significant differences (P ＜ 0.05). At the end of the course, the scores and total scores of all dimensions of the California critical thinking scale in both groups were higher than before the course, and the observation group was higher than the control group, the differences were statistically significant (P ＜ 0.05). Conclusion The application of “micro class + flipped classroom” in ultrasonic diagnosis teaching can not only improve students’ critical thinking ability, but also effectively improve the teaching quality and students’ satisfaction. Micro class; Flipped classroom; Ultrasonic diagnostics; Traditional teaching
		2021 Vol. 18 (28): 79-82 [Abstract] ( 58 ) HTML (1 KB) PDF (756 KB) ( 57 )

	83	Thoughts about online and offline mixed teaching mode in medical colleges
		ZHOU Xiaotao1 ZHENG Jia1 ZHAO Yunjuan1 Dilina·Borati1 Gulibahar·Nitin1 WANG Song1 ZHOU Wentao1,2
		With the development of information education, a steady stream of knowledge is growing exponentially on all kinds of platforms. Online and offline hybrid education model can provide a multi-dimensional knowledge output platform to meet the development needs of the times. In order to make up to the defects of traditional education methods, colleges and universities can use the modern network platform to explore a hybrid teaching system which combined the online education and the traditional teaching, and it is particularly important to build a teaching method suitable for the medical courses. Based on the teaching characteristics of medical colleges and universities, this paper shows the application of online and offline mixed teaching method from the selection of pre-class teaching platform, the design of in-class teaching method, and the evaluation of after-class quality, and it also shows the thought on the high-quality teaching methods suitable for medical colleges and universities.
		2021 Vol. 18 (28): 83-86 [Abstract] ( 122 ) HTML (1 KB) PDF (693 KB) ( 50 )

	87	Qualitative study of real experience of standardized training nurses in operating room on operation cooperation
		GUO Yunqing1 DIAO Rui1 SHU Juan1 JIN Xianrong2▲
		Objective To analyze the real experience of standardized training nurses in operating room on operation cooperation. Methods Sixteen nurses who were trained in the operating room of Chongqing Jiangjin Central Hospital from January to December 2019 were selected as the research objects by the purpose sampling method. The interview outline was prepared, and five nurses were randomly selected for pre-interview, and the interview outline was revised according to the pre-interview results. After the interview outline was determined, the semi-structured in-depth interview method was adopted to ask questions based on the interview outline and collected the data of 16 standardized training nurses. Through Colaizzi’s 7-step phenomenological analysis method, the data of 16 standardized training nures were coded, compared and summarized repeatedly, and then the real experience of operation cooperation of the operating room standardized training nurses was summarized. Results From the actual experience of the operation room training nurses in the operation cooperation process, four themes were summarized: low identifability of on-site teaching content, different teaching content from actual operation, psychological pressure caused by operating room environment, lack of initiative in learning and lack of participation. Conclusion Operating room teachers should update teaching concepts and skills, improve the ability in teaching, to correct and comprehensive teaching evaluation and to enhance gauge from the nurse’s interest in learning, encourage the active participation of its operation, and improve the operation coordination, and take measures to reduce the operation in the process of teaching work environment to bake nurses psychological pressure gauge.
		2021 Vol. 18 (28): 87-90 [Abstract] ( 151 ) HTML (1 KB) PDF (753 KB) ( 46 )

	91	TED-based cultivation and practice of general academic English oral presentation competence for medical undergraduates
		LU Lu1 WANG Haojue2 ZHAO Linlin1 HAN Ye1
		As a general academic English skill, oral presentation competence is one of the learning objectives of academic English course at undergraduate level. In light of the problems existing in oral presentations of medical undergraduates of Naval Medical University, this research explores ways to improve their oral presentation capabilities in teaching practice. In the medical English course for second-year medical undergraduates, the teacher introduces TED model and successful TED strategies, clarifies the grading rules, adopts a student-centered approach with major-orientated teaching design, and integrates content, language and skills to comprehensively cultivate students’ oral presentation ability. Finally, this paper puts forward suggestions to enhance presentation competence of medical undergraduates.
		2021 Vol. 18 (28): 91-94 [Abstract] ( 65 ) HTML (1 KB) PDF (898 KB) ( 147 )

	95	Analysis on the survival and influencing factors of patients with hemodialysis diabetic nephropathy
		TANG Yingchun DONG Xiongjun TANG Lijuan WANG Zhengxiang ZHANG Jing▲
		Objective To explore the survival of diabetic nephropathy hemodialysis patients and influencing factors. Methods A total of 95 patients confirmed diabetic nephropathy and underwent hemodialysis admitted to the Second People’s Hospital of Wuhu, Anhui Province from February 2014 to February 2018 were followed up. Follow-up ended in February 2021, with death as the study’s termination event. The general data, blood biochemical, and cardiovascular disease indicators were collected. Cox regression was used to analyze the risk factors of death in diabetic nephropathy hemodialysis patients. Results The follow-up time ranged from 16 to 54 months, with a median follow-up time of 30.5 months. At the end of follow-up, 52 of all cases survived and 43 cases died. Estimated glomerular filtration rate and total cholesterol levels of the dead patients were lower than those of the surviving patient and the proportion of C-reactive protein, low density lipoprotein, blood phosphorus, proportion of patients with coronary heart disease, and myocardial ischemia were higher than those of the surviving patients, with statistical significance (P ＜ 0.05). Multivariate analysis showed that high blood phosphorus, complicated with coronary heart disease and myocardial ischemia were independent risk factors for death in diabetic nephropathy patients on hemodialysis (HR ＞ 1, P ＜ 0.05). Conclusion During hemodialysis treatment for diabetic nephropathy patients, attention should be paid to the prevention of coronary heart disease and myocardial ischemia, and the reduction of blood phosphorus level.
		2021 Vol. 18 (28): 95-97,102 [Abstract] ( 118 ) HTML (1 KB) PDF (613 KB) ( 27 )

	98	Association of triglyceride-glucose index with risk of non-alcoholic fatty liver disease in patients with polycystic ovary syndrome
		FU Jiarong ZHU Yuchen YU Jie LIU Wei TAO Tao
		Objective To investigate the relationship between triglyceride-glucose index (TyG) and the risk of non-alcoholic fatty liver disease (NAFLD) in patients with polycystic ovary syndrome (PCOS). Methods A total of 350 PCOS patients admitted to the Department of Endocrinology and Metabolism, Renji Hospital, Shanghai Jiao Tong University School of Medicine from January 2017 to December 2020 were selected. According to whether they had NAFLD or not, they were divided into NAFLD group (201 cases) and non-NAFLD group (149 cases). TyG, lipid accumulation index (LAP) and visceral adiposity index (VAI) were calculated. Spearman correlation coefficient was used to analyze the correlation between TyG and liver function, glucolipid metabolism and reproductive indexes. Logistic univariate and multivariate analysis was used to analyze the correlation between TyG, LAP, VAI, and NAFLD in PCOS patients. Results There were statistically significant differences in clinical indicators, TyG, LAP, and VAI between the two groups (P ＜ 0.05). Correlation analysis showed that TyG was positively correlated with glutamic-pyruvic transaminase, glutamic-oxalacetic transaminase, γ-glutamyl transpeptidase, total cholesterol, low density lipoprotein cholesterol, area under insulin curve and free androgen index (rs ＞ 0, P ＜ 0.05). And it was negatively correlated with high density lipoprotein cholesterol, sex hormone-binding globulin, and anti-Müllerian hormone (rs ＜ 0, P ＜ 0.05). Univariate logistic regression analysis showed that age, body mass index, homeostasis model assessment-IR, free androgen index, glutamic-pyruvic transaminase, TyG, LAP, and VAI were all risk factors for NAFLD in PCOS patients (OR ＞ 1, P ＜ 0.05). In order to compare the relationship between TyG, LAP, VAI, and NAFLD in PCOS patients and avoid the interaction between the indexes, they were stratified by quartile, and the subjects were included in four subgroups of every index, respectively. Multivariate logistic regression was performed to correct confounding factors. The results showed that TyG ＞ 7.95, LAP ＞ 15.85, and VAI ＞ 1.91 were independent risk factors for NAFLD in PCOS patients (OR ＞ 1, P ＜ 0.05). Conclusion TyG index has certain value for the auxiliary diagnosis of NAFLD in PCOS patients.
		2021 Vol. 18 (28): 98-102 [Abstract] ( 107 ) HTML (1 KB) PDF (581 KB) ( 64 )

	103	Visual analysis of the application of electromyography in the field of rehabilitation medicine in domestic based on CiteSpace
		FU Qiuju1,2 XU Jingxuan3 GAO Ruixue4 LIU Jie5
		Objective To analyze the application of electromyography in the field of rehabilitation medicine in China by the application of visualization methods. Methods Relevant literatures of electromyography in rehabilitation medicine collected by China National Knowledge Infrastructure from January 1, 2000 to June 10, 2020 were searched, and visualization analysis was performed with CiteSpace software to understand the research status and hot spots in this field. Results A total of 984 articles were included. The number of articles increased exponentially. The topest magazine in terms of volume of publication was Chinese Journal of Rehabilitation Medicine. The author who had published the most articles was Feng Xiaodong. Dou Zulin’s team members were the most. The research institution that published the most articles was the School of Medical Devices and Food of Shanghai University of Science and Technology. After removing keywords related to the subject, “Stroke” was the most frequent and the highest degree centrality keyword. Conclusion The application of electromyography in the field of rehabilitation medicine mainly included clinical research and basic technical research. The research on the application of electromyography in the rehabilitation of patients with stroke was the most.
		2021 Vol. 18 (28): 103-107，112 [Abstract] ( 148 ) HTML (1 KB) PDF (1546 KB) ( 82 )

	108	Predictive value of the ratio of mean platelet volume to platelet count in the prognosis of community-acquired pneumonia
		YUAN Xiaoyu ZHANG Tieshuan
		Objective To explore the predictive value of the ratio of mean platelet volume to platelet count (MPV/PLT) in the prognosis of community acquired pneumonia (CAP). Methods A total of 223 CAP patients who were hospitalized in the Second Affiliated Hospital of Zhengzhou University from January 2018 to July 2020 were selected. According to the prognosis of hospitalized 28 days patients were divided into survival group and death group, including 169 cases in the survival group and 54 cases in the death group. The clinical data of the two groups were compared, the correlation between MPV/PLT and procalcihonin (PCT) and C-reactive protein (CRP) was analyzed, logistic regression was used to analyze independent risk factors that affect the prognosis of CAP. The receiver operating characteristic curve (ROC) was drawn to evaluate the prognostic value of MPV/PLT, the Kaplan-Meier survival analysis curve was drawn according to the best cut-off value. Results There were no significant differences in age, sex and white blood cell count between the two groups (P ＞ 0.05); compared with the death group, the percentage of neutrophils, PCT, CRP, MPV and MPV/PLT were lower, and PLT was higher (P ＜ 0.05). There was a positive correlation between MPV/PLT and PCT and CRP (r = 0.483, 0.489, P ＜ 0.05). The logistic regression analysis showed that MPV/PLT was an independent risk factor affecting the prognosis of patients. The area under curve of MPV/PLT was 0.773, the sensitivity was 85.2%, the specificity was 62.1%, the best cut-off value was 0.0645, and the 95% CI: 0.703-0.842 (P ＜ 0.05). There were 110 patients in the MPV/PLT≥0.0645 group, and 113 patients in the other group. The PCT, CRP and mortality rates in the MPV/PLT≥0.0645 group were higher than the other group (P ＜ 0.05). The cumulative survival rate of MPV/PLT≥0.0645 group was lower than that of MPV/PLT < 0.0645 group (Log-rank=37.974, P ＜ 0.05). Conclusion MPV/PLT may be an independent risk factor affecting the prognosis of CAP and has good clinical value in predicting the prognosis of patients.
		2021 Vol. 18 (28): 108-112 [Abstract] ( 109 ) HTML (1 KB) PDF (768 KB) ( 44 )

	113	Comparison of efficacy of Cefuroxime and Amoxicillin in the eradication treatment of Helicobacter pylori
		LIU Minzhi LI Yunze WEI Tianling CAI Huaiyang QIN Min
		Objective To compare the efficacy and safety of Cefuroxime and Amoxicillin in the eradication treatment of Helicobacter pylori (Hp). Methods A total of 160 patients diagnosed with Hp infection in the Outpatient Department of Liuzhou People’s Hospital of Guangxi Zhuang Autonomous Region from December 2017 to July 2020 were selected as the research subjects. Among them, 80 were initially treated patients who had not received previous Hp eradication treatment, and 80 patients were treated with bismuth drug quadruple regimen for 14 days to eradicate Hp after treatment failure. According to random number table method they were divided into treated first Cefuroxime, first Amoxicillin group and re-treat Cefuroxime and re-treat Amoxicillin group, with 40 cases in each group. Based on Rabeprazole, Furazolidone, and Colloidal bismuth pectin, combination respectively Cefuroxime or Amoxicillin Hp eradication therapy, treatment discontinuation ended at least four weeks after the review of Hp. The eradication rate of Hp and the incidence of adverse reactions in each group were compared. Results There was no significant difference in the eradication rate of Hp between first Cefuroxime group and first Amoxicillin group (P ＞ 0.05). There was no significant difference in the eradication rate of Hp between the re-treat Cefuroxime group and the re-treat Amoxicillin group (P ＞ 0.05). There was no statistical significance in the total incidence of adverse reactions among all groups (P ＞ 0.05). Conclusion There is no significant difference in the eradication rate of Hp between the quadruple therapy containing Cefuroxime and Amoxicillin, and similar eradication rates are obtained for both initial treatment and retreatment. For some patients who are not suitable for Penicillin, Cefuroxime may be a good alternative to Amoxicillin.
		2021 Vol. 18 (28): 113-116 [Abstract] ( 101 ) HTML (1 KB) PDF (612 KB) ( 47 )

	117	Comparative study of Oxycodone or Sufentanil combined with Etomidate for anesthesia induction in patients with moyamoya disease
		ZHAO Shuang1,2 YU Yingqun2 WANG Baoguo1▲
		Objective To investigate the hemodynamic changes and anesthesia quality of patients with moyamoya disease treated with equivalent dose of Oxycodone and Sufentanil combined with Etomidate during anesthesia induction. Methods A total of 80 patients with moyamoya disease who admitted to Nanyuan District, the Fifth Medical Center, General Hospital of Chinese People’s Liberation Army from May to November 2019 were selected as study objects. They were divided into Oxycodone group (OX group) and Sufentanil group (SF group), with 40 cases in each group. After entering the operating room, venous access was established and invasive arterial monitoring was performed. Anesthesia induction: Oxycodone Hydrochloride Injection 0.25 mg/kg was injected intravenously in OX group, and Sufentanil Citrate Injection 0.25 μg/kg was injected intravenously in SF group, cough, muscle spasm, and respiratory depression were observed within two minutes. Then, Etomidate 0.3 mg/kg, Midazolam 2 mg, Penehyclidine Hydrochloride 0.3 mg, Granisetron 3 mg and Rocuronium 0.6 mg/kg were injected intravenously in both groups. After the patients were fully relaxed, laryngeal mask was inserted and mechanical ventilation was performed. Heart rate (HR) and mean arterial pressure (MAP) were observed and recorded before anesthesia induction (T0), two minutes after Oxycodone/Sufentanil injection (T1), before laryngeal mask implantation (T2), immediately after laryngeal mask implantation (T3) and one minutes after laryngeal mask implantation (T4). Results The incidence of cough in OX group was lower than that in SF group, and the difference was statistically significant (P < 0.05). There were no significant differences in the incidence of dizziness and nausea, and respiratory depression between two groups (P > 0.05). In SF group, HR and MAP at T1 were higher than those at T0, and the differences were statistically significant (P < 0.05). HR and MAP at T1 in OX group were lower than those in SF group, and the differences were statistically significant (P < 0.05), but there were no significant differences between HR and MAP in two groups at other time points (P > 0.05). Conclusion The effect of Oxycodone combined with Etomidate on anesthesia induction of moyamoya disease is safe and reliable, and the incidence of adverse reactions is lower than Sufentanil induction, and the hemodynamics is stable.
		2021 Vol. 18 (28): 117-120 [Abstract] ( 89 ) HTML (1 KB) PDF (477 KB) ( 15 )

	121	Application of small dose Dexmedetomidine in the recovery period of general anesthesia in children with OSAHS tonsillectomy
		REN Rong1 DENG Haibo1 LI Zhen1 CAI Ning1 ZHANG Xinhai2
		Objective To investigate the effect of small dose Dexmedetomidine in the recovery period of general anesthesia in children with obstructive sleep apnea-hypopnea syndrome (OSAHS) tonsillectomy, and to provide reference for clinical selection of anesthesia program. Methods A total of 100 children with OSAHS who underwent tonsillectomy in Fuyang People’s Hospital, Anhui Province from January 2018 to December 2019 were selected as study subjects. According to the random number table method, they were divided into observation group (50 cases) and control group (50 cases). Children of two groups used the same anesthesia induction and maintenance plan. Control group was given 1 μg/kg Dexmedetomidine intraoperatively, and observation group was given 0.5 μg/kg Dexmedetomidine intraoperatively. Ramsay sedation score after extubation, postoperation visual analogue score (VAS), recovery and adverse reactions in the recovery period were compared between two groups. Results There were no significant differences in Ramsay sedation score after extubation and postoperation VAS score between two groups (P > 0.05). The respiratory recovery time, consciousness recovery time and extubation time in the recovery period in observation group were shorter than those in control group, and the differences were highly statistically significant (P < 0.01). The total incidence of adverse reactions in observation group was lower than that in control group in the recovery period, and the difference was statistically significant (P < 0.05). Conclusion Dexmedetomidine 0.5 μg/kg has good sedation and analgesia effect during the recovery period of general anesthesia after OSAHS tonsillectomy in children, and compared with 1.0 μg/kg Dexmedetomidine, patients have quicker recovery of respiration and consciousness, and fewer adverse reactions.
		2021 Vol. 18 (28): 121-124 [Abstract] ( 149 ) HTML (1 KB) PDF (474 KB) ( 52 )

	125	Influence of anxiety state before anesthesia on agitation during the recovery period of patients with radical gastrectomy under general anesthesia
		WU Zhijuan1 WU Yanhong2 WANG Huise3
		Objective To analyze the influence of anxiety state before anesthesia on agitation during the recovery period of patients with radical gastrectomy under general anesthesia. Methods The clinical data of 100 patients who underwent radical gastrectomy for gastric cancer in No.82 Military Hospital of Chinese People’s Liberation Army Ground Force from January 2020 to January 2021 were analyzed. All patients received general anesthesia, the anxiety state of all patients before anesthesia were assessed, and the occurrence of agitation during the recovery period in all patients was counted, according to the occurrence of agitation, they were divided into occurrence group and non-occurrence group. At the same time, the baseline data questionnaire was designed, the effect of anxiety state before anesthesia on emergence agitation of patients with radical gastrectomy under general anesthesia was analyzed by univariate and multivariate analysis. Results Among the 100 patients with radical gastrectomy under general anesthesia, nine patients developed agitation during the recovery period, with an incidence of 9%. There were statistically significant differences in diabetes mellitus and anxiety between two groups (P < 0.05). Logistic regression analysis showed that diabetes mellitus and anxiety were the influential factors of agitation in patients underwent radical gastrectomy under general anesthesia (OR > 1, P < 0.05). Conclusion Patients with radical gastrectomy under general anesthesia have a higher risk of agitation during recovery, which may be affected by anxiety state before anesthesia.
		2021 Vol. 18 (28): 125-128 [Abstract] ( 306 ) HTML (1 KB) PDF (499 KB) ( 40 )

	129	Consideration and discussion on the acupoint compatibility on acupuncture and moxibustion in treating insulin resistance obesity
		WANG Wenyan1 CHEN Rui2 LIANG Fengxia3
		Based on the basic pathogenesis of insulin resistant obesity and gastrointestinal motility, the author discusses the compatibility and methods of acupoint on acupuncture and moxibustion in the prevention and treatment of insulin resistant obesity: focusing on the basic pathogenesis, paying attention to the train of thought of the combination of syndrome differentiation and meridian differentiation; giving play to the characteristics and advantages of acupuncture and moxibustion “preventing disease”, and advocating the method of “manifestation and root cause with acupoint”; drawing lessons from modern scientific research achievements, paying attention to the scientific connotation of acupoint compatibility. With reference to this idea and method, the basic prescription of acupuncture and moxibustion in treating insulin resistant obesity is preliminarily established: zúsānlǐ, tàibái, zhōngwǎn, guānyuán, fēnglóng, xiàjùxū and shàngjùxū, in order to provide reference for clinical practice and scientific research of acupuncture and moxibustion in treating insulin resistant obesity.
		2021 Vol. 18 (28): 129-132 [Abstract] ( 163 ) HTML (1 KB) PDF (643 KB) ( 72 )

	133	Template construction of “combined treatment based on diagnosed disease, pulse and syndromes” based on the knowledge element indexing
		LI Yiran ZHONG Xianggen YANG Feng LI Qianqian HOU Jianchen ZHOU Ranran LI Ran TAO Xiaohua
		“Combined treatment based on diagnosed disease, pulse and syndromes” is a clinical diagnosis and treatment mode derived from Zhang Zhongjing’s theory. In order to fully explore this characteristic model of diagnosis and treatment from ancient books of traditional Chinese medicine, so as to better serve clinical practice, this study construct a knowledge element indexing template of the mode “combined treatment based on diagnosed disease, pulse and syndromes” which adopts a four-step diagnosis and treatment decision-making schema of “disease differentiation- normal pulse- syndrome analysis-definite treatment” as the line of thinking, and contains 31 knowledge elements such as disease name, etiology, differential diagnosis, main pulse, concurrent pulse, syndrome differentiation, pathogenesis, treatment, prescription, medicine, acupuncture, cure reaction, prognosis, mistreatment, and so on, to carry out in-depth indexing of ancient books of traditional Chinese medicine and create a knowledge base of ancient books of traditional Chinese medicine. This indexing method can comprehensively show the knowledge connotation of the theory of distinguishing and treating ancient books of traditional Chinese medicine, fully excavate the value of ancient books of traditional Chinese medicine, provide the basis for the database retrieval of ancient books of traditional Chinese medicine and the visualization of traditional Chinese medicine knowledge, and realize the deep integration of ancient books of traditional Chinese medicine and clinical needs.
		2021 Vol. 18 (28): 133-138 [Abstract] ( 52 ) HTML (1 KB) PDF (1217 KB) ( 168 )

	139	Study of distribution of traditional Chinese medicine syndromes of acquired immunodeficiency syndrome in Lincang, Yunnan based on latent class model
		WANG Xing1,2 ZHOU Qing1 LI Qin1 YE Fang3 QU Yuan3 WEN Weibo4
		Objective To explore the regularities of distribution of traditional Chinese medicine syndromes of acquired immunodeficiency syndrome in Lincang area of Yunnan Province. Methods Clinical data of 150 acquired immunodeficiency syndrome patients admitted to Linxiang Hospital of Traditional Chinese Medicine of Yunnan Province from June 2020 to January 2021 were collected to explore the internal correlation between symptoms and syndrome types by latent class model analysis. Results The top 20 main symptoms were greasy fur, white fur, weakness, amnesia, deep pulse, soreness and weakness of waist and knees, dreaminess, reddish tongue, fatigue, lumbago, slippery pulse, bitter taste in mouth, insomnia, arthralgia, alopecia, nocturia, plump tongue, less complexion, heavy body drowsiness, and less menstruation. The latent class 3 had the minimum Bayesian information criterion value (12 496.6106), that was, Model 3 was the best model. According to traditional Chinese medicine symptoms, 150 acquired immunodeficiency syndrome patients were divided into three classes: 71 cases (47.33%) of syndrome of qi deficiency of spleen and kidney, 70 cases (46.67%) of syndrome of phlegm-dampness due to spleen deficiency, 9 cases (6.00%) of spleen-kidney deficiency pattern. Conclusion In Lincang area of Yunnan Province, the syndrome of acquired immunodeficiency syndrome is mixed with deficiency and solid syndrome, mainly deficiency syndrome, qi deficiency is the main pathogenesis, phlegm and dampness is the main pathological factor, and the disease location is mainly in spleen and kidney
		2021 Vol. 18 (28): 139-143,155 [Abstract] ( 87 ) HTML (1 KB) PDF (976 KB) ( 139 )

	144	Clinical experience of Professor Mao Dexi in treating palpitation based on syndrome differentiation
		PAN Haitao1 LU Yongping2
		Professor Mao Dexi, the first national famous Chinese medicine doctor, believes that the main pathogenesis of palpitation is “deficiency complicated with excess”. The deficiency is mostly caused by the insufficiency of pectoral qi, and the excess is mostly caused by blocked venation. The lack of pectoral qi and the blocked of the venation often interact with each other, which causes palpitation. Professor Mao Dexi pays attention to the combination of constitution and syndrome in the aspect of syndrome differentiation, pays attention to invigoration and interflow in the aspect of prescription-medicine application. In clinic, palpitation is often divided into six common syndrome types, including insufficiency of qi and blood, devitalization of heart yang, timidity due to deficiency of heart qi, phlegm-fire disturbing heart, blood stasis blocking heart vessel, qi deficiency and blood stasis. Based on the study of the medical books of ancient doctors, and combined with his own clinical experience, Professor Mao Dexi makes “Xinji Bawei Prescription” by himself in the treatment of palpitation, which has the effects of benefiting qi and replenishing blood, promoting blood circulation for removing blood stasis, calming mind and palpitation, and the effect is remarkable in clinical treatment.
		2021 Vol. 18 (28): 144-147 [Abstract] ( 102 ) HTML (1 KB) PDF (646 KB) ( 32 )

	148	Effect of Huazhuo Jiedu Decoction combined with holographic meridian scraping in the treatment of chronic atrophic gastritis with syndrome of internal retention of turbidity
		CHEN Guijing YIN Xiaohua ZHANG Wan
		Objective To observe the clinical efficacy of Huazhuo Jiedu Decoction combined with holographic meridian scraping in the treatment of chronic atrophic gastritis with syndrome of internal retention of turbidity. Methods A total of 80 chronic atrophic gastritis patients with syndrome of internal retention of turbidity from August 2019 to August 2020 in Department of Spleen and Stomach of Hebei Hospital of Traditional Chinese Medicine were selected as the research subjects. They were randomly divided into the treatment group and the control group, with 40 cases in each group. The control group was treated with Huazhuo Jiedu Decoction, the treatment group was treated with Huazhuo Jiedu Decoction combined with holographic meridian scraping, and the treatment course of the two groups was three months. The traditional Chinese medicine syndrome scores and 36-item short form health survey evaluation were observed between the two groups before and after treatment, the clinical efficacy of the two groups was compared. Results After treatment, the syndrome scores of stomach pain, stomach distension, poor appetite, reverse acid, heartburn in both groups were lower than those before treatment (P ＜ 0.05), and the syndrome scores of gastric upset and belching in the treatment group were significantly lower than those before treatment (P ＜ 0.05). After treatment, the symptom scores of gastric upset and belching in the treatment group were significantly lower than those in the control group, the differences were statistically significant (P ＜ 0.05). The total effective rate of the treatment group was significantly higher than that of the control group (P < 0.05). After treatment, the scores of somatic pain, energy feeling, emotional factors, mental health in two groups were higher than those before treatment, which of the treatment group were higher than those in the control group (P < 0.05). Conclusion Huazhuo Jiedu Decoction combined with holographic meridian scraping in the treatment of chronic atrophic gastritis patients with syndrome of internal retention of turbidity has exact efficacy, and it is better than the treatment of Huazhuo Jiedu Decoction alone.
		2021 Vol. 18 (28): 148-151 [Abstract] ( 91 ) HTML (1 KB) PDF (645 KB) ( 88 )

	152	Correlation between cerebral glucose metabolism and cognitive function in Alzheimer’s disease patients based on PET/CT
		WANG Yanyan1 LI Xiaoxia2 XIA Huan3 LUO Qin4
		Objective To explore the correlation between cerebral glucose metabolism and cognitive function in Alzheimer’s disease patients based on positron emission tomography / computed tomography (PET/CT). Methods Clinical data of 31 patients with primary AD in Gansu Provincial People’s Hospital (hereinafter referred to as “our hospital”) from September 2016 to October 2019 were analyzed. According to the mini-mental state examination (MMSE), the patients were divided into mild to moderate AD group (22 cases, 12≤MMSE< 24 points) and severe AD group (9 cases, MMSE< 12 points). The control group was 57 healthy people who underwent physical examination in our hospital during the same period. In PET/CT examination, the imaging agent was fluorodeoxy glucose (18F-FDG), the image fusion and reconstruction were processed by PHILIPS Syntegra software, and SUVavg (Br/Bl) value was obtained after the correction of interest area. At the same time, the correlation between brain glucose metabolism and cognitive function in AD patients was analyzed. Results There was a positive correlation between SUVavg (Br/Bl) value in bilateral temporal lobe and recall power score in MMSE score in AD patients (r = 0.516, P ＜ 0.05). SUVavg (Br/Bl) value of right parietal lobe in mild to moderate AD group was lower than that in control group (P < 0.05). Conclusion The progressive decrease of 18F-FDG glucose metabolism in temporal lobe of AD patients is consistent with the decline of the ability to memorize score in MMSE, and PET/CT can earlier reflect the functional damage of right parietal lobe in mild to moderate AD patients.
		2021 Vol. 18 (28): 152-155 [Abstract] ( 137 ) HTML (1 KB) PDF (465 KB) ( 57 )

	156	Study on the diagnostic value of ultra-high b-value DWI-IVIM combined with DCE-MRI in prostate cancer
		WANG Song XIA Jinxiang
		Objective To investigate the diagnostic value of ultra-high multiple diffusion sensitivity coefficients (b-value) diffusion weighted imaging-intravoxel incoherent motion (DWI-IVIM) combined with dynamic contrast-enhancement magnetic resonance imaging (DCE-MRI) in prostate cancer. Methods The clinical data of 80 patients with suspected prostate cancer admitted to the Second People’s Hospital of Hefei from February 2017 to July 2020 were analyzed. The apparent diffusion coefficient (ADC) and f values of the central region, transitional region, and peripheral region of patients diagnosed by ultra-high b-value DWI-IVIM; volume conversion constant (Ktrans) and rate constant (Kep) values of prostate cancer focal area, hyperplastic area, and normal area were compared; pathological examination results were taken as the gold standard to compare the diagnostic efficacy of different methods. Results ADC values of central region, transitional region, and peripheral region of prostate cancer patients were lower than those of prostate hyperplasia patients, and f values were higher than those of prostate hyperplasia patients, and the differences were statistically significant (P < 0.05). There were significant differences in Ktrans and Kep values between prostate cancer focal area, hyperplasia area, and normal area (P < 0.05). The sensitivity and specificity of ultra-high b-value DWI-IVIM were 91.84% and 77.42% respectively; the sensitivity and specificity of DCE-MRI were 91.84% and 74.19% respectively; the sensitivity and specificity of the combined detection were 95.92% and 90.32% respectively. Conclusion Comparing with ultra-high b-value DWI-IVIM or DCE-MRI single detection, the sensitivity and specificity of combined detection are significantly increased, and has higher diagnostic efficacy for prostate cancer.
		2021 Vol. 18 (28): 156-159 [Abstract] ( 127 ) HTML (1 KB) PDF (601 KB) ( 34 )

	160	Molecular epidemiology and drug resistance mechanism analysis of carbapenem-resistant Klebsiella pneumoniae isolated from patients and object surface in the intensive care unit
		CHEN Tao TANG Jiao DU Jingjing LIU Xiaohua CHEN Jing
		Objective To understand the drug resistance mechanism and molecular epidemiological characteristics of carbapenem-resistant Klebsiella pneumoniae (CRKP) isolated from patients and object surface in the intensive care unit (ICU), and to adopt reasonable strategies to block its transmission in hospital based on the actual situation of this ward, so as to provide an important basis for clinical rational drug use and nosocomial infection control. Methods A total of 29 strains of CRKP isolated from ICU patients and object surface in Xindu District People’s Hospital of Chengdu (hereinafter referred to as “our Hospital”) from July 2019 to June 2020 were collected. The antimicrobial resistance of common clinical antibiotics was detected by MicroScan WalkAway40 bacterial susceptibility analyzer and paper diffusion method. Five common carbapenem-resistant genes were detected by polymerase chain reaction (PCR) amplification and DNA sequence analysis. The gene correlation among the strains was detected by multilocus sequence typing (MLST) and pulsed field gel electrophoresis (PFGE). Results A total of 29 strains of CRKP were sensitive to Tigecycline and Polymyxin, and had high sensitivity to Amikacin and Gentamicin, and high resistance to other common antibacterial drugs. PCR and DNA sequencing showed that among 29 strains of CRKP, only one strain was KPC-2 type. The other 28 strains were NDM-1 type. No other resistance genotypes were detected. MLST and PFGE detection results showed that 29 strains of CRKP were classified into six types, with ST12 type as the main type. A total of 22 strains of ST12 type CRKP, 11 strains of ST12/A type and six strains of ST12/B type were detected. The object surface strain was ST12/A type. Conclusion In ICU ward of our hospital, NDM-1 carbapenemase ST12/A type is the main type of CRKP, and the isolated strains on the object surface are consistent with the epidemic strains in this area, with high homology. Relevant departments should strengthen the intervention of nosocomial transmission of CRKP, clarify the transmission route, and take a series of prevention and control measures to prevent the spread of drug-resistant strains in the hospital.
		2021 Vol. 18 (28): 160-163,172 [Abstract] ( 114 ) HTML (1 KB) PDF (893 KB) ( 52 )

	164	Effects of health education and nursing intervention based on symptom management strategy on disease awareness rate and negative emotions of parents of children with pneumonia
		XIANG Qiong1 QIAO Hongyu1 WANG Qian1 LI Ni2▲
		Objective To explore the effects of health education and nursing intervention based on symptom management strategy on the disease awareness rate and negative emotions of parents of children with pneumonia. Methods A total of 128 children with pneumonia admitted to First Affiliated Hospital of Air Force Military Medical University of Chinese People’s Liberation Army from January 2018 to December 2020 were selected as the research subjects, according to random number table method, they were divided into control group and observation group, with 64 cases in each group. The control group received routine health education nursing intervention, and the observation group received health education nursing intervention based on symptom management strategy. Symptom improvement and prognosis of children, disease awareness rate, self-rating anxiety scale (SAS) score, self-rating depression scale (SDS) score and compliance behavior of parents were compared between the two groups. Results The cough resolution time, fever reduction time, recurrence rate within three months and readmission rate in the observation group were lower than those in the control group, and the differences were statistically significant (P ＜ 0.05). The disease awareness rate of parents in observation group was higher than that in control group, and the difference was statistically significant (P ＜ 0.05). After intervention, SAS and SDS scores of the two groups were lower than before intervention, and observation group was lower than control group, the differences were statistically significant (P ＜ 0.05). The rates of parents in the observation group adhering to medical advice, keeping warm, physical exercise and scientific diet compliance behavior were higher than those in the control group, with statistical significance (P ＜ 0.05). Conclusion The application of health education and nursing intervention based on symptom management strategy in pediatric pneumonia can alleviate the symptoms of children, improve the prognosis, but also enhance the parents’ cognition of the disease, eliminate the negative emotions of parents, and improve the compliance behavior.
		2021 Vol. 18 (28): 164-167 [Abstract] ( 167 ) HTML (1 KB) PDF (650 KB) ( 28 )

	168	Comparative analysis on situation and trend of caregiver psychology in China and abroad based on CiteSpace software
		WANG Mi1 LIN Zheng1,2 ZHOU Meijing1 GU Zijun1 SUN Caiyun1
		Objective To compare the situation and trend of the caregiver psychology in China and abroad, so as to provide references for Chinese caregirers. Methods CiteSpace 5.6.R5 knowledge Graph software was used to perform visual analysis on caregivers’ psychological literature collected by CNKI, Wanfang and Web of Science core collection database from January 2010 to December 2019. Results A total of 2785 Chinese literatures and 7223 English literatures were included. In recent ten years, the annual publication volume showed an overall upward trend both in China and abroad. The top three publishing institutions in China were Central South University, Zhengzhou University and Fudan University, while the top three abroad were the King’s College London, the University of Toronto and the University of Melbourne. Caregivers of Alzheimer’s and mental illness had been paid attention to both in China and abroad, and caregivers of adolescence had been paid attention to abroad. Cross-sectional studies of caregiver positive psychology tended to be frontier, while relevant clinical evidences had begun to be studied abroad. Conclusion Research on psychology of caregivers in China has attracted attention, but there is still a gap between China and foreign countries. Domestic scholar should combine local resources to look out adolescent caregivers, focusing on the positive psychology of caregivers and its influencing factors, and carry out relevant intervention researches.
		2021 Vol. 18 (28): 168-172 [Abstract] ( 76 ) HTML (1 KB) PDF (1014 KB) ( 130 )

	173	Application of health education model based on information-motivation-behavior skills model in patients undergoing upper urinary tract stones surgery
		WANG Zhiyun HU Xiaoli ZHOU Ying YIN Liangmei▲
		Objective To explore the impact of health education based on the information-motivation-behavior skills model (IMB) on the healthy behavior and healthy lifestyle of patients after upper urinary tract stones surgery. Methods A total of 128 patients with upper urinary tract stones surgery treated in Nantong Hospital of Traditional Chinese Medicine, Jiangsu Province from March 2019 to October 2020 were selected as the study subjects. According to the random number table method, they were divided into experimental group and control group, with 64 cases in each group. The control group was given regular health education, and the experimental group jointly applied health education based on the IMB model. Follow-up for six months, the two groups of healthy behavior, specific healthy lifestyle, recurrence rate were compared. Results After six months of follow-up, the actual follow-up of the experimental group and the control group were 62 cases and 54 cases respectively. The health behavior scores of the two groups were higher than those of the same group before education, and the total scores of health responsibility, nutrition, stress response, exercise, and health behavior of the experimental group were higher than those of the control group (P ＜ 0.05). The scores of healthy lifestyle of the two groups were higher than before education in the same group, the experimental group had a higher daily score of drinking water every morning and evening, restricted diet, daily urine output ≥2000 ml, weight control through diet/exercise, and healthy lifestyle score than the control group (P ＜ 0.05); the stone recurrence rate of experimental groupwas lower than the control group (P ＜ 0.05). Conclusion Health education based on the IMB model can help enhance the health behavior of patients after upper urinary tract stones surgery, improve the quality of life, and reduce the recurrence rate of postoperative stones.
		2021 Vol. 18 (28): 173-176 [Abstract] ( 115 ) HTML (1 KB) PDF (653 KB) ( 55 )

	177	Impact of compound insulation on the stress response, coagulation function and insulation effect of patients undergoing abdominal surgery
		ZHANG Lijuan WANG Jingjing▲ YAN Li
		Objective To explore the effect of compound insulation on the stress response and coagulation function of abdominal surgery patients. Methods A total of 78 patients undergoing abdominal surgery admitted to Huai’an No.4 People’s Hospital from January to December 2019 were selected and divided into experimental group and control group by random number table method, with 39 cases in each group. The experimental group took compound heat preservation intervention, while the control group took conventional heat preservation intervention. The heat preservation effect, stress response, blood coagulation function and adverse reactions were compared between the two groups. Results There were statistically significant differences in body temperature at different time, groups, and interaction between the two groups (P ＜ 0.05). At 30, 60, 120 minutes, and at the end of the operation, the body temperature of the two groups were lower than before the operation, and the differences were statistically significant (P ＜ 0.05). After anesthesia, 30, 60, 120 minutes, and at the end of the operation, the body temperature of the experimental group were higher than those of the control group, and the differences were statistically significant (P ＜ 0.05). The differences in C-reactive protein (CRP), adrenaline (AD), norepinephrine (NE) content at different time, groups and interactions between the two groups were statistically significant (P ＜ 0.05). At 60 minutes after the operation and at the end of the operation, the levels of CRP, AD, and NE in the two groups were higher than those before anesthesia, and the differences were statistically significant (P ＜ 0.05); at 60 minutes after the operation and at the end of the operation, the contents of CRP, AD, and NE in the experimental group were significantly lower than those in the control group, and the differences were statistically significant (P ＜ 0.05). The differences in prothrombin time (PT), activated partial thromboplastin time (APTT) and fibrinogen (FBG) content at different time, groups and interactions between the two groups were statistically significant (P ＜ 0.05). At 60 minutes after the operation and at the end of the operation, the PT, APTT, and FBG content in the two groups were higher than those before anesthesia, and the differences were statistically significant (P ＜ 0.05); at 60 minutes after the operation and at the end of the operation, the PT, APTT, and FBG content in the experimental group were lower than those in the control group, and the differences were statistically significant (P ＜ 0.05). The incidence of adverse reactions in the experimental group was lower than that in the control group, and the difference was statistically significant (P ＜ 0.05). Conclusion Compound insulation can help relieve the stress response of patients undergoing abdominal surgery, maintain a relatively stable coagulation function, and reduce the occurrence of adverse reactions such as hypothermia.
		2021 Vol. 18 (28): 177-180,192 [Abstract] ( 108 ) HTML (1 KB) PDF (674 KB) ( 129 )

	181	Effect of dimensional map-guided rehabilitation nursing on postoperative functional recovery and psychological status of patients with carpal tunnel syndrome
		QI Jianmei JIA Yan▲
		Objective To analyze the influence of mind map-guided rehabilitation nursing on postoperative functional recovery and psychological status of patients with carpal tunnel syndrome. Methods A study was conducted on 80 patients with carpal tunnel syndrome who underwent surgical treatment in Jiangsu Provincial People’s Hospital from January 2019 to May 2020. According to a simple random sampling method, they were divided into a test group and a control group, each with 40 cases. All patients were treated with small incision decompression, the control group was given routine care, while the experimental group was given mind map-guided rehabilitation care. The health cognition scores, self-rating anxiety scale (SAS) and self-rating depression scale (SDS), self-assessment scale (PRWE) scores with wrist joints, clinical efficacy and complications of the two groups were compared. Results The postoperative health cognition scores of the two groups were higher than those before the operation, while the test group was higher than the control group, and the differences were statistically significant (P ＜ 0.05). The SAS and SDS scores of the two groups were lower than those before the operation, while the test group were lower than those of the control group, and the differences were statistically significant (P ＜ 0.05). The PRWE scores of the two groups were lower than those before the operation, while the test group was lower than the control group, and the differences were statistically significant (P ＜ 0.05). The excellent and good rate of the experimental group was significantly higher than that of the control group, and the difference was statistically significant (P ＜ 0.05). The total incidence of complications in the experimental group was significantly lower than that in the control group, and the difference was statistically significant (P ＜ 0.05). Conclusion Mind map-guided rehabilitation nursing can improve the health cognition of patients with carpal tunnel syndrome, and promote the improvement of postoperative mental state and functional recovery of patients.
		2021 Vol. 18 (28): 181-184,196 [Abstract] ( 89 ) HTML (1 KB) PDF (673 KB) ( 71 )

	185	Effects of nursing intervention combined with health education based on empowerment theory on self-efficacy and quality of life in patients with cystic acne treated with CO2 dot array laser
		WANG Xuemei HOU Yan BAI Jieling
		Objective To explore the influence of nursing intervention combined with health education based on empowerment theory on self-efficacy and quality of life in patients with cystic acne treated with CO2 dot array laser. Methods A total of 110 patients with cystic acne who underwent CO2 dot array laser treatment from January 2019 to December 2020 in 3201 Hospital of Hanzhong City were selected as the research objects. They were divided into a control group and an observation group by random number table method, 55 cases in each group. The control group was given conventional nursing intervention, while the observation group was given nursing intervention combined with health education based on the authorization theory on the basis of the control group. The general self-efficacy scale (GSES), 36-item short form health survey (SF-36) and compliance were compared between the two groups. Results The differences in self-efficacy between the two groups of difference time, groups, and interactions were statistically significant (P ＜ 0.05). Further pairwise comparison, intra-group comparison: the two groups of intervention two weeks, one month after the intervention was higher than before the intervention, and the differences were statistically significant (P ＜ 0.05); comparison between groups: the observation group was higher than the control group after two weeks and one month of intervention, and the differences were statistically significant (P ＜ 0.05). After the intervention, the scores of the physical, physiological, psychological, and social functions of the two groups were higher than those before the intervention, while the observation group was higher than the control group, and the differences were statistically significant (P ＜ 0.05). The compliance of the observation group was higher than that of the control group, and the difference was statistically significant (P ＜ 0.05). Conclusion Nursing intervention based on authorization theory combined with the application of health education can enhance the self-efficacy of patients with cystic acne treated with CO2 dot array laser, and improve their quality of life and compliance.
		2021 Vol. 18 (28): 185-188 [Abstract] ( 141 ) HTML (1 KB) PDF (649 KB) ( 64 )

	189	Application effect of humanistic care in the nursing of ear, nose and throat endoscopy
		YU Hongli LI Jun
		Objective To explore the application of humanistic care in the nursing of ear, nose and throat endoscopy and its influence on the self-rating anxiety score (SAS) and self-rating depression score (SDS). Methods A total of 192 patients who underwent ENT endoscopy at the Department of Otorhinolaryngology Head and Neck Surgery, Changzhi City People’s Hospital in Shanxi Province from September 2019 to August 2020 were selected and divided into two groups by random number table method. A total of 96 cases in the control group were treated with conventional ENT endoscopy and nursing; a total of 96 cases in the observation group, combined with the application of humanistic care on the basis of routine care in the control group. The SAS score and SDS score, comfort score and nursing satisfaction of the two groups before and after nursing were compared. Results After the intervention, the SAS and SDS scores of the two groups were lower than before the intervention, while the observation group was lower than the control group, and the differences were statistically significant (P ＜ 0.05). The comfort scores of the observation group were higher than those of the control group, and the differences were statistically significant (P ＜ 0.05). The nursing satisfaction of the observation group was higher than that of the control group, and the difference was statistically significant (P ＜ 0.05). Conclusion The application of humanistic care in the nursing of ENT endoscopy can effectively relieve the anxiety and depression of the patients, increase the comfort of the patients, and the patients are more satisfied with the nursing, which is worthy of further clinical promotion.
		2021 Vol. 18 (28): 189-192 [Abstract] ( 90 ) HTML (1 KB) PDF (647 KB) ( 56 )

	193	Application effect of traditional Chinese medicine rehabilitation nursing based on motivational behavior transformation in the recovery of puerperium
		YAN Yanyan SUN Xuli ZHAO Yi
		Objective To analyze the application effect of traditional Chinese medicine rehabilitation nursing based on the motivational behavior transformation in the recovery of puerperium, and to provide a basis for clinical nursing. Methods From December 2016 to December 2018, 80 cases of puerperium women receiving care in Lishui Hospital of Traditional Chinese Medicine in Zhejiang Province were divided into control group (40 cases) and observation group (40 cases) according to the random number table method. The control group was given conventional nursing intervention, while the observation group was given traditional Chinese medicine rehabilitation nursing intervention based on the motivational behavior transformation on the basis of the control group. One month later, the lactation effect, the amount of lochia, the disappearance time of lochia, the height of the uterine fundus, complications and nursing satisfaction were compared and analyzed between the two groups. Results The total effective rate of lactation in the observation group was higher than that in the control group, and the difference was statistically significant (P <0.05). The amount of lochia and the height of the fundus of the uterus in the observation group were lower than those in the control group, while the disappearance time of lochia was shorter than that in the control group, and the differences were statistically significant (P < 0.05). The total incidence of complications in the observation group was lower than that in the control group, and the difference was statistically significant (P < 0.05). The total nursing satisfaction of the observation group was higher than that of the control group, and the difference was statistically significant (P < 0.05). Conclusion Traditional Chinese medicine rehabilitation nursing based on motivational behavior transformation has a high application effect in the recovery of puerperium, which can significantly improve the recovery effect and satisfaction, reduce the incidence of complications, and is worthy of popularization and application in clinical nursing.
		2021 Vol. 18 (28): 193-196 [Abstract] ( 124 ) HTML (1 KB) PDF (673 KB) ( 58 )

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