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Research situation of the syndrome differentiation of micro-indexes of chronic heart failure |
ZHONG Senjie LI Jing LI Lin HU Siyuan YANG Meng ZHANG Qian XIONG Xiajun HU Zhixi |
Diagnostic Institute of Chinese Medicine, Hunan University of Chinese Medicine, Hunan Province, Changsha 410208, China |
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Abstract The typical external symptoms and signs of chronic heart failure appear relatively late, while the traditional four-diagnostic method failed to go deep into the micro level, which seriously restricts the development of syndrome differentiation. Micro-indexes obtained by modern detecting techniques can enrich the visual observation content of external images, and make up for the limitations of the traditional four-diagnostic method, thereby gradually becoming beneficial complements to the syndrome differentiation of chronic heart failure. This paper summarizes the research situation of micro-indexes such as cardiac function classification and related indicators, natriuretic peptides secreted by the heart, biological markers and other micro indexes in the syndrome differentiation of chronic heart failure, analyzes the correlation between different micro-indexes and the evolution of chronic heart failure syndromes, discusses the diagnostic value and limitations of each micro-indexes, and discussse the limitations of single index and the lack of specificity of some indexes at present, and puts forward some development ideas, such as introducing the concept of weight quantification, combined application of multiple indexes and the aid of system biology, in order to provide new ideas for the objectification of chronic heart failure syndrome differentiation.
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