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| Analysis on the survival and influencing factors of patients with hemodialysis diabetic nephropathy |
| TANG Yingchun DONG Xiongjun TANG Lijuan WANG Zhengxiang ZHANG Jing▲ |
| Department of Nephrology, Wuhu Second People’s Hospital, Anhui Province, Wuhu 241000, China |
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Abstract Objective To explore the survival of diabetic nephropathy hemodialysis patients and influencing factors. Methods A total of 95 patients confirmed diabetic nephropathy and underwent hemodialysis admitted to the Second People’s Hospital of Wuhu, Anhui Province from February 2014 to February 2018 were followed up. Follow-up ended in February 2021, with death as the study’s termination event. The general data, blood biochemical, and cardiovascular disease indicators were collected. Cox regression was used to analyze the risk factors of death in diabetic nephropathy hemodialysis patients. Results The follow-up time ranged from 16 to 54 months, with a median follow-up time of 30.5 months. At the end of follow-up, 52 of all cases survived and 43 cases died. Estimated glomerular filtration rate and total cholesterol levels of the dead patients were lower than those of the surviving patient and the proportion of C-reactive protein, low density lipoprotein, blood phosphorus, proportion of patients with coronary heart disease, and myocardial ischemia were higher than those of the surviving patients, with statistical significance (P ＜ 0.05). Multivariate analysis showed that high blood phosphorus, complicated with coronary heart disease and myocardial ischemia were independent risk factors for death in diabetic nephropathy patients on hemodialysis (HR ＞ 1, P ＜ 0.05). Conclusion During hemodialysis treatment for diabetic nephropathy patients, attention should be paid to the prevention of coronary heart disease and myocardial ischemia, and the reduction of blood phosphorus level.
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