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Study on the diagnostic value of ultra-high b-value DWI-IVIM combined with DCE-MRI in prostate cancer |
WANG Song XIA Jinxiang |
Medical Imaging Center, the Second People’s Hospital of Hefei, Anhui Province, Hefei 230011, China |
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Abstract Objective To investigate the diagnostic value of ultra-high multiple diffusion sensitivity coefficients (b-value) diffusion weighted imaging-intravoxel incoherent motion (DWI-IVIM) combined with dynamic contrast-enhancement magnetic resonance imaging (DCE-MRI) in prostate cancer. Methods The clinical data of 80 patients with suspected prostate cancer admitted to the Second People’s Hospital of Hefei from February 2017 to July 2020 were analyzed. The apparent diffusion coefficient (ADC) and f values of the central region, transitional region, and peripheral region of patients diagnosed by ultra-high b-value DWI-IVIM; volume conversion constant (Ktrans) and rate constant (Kep) values of prostate cancer focal area, hyperplastic area, and normal area were compared; pathological examination results were taken as the gold standard to compare the diagnostic efficacy of different methods. Results ADC values of central region, transitional region, and peripheral region of prostate cancer patients were lower than those of prostate hyperplasia patients, and f values were higher than those of prostate hyperplasia patients, and the differences were statistically significant (P < 0.05). There were significant differences in Ktrans and Kep values between prostate cancer focal area, hyperplasia area, and normal area (P < 0.05). The sensitivity and specificity of ultra-high b-value DWI-IVIM were 91.84% and 77.42% respectively; the sensitivity and specificity of DCE-MRI were 91.84% and 74.19% respectively; the sensitivity and specificity of the combined detection were 95.92% and 90.32% respectively. Conclusion Comparing with ultra-high b-value DWI-IVIM or DCE-MRI single detection, the sensitivity and specificity of combined detection are significantly increased, and has higher diagnostic efficacy for prostate cancer.
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[1] 叶定伟,顾成元,朱耀.NCCN前列腺癌临床治疗指南更新要点解读与探讨[J].中华泌尿外科杂志,2013,34(12):949-951.
[2] 曾俊杰,邓巧玲,李胜,等.高b值DWI联合DCE-MRI对前列腺癌的诊断价值[J].中国医刊,2018,53(8):911-915.
[3] 盛伟华,黄松,李烨,等.DCE-MRI定量参数联合ADC值诊断前列腺癌的价值及与血清PSA的相关性分析[J].川北医学院学报,2020,35(3):461-464.
[4] 李鹏,梁浩然.多弥散敏感系数DWI和DCE-MRI联合在前列腺癌及前列腺增生鉴别诊断的价值研究[J].河北医学,2019,25(2):193-197.
[5] 姚世文,蔡亚琴,倪建.DCE-MRI定量参数和ADC值对前列腺癌的临床诊断价值及ADC值与血清PSA、P504S的相关性[J].现代医学,2017,45(9):1266-1270.
[6] 冷晓明,韩晓蕊,徐嬿,等.IVIM-DWI和定量DCE-MRI鉴别前列腺癌和前列腺增生--灌注系数的相关性研究[J].影像诊断与介入放射学,2016,25(5):390-395.
[7] 葛建钢,陆健美,严佳,等.多模态磁共振成像技术诊断前列腺癌的多因素分析[J].新疆医科大学学报,2020,43(7):926-930.
[8] 王伟,黄兴鸿,丁偕,等.不同弥散加权成像对基于生成对抗网络的前列腺癌检测的影响[J].同济大学学报:医学版,2020,41(4):460-466.
[9] 牛磊,崔文,王明皓,等.多参数3.0T MRI在前列腺癌诊断中的应用研究[J].实用放射学杂志,2019,35(11):1848-1851.
[10] 陈芬,骆华春,傅志超,等.DWI对前列腺癌的诊断价值及ADC平均值与其危险程度的相关性分析[J].医疗卫生装备,2018,39(11):57-59,73.
[11] 陈丽华,刘爱连,郭妍,等.基于磁共振扩散加权图像的诺模图在前列腺癌与前列腺增生鉴别诊断中的应用及其诊断PI-RADS 4分中前列腺癌的可行性[J].中国临床医学影像杂志,2019,30(12):881-887.
[12] 尹雪军,刘林,牛富业,等.3.0T磁共振多b值DWI及动态增强在前列腺癌诊断中的价值[J].中国数字医学,2017,12(6):79-81,114.
[13] 吴慧,任建军,牛广明,等.IVIM鉴别前列腺癌、腺体型及基质型增生的价值研究[J].内蒙古医科大学学报,2017, 39(2):107-111.
[14] 杨莉月,耿承军,杨晓亮.MRI多参数成像技术在前列腺癌患者诊断中的应用[J].中国实验诊断学,2017,21(11):1907-1911.
[15] 王伟,邵志红,曾嘉齐,等.不同计算化高扩散敏感系数对外周带前列腺癌第二版前列腺影像和数据报告系统中弥散加权成像评分的影响[J].中华医学杂志,2017, 97(43):3401-3405.
[16] 温茹,赵文露,魏超刚,等.动态增强MRI和扩散加权成像定量参数直方图与前列腺癌Gleason评分的相关性[J].中华放射学杂志,2017,51(5):355-361.
[17] 马亚文,夏厚萍.3.0T磁共振扩散加权成像对老年前列腺癌与前列腺增生的鉴别诊断价值[J].安徽医学,2019, 40(5):493-495.
[18] Parra NA,Pollack A,Chinea FM,et al. Automatic Detection and Quantitative DCE-MRI Scoring of Prostate Cancer Aggressiveness [J]. Front Oncol,2017,7:259.
[19] 曾桔,印隆林,孙菊,等.不同b值组合的IVIM成像在前列腺癌诊断中的应用价值研究[J].临床放射学杂志,2020,39(7):1367-1372.
[20] Switlyk MD,Salberg UB,Geier OM,et al. PTEN Expression in Prostate Cancer:Relationship With Clinicopathologic Features and Multiparametric MRI Findings. AJR Am J Roentgenol [J]. 2019,19:1-9.
[21] Chatterjee A,He D,Fan X,et al. Performance of Ultrafast DCE-MRI for Diagnosis of Prostate Cancer [J]. Acad Radiol,2018,25(3):349-358.
[22] 仇菲,甄俊平,李嘉楠,等.超高b值DWI对前列腺癌诊断价值的Meta分析[J].中国CT和MRI杂志,2021, 19(3):113-117.
[23] Jambor I,Falagario U,Ratnani P,et al. Prediction of biochemical recurrence in prostate cancer patients who underwent prostatectomy using routine clinical prostate multiparametric MRI and decipher genomic score [J]. J Magn Reson Imaging,2020,51(4):1075-1085.
[24] 陆健美,葛建钢,王静,等.联合应用3.0T磁共振T2WI、DWI及DCE-MRI成像诊断前列腺癌[J].实用肿瘤杂志,2020,35(4):355-359.
[25] 田龙,闫洁诚,胡逸民.前列腺癌靶区位移影响因素分析[J].北京生物医学工程,2021,40(4):406-412.
[26] 廖玉平,黄文飞,唐庆健.磁共振扩散加权成像联合MR动态增强扫描在宫颈癌临床诊断中的价值分析[J].中国医药科学,2021,11(5):182-185.
[27] 蔡彩云,刘建成,陈文锦,等.肿瘤标志物联合多b值DWI MR多期动态增强成像对肝脏肿瘤的诊断价值[J].中国现代医生,2020,58(29):125-128.
[28] 贾媛,王海宝,余永强,等.DCE-MRI对前列腺平台型强化灶的鉴别诊断价值[J].临床放射学杂志,2016,35(4):589-592.
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