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2022 Vol. 19, No. 18 Published: 2022-06-25

	5	Visual analysis of domestic kinesio taping research based on CiteSpace
		SU Peng1 HU Shijing2 FU Junjie3 CHEN Ruiquan4 HU Yue1 ZHANG Tengfei1 HU Xin1 MENG Sijin5▲
		Objective To analyze the research status, research trend and evolution of research hotspots of kinesio taping in China in recent ten years, in order to provide some reference for future research. Methods Literatures related to kinesio taping from January 2011 to July 2021 were searched in China National Knowledge Infrastructure database. Co-occurrence analysis of authors and institutions was performed using CiteSpace software, and keywords co-occurrence analysis and cluster analysis were performed. Results A total of 608 literatures were included, involving 315 authors and 222 institutions. The overall annual number of literatures showed a steady trend with an increase. Chen Wenhua published the most literatures, and teamwork was the most intense. The main research institutions were “Department of Rehabilitation Medicine, the First People’s Hospital Affiliated to Shanghai Jiao Tong University”, “School of Sports Science, Shanghai University of Sport”, “School of International Medical Technology, Shanghai Shanda University” and other institutions. The main keywords were kinesio taping, stroke, shoulder-hand syndrome, etc., and there were ten categories of keyword clustering labels. The research focus was mainly on the application of stroke and rehabilitation therapy. Conclusion This study reveals that the domestic research on kinesio taping has been heating up in recent ten years, and the research direction shows a diversified trend. However, high-quality clinical practice research and in-depth and systematic basic research are needed to explore the effect and mechanism of kinesio taping.
		2022 Vol. 19 (18): 5-9,14 [Abstract] ( 126 ) HTML (1 KB) PDF (3253 KB) ( 163 )

	10	Discussion on the law of point selection and compatibility of acupuncture and moxibustion in the treatment of Ménière’s disease based on data mining technology
		SHI Yun1 DONG Yongshu2
		Objective To explore the law of point selection and compatibility of acupuncture and moxibustion in the treatment of Ménière’s disease (MD) by using data mining. Methods The clinical literatures of acupuncture and moxibustion in treatment of MD from China National Knowledge Infrastructure, Wanfang database and VIP database from inception to October 2021 were searched, and the acupuncture and moxibustion point prescription database was established. SPSS Statistics 26.0 and Rversion 3.6.1 were used for descriptive analysis, cluster analysis and association rule analysis. Results According to the analysis of the frequency of 142 acupuncture and moxibustion prescriptions, the point frequency analysis showed that bǎihuì, fēngchí, nèiguān, tàichōng, and zúsānlǐ were used more frequently; the most commonly used channels were the governor channel and gallbladder channel; the specific points were mainly crossing point. Cluster analysis results showed that points with frequency ≥15 could be grouped into four categories. Association rule analysis results showed that bǎihuì and fēngchí had the highest support degree, while nèiguān, zúsānlǐ, and fēnglóng had the highest promotion degree. Conclusion Through data mining technology, it is found that acupuncture and moxibustion in the treatment of MD has the characteristics of paying attention to local point selection, yang channel selection, crossing point selection, and remote point selection, which can provide some reference for clinical acupuncture and moxibustion point selection.
		2022 Vol. 19 (18): 10-14 [Abstract] ( 73 ) HTML (1 KB) PDF (1895 KB) ( 42 )

	15	Application of self-made needle guide in the treatment of type A2 femoral trochanteric fractures in the elderly patients with proximal femoral nail antirotating microtraumatic operation
		CHENG Houqing LI Jingguan ZHANG Jun WU Delin HUANG Yu
		Objective To evaluate the application of self-made needle guide in the treatment of type A2 femoral trochanteric fractures in the elderly patients with proximal femoral nail antirotating (PENA) microtraumatic operation. Methods A total of 62 elderly patients with type A2 femoral trochanteric fracture admitted to Wuhu Hospital of Traditional Chinese Medicine, Anhui Province (hereinafter referred to as “our hospital”), from February 2019 to June 2020 were selected and divided into observation group (31 cases) and control group (31 cases) by computer random method. The observation group received PFNA microtraumatic operation, and the our hospital self-made PFNA needle guide was used in the operation. The control group received conventional PFNA operation. Operation time, intraoperative blood loss, operative incision, reduction quality, and Harris, daily living activity (ADL) scores at 1, 3, and 12 months after operation were compared between the two groups, and the incidence of adverse reactions between the two groups was recorded. Results The operation time and incision of the observation group were shorter than those of the control group, and the amount of intraoperative blood loss was lower than that of the control group, the differences were statistically significant (P ＜ 0.05). There was no significant difference in reduction quality between the two groups (P ＞ 0.05). Harris and ADL scores of the two groups at 12 months after operation were higher than those at one and three months after operation, the differences were statistically significant (P ＜ 0.05). The Harris and ADL scores of the observation group one month after operation were higher than those of the control group at the same time, the differences were statistically significant (P ＜ 0.05). There was no significant difference in numbers of postoperative retransfusion between the two groups (P ＞ 0.05). Conclusion Self-made needle guide in PFNA microtraumatic operation for the treatment of elderly patients with femoral trochanteric fractures can be quickly and accurately injected, reduce the operation time, intraoperative blood loss, shorten the surgical incision, postoperative hip function recovery, and daily living activities of satisfactory recovery, worthy of clinical promotion, and application.
		2022 Vol. 19 (18): 15-19 [Abstract] ( 109 ) HTML (1 KB) PDF (1212 KB) ( 57 )

	20	Study on the correlation between osteoporosis and carotid atherosclerosis in elderly men with diabetes mellitus
		SHI Li1 REN Weidong1 WANG Likun2 LI Chaoxi2 ZHANG Zhiying1 DENG Wenjuan1 HU Limei1 ZUO Lijuan1
		Objective To investigate the relationship between osteoporosis and carotid atherosclerosis in elderly male diabete mellitus patients in Zhangjiakou region, and to provide more scientific basis for the prevention and treatment of osteoporosis and arteriosclerosis. Methods A total of 100 elderly male patients with type 2 diabetes mellitus who were treated in the Department of Neurology, the First Affiliated Hospital of Hebei North University from September 2017 to September 2019 were selected. The age, body mass index, course of diabetes, hypertension, smoking, alcohol consumption, insulin application history, and related information were collected. The femoral neck bone mineral density and carotid intima-media thickness (IMT) were measured, and 100 patients were divided into carotid atherosclerosis group (66 cases) and non-atherosclerosis group (34 cases) according to relevant standards. The differences in clinical characteristics of the two groups were compared, and the correlation between bone mineral density and IMT was analyzed. Results There were significant differences in age, total cholesterol, triglyceride, low-density lipoprotein cholesterol, fasting blood glucose, glycosylated hemoglobin levels, and bone mineral density of femoral neck between the two groups, and the differences were statistically significant (P ＜ 0.05). The incidence of osteoporosis in the carotid atherosclerosis group was higher than that in the non-atherosclerosis group, and the difference was statistically significant (P < 0.05). Bone mineral density values were negatively correlated with carotid IMT values (r = -0.605, P < 0.05). Conclusion Aging, hyperglycemia, hyperlipidemia and other factors can affect carotid atherosclerosis in elderly male diabetes mellitus patients, and there is a significant correlation between osteoporosis and carotid atherosclerosis. Therefore, while preventing carotid atherosclerosis, it is necessary to pay close attention to the occurrence of osteoporosis, so as to reduce the risk of fracture.
		2022 Vol. 19 (18): 20-23 [Abstract] ( 108 ) HTML (1 KB) PDF (894 KB) ( 41 )

	24	Effect of inhibition of Rictor on myocardial autophagy in sepsis mice
		JIANG Wanwei YANG Guohui
		Objective To study the effect of inhibition Rictor on myocardial autophagy in sepsis mice. Methods A total of 36 healthy male SPF Kunming mice were divided into sham operation group, model group, and experimental group according to the random number table method, with 12 mice in each group. The animal model of sepsis was established by cecal ligation and puncture. The experimental group was given 10 mg/kg intraperitoneal injection of Rictor-specific inhibitor JR-AB2-011, the sham operation group and model group were given the same amount of normal saline. Abdominal aortic blood was collected from six mice in each group at 12 and 24 h postoperatively, and the levels of serum cardiac troponin I (cTnI) and creatine kinase MB (CK-MB) were detected. The expression changes of Rictor, Akt, Raptor, and LC3B in mouse myocardial tissue were detected; the pathological changes of myocardial tissue were observed by transmission electron microscope and HE staining. Results In model group, cTnI, CK-MB, Rictor, Phospho-Aktser473, and Raptor at each time point were higher than those in sham operation group (P < 0.05). In the experimental group, cTnI, CK-MB, Rictor, Phospho-Aktser473, and Raptor at each time point were lower than those in model group, and LC3B were higher than that in model group (P < 0.05). The myocardial fibers of the sham operation group was normal; moderate watery degeneration of myocardial fibers can be seen in model group; a small amount of myocardial fibers showed watery degeneration and cell swelling in experimental group. Autophagosomes and autophagy lysozyme could be observed in model group and experimental group. Conclusion Inhibition Rictor can enhance autophagy of myocardial cells in sepsis mice and reduce cell damage.
		2022 Vol. 19 (18): 24-26,32 [Abstract] ( 71 ) HTML (1 KB) PDF (1139 KB) ( 53 )

	27	Efficacy study of “Knee six fixed-point” “knee seven fixed-point” acupotomy on knee osteoarthritis in early and middle stage
		FANG Lina LI Shangfeng YUAN Hongli ZHOU Yu
		Objective To observe clinical effect of “knee six fixed-point” “knee seven fixed-point” acupotomy on knee osteoarthritis in early and middle stage. Methods From February 2020 to June 2021, seventy cases of KOA patients in the outpatient and ward of Department of Acupuncture and Massage and Department of Rheumatology of the First Affiliated Hospital of Xinjiang Medical University were selected as the research objects. They were divided into control group and treatment group according to random number table method. The control group (35 patients) were treated with Western medicine and traditional Chinese herb external medicinal liquid application, the treatment group (35 cases) was treated with Western medicine and traditional Chinese herb external medicinal liquid application combined with acupotomy therapy, acupotomy therapy once a week. Short form McGill pain questionnaire (including pain sensation, pain emotion, visual analogue scale [VAS], and present pain intensity [PPI]) scores, knee range of motion, index severity of knee arthritis (ISOA) scores, and clinical efficacy before and after treatment were observed after three weeks. Results After treatment, the pain sensation, pain emotion, VAS, and PPI scores in two groups were lower than those before treatment, and those in the treatment group were lower than those in the control group, the differences were statistically significant (P ＜ 0.05). After treatment, the knee bend scores of the two groups were higher than those before treatment, the knee extension scores of the two groups were lower than those before treatment, and the knee bend score of the treatment group was higher than that of the control group, while the knee extension score of the treatment group was lower than that of the control group, the differences were statistically significant (P ＜ 0.05). After treatment, ISOA scores of the two groups were higher than those before treatment, and that in the treatment group was higher than that in the control group, the differences were statistically significant (P ＜ 0.05). The clinical efficacy of the treatment group was better than that of the control group, and the difference was statistically significant (P ＜ 0.05). Conclusion The effect of “knee six fixed-point” and “knee seven fixed-point” acupotomy is certain, it can improve pathological pain in early and middle KOA patients, help restore joint function and improve clinical efficacy.
		2022 Vol. 19 (18): 27-32 [Abstract] ( 97 ) HTML (1 KB) PDF (1360 KB) ( 36 )

	33	Visual analysis of the current situation and future approach of postgraduate education of Chinese medicine based on CNKI
		FANG Xiaoyan KANG Le ZHU Zhijun WANG Can BAI Li MIAO Mingsan
		Objective To visually analyze the method of bibliometrics, this paper makes a visual analysis of the literatures of Chinese medicine graduate education in China, and discusses the research status and future direction of this field in the past 20 years. Methods Chinese medicine postgraduate education literatures from January 2000 to December 2020 were searched in CNKI, and CiteSpace software and bibliometric method were used for visual analysis from the number of annual publications, authors, research institutions, keywords, and other aspects. Results A total of 850 articles were included, in 2014, the number of articles was the largest, from 2015 to 2020, it was in a relatively stable stage; there were 17 core authors. The top one issuing unit was Beijing University of Chinese Medicine, next was Guangzhou University of Chinese Medicine; before 2018, high-frequency keywords focused on education, teaching, discipline, and curriculum construction, training mode, etc., and after 2018, internationalization, one belt one road, ideological and political education were the high-frequency keywords. Conclusion In the past 20 years, the research on postgraduates of Chinese medicine has focused on the fields of education, teaching, discipline and curriculum construction, training mode, etc. The future research may tend to ideological and political education and the training mode under the background of internationalization.
		2022 Vol. 19 (18): 33-37 [Abstract] ( 93 ) HTML (1 KB) PDF (2364 KB) ( 40 )

	38	Research progress on the mechanism of traditional Chinese medicine treatment of depression complicated with coronary heart disease based on cell pyroptosis
		LI Lanshi1 WANG Ying2
		Depression and coronary heart disease are both chronic inflammatory diseases, the harms of inflammatory responses in the occurrence and development of the two diseases have been recognized. It was found that the rates of incidence and mortality of coronary heart in depression patients were increasing day by day. Recently studies had found that depression caused a variety of individual brain cells pyroptosis especially the microglia pyroptosis, it could promote the highly pro-inflammatory programmed cell death mode. And the cascaded inflammation responces caused by pyroptosis in the brain are an important molecular mechanism that may induces vascular endothelial injurying, atherosclerosis, and ultimately coronary heart disease for depressed patients. At the same time, a large number of cells, animals, and clinical experiments had proved that a variety of traditional Chinese medicine could treat depression combined with coronary heart disease by regulating the expression of various proteins about pyroptosis, and the curative effect was significant. This paper intends to sort out the specific mechanism of traditional Chinese medicine action from the perspective of cell pyroptosis, hoping to provide new ideas and possibilities for clinical prevention and treatment of depression complicated with coronary heart disease.
		2022 Vol. 19 (18): 38-41 [Abstract] ( 67 ) HTML (1 KB) PDF (508 KB) ( 52 )

	42	Progress in the study of the effect of sodium-glucose linked transporter-2 inhibitor on blood uric acid in patients with type 2 diabetes mellitus
		LI Xiaoe1 PANG Juanjuan1 ZHANG Zunlei2 LI Yuting1
		Blood uric acid (UA) metabolism is in dynamic balance in normal human body, and its abnormal concentration is not conducive to health. Sodium-glucose linked transporter-2 inhibitor (SGLT-2i) is a novel hypoglycemic drug that has been marketed in recent years, which can improve various symptoms of type 2 diabetes mellitus patients. In addition to the hypoglycemic effect of SGLT-2i itself, this effect may be related to the improvement of blood UA metabolism in type 2 diabetes mellitus patients. This article intends to explain the pathophysiological effects of blood UA and the mechanism of the effect of SGLT-2i on blood UA in patients with type 2 diabetes mellitus, in order to have a better understanding of SGLT-2i.
		2022 Vol. 19 (18): 42-45 [Abstract] ( 94 ) HTML (1 KB) PDF (606 KB) ( 56 )

	46	Analysis of job satisfaction and influencing factors of primary medical staff based on two-factor theory
		WU Rong1 LU Tingting1 HU Dan2 ZHU Jing3
		Objective To understand the status quo of job satisfaction among primary medical staff, and to analyze its influencing factors based on the two-factor theory. Methods In July 2020, the job satisfaction information of 428 primary medical staff in Pukou District, Nanjing City was collected through a questionnaire survey, and quantitative analysis was carried out. Results There were statistically significant differences in the scores of different ages, positions, training frequency, the availability of alternative jobs, and the satisfaction scores of health care factors (P ＜ 0.05); there were statistically significant differences in the satisfaction scores of motivational factors among different age, educational background, position, working time, training frequency, and alternative job availability (P ＜ 0.05). Logistic regression analysis showed that job title (OR = 2.59, 95%CI: 1.33-5.04), training frequency (OR = 1.31, 95%CI: 1.09-1.58), and alternative job availability (OR = 4.11, 95%CI: 2.84-5.94) were the influencing factors of health factor satisfaction (P ＜ 0.05); job title (OR = 1.77, 95%CI: 1.04-3.01), training frequency (OR = 1.51, 95%CI: 1.27-1.79), and alternative job availability (OR = 1.93, 95%CI: 1.41-2.65) were influencing factors of motivation factor satisfaction (P ＜ 0.05). Conclusion By constructing a multi-level old-age security system and giving play to the role of material and spiritual rewards in performance incentives, the job satisfaction of primary medical staff can be effectively improved.
		2022 Vol. 19 (18): 46-50 [Abstract] ( 78 ) HTML (1 KB) PDF (612 KB) ( 190 )

	51	Investigation and analysis on the current situation of patent application and common sense of medical staff in a hospital affiliated to a university in Jiangsu Province
		CHEN Fei XU Shuizhu PAN Lingling SHI Wei SHAO Mingbing▲
		Objective To understand the current situation of patent application and patent knowledge of medical staff in the Affiliated Hospital of Nantong University (hereinafter referred to as “our hospital”), to provide reference for the formulation and adjustment of patent management policies in our hospital in the future. Methods In May 2020, the convenience sampling method was adopted, and a questionnaire was designed on the basis of reading and references to investigate and analyze the current situation of patent application and the mastery of relevant patent knowledge of medical staff in our hospital. Results A total of 410 questionnaires were distributed in this study, and 408 valid questionnaires were recovered, with an effective recovery rate of 99.5%. In this survey, only 125 medical staff had applied for patents, accounted for 30.6%. The main reason for not applying was that there were no projects to apply for patents. Among them, 105 patents had been authorized, mainly utility model patents, 81 patents were in maintenance, four patents had lost the protection of the patent rights and terminated, and only one patent had been transferred. Only 69 people (16.9%) had some understanding of the basic knowledge of patents and application procedures, and 339 people (83.1%) had no basic knowledge. There were statistically significant differences in the proportion of medical staff in different professional and technical fields and professional titles (P ＜ 0.05). Comparing the proportions of medical staff with different professional and technical fields, educational backgrounds, professional titles, and whether they had applied for patents before on the basic knowledge of patents and the degree of understanding of the application procedures, and the differences were highly statistically significant (P ＜ 0.01). The multivariate logistic regression results showed that senior professional titles (OR[95%CI]: 5.19[2.36-11.42]), medical staff who knew the protection period of patent application (OR[95%CI]: 9.92[4.75-20.70]), utility model and design patent right answered correctly (OR[95%CI]: 2.36[1.33-4.20]) were the influencing factors of patent application (P ＜ 0.05). Conclusion The patent application rate of medical staff in our hospital is low, and the patent knowledge is insufficient. Hospitals should attach importance to patent management, explore and cultivate high-value patents, strengthen the training and popularization of patent knowledge, improve the incentive mechanism, mobilize the enthusiasm for patent creation and application, and use the concept of total quality management to improve the quality and conversion rate of patent applications.
		2022 Vol. 19 (18): 51-54,70 [Abstract] ( 72 ) HTML (1 KB) PDF (671 KB) ( 35 )

	55	Influencing factors of postoperative sexual dysfunction in patients with pelvic organ prolapse with normal preoperative female sexual function
		YIN Huali HUANG Aihua WANG Fei
		Objective To investigate the influencing factors of postoperative female sexual dysfunction (FSD) with pelvic organ prolapse (POP) with normal preoperative sexual function. Methods The clinical data of 139 patients who underwent POP surgery and had normal preoperative sexual function from December 2019 to December 2020 in Taizhou People’s Hospital were retrospectively analyzed. Six months after the operation, according to the female sexual function inventory (FSFI), the patients were divided into FSD group (FSFI＜26.55 points, 43 cases) and no FSD group (FSFI≥26.55 points, 96 cases). Basic data of two groups were collected, and the risk factors of FSD after POP were clearly analyzed. Results The proportion of patients age ＞40 years, obesity, junior high school education or below, monthly income level ＜6000 yuan, delivery times ≥ three times, menopause, pelvic floor type Ⅰ muscle fiber muscle strength ≤ grade three, pelvic floor type Ⅱ muscle fiber muscle strength ≤ grade three patients in the FSD group were higher than those in the non-FSD group, and the differences were statistically significant (P ＜ 0.05). Multivariate logistic regression analysis showed that age ＞40 years (OR = 1.123), obesity (OR = 1.131), junior high school education (OR = 1.245), monthly income level ＜6000 yuan (OR = 1.316), delivery times ≥ three times (OR = 1.219), menopause (OR = 2.894), pelvic floor type Ⅰ muscle fiber muscle strength ≤ grade three (OR = 1.654), pelvic floor type Ⅱ muscle fiber muscle strength ≤ grade three (OR = 1.231) were influencing factors for FSD after POP surgery (P ＜ 0.05). Conclusion There are many influencing factors of FSD after POP surgery in women, which should be paid attention to.
		2022 Vol. 19 (18): 55-58 [Abstract] ( 78 ) HTML (1 KB) PDF (548 KB) ( 61 )

	59	Correlation analysis between occupational musculoskeletal disorders of ICU nurses and nurses’ practice environment
		ZHENG Shuangfeng1 JIANG Xin2 LEI Wen2 CHE Yajie2 LI Yinglan2 YAN Ping2
		Objective To understand the current status of work-related musculoskeletal diseases (WMSDs) among intensive care unit (ICU) nurses and to analyze their relationship with the nurse practice environment. Methods A random cluster sampling method was used to conduct a questionnaire survey among ICU nurses in the First Affiliated Hospital of Xinjiang Medical University from January to March 2021 by using a general demographic questionnaire, a Chinese musculoskeletal disorder questionnaire, and a nurse practice environment questionnaire. Results A total of 170 questionnaires were distributed in this study, and 158 qualified questionnaires were recovered, with an effective recovery rate of 92.94%. In 2021, the annual prevalence of WMSDs among ICU nurses was 72.78%, with a total of 115 cases. Among them, the prevalence rates of waist, neck, and shoulder were ranked the top three, which were 53.16%, 43.04%, and 41.14%, respectively. The scores of hospital management participation, clinical nursing professionalism, leadership and communication, quality management, internal support, professional improvement, and social status in the WMSDs group were lower than those in the non-WMSDs group, with statistically significant differences (P ＜ 0.05); there were no statistically significant differences in the scores of cooperation, manpower allocation, and remuneration (P ＞ 0.05). The results of Pearson correlation analysis showed that the occurrence of WMSDs among ICU nurses was related to hospital management participation (r = -0.167), clinical nursing professionalism (r = -0.183), leadership and communication (r = -0.181), quality management (r = -0.196), internal support (r = -0.162), professional advancement (r = -0.181), and social status (r = -0.215) were negatively correlated (P ＜ 0.05). Conclusion The incidence of WMSDs in ICU nurses is high, and the nurse practice environment may have a comprehensive impact on the occurrence of WMSDs, and further investigation is needed to investigate the mechanism of how it affects WMSDs.
		2022 Vol. 19 (18): 59-62 [Abstract] ( 75 ) HTML (1 KB) PDF (532 KB) ( 37 )

	63	Changes of serum Lp-PLA2, IL-18, and S100A8 levels in patients with type 2 diabetes mellitus and their relationship with diabetic foot ulcers
		CHEN Hongyan LONG Ke HUANG Shuying MIN Shan
		Objective To analyze the relationship between serum lipoprotein associated phospholipase A2 (Lp-PLA2), interleukin (IL)-18, calcin binding protein S100A8 (S100A8) and diabetic foot ulcers (DFU). Methods The clinical data of 183 patients with type 2 diabetes mellitus (T2DM) who were followed up in Panyu Hospital of Chinese Medicine from January 2019 to March 2021 were collected and they were divided into T2DM group (101 cases) and DFU group (82 cases) according to whether they were complicated with DFU. The differences of general clinical data, Lp-PLA2, IL-18, S100A8, and other biochemical indexes between the two groups were compared, and the risk factors of DFU were discussed. Results Fasting blood glucose and glycosylated hemoglobin levels in the DFU group were higher than those in the T2DM group, and diabetes duration in DFU group was longer than the T2DM group (P ＜ 0.05). Lp-PLA2, IL-18, S100A8, C-reactive protein, IL-1β, tumor necrosis factor-α, white blood cell count, and the proportion of neutrophils in DFU group were higher than those in T2DM group (P ＜ 0.05). Logistic regression analysis showed that, the increase of IL-1β (OR = 1.766, 95%CI：1.332-2.343, P ＜ 0.001), Lp-PLA2 (OR = 1.824, 95%CI：1.294-2.571, P ＜ 0.001), IL-18(OR = 2.083, 95%CI：1.367-3.175, P ＜ 0.001), S100A8(OR = 1.941, 95%CI：1.211-3.112, P ＜ 0.001) were all risk factors for DFU. Conclusion The increase of serum Lp-PLA2, IL-18, and S100A8 levels is closely related to the pathogenesis of DFU, which can be used for early prevention, diagnosis and treatment of high-risk DFU patients.
		2022 Vol. 19 (18): 63-66,74 [Abstract] ( 68 ) HTML (1 KB) PDF (709 KB) ( 31 )

	67	Changes of 25-hydroxyvitamin D and its related indexes in patients with early diabetic nephropathy
		LAN Kai LIU Haoang LIU Shuyi ZHANG Xudong ZHANG Guangwei
		Objective To observe the changes of serum 25-hydroxyvitamin D, Interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α) and urinary albumin creatinine ratio (UACR) in patients with early diabetic nephropathy (DN). Methods A total of 67 patients with early DN who were hospitalized in the Department of Nephrology, the First Affiliated Hospital of Xian Medical University from September to December 2020 were selected as DN group. A total of 74 healthy individuals who underwent physical examination in the First Affiliated Hospital of Xian Medical University during the same period were selected as the control group. The height, body mass index, and blood pressure of each group were collected, and the levels of fasting 25-hydroxyvitamin D, IL-1β and TNF-α, UACR and glucose and lipid metabolism indexes were measured; the relationship between vitamin D and IL-1β, TNF-α, TC, TG, and UACR were analyzed. Results The levels of body mass index, fasting blood glucose and glycosylated hemoglobin in DN group were higher than those in control group, and the differences were statistically significant (P ＜ 0.05). TC, TG, LDL-C and UACR levels in DN group were higher than those in control group, while HDL-C level was lower than control group, the differences were statistically significant (P ＜ 0.05). The level of 25-vitamin D in DN group was lower than that in control group, the difference was statistically significant (P ＜ 0.05). The levels of IL-1β and TNF-α in DN group were higher than those in control group, and the differences were statistically significant (P ＜ 0.05). There was negative correlation between serum 25-hydroxyvitamin D levels and IL-1β, TNF-α level and UACR in DN group (r = -0.647, -0.783, -1.621, P ＜ 0.05). Conclusion The serum 25-hydroxyvitamin D level in patients with early DN is lower than that in normal person, and its level is correlated with inflammatory factors, proteinuria and other risk factors.
		2022 Vol. 19 (18): 67-70 [Abstract] ( 103 ) HTML (1 KB) PDF (533 KB) ( 20 )

	71	Analysis of the influencing factors of benign prostatic hyperplasia complicated with lower urinary tract symptoms
		XU Yunfeng1 YOU Zhixin1 LI Yilei1 QIU Feng2▲
		Objective To analyze the influencing factors of benign prostatic hyperplasia complicated with lower urinary tract symptoms. Methods The clinical data of patients admitted to the First Affiliated Hospital of Soochow University from May 2018 to April 2020 which were included 124 patients with benign prostatic hyperplasia complicated with lower urinary tract symptoms (study group) and 133 patients with benign prostatic hyperplasia without lower urinary tract symptoms (control group) were retrospectively analyzed. Using the international prostate symptom score (IPSS), the patients in the study group were recorded as mild group (48 cases, IPSS 0-7 points), moderate group (54 cases, IPSS 8-19 points), and severe group (22 cases, IPSS 20-35 points) according to the severity of the disease. Logistic regression analysis was used to explore the influencing factors of severe lower urinary tract symptoms in patients with benign prostatic hyperplasia. Results The systolic blood pressure, diastolic blood pressure, body mass index (BMI), prostate volume (PV), and fasting blood glucose (FBG) in the study group were higher than those in the control group, while waist circumference and hip circumference were lower than those in the control group, and the differences were highly statistically significant (P ＜ 0.01). There were highly statistically significant differences in BMI, waist-to-hip ratio (WHR), and PV among the three groups (P ＜ 0.05). Further pairwise comparison showed that the severe group had higher BMI, WHR, and PV than those of the mild and moderate groups, and the differences were statistically significant (P ＜ 0.05); the BMI, WHR, and PV of the moderate group were higher than those of the mild group, and the differences were statistically significant (P ＜ 0.05). The levels of WHR, PV, and BMI in the severe group were higher than those in the mild-moderate group, while the proportion of combined lower urinary tract infection was higher than that in the mild-moderate group, and the differences were statistically significant (P ＜ 0.05). Logistic multivariate regression analysis showed that WHR (OR = 3.077), PV (OR = 3.838), and BMI (OR = 2.724) were the influencing factors of severe lower urinary tract symptoms in patients with benign prostatic hyperplasia (P ＜ 0.05). Conclusion WHR, PV, and BMI are risk factors for patients with benign prostatic hyperplasia complicated with lower urinary tract symptoms.
		2022 Vol. 19 (18): 71-74 [Abstract] ( 65 ) HTML (1 KB) PDF (552 KB) ( 33 )

	75	Effect of Bushen Tongbi Decoction on lumbar disc herniation
		ZHANG Yifan LI Qing ZHANG Qiuyuan
		Objective To study the clinical effect of Bushen Tongbi Decoction on lumbar disc herniation. Methods Eighty patients with lumbar disc herniation treated in Shijiazhuang People’s Hospital from January 2019 to January 2020 were selected. They were divided into control group and observation group by random number table method, with 40 cases in each group. The control group was treated with Diclofenac Sodium Double Release Enteric Coated Capsules, the observation group was treated with oral Bushen Tongbi Decoction on the basis of the control group. Both groups were treated for 21 days. The clinical efficacy and the changes of dysfunction, pain score, and inflammatory factors before and after treatment were compared between the two groups. Results The curative effect of observation group was better than control group (P ＜ 0.05). After treatment, the visual analogue scales and Oswestry disability index scores in both groups were lower than those before the treatment, and the observation group was lower than the control group (P ＜ 0.05). After treatment, the Japanese orthopaedic association evaluation scores of the two groups were higher than those before the treatment, and the observation group was higher than the control group (P ＜ 0.05). After treatment, the levels of hypersensitive C-reactive protein, interleukin-6, and tumor necrosis factor-α in two groups were lower than those before the treatment, and the observation group was lower than the control group (P ＜ 0.05). Conclusion Bushen Tongbi Decoction can effectively improve the clinical pain and dysfunction of lumbar disc herniation, and can effectively reduce the inflammation of the body, and it is werthy of clinical value.
		2022 Vol. 19 (18): 75-77,89 [Abstract] ( 110 ) HTML (1 KB) PDF (624 KB) ( 21 )

	78	Effects of different timings of cesarean section on the stress response and delivery risk of scarred uterus re-pregnancy
		CHU Zhenhao QIAO Chong
		Objective To investigate the effects of different cesarean section operation timings on stress response and delivery risk of scarred uterus re-pregnancy. Methods The clinical data of 105 cases of re-pregnant women with scarred uterus admitted to Shengjing Hospital of China Medical University from May 2017 to May 2020 were selected, according to the different operation timings of elective cesarean section, they were divided into 37 weeks ≤gestational week <39 weeks group (group A, 50 cases) and gestational age ≥39 weeks group (group B, 55 cases). The stress state before delivery and 24 h after delivery, complication rate, and pregnancy outcome of two groups were compared. Results The levels of aldosterone (ALD) and cortisol (Cor) in both groups 24 h were higher than those before delivery, and the level of norepinephrine (NA) in group A was higher than that before delivery, and the differences were statistically significant (P < 0.05). The levels of ALD, NA, and Cor in group B 24 h after delivery were lower than those in group A, and the differences were statistically significant (P < 0.05). The total incidence complication of group B was lower than that of group A, and the difference was statistically significant (P < 0.05). The amount of postpartum blood loss in group B was less than that in group A, the length of hospitalization was shorter than that in group A, and the Apgar score of newborn was higher than that in group A, and the differences were statistically significant (P < 0.05). There was no significant difference in neonatal weight between two groups (P > 0.05). There was no neonatal death in both groups. The incidence of neonatal respiratory diseases in group B was lower than that in group A, and the difference was statistically significant (P < 0.05); there was no significant difference in puerperal infection rate between two groups (P > 0.05). Conclusion Cesarean section can not only reduce stress response, but also reduce the incidence of complications and achieve better pregnancy outcomes for women with scarred uterus re-pregnancy over 39 weeks of gestation.
		2022 Vol. 19 (18): 78-81 [Abstract] ( 65 ) HTML (1 KB) PDF (572 KB) ( 34 )

	82	Predictive value of serum MMP-9 and TIMP-1 levels for intrauterine adhesions after early missed abortion
		SHI Fan GAO Yuan WU Xiaoyan YANG Wen▲
		Objective To explore the predictive value of serum matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1) levels for intrauterine adhesions after early missed abortion. Methods The general data of 92 patients with early missed abortion admitted to the First People’s Hospital of Lianyungang, Jiangsu Province from October 2019 to July 2021 were analyzed. The incidence of intrauterine adhesions in patients with early missed abortion one month after operation was counted, and according to whether intrauterine adhesions occurred, they were divided into occurrence group and non-occurring group. The risk factors for intrauterine adhesions after early missed abortion were analyzed, the receiver operating characteristic curve was drawn, and the predictive value of serum MMP-9 and TIMP-1 for intrauterine adhesions after early missed abortion was evaluated. Results The incidence of intrauterine adhesions one month after operation was 35.87%. The number of induced abortions, the number of uterine cavity operations in occurrence group were more than those in non-occurring group; tumor necrosis factor-α (TNF-α), interleukin-17 (IL-17), IL-35, MMP-9, and TIMP -1 levels in occurrence group were higher than those in non-occurring group (P < 0.05). The number of induced abortions, the number of uterine cavity operations, serum MMP-9, and TIMP-1 were risk factors for intrauterine adhesions after early missed abortion (OR ＞ 1, P < 0.05). The specificity and area under the curve of serum MMP-9 and TIMP-1 in predicting intrauterine adhesions after early missed abortion was higher than predicted alone (P < 0.05). Conclusion Serum MMP-9 and TIMP-1 levels have a high predictive value for intrauterine adhesions after early missed abortion, and can be used as important reference indicators for clinical evaluation.
		2022 Vol. 19 (18): 82-85 [Abstract] ( 65 ) HTML (1 KB) PDF (654 KB) ( 31 )

	86	Effect of nutritional support on children with acute lymphoblastic leukemia based on data standardized processing analysis of nutritional status
		PAN kexiang1 WANG Zhengmei2 LI Guangzhen1 ZHOU Yue1 MAO Lili1▲
		Objective To analyze the effect of nutritional support on children with acute lymphoblastic leukemia (ALL) based on data standardized processing analysis of nutritional status. Methods A total of 60 children with ALL were selected from the Affiliated Huaian NO.1 People’s Hospital of Nanjing Medical University from January 2018 to December 2020 were selected, they were divided into study group and control group by random number table method, with 30 cases in each group. The control group was given nutritional support according to 2018 ESPEN Critical Clinical Nutrition Guidelines, while study group was given nutritional support based on data standardized processing analysis of nutritional status. The nutritional status and physical indicators of two groups were compared on admission and at 20 d of nutritional support, and the infection status was counted at 20 d of nutritional support. Results At 20 d of nutritional support, serum albumin and serum prealbumin in both groups were higher than those on admission, and study group was higher than control group, and the differences were statistically significant (P < 0.05). The upper arm circumference of two groups was higher than that on admission, and study group was higher than control group, and the differences were statistically significant (P < 0.05). The triceps skin fold thickness of study group was higher than that on admission, and the difference was statistically significant (P < 0.05). The incidence of respiratory tract infection, oral infection, perianal infection, and lung infection in study group was lower than that in control group, and the difference was statistically significant (P < 0.05). Conclusion Nutritional support based on data standardized processing analysis of nutritional status can correct malnutrition and control the incidence of infection.
		2022 Vol. 19 (18): 86-89 [Abstract] ( 72 ) HTML (1 KB) PDF (584 KB) ( 23 )

	90	Prognostic value of serum copeptin combined with Marshall CT classification in infants with craniocerebral trauma
		YU Xiongwu1 LI Shifu2 DING Zhiyong3 XIONG Liangjun1 LI Chuanfeng4 LI Caifen5 WANG Chaohong5 DONG Yun1
		Objective To explore the prognostic value of serum copeptin combined with Marshall CT classification in infants with craniocerebral trauma. Methods A total of 110 children with craniocerebral trauma treated in Qujing Maternal and Child Health Hospital from February 2018 to June 2020 were selected, they were divided into survival group and death group according to the living condition of 28 days in hospital. The level of serum copeptin were measured between two groups, and the degree of trauma was evaluated by Marshall CT grading. The factors affecting the prognosis of infant craniocerebral trauma and the value of copeptin combined with Marshall CT classification in predicting the prognosis of infant craniocerebral trauma were analyzed. Results There were statistically significant differences in injury type, blood loss, and Glasgow coma scale score between two groups (P < 0.05). The serum copeptin levels and Marshall CT scores of death group were higher than those of survival group, and the differences were statistically significant (P < 0.05). Copeptin and Marshall CT score were influential factors of infant death after traumatic brain injury (OR > 1, P < 0.05). The area under the curve predicted by copeptin combined with Marshall CT score was higher than that predicted by copeptin and Marshall CT score alone (P < 0.05). Conclusion Copeptin and Marshall CT classification have certain value in predicting the prognosis of infant craniocerebral trauma. The combination of two indexes can improve the prediction efficiency.
		2022 Vol. 19 (18): 90-93 [Abstract] ( 68 ) HTML (1 KB) PDF (777 KB) ( 28 )

	94	Clinical study on the treatment of severe complex trichiasis of upper eyelid with pedicle orbicularis oculi muscle bridge flap transfer
		MIAO Sheng XU Xuedong CAO Li
		Objective To explore the clinical effect of pedicled orbicularis oculi muscle bridge flap transfer in the treatment of severe complex trichiasis of upper eyelid. Methods A total of 76 patients (76 eyes) with severe complex trichiasis of upper eyelid admitted to the Jiangyin People’s Hospital, Jiangsu Province from October 2018 to October 2020 were selected as the research subjects, and they were divided into the study group (38 cases, 38 eyes) and the control group (38 cases, 38 eyes) according to the random number table method. The control group was treated with conventional wedge surgery, and the study group was treated with pedicled orbicularis oculi muscle bridge flap transfer. The operation time, hospital stay, best corrected visual acuity before and two weeks after operation, daily living ability, appearance aesthetic, and postoperative comfort scores before and six months after operation, and recurrence rate and complication rate six months after operation were compared. Results There were no significant differences in operation time and hospital stay between the two groups (P > 0.05). Two weeks after operation, the best corrected visual acuity in both groups were lower than those before operation, and that in the study group was lower than that in the control group, the differences were statistically significant (P ＜ 0.05). Six months after operation, there was no statistically significant difference in the scores of daily living ability between the two groups (P ＞ 0.05), appearance aesthetic and comfort scores of the two groups were higher than those before surgery, and those in the study group were higher than those in the control group, the differences were statistically significant (P ＜ 0.05). Six months after surgery, there was no significant difference in recurrence rate between the two groups (P ＞ 0.05), and the incidence of complications in the study group was lower than that in the control group, the difference was statistically significant (P ＜ 0.05). Conclusion Pedicled orbicularis oculi muscle bridge flap transfer in the treatment of patients with severe complex trichiasis of upper eyelid can improve the repair effect, improve the aesthetics, and reduce the incidence of complications.
		2022 Vol. 19 (18): 94-97 [Abstract] ( 60 ) HTML (1 KB) PDF (521 KB) ( 24 )

	98	Visual analysis of literature on traditional Chinese medicine in the treatment of chronic gastritis in recent ten years
		LONG Yuanxiong1 XU Ying2 DENG Guiming1
		Objective To use CiteSpace software to visually analyze the literatures about traditional Chinese medicine in the treatment of chronic gastritis published in recent ten years. Methods Literatures related to the treatment of chronic gastritis with traditional Chinese medicine published on China National Knowledge Infrastructure from January 2011 to December 2020 were retrieved as the research objects. The author, institution and keywords of the literatures were extracted, and statistics and visualization were drawn by CiteSpace software. Results In the past ten years, there were 364 literatures on traditional Chinese medicine treatment of chronic gastritis; 855 authors and 1609 partnerships; there were 481 published institutions and 349 institutional partnerships. There was more collaboration among authors than among institutions. A total of 613 keywords were involved, including 29 keywords with frequency ≥five and seven mutated keywords. In recent ten years, the research focused mainly on Helicobacter pylori, clinical efficacy and safety evaluation, gastritis with deficient cold of spleen and stomach, application of traditional Chinese medicine characteristic therapy, chronic atrophic gastritis, use of Huangqi Jianzhong Decoction and other classical prescriptions, and so on. Conclusion In the past ten years, there have been many research hotspots and extensive coverage on traditional Chinese medicine treatment of chronic gastritis, but the cooperation between research institutions is not strong, there are academic barriers, scientific research output is little, and clinical research evidence needs to be further strengthened. Helicobacter pylori, clinical research and safety evaluation, gastritis with deficient cold of spleen and stomach, acupoint application of traditional Chinese medicine will continue to be the focus of future research. It is suggested to strengthen institutional cooperation, improve the evidence quality of traditional Chinese medicine treatment of chronic gastritis, and increase the output of results.
		2022 Vol. 19 (18): 98-101 [Abstract] ( 63 ) HTML (1 KB) PDF (2150 KB) ( 28 )

	102	Analysis of the drug rule of Feng Jianhua in the treatment of diabetes mellitus type 2 based on data mining
		NI Linlin1 XU Yunsheng2 ZHOU Honglei3
		[Abstract] Objective To analyze the drug rule and characteristics of Professor Feng Jianhua in the treatment of diabetes mellitus type 2, and to provide reference for the treatment of diabetes mellitus with traditional Chinese medicine. Methods The outpatient traditional Chinese medicine prescription data of Professor Feng Jianhua in the Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine for the treatment of diabetes mellitus type 2 patients from January 2000 to December 2020 were collected from the database of Famous Doctor Inheritance System jointly developed by Beijing University of Chinese Medicine and Institute of Computing Technology, Chinese Academy of Sciences. Through data analysis, drug use frequency, drug taste and channel frequency were counted, common drug pairs were found through association analysis, and core prescriptions were extracted by constructing drug relationship network graph. Results A total of 120 patients with diabetes mellitus type 2 were included in this study, and 96 Chinese medicines were used in total. The top five ingredients of drug frequency were unprocessed Rehmanniae Radix, Coptidis Rhizoma, Anemarrhenae Rhizoma, corn stigma, and Salviae Miltiorrhizae Radix Et Rhizoma. The top five drug tastes were sweet, bitter, pungent, sour, and tasteless. The top five channel tropism frequencies were liver, lung, kidney, stomach, and spleen channels. The most common drug was unprocessed Gypsum Fibrosum-Anemarrhenae Rhizoma. The core prescription was unprocessed Rehmanniae Radix, Salviae Miltiorrhizae Radix Et Rhizoma, corn stigma, Coptidis Rhizoma, Anemarrhenae Rhizoma, Schisandrae Chinensis Fructus, unprocessed Gypsum Fibrosum, Puerariae Lobatae Radix. Conclusion Professor Feng is good at using replenishing the vital essence and removing heat drugs in the treatment of diabetes mellitus. The drug tastes are mostly sweet and bitter, Gypsum Fibrosum-Anemarrhenae Rhizoma are most often used together.
		2022 Vol. 19 (18): 102-105,118 [Abstract] ( 96 ) HTML (1 KB) PDF (1321 KB) ( 23 )

	106	Clinical effect of floating needle therapy in the treatment of somatoform pain disorders in the elderly
		ZHAI Xiangnan1 WANG Li1 WANG Xiaohuan1 MA Zhanping2▲
		Objective To study the clinical effect of floating needle therapy in the treatment of somatoform pain disorders in the elderly. Methods A total of 100 elderly patients with somatoform pain disorders admitted to the Seventh People’s Hospital of Hengshui City, Hebei Province from January to December 2020 were selected as the research objects. According to the random number table method, they were divided into the observation group and the control group, with 50 cases in each group. The control group was treated with Duloxetine and conventional acupuncture therapy, and the observation group was treated with Duloxetine and floating needle therapy. After 8 weeks of continuous treatment, the short-form McGill pain questionnaire (SF-MPQ) score, serum cortisol level, sleep quality (Pittsburgh sleep quality index [PSQI]) and quality of life were compared between the two groups before and after treatment. Results After treatment, the SF-MPQ scores in both groups were lower than those before treatment (P ＜ 0.05), and that in the observation group was lower than that in the control group (P ＜ 0.05). After treatment, the serum cortisol level of the observation group was lower than that before treatment, and that in the observation group was lower than that in the control group (P ＜ 0.05). After treatment, PSQI scores in both groups were lower than those before treatment, and that in the observation group was lower than that in the control group (P ＜ 0.05). After treatment, the scores of physiological function, psychological function, social relationship, and surrounding environment in both groups were higher than those before treatment, and those in the observation group were higher than those in the control group (P ＜ 0.05). Conclusion Floating needle therapy combined with Duloxetine in the treatment of elderly patients with somatoform pain disorders can relieve pain, reduce serum cortisol level, and improve the quality of sleep and the quality of life of patients. It is worthy of clinical application.
		2022 Vol. 19 (18): 106-109 [Abstract] ( 68 ) HTML (1 KB) PDF (550 KB) ( 25 )

	110	Analysis of feeling the pulse’s method and clinical significance of slippery-hesitant pulse
		YANG Xiuting1 ZHANG Ziyi2 GAO Cai3 ZHANG Haiying1 WANG Qiuju1
		The slippery pulse and the hesitant pulse are common pulse in clinic. It is generally believed that it is difficult to coexist with both. In clinical practice, it has been found that both can occur simultaneously in pathological conditions, especially in the later stage of damp-heat pathogenic. This paper discusses the form and clinical significance of the slippery-hesitant pulse from the perspective of basic theory and clinical practice of pulse science. The correct understanding and grasp of slippery-hesitant pulse has important clinical practical significance for judging the nature, stage, severity of disease, and formulating treatment principles.
		2022 Vol. 19 (18): 110-113 [Abstract] ( 65 ) HTML (1 KB) PDF (652 KB) ( 31 )

	114	Professor Gao Zhan’s experience in the treatment of urinary incontinence after radical prostatectomy
		WANG Zhong1 WANG Jianwen2 SHAO Kuiqing1 LI Qi1 DING Jiasen1 CHEN Haote1 GAO Zhan1
		This paper summarizes Professor Gao Zhan’s experience in the treatment of urinary incontinence after radical prostatectomy. Professor Gao Zhan believes that the basis of this disease are weakness of the elderly and tumor consumption, and the pathogenic conditions of this disease are surgical injury, heat and blood stasis during operation. Professor Gao Zhan points out that the pathogenesis is spleen and kidney deficiency, and stasis and heat binding, both of them lead to bladder failing to control. The disease location is bladder, and the deficient syndrome is the most common type, with intermingled deficiency and excess. In the treatment, we should give consideration to manifestation and root cause and treating with both elimination and reinforcement. Treatment based on syndrome differentiation combined with staging treatment is necessary. The treatment is mainly to replenish qi and fortify spleen, supplemented by tonifying kidney to reinforce and arrest with astringent therapy, accompanied by clearing heat and removing blood stasis. Professor Gao Zhan takes the self-designed Qishao Tianxin Prescription as the basic prescription, flexibly adds and subtracts Chinese herbs according to the clinical actual situation of patients, and achieves remarkable effect after application in clinical practice. One medical record is attached to prove our view.
		2022 Vol. 19 (18): 114-118 [Abstract] ( 59 ) HTML (1 KB) PDF (784 KB) ( 61 )

	119	Clinical effect of external application of Chanxiong Plaster on gastric cancer pain with syndrome of blood stasis and heat toxin
		XU Zhangying1 HUANG Lingying2 GAO Yueqiu2 XUE Yuzheng3▲
		[Abstract] Objective To observe the effect of external application of Chanxiong Plaster on gastric cancer pain with syndrome of blood stasis and heat toxin. Methods A total of 72 patients with gastric cancer pain with syndrome of blood stasis and heat toxin treated in Xishan Traditional Chinese Medicine Hospital of Wuxi, Jiangsu Province from January 2019 to July 2021 were selected as the research subjects, according to random number table method, they were divided into observation group and control group, with 36 cases in each group. The control group was treated with three-step standard treatment, and the observation group was treated with external application of Chanxiong Plaster. After one week, the clinical efficacy, pain relief onset time, pain relief duration time, burst pain times, traditional Chinese medicine syndrome score were compared. Serum 5-hydroxytryptamine (5-HT) and β-endorphin (β-EP) levels were detected before and after treatment, and the safety was evaluated. Results In the observation group, 34 cases were observed and two cases were fell off. In the control group, 33 cases were observed and three cases were fell off. The clinical efficacy of the observation group was better than that of the control group, the difference was statistically significant (P ＜ 0.05). After treatment, the onset time of pain relief and the outbreak times of pain in the observation group were shorter than those in the control group (P ＜ 0.05); the duration time of pain relief in the observation group was longer than that in the control group, the difference was statistically significant (P ＜ 0.05). After treatment, and the scores of traditional Chinese medicine syndrome in the observation group were lower than those in the control group, the differences were statistically significant (P ＜ 0.05). After treatment, the serum 5-HT contents in both groups were lower than those before treatment, and that in the observation group was lower than that in the control group, while the β-EP contents in both groups were increased, and that in the observation group was higher than that in the control group, the difference was statistically significant (P ＜ 0.05). In this study, two patients in observation group showed symptoms of pruritus and mild edema at the application site after treatment, which disappeared after external application of Qingdai Powder. No obvious adverse events were observed in control group. Conclusion External application of Chanxiong Plaster can effectively treat gastric cancer pain with syndrome of blood stasis and heat toxin without obvious adverse reactions, and it is worthy of clinical promotion.
		2022 Vol. 19 (18): 119-122,127 [Abstract] ( 60 ) HTML (1 KB) PDF (748 KB) ( 25 )

	123	Effects of acupotomy on activity, apoptosis, and autophagy of primary chondrocytes in knee osteoarthritis rabbits
		XIU Zhongbiao1 LIU Hong1 ZHANG Liangzhi1 LIU Jing1 LIN Qiaoxuan2 LU Liming3 GUO Zexing3 YANG Jinsuo3
		Objective To observe the effects of acupotomy on chondrocyte activity, apoptosis, and autophagy in rabbits with knee osteoarthritis (KOA). Methods Twenty-four healthy six-month-old male New Zealand rabbits with body weight of (2.5±0.5) kg were divided into blank group, model group, and acupotomy group by random number table method, with eight rabbits in each group. Model group and acupotomy group were used to prepare KOA rabbit model by modified Videman method, and fixed for six weeks. Blank group was not processed. The model was evaluated by X-ray examination. In acupotomy group, common tendons were selected for acupotomy release, once a week, a total of four times. The blank and model groups were not processed. One week after the intervention, primary chondrocytes were extracted from the cartilage surface of the femoral medial and lateral condyles of the rabbit left knee joint, and the cell activity was detected by CCK-8. Apoptosis rate was detected by Annexin V-FITC/PI double staining flow cytometry. LC3B immunofluorescence staining was used to detect autophagy. Results The comparison of cell activity at each time point in three groups were statistically significant (P ＜ 0.05). The cell viability in the model group was lower than that in the blank group, and the cell viability in the acupotomy group was higher than that in the model group at the same time (P ＜ 0.05). The chondrocyte apoptosis rate in the model group was higher than that in the blank group (P ＜ 0.05), and the chondrocyte apoptosis rate in the acupotomy group was lower than that in the model group (P ＜ 0.05). Compared with the blank group, the fluorescence intensity of LC3B in the model group decreased; compared with the model group, the fluorescence intensity of LC3B in the needle knife group was enhanced. Conclusion Based on the balance theory of muscles and bones through the tendon system, acupotomy can enhance the autophagy level of primary chondrocytes in KOA rabbits, improve cell activity and reduce cell apoptosis.
		2022 Vol. 19 (18): 123-127 [Abstract] ( 99 ) HTML (1 KB) PDF (1602 KB) ( 68 )

	128	Clinical effect of acupotomy treating knee osteoarthritis base on the theory of infrapatcllar fat
		YE Xixi1 FAN Pei1 LU Di1 ZHOU Yi1 LI Kaiping2
		Objective To dicuss the clinical effect of acupotomy treating knee osteoarthritis base on the theory of infrapatcllar fat. Methods A total of 70 knee osteoarthritis patients who were treated in the Second Affiliate Hospital of Wenzhou Medical University from April 2020 to April 2021, and they were divided into experimental group and control group by random number table method, with 35 cases in each group. The experimental group treated with fan-shaped release infrapatcllar fat and traditional operate release，the control group treated with traditional operate release, treatment once a week, a total of four treatments. The visual analog scale (VAS) and Lysholm score were evaluated before treatment, one week after treatment, and three months after treatment, and the curative effect was evaluated. Results One weeks and three months after treatment，VAS scores in two groups were lower than those before treatment, and those in the experimental group were lower than the control group, Lysholm scores in two groups were higher than those before treatment, and those in the experimental group were higher than the control group, the differences were statistically significant (P ＜ 0.05). The curative effect of the experimental group was better than that of the control group, and the difference was statistically significant (P ＜ 0.05). Conclusion Fan-shaped release infrapatcllar fat pad and traditional operate release can relieve knee pain and mobility disorders more effectively, which is worthy of clinical promotion.
		2022 Vol. 19 (18): 128-131 [Abstract] ( 96 ) HTML (1 KB) PDF (601 KB) ( 42 )

	132	Analysis of the principle of 10-point-acupuncture on cervical vertebra treating cervical spondylosis under the guidance of holistic lysis with acupotome
		REN Haitao QI Fengjun ZHANG Tianmin
		This paper under the guidance of the idea of “T-shaped acupotomy for holistic release” and according to the understanding of the etiology and pathology of cervical spondylosis by acupotomy medicine and acupuncture and moxibustion, “10-point-acupuncture” for the treatment of cervical spondylosis by acupuncture and moxibustion are designed. This paper introduces in detail the method of acupoint selection and operation of acupuncture and moxibustion, and analyzes the principle of the treatment of cervical spondylosis by “10-point-acupuncture” from the perspectives of acupotomology and acupuncture, and expounds the rationality of the treatment of cervical spondylosis by “10-point-acupuncture”. It provides a new method for the treatment of cervical spondylosis.
		2022 Vol. 19 (18): 132-135 [Abstract] ( 60 ) HTML (1 KB) PDF (600 KB) ( 17 )

	136	Application effect of the Metabolic Management Center mode led by specialist nurses in self-management ability of patients with type 2 diabetes
		WANG Xiaojing ZHAO Wenying DONG Huan LI Aihua ZHANG Yuanyuan KE Jing ZHAO Dong▲
		Objective To explore the application effect of the Metabolic Management Center (MMC) mode led by specialist nurses on self-management ability for type 2 diabetic patients. Methods A total of 121 patients with type 2 diabetes who visited the Department of Endocrinology, Beijing Luhe Hospital, Capital Medical University from August to October 2021 were selected as subjects by convenience sampling method. According to the random number table method, they were randomly divided into intervention group with 61 cases and control group with 60 cases. The control group implemented a routine MMC management, and the intervention group implemented the MMC mode led by specialist nurses, the intervention lasted for three months. The changes of glycosylated hemoglobin (HbA1c), diabetes knowledge score, and diabetes self-management behavior score were compared between the two groups before and after intervention. Results After intervention, the levels of HbA1c in the two groups were lower than before intervention, and the intervention group was lower than the control group, the differences were statistically significant (P ＜ 0.05). Diabetes knowledge scores of the two groups were higher than before intervention, and the intervention group was higher than the control group, the differences were statistically significant (P ＜ 0.05). The scores of each dimension of self-management behavior in the two groups were better than before intervention, and the intervention group was better than the control group, the differences were statistically significant (P ＜ 0.05). Conclusion Compared with routine MMC management, the MMC mode led by specialist nurses can more effectively improve the level of the self-management behavior of patients with type 2 diabetes and contribute to blood glucose control, which is worthy of clinical promotion.
		2022 Vol. 19 (18): 136-140 [Abstract] ( 108 ) HTML (1 KB) PDF (667 KB) ( 91 )

	141	Clinical value of three-dimensional quality evaluation model in patients with diarrhea after kidney transplantation
		GAO Ranran HUANG Yuanyuan JIN Ping ZHANG Chengwei
		Objective To explore the effect of applying three-dimensional quality evaluation model in patients with diarrhea after kidney transplantation. Methods A total of 106 patients with diarrhea after kidney transplantation admitted to Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School from March 2018 to March 2020 were selected. The patients were divided into control group and observation group by random number table method, with 53 cases in each group. The control group received routine intervention, and the observation group received structure process structure three-dimensional quality evaluation model intervention. The incidence of perianal dermatitis, negative emotion, quality of life and satisfaction before and after intervention were compared between the two groups. Results After the intervention, the incidence of perianal dermatitis in the observation group was lower than that in the control group (P ＜ 0.05); the scores of Hamilton anxiety scale and Hamilton depression scale in both groups were lower than before intervention, and the scores of the observation group were lower than those of the control group after intervention (P ＜ 0.05); the scores of all dimensions of quality of life in the two groups were higher than before intervention, and the scores of all dimensions of quality of life in the observation group were higher than the control group (P ＜ 0.05), and the scores of satisfaction in the observation group were higher than those in the control group (P ＜ 0.05). Conclusion The application of three-dimensional quality evaluation model in patients with diarrhea after renal transplantation can reduce the incidence of perianal dermatitis, relieve negative emotions, and improve the satisfaction of patients with quality of life.
		2022 Vol. 19 (18): 141-144,165 [Abstract] ( 72 ) HTML (1 KB) PDF (713 KB) ( 39 )

	145	Nursing effect of surface, line, and point combined scraping therapy for insomnia with syndrome of liver depression thansforming in to fire
		YU Lijun DING Dingming LI Sikang
		Objective To observe and analyze the nursing effect of scraping therapy combined with the surface, line, and point for insomnia with syndrome of liver depression thansforming in to fire. Methods A total of 60 patients with insomnia with syndrome of liver depression thansforming in to fire were selected from January 2020 to June 2021 in the outpatient Department of Acupuncture and Moxibustion of Wuhu Hospital of Traditional Chinese Medicine in Anhui Province. The patients were divided into control group and experimental group by random number table method, with 30 cases in each group. The control group was given routine nursing intervention, the experimental group was given surface, line, and point combined with scraping therapy intervention on the basis of the control group, and 14-day course of treatment. Pittsburgh sleep quality index scale (PSQI), traditional Chinese medicine syndrome score, and international standard sleep efficiency index were compared between the two groups before and after treatment. Results After intervention, PSQI scores in traditional Chinese medicine syndrome both groups were lower than before, and the scores in experimental group were lower than control group (P ＜ 0.05). The traditional Chinese medicine syndrome scores of the two groups were lower than before intervention, and the traditional Chinese medicine syndrome score of the experimental group was lower than the control group (P ＜ 0.05). The clinical efficacy of experimental group was better than that of control group (P ＜ 0.05). Conclusion Surface, line, and point combined with scraping therapy can improve the sleep quality and clinical symptoms of patients with liver depression and fire insomnia.
		2022 Vol. 19 (18): 145-148 [Abstract] ( 62 ) HTML (1 KB) PDF (668 KB) ( 54 )

	149	Meta analysis of the effect of emotional intervention of psychological nursing on elderly patients with acute myocardial infarction
		GUO Yan LIU Ying▲ AN Lijun
		Objective To systematically evaluate the emotional intervention effect of psychological nursing on elderly patients with acute myocardial infarction. Methods The retrieval formula was compiled with the key words “acute myocardial infarction” and “psychological nursing”, and the academic papers in various Chinese and English medical databases such as VIP, the Cochrane Library, CNKI, Web of Science, CBM, PubMed and Wanfang Data were searched and screened. The retrieval time limit was from the inception to December 2021, the bias risk assessment and meta analysis of the included literature were carried out by RevMan 5.3 software of Cochrane company. Results A total of 11 randomized controlled trials were included. Meta-analysis showed that psychological nursing could significantly reduce the anxiety self-rating scale in elderly patients with acute myocardial infarction (MD = -5.95, 95%CI: -6.61 to -5.29, P ＜ 0.000 01) and depression self-rating scale (MD = -8.98, 95%CI:-9.77 to -8.19, P ＜ 0.000 01). Conclusion Psychological nursing can significantly improve the psychological states of elderly patients with acute myocardial infarction, such as anxiety and depression. At the same time, it can also improve the compliance and quality of life of patients, which is worthy of promotion in clinic.
		2022 Vol. 19 (18): 149-153 [Abstract] ( 101 ) HTML (1 KB) PDF (2137 KB) ( 68 )

	154	Application of mind map in emergency procedure of patients with acute cerebral hemorrhage
		LI Xuefang OUYANG Yan XU Wei HUANG Haidi▲
		Objective To explore the application effect of mind map in the emergency procedure of patients with acute cerebral hemorrhage. Methods A total of 41 patients with acute cerebral hemorrhage who underwent routine cerebral hemorrhage emergency procedures from February 2018 to March 2019 in Chenzhou First People’s Hospital were selected as the control group, while a total of 52 patients with acute cerebral hemorrhage who adopted the first aid procedure in the mind map mode from April 2019 to May 2021 in our hospital were selected as the observation group. The differences in rescue time (emergency time, triage assessment time, emergency stay time), neurological function, self-care ability, and negative mood scores (self-rating anxiety scale [SAS] score, self-rating depression scale [SDS] score) before and after intervention, and prognosis were compared between the two groups. Results The emergency time, triage evaluation time, and emergency stay in the observation group were shorter than those in the control group, and the differences were highly statistically significant (P ＜ 0.01). After the intervention, while National Institutes of Health Stroke Scale scores in the two groups were lower than those before the intervention, and the observation group was lower than the control group, and the differences were statistically significant (P ＜ 0.05); Barthel index was higher than that before intervention, while the observation group was higher than the control group, and the differences were statistically significant (P ＜ 0.05). After the intervention, the SAS and SDS scores of the two groups were lower than those before the intervention, while those of the observation group were lower than those of the control group, and the differences were statistically significant (P ＜ 0.05). The prognosis of the observation group was better than that of the control group, and the difference was statistically significant (P ＜ 0.05). Conclusion Using mind map mode to intervene in the emergency procedure of patients with acute cerebral hemorrhage can effectively shorten the rescue time, reduce the neurological damage of patients with cerebral hemorrhage, improve the quality of life, and improve the prognosis.
		2022 Vol. 19 (18): 154-157 [Abstract] ( 72 ) HTML (1 KB) PDF (736 KB) ( 32 )

	158	Effects of short-term structural psychoeducational intervention on pain, compliance, and resilience of microtia patients undergoing external ear reconstruction
		ZHAO Feifei ZHU Xingyan CAI Yanli▲
		Objective To explore the effect of short-term structured psychoeducational intervention on pain, compliance, and resilience of microtia patients undergoing external ear reconstruction. Methods A total of 120 patients with microtia treated in the First Affiliated Hospital of Air Force Military Medical University of the People’s Liberation Army from June 2020 to June 2021 were selected as the research objects. According to the random number table method, they were divided into observation group and control group, with 60 cases in each group. The perioperative control group received routine nursing intervention; the observation group used short-term structured psychological education intervention. The degree of pain at different time points was compared between the two groups; the pain degree of the two groups at different postoperative points was compared. The psychological situation and compliance of the two groups were compared before and after intervention. Results Visual analog scale (VAS) scores at 2, 24, and 36 h after surgery were compared between intra-subject effect and inter-subject effect, the differences were statistically significant (P ＜ 0.05); comparison of postoperative VAS scores between the two groups, the difference was statistically significant (P ＜ 0.05); the VAS scores of the observation group were lower than those of the control group at 2, 24, and 36 h after surgery, and the differences were statistically significant (P ＜ 0.05), the psychological resilience scale (CD-RISC) scores of the two groups were higher than before the intervention, the self-rating anxiety scale (SAS) and self-rating depression scale (SDS) scores were lower than before the intervention; CD-RISC score of observation group was higher than control group, SAS and SDS scores were lower than control group, the differences were statistically significant (P ＜ 0.05); the compliance of observation group was better than control group, and the difference was statistically significant (P ＜ 0.05). Conclusion Short-term structured psychological education intervention can significantly alleviate the postoperative pain of patients with microtia and improve their psychological elasticity and compliance.
		2022 Vol. 19 (18): 158-160,169 [Abstract] ( 73 ) HTML (1 KB) PDF (714 KB) ( 35 )

	162	Application effect of psychological intervention based on the hierarchy of needs theory in patients with viral encephalitis and mental symptoms
		ZHOU Haiying1 WU Yunying2 HE Qin1
		Objective To explore the application effect of psychological intervention based on the hierarchy of needs theory in patients with viral encephalitis (VE) and mental symptoms. Methods A total of 120 patients with VE and mental symptoms treated in The First Affiliated Hospital of Chengdu Medical College were enrolled between June 2018 and June 2020. According to random number table method, they were divided into observation group and control group, with 60 cases in each group. The control group received routine nursing, and the observation group received psychological intervention based on hierarchy of needs theory. The improvement of mental symptoms and incidence of unsafe events were compared between the two groups after intervention, and the changes of bad mood and motor spasm were compared between the two groups before and after intervention. Results After intervention, the total effective rate of observation group was higher than control group, the total incidence of unsafe events was lower than control group, the differences were statistically significant (P ＜ 0.05); the scores of self-rating anxiety scale and self-rating depression scale in both groups were lower than before intervention, and those of the observation group were lower than control group, the differences were statistically significant (P ＜ 0.05); the motor spasms in both groups were better than before intervention, and the improvement of observation group was better than control group, the difference was statistically significant (P ＜ 0.05). Conclusion Psychological intervention based on the hierarchy of needs theory can significantly improve mental state of patients with VE and mental symptoms, reduce the occurrence of risk events, improve negative emotions and promote the recovery of limbs function.
		2022 Vol. 19 (18): 162-165 [Abstract] ( 65 ) HTML (1 KB) PDF (574 KB) ( 21 )

	166	Preventive effects of nursing intervention of lower limbs deep vein thrombosis in women after cesarean section based on risk line graph model
		LI Ronghui LAI Yahui HUANG Haiyan
		Objective To explore the preventive effects of nursing intervention based on risk line graph model on lower limbs deep vein thrombosis of women in cesarean section. Methods A total of 200 pregnant women with cesarean section admitted to the Department of Obstetrics of Suining Central Hospital from January 2019 to January 2021 were selected as the research object. They were divided into control group and observation group by random number table method, with 100 cases in each group. The control group received routine nursing, and the observation group received nursing intervention based on risk rosette model, the nursing satisfaction and deep venous thrombosis of lower limbs were compared between the two groups. Results The incidence of lower limbs deep vein thrombosis in observation group was lower than that in control group (P ＜ 0.05). Nursing satisfaction of observation group was higher than control group (P ＜ 0.05). Conclusion Nursing intervention based on risk line graph model can reduce lower limbs deep vein thrombosis in cesarean delivery women, which is recognized by women, and worthy of widespread clinical promotion and application.
		2022 Vol. 19 (18): 166-169 [Abstract] ( 108 ) HTML (1 KB) PDF (850 KB) ( 56 )

	170	One case report of osteofibrous dysplasia with aneurysmal bone cyst
		ZHENG Xiaohui1 YUAN Puwei2 LI Xiaoqun3 ZHU Fengfeng3 TUO Zhenhe3 WANG Zhankui3
		Osteofibrous dysplasia is a benign neoplastic lesion characterized by bone fibrodegeneration. Aneurysmal bone cysts get their name because of localized lesions and periperiosteal reactive bone deposits similar to aneurysmal distension, but the combination of the two is rare. Due to its low incidence, it is easy to be misdiagnosed. At present, pathological examination is the main means of diagnosis, imaging examination can provide a higher diagnosis basis before diagnosis, and surgery is the main treatment. Author collected one patient diagnosed with osteofibrous dysplasia with aneurysmal bone cyst and treated with femoral lesion curettage and iliac bone grafting in the Affiliated Hospital of Shaanxi University of Chinese Medicine in September 2021, and discussed the imaging, pathology, clinical diagnosis, and treatment of this rare disease by reviewing relevant literature.
		2022 Vol. 19 (18): 170-172,184 [Abstract] ( 74 ) HTML (1 KB) PDF (1025 KB) ( 38 )

	173	Research on organizational performance improvement path of primary healthcare institutions in Beijing based on system dynamics
		CUI Chengsen1* ZHUANG Nan2* MENG Kai1▲
		Objective To built primary healthcare institutions system dynamics model, in order to provide scientific basis for improving the organizational performance of primary healthcare institutions in China. Methods The Vensim software was used to build primary healthcare institutions system dynamics model, and the years from 2016 to 2019 were taken as the historical years, and the years from 2020 to 2030 were taken as the future years for simulation. Data were derived from institutional reports and health statistics yearbooks. Results When the ability of organization, government financial aid in primary healthcare institutions, and grassroots medical staff wage income increased, number of patients treated by primary healthcare institutions, first diagnosis rate at primary level, number of people hospital diagnosis and treatment, number of people hospital turn number, annual income of primary doctors, and per capital number of primary level doctors and other performance indicators were in different degrees of improvement. At the same time, when a variety of policies were adjusted together, the improvement of organizational performance was more obvious. Conclusion This study further verified the policy path of improving the organizational performance of primary healthcare institutions through the policy experiment of the model. Primary healthcare institutions should strengthen the organizational capability, and the government should give full play to the responsibility of running healthcare institutions, strengthen the financial input of primary healthcare institutions, guarantee the salary of their staff, and formulate a reasonable performance management distribution system, so as to further improve the performance of primary healthcare institutions.
		2022 Vol. 19 (18): 173-179,189 [Abstract] ( 69 ) HTML (1 KB) PDF (4245 KB) ( 25 )

	180	Experience and enlightenment of World Health Organization’s initiatives to promote innovation and accessibility of global health governance
		MA Lin ZHENG Ying
		The policy for Framework of Engagement with Non-State Actors is an important content of World Health Organization reform and promotion of global health governance. World Health Organization Collaborating Centers is an important driving force for the implementation of this policy. This paper briefly reviews the policy development process of Framework for Engagement with Non-State Actors, based on the policy implementation angle induced by the World Health Organization Collaborating Centre in promoting global health governance practices, summarizes the experience and enlightenment the World Health Organization Collaborating Centre in promoting global health governance innovation mechanism, providing reference for the development of World Health Organization Collaborating Centers in China.
		2022 Vol. 19 (18): 180-184 [Abstract] ( 72 ) HTML (1 KB) PDF (959 KB) ( 62 )

	185	Problems and countermeasures of ethical review of scientific research projects in our hospital
		PAN Junhua ZHANG Di MI Fengling
		As an important means of standardizing research behavior and controlling research risk, ethical review has encountered some problems and challenges in the face of the increase of clinical research and fine management of hospital scientific research projects. This paper makes an in-depth analysis on the influencing factors and causes of ethical knowledge awareness, review mode selection, sample bank ethics, and follow-up review in the ethical review of scientific research projects in Beijing Chest Hospital, Capital Medical University, and puts forward to strengthen member access, evaluation and training, rich ethical review form, and strengthen coordination with academic review, standardize the process of informed signature of sample database, and promote the the ethical tracking and review and other corresponding solutions. This paper holds that accurately grasping the balance between the implementation of scientific research projects and following ethics to ensure the healthy and standardized development of clinical scientific research has strong applicable value for improving the ethical review quality of clinical research of hospital scientific research projects and perfecting the ethical review system. In the future, it will be our next focus to formulate ethical review norms for clinical scientific research topics based on the relevant international, domestic and hospital standards and actual conditions, and provide reference for other hospitals to carry out ethical review of scientific research topics.
		2022 Vol. 19 (18): 185-189 [Abstract] ( 69 ) HTML (1 KB) PDF (727 KB) ( 60 )

	190	Analysis of emergency management policy for public health emergencies in China
		YANG Zi HUANG Youliang WANG Hongyun Ranna·Ahati HE Nan ZHANG Xinyu LI Ruifeng
		Objective To provide reference for the main body of emergency management, the relevant policies of public health emergency management in China were summarized and the characteristics of policy-oriented development and change were analyzed. Methods From January 2003 to March 2021, 19 policy documents published on the official websites of the State Council, the State Emergency Management Department, the State Health Commission, the State Administration of Traditional Chinese Medicine, and other official websites were screened. The word frequency of the policy texts was counted and the time sequence analysis and content analysis were conducted. From the basic concept of management subject responsibility embodiment of service provision and development planning five dimensions to explore the status quo of policy development. Results Polices focued on “health” and “emergency”, the ranking of “prevention”, “health”, “construction”, and “strengthening” rised, while the ranking of “establishment” falls. The content of policies expands the prevention and control methods and participating industries, and refines the management objects. Conclusion The policies are characterized by compulsory, clear and strong targeting. It has gradually developed from “control-based” to “prevention and control combined” and presents a trend of multi-industry support and multi-subject development.
		2022 Vol. 19 (18): 190-193 [Abstract] ( 74 ) HTML (1 KB) PDF (949 KB) ( 168 )

	194	Convergence media construction and communication strategy of medical science and technology journals
		WANG Xia1 ZHAN Hongchun2
		As a kind of new media form, the convergence media has realized the innovation of communication carrier, medical science and technology journals should conform to the development trend of the times and step into a new stage of integration development. In the era of convergence media, medical science and technology journals need to be reformed in the aspects of information bearing content and form, purpose and form of information dissemination. Based on the current situation of the construction and dissemination of medical and health science and technology journals, this paper proposes the construction and dissemination strategies of medical and health science and technology journals: strengthening the top-level design of journals integrating media, and developing towards digital intensive development; innovating the operation mode of medical and health science and technology journals, and realizing the value of traffic. maximize; provide precise services to meet the individual needs of customers; use multimedia means to expand digital communication channels; strengthen the construction of media-integrated talents and improve the overall quality of the publication team.
		2022 Vol. 19 (18): 194-封三 [Abstract] ( 65 ) HTML (1 KB) PDF (622 KB) ( 184 )

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