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| Study on the correlation between osteoporosis and carotid atherosclerosis in elderly men with diabetes mellitus |
| SHI Li1 REN Weidong1 WANG Likun2 LI Chaoxi2 ZHANG Zhiying1 DENG Wenjuan1 HU Limei1 ZUO Lijuan1#br# |
1.Department of Endocrinology, the First Affiliated Hospital of Hebei North University, Hebei Province, Zhangjiakou 075000, China;
2.Department of Ultrasound Medicine, the First Affiliated Hospital of Hebei North University, Hebei Province, Zhangjiakou 075000, China |
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Abstract Objective To investigate the relationship between osteoporosis and carotid atherosclerosis in elderly male diabete mellitus patients in Zhangjiakou region, and to provide more scientific basis for the prevention and treatment of osteoporosis and arteriosclerosis. Methods A total of 100 elderly male patients with type 2 diabetes mellitus who were treated in the Department of Neurology, the First Affiliated Hospital of Hebei North University from September 2017 to September 2019 were selected. The age, body mass index, course of diabetes, hypertension, smoking, alcohol consumption, insulin application history, and related information were collected. The femoral neck bone mineral density and carotid intima-media thickness (IMT) were measured, and 100 patients were divided into carotid atherosclerosis group (66 cases) and non-atherosclerosis group (34 cases) according to relevant standards. The differences in clinical characteristics of the two groups were compared, and the correlation between bone mineral density and IMT was analyzed. Results There were significant differences in age, total cholesterol, triglyceride, low-density lipoprotein cholesterol, fasting blood glucose, glycosylated hemoglobin levels, and bone mineral density of femoral neck between the two groups, and the differences were statistically significant (P ＜ 0.05). The incidence of osteoporosis in the carotid atherosclerosis group was higher than that in the non-atherosclerosis group, and the difference was statistically significant (P < 0.05). Bone mineral density values were negatively correlated with carotid IMT values (r = -0.605, P < 0.05). Conclusion Aging, hyperglycemia, hyperlipidemia and other factors can affect carotid atherosclerosis in elderly male diabetes mellitus patients, and there is a significant correlation between osteoporosis and carotid atherosclerosis. Therefore, while preventing carotid atherosclerosis, it is necessary to pay close attention to the occurrence of osteoporosis, so as to reduce the risk of fracture.
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