妊娠期妇女甲状腺功能与血脂水平相关性研究

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Abstract Objective To investigate the correlation between thyroid function and blood lipid in pregnant women. Methods From April 2015 to April 2016, 250 cases of pregnant women were admitted to the Yancheng City No.1 People′s Hospital were selected, and they were divided into subclinical thyroid function hyperfunction group, hyperthyroidism group and normal group, subclinical hypothyroidism group, hypothyroidism group, 50 cases per group. Radioimmunoassay was used to detect the serum free triiodide (FT3) and free thyroxine (FT4) levels. Immunofluorescence analysis was used to detect the levels of thyrotropin (TSH) in serum. Determination of blood TC and TG levels in each group was taken by enzyme colorimetry. Determination of HDL-C and LDL-C levels was taken by immunosuppressive. The correlation analysis was conducted with FT3, FT4, TSH level and TC, TG, HDL-C level in blood. Results There was a statistical difference in FT3, FT4, TSH and serum lipid between every group (P < 0.05). The TSH level has positively correlated with TC, TG, LDL-C level (P < 0.05), and has no significant correlation with HDL-C (P > 0.05). The FT3 and FT4 levels had significantly negatively correlated with TC, TG and LDL-C levels (P < 0.05), and had no significant correlation with HDL-C level (P > 0.05). Conclusion Thyroid hormone levels in pregnancy are closely related to blood lipids. Hyperthyroidism in pregnancy can lead to levels of TG, TG, and LDL-C decreased.

Key words： Pregnancy Blood lipids Thyroid-stimulating hormone Free thyroid hormones Free triiodothyronine

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	XU Ke BIAN Dezhi WANG Chunlei HUANG Fei LIU Yamei▲

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XU Ke BIAN Dezhi WANG Chunlei HUANG Fei LIU Yamei▲. Correlation analysis between thyroid function and blood lipid in pregnant women[J]. 中国医药导报, 2018, 15(11): 91-94.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2018/V15/I11/91

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