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| Research progress of traditional Chinese medicine in regulating the autophagy of cardiovascular diseases |
| XU Jiwen1 LI Jinxia2 ZHANG Huamin3▲ |
1.Graduate School, Heilongjiang University of Chinese Medicine, Heilongjiang Province, Harbin 150040, China;
2.Institute of Basic Theory of TCM, China Academy of Chinese Medical Sciences, Beijing 100700, China;
3.Institute of Information on TCM, China Academy of Chinese Medical Sciences, Beijing 100700, China |
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Abstract Autophagy is a highly conservative process in which eukaryotic cells maintain homeostasis and it plays an regulatory role in the occurrence and development of cardiovascular disease (CVD) such as myocardial ischemia and reperfusion injury and atherosclerosis, which is a new target for CVD. The theory of traditional Chinese medicine, such as reestablishment to yin-yang equilibrium, phlegm stasis due to deficiency of qi, liver controlling conveyance and dispersion are closely related to autophagy. Many literatures show that the protective effect of TCM on cardiovascular disease is achieved through autophagy. In this paper, the autophagy in CVD is discussed, and a brief overview of the research progress in the regulation of CVD autophagy in Chinese medicine is presented.
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