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| The related research progress of epidermal growth factor receptor - extracellular signal regulated kinase signaling pathway in the ischemic cerebrovascular disease |
| ZHANG Qin AO Ting XIAO Shuying XU Na ZHANG Ruihua▲ |
| Department of Geriatric Medicine, Luhe Hospital, Capital Medical University, Beijing 101149, China |
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Abstract Ischemic cerebrovascular disease (ICD) is a common chronic disabling disease. This disease seriously affects the quality of lives of patients. The research shows that the epidermal growth factor receptor-extracellular signal regulated kinase (EGFR-ERK) pathway plays an important role on the pathophysiology process in ICD. However, the mechanism is still unclear. This article reviews the progress of the EGFR-ERK pathway in ICD, which provides references for further basic research and clinical treatment of ICD.
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