脑卒中相关性肺炎多重耐药性感染危险因素及控制措施

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Abstract Objective To understand the risk factors associated with multiple drug-resistant infections in stroke-associated pneumonia and to take relevant control measures based on the relevant risks. Methods A total of 540 acute stroke patients hospitalized from August 2013 to September 2014 in Hunan Normal University Affiliated Xiangnan Hospital were selected. Morning sputum was collected from patients with stroke-associated pneumonia for multi-drug resistance. Univariate and multivariate logistic analyzes were used to analyze the risk factors that led to hospital-acquired nosocomial infections. Results Among the 540 patients with acute stroke, 89 cases were associated with pneu monia and the infection rate was 16.46%. A total of 167 pathogenic bacteria were isolated from 89 stroke-associated pneumonia (SAP) patients, of which 123 were multi-drug resistant bacteria, and the gram-negative bacteria accounting for 68.29% with pseudomonas aeruginosa, klebsiella pneumoniae and acinetobacter baumannii. Gram-positive bacteria accounting for 31.71% with staphylococcus haemolyticus and staphylococcus aureus. The results showed that patients aged≥ 50 years, hospital stay≥ 30 d, with diabetes, disturbance of consciousness, hypoproteinemia, mechanical ventilation and indwelling nasogastric tube and other related invasive procedures were independent risk factors for SAP multidrug resistance (P ＜ 0.05). Conclusion SAP incidence is clinically relatively high, and the incidence of pneumonia associated with the distribution of pathogens are mainly multi-resistant bacteria. Therefore, it is of great significance to use targeted preventive measures to understand the distribution of pathogenic bacteria and the risk factors that cause the multiple drug resistance of SAP.

Key words： Stroke Related pneumonia Multiple drug resistance Risk factors

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	LUO Ya1
	2 LI Zhongqiu1 ZENG Meifang2

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LUO Ya1,2 LI Zhongqiu1 ZENG Meifang2. Risk factors and control measures of multidrug resistance in stroke - related pneumonia[J]. 中国医药导报, 2018, 15(8): 108-111,133.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2018/V15/I8/108

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