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| Comparison of the clinical effects of intravascular interventional therapy and simple drug therapy on ischemic cerebrovascular disease |
| Zuhereayi·yahefu1 DANG Hui1 WANG Chengfeng1 CHEN Wei2 |
1.Department of Neurology, the People′s Hospital of Xinjiang Autonomous Region, Xinjiang Uygur Autonomous Region, Urumqi 830000, China;
2.Department of Neurosurgery, the First Affiliated Hospital of Xi′an Jiao Tong University, Shaanxi Province, Xi′an 710061, China |
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Abstract Objective To explore the clinical effect of endovascular treatment and simple drug treatment in the patients with ischemic cerebrovascular disease. Methods One hundred and twenty patients with ICVD in the People′s Hospital of Xinjiang Autonomous Region from January 2013 to January 2016 were randomly drawn, and they were randomly divided into the observation group and the control group, 60 cases in each group. The patients in the observation group were treated with endovascular treatment on the basis of drug treatment, and the control group was only treated with single drugs treatment. One year later, patients of two groups were followed up. The hemodynamic improvement, NIHSS, degree of vascular stenosis and the incidence of adverse reactions were evaluated in two groups, respectively. Results After treatment for one year, the effect of the part of the vertebral artery, basilar artery, internal carotid artery and carotid artery peak systolic velocity in the observation group were better than that in the control group, the differences were statistically significant (P < 0.01). The NIHSS of the observation group was lower than that in the control group, the difference was statistically significant (P < 0.01). The degree of vascular stenosis after treatment was significantly lower than the control group, the difference was statistically significant (P < 0.01). The incidence of adverse reaction in the observation group was also lower than that of the control group, the difference was statistically significant(P < 0.05). Conclusion Endovascular treatment is superior to simple drug therapy in terms of the hemodynamic improvement, NIHSS, vascular stenosis degree and incidence of adverse reactions in the treatment of ICVD, it is worthy of clinical promotion.
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