|
|
|
| Effects of PM2.5 on respiratory system and the development of probiotics in respiratory tract |
| ZHANG Yu XIAO Chunling |
| Department of Environmental Pollution and Health, Shenyang Medical College, Liaoning Province, Shenyang 110034, China |
|
|
|
Abstract When the atmosphere is polluted, the content of various suspended particulates in the atmosphere will increase, especially the fine particulate matter PM2.5. Due to its small particle size and large specific surface area, PM2.5 is easy to adsorb toxic and harmful substances in the air and stays in the air for a long time and has a long transportation distance. Therefore, it occupies an important position in air pollution. PM2.5 easily avoids nasal and bronchial cilia filtration, nasal invasion to the alveoli and deposited in the lung tissue, causing upper respiratory tract infection, and bronchial asthma, pneumonia and other symptoms. Respiratory infections not only affect the healthy development, but also cause a lot of complications, but also serious life-threatening. Classification of respiratory flora, the advantages of bacteria made of probiotics to regulate respiratory microecosystem disorders and other probiotics probiotics research are developing. In recent years, intestinal, vaginal probiotics on human diseases such as microbiological treatment has reached a certain effect, but less application of respiratory probiotics, the finished product treatment needs further research and development.
|
|
|
|
|
|
[1] Sun W，Sun J. Daily PM2.5 concentration prediction based on principal component analysis and LSSVM optimized by cuckoo search algorithm [J]. J Environ Manage，2017，188：144-152.
[2] Omidvarborna H，Kumar A，Kim DS. Variation of diesel soot characteristics by different types and blends of biodiesel in a laboratory combustion chamber [J]. Sci Total Environ，2016，544：450-459.
[3] Baxter LK，Duvall RM，Sacks J. Examining the effects of air pollution composition on within region differences in PM2.5 mortality risk estimates [J]. J Expo Sci Environ Epidemiol，2013，23（5）：457-465.
[4] Donaldson K，Stone V，Clouter A，et al. Ultrafine particles [J]. Occup Environ Med，2001，58（3）：211-216，199.
[5] Lipfert FW. Long-term associations of morbidity with air pollution：a catalog and synthesis [J]. J Air Waste Manag Assoc，2017.DOI：10.1080/10962247.2017.1349010.
[6] 乔玉霜，王静，王建英.城市大气可吸入颗粒物的研究进展[J].中国环境监测，2011，27（2）：22-26.
[7] Kong S，Lu B，Ji Y，et al. Risk assessment of heavy metals in road and soil dusts within PM2.5，PM10 and PM100 fractions in Dongying City，Shandong Province，China [J]. J Environ Monit，2012，14（3）：791-803.
[8] Potera C. Toxicity beyond the lung：connecting PM2.5，inflammation，and diab tes [J]. Environ Health Perspect，2014， 122（1）：A29.
[9] Jo EJ，Lee WS，Jo HY，et al. Effects of particulate matter on respiratory disease and the impact of meteorological factors in Busan，Korea [J]. Respir Med，2017，124：79-87.
[10] Ferreira TM，Forti MC，de Freitas CU，et al. Effects of particulate matter and its chemical constituents on elderly hospital admissions due to circulatory and respiratory diseases [J]. Int J Environ Res Public Health，2016，13（10）：497.
[11] 崔硕.基于微流控芯片技术的PM2.5对支气管上皮细胞16HBE上皮间质转化影响的研究[D].大连：大连医科大学，2015.
[12] Zhang T，Gao B，Zhou Z，et al. The movement and deposition of PM2.5 in the upper respiratory tract for the patients with heart failure：an elementary CFD study [J]. Biomed Eng Online，2016，15（Suppl 2）：138.
[13] 杨钊，张燕萍，桑田，等.临汾市大气PM10与5岁以下儿童呼吸系统疾病住院的浓度-反应关系研究[J].环境与健康杂志，2015，32（12）：1042-1049.
[14] Li N，Sioutas C，Cho A，et al. Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage [J]. Environ Health Perspect，2003，111（4）：455-460.
[15] Pettigrew MM，Gent JF，Revai K，et al. Microbial interactions during upper respiratory tract infections [J]. Emerg Infect Dis，2008，14（10）：1584-1591.
[16] Herbst T，Sichelstiel A，Schär C，et al. Dysregulation of allergic airway inflammation in the absence of microbial colonization [J]. Am J Respir Crit Care Med，2011，184（2）：198-205.
[17] Blainey PC，Milla CE，Cornfield DN，et al. Quantitative analysis of the human airway microbial ecology reveals a pervasive signature for cystic fibrosis [J]. Sci Transl Med，2012，4（153）：153ra130.
[18] 刘龙成，贺洪，范晓星，等.PM2.5影响有氧适能的研究综述[J].当代体育科技，2015，5（33）：243.
[19] 郑露露.基于组学数据挖掘的微生物检测、基因组注释及与宿主相互作用的研究[D].武汉：华中科技大学，2014.
[20] 肖纯凌，韩秀珍，席淑华，等.大气污染对儿童上呼吸道微生态影响的分析[J].中国公共卫生，2002，18（12）：1457-1458.
[21] Couzin-Frankel J. Bacteria and asthma：untangling the links [J]. Science，2010，330（6008）：1168-1169.
[22] Magnus MC，H?覽berg SE，Stigum H，et al. Delivery by cesarean section and early childhood respiratory symptoms and disorders：the Norwegian mother and child cohort study [J]. Am J Epidemiol，2011，174（11）：1275-1285.
[23] HEI Collaborative Working Group on Air Pollution，Poverty，Health in Ho Chi Minh City，Le TG，Ngo L，et al. Effects of short-term exposure to air pollution on hospital admissions of young children for acute lower respiratory infections in Ho Chi Minh City，Vietnam [J]. Res Rep Health Eff Inst，2012（169）：5-83
[24] Samoli E，Nastos PT，Paliatsos AG，et al. Acute effects of air pollution on pediatric asthma exacerbation： evidence of association and effect modification [J]. Environ Res，2011，111（3）：418-424.
[25] Guillam MT，Pédrono G，Le Bouquin S，et al. Chronic respiratory symptoms of poultry farmers and model-based estimates of long-term dust exposure [J]. Ann Agric Environ Med，2013，20（2）：307-311.
[26] 吴建军，刘宇坚，吴家刚，等.室内环境与学龄儿童呼吸系统健康的关联性研究[J].广州医学院学报，2012，40（3）：14-17.
[27] 周兰岛，解继胜，董光辉，等.百色市室内环境污染对儿童哮喘及哮喘样症状影响的流行病学调查[J].中国卫生统计，2013，30（3）：354-356.
[28] Wunderink RG，Waterer G. Advances in the causes and management of community acquired pneumonia in adults [J]. BMJ，2017.DOI：10.1136/bmj.j2471.
[29] Kan H，Wong CM，Vichit-Vadakan N，et al. Short-term association between sulfur dioxide and daily mortality： the Public Health and Air Pollution in Asia（PAPA）study [J]. Environ Res，2010，110（3）：258-264.
[30] 李航，郭伟丽，安珍，等.PM2.5对慢性阻塞性肺疾病影响研究进展[J].新乡医学院学报，2016，33（3）：234-238.
[31] 李盛，王金玉，王宇红，等.大气污染对兰州市城关区小学生肺通气功能的影响[J].环境与健康杂志，2015，32（6）：498-500.
[32] Ling SH，van Eeden SF. Particulate matter air pollution exposure：role in the development and exacerbation of chronic obstructive pulmonary disease [J]. Int J Chron Obstruct Pulmon Dis，2009，4：233-243.
[33] 中华医学会儿科学分会呼吸学组.反复呼吸道感染的临床概念和处理原则[J].中华儿科杂志，2008，46（2）：108-110.
[34] Dickson RP，Erb-downward JR，Martinez FJ，et al. The microbiome and the respiratory tract [J]. Annu Rev Physiol，2016，78（1）：481-504.
[35] Gollwitzer ES，Marsland BJ. Microbiota abnormalities in inflammatory airway diseases-Potential for therapy [J]. Pharmacol Ther，2014，141（1）：32-39.
[36] 徐春肖，马萍，胡晋婷，等.中药呼吸道微生态制剂发展现状[J].光明中医，2016，31（24）：3675-3677.
[37] Chen YS，Jan RL，Lin YL，et al. Randomized placebo-controlled trial of lactobacillus on asthmatic children with allergic rhinitis [J]. Pediatr Pulmonol，2010，45（11）：1111-1120.
[38] Nembrini C，Sichelstiel A，Kisielow J，et al. Bacterial-induced protection against allergic inflammation through a multicomponent immunoregulatory mechanism [J]. Thorax，2011，66（9）：755-763.
[39] 肖纯凌.大气污染与呼吸道微生态[M].北京：高等教育出版社，2012. |
|
|
|
