轻型复发性阿弗他溃疡患者铜锌血清含量的临床研究

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Abstract Objective To compare the serum content of iron and Copper Zinc in patients with minor recurrent aphthous ulcer (MiRAU) and healthy individuals, and then to analyze that whether there is a possible relationship between them and recurrent aphthous ulcer. Methods Ninty-seven patients with minor recurrent aphthous ulcer (MiRAU) confirmed in Department of Stomatology of Bethune International Peace Hospital (hereinafter referred to as "our hospital") from March 2015 to December 2016 and 102 healthy persons without MiRAU in our hospital were enrolled. The patients with MiRAU (group A) and healthy persons (group B) were extracted 5 mL fasting venous blood respectively, and then the chromaticity method was used to detect the serum concentration of Copper and Zinc irons in subjects. Results The serum content of Copper iron in those subjects of group A and group B were (16.77±3.89) μmol/L and (17.62±3.05) μmol/L, and there was no significant difference between the two groups (P ＞ 0.05). The serum content of Zinc iron in those subjects of group A [(14.39±1.86)μmol/L] was significantly lower than that of group B [(16.18±2.46) μmol/L](P ＜ 0.05). Conclusion The decrease of serum content of Zinc iron may be associated with recurrent aphthous ulcer.

Key words： Recurrent aphthous ulcer Copper Zinc Colorimetric measurement method

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	ZHANG Zichuan1 WANG Hongyan2 CHEN Guang1 WU Zhongyin1 FANG Huiqing1

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ZHANG Zichuan1 WANG Hongyan2 CHEN Guang1 WU Zhongyin1 FANG Huiqing1. A clinical study of the serum content of copper iron and zinc iron in patients with minor recurrent aphthous ulcer[J]. 中国医药导报, 2018, 15(6): 114-117.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2018/V15/I6/114

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