|
|
|
| Clinical study of percutaneous vertebroplasty combined with hypothermia plasma ablation in the treatment of thoracolumbar metastasis |
| LENG Yankui HOU Liqiang CAO Zhiqiang WANG Qiang WANG Haomin |
| Department of Orthopedics, Zhejiang Jinhua Guangfu Hospital, Zhejiang Province, Jinhua 321000, China |
|
|
|
Abstract Objective To explore the clinical effect of percutaneous vertebroplasty combined with hypothermia plasma ablation in the treatment of thoracolumbar metastasis. Methods A total of 20 patients with malignant tumor thoracolumbar metastasis diagnosed by clinical imaging and pathology in Department of Orthopedics, Zhejiang Jinhua Guangfu Hospital from January 2010 to June 2015 were selected, and they were treated with percutaneous minimally invasive vertebroplasty combined with hypothermia plasma ablation under local anesthesia. The visual analogue scale (VAS) before and after operation was compared, and the results of CT and X-ray were observed. Results All 20 cases gained successfull operation, they could move around by wearing a waist belt after operation for 2 h. They were followed-up for 12-30 months, with an average of 18 months. Postoperative thoracic waist pain was significantly reduced. The VAS score was reduced from (6.9±0.9) points before operation to (1.6±0.8) points after operation (P ＜ 0.05). The quality of life was improved significantly. The reexamination of CT and X-ray showed that the bone cement was filled satisfactorily, with no leakage. Conclusion Percutaneous vertebroplasty combined with hypothermia plasma ablation is a micro-invasive, effective palliative operation method for the malignant tumor patients with osteolytic metastatic lesion confined to the vertebral body, which can relieve pain, improve the quality of life, and reduce the recurrence of local lesions.
|
|
|
|
|
|
[1] 范晓莉.恶性肿瘤骨转移的诊断和治疗进展[J].临床合理用药，2009，6（2）：92-94.
[2] Gupta SP，Garg G. Curettage with cement augmentation oflarge bone defects in giant cell tumors with pathological fractures in lower-extremity long bones [J]. J Orthop Traumatol，2016，17（3）：239-247.
[3] 许宋锋，张鑫鑫，徐立，等.射频消融联合经皮椎体成形治疗脊柱转移瘤的临床应用[J].中国骨与关节杂志，2017， 6（2），119-122.
[4] 孟胜伟，蒋盛旦，蒋雷生.胸腰椎骨质疏松性椎体压缩性骨折椎体强化术后腰背痛原因的研究进展[J].脊柱外科杂志，2017，15（2）：117-122.
[5] Harrington KD. The use of polymethylmethacrylate for vertibral body replacement and anterior stabilization of pathological fracture dislocations of the spine due to metastatic malignant disease [J]. J Bone Joint Surg Am，1981，63（1）：36-46.
[6] Martin JB，Jean B，Sugui K，et al. Vertibroplasty：clinical experience and follow-up results [J]. Bone，1999，25：11-15.
[7] Murphy KJ，Deramond H. Percutaneous vertebroplasty in benign and malignant disease [J]. Neuroimaging Clin N AM，2000，10（3）：535-545.
[8] 刘宝军，裴斐，李继华，等.PVP术治疗胸腰椎转移癌的临床疗效观察[J].实用癌症杂志，2017，32（3）：499-500.
[9] 郭亮兵，张秀珍，潘玉林，等.经皮穿刺椎体成形术在多发性骨髓瘤所致椎体病理性骨折治疗中的疗效分析[J].肿瘤基础与临床，2017，30（2）：123-125.
[10] 王卫国，吴春根，程永德，等.射频消融术联合椎体成形术治疗脊柱转移性肿瘤[J].介入放射学杂志，2009，18（5）：262-364.
[11] 吴舜，赵伟.低温等离子消融治疗喉良恶性肿瘤的效果[J].广东医学，2016，37（S1）：114-115.
[12] Tokuhashi Y，Matsuzaki H，Oda H，et al. A revised scoring system for preoperative evaluation of metastatic spine tumor prognosis [J]. Spine，2005，30（19）：2186-2191.
[13] Tomita K，Kawahara N，Kobayashi L，et al. Surgical strategy for spinal metastases [J]. Spine，2001，26（3）：298-306.
[14] Ragel BT，Mendez GA，Reddington J，et al. Life expectancy and metastatic spine scoring systems：an academic institutional experience [J]. Clin Spine Surg，2017，30（8）：335-342.
[15] Tokuhashi Y，Uei H，Oshima M，et al. Scoring system for prediction of metastatic spine tumor prognosis [J]. World J Orthop，2014，5（3）：262-271. |
|
|
|
