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| Effect of Magong Qingjin Ningxiao Formula combined with Budesonide in the treatment of pediatric heat asthma#br# |
| YU Chen1 GU Renzhuang2 CUI Wencheng3 |
1.The First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Shandong Province, Jinan 250014, China;
2.College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Shandong Province, Jinan 250014, China;
3.Department of Pediatrics, Jinan Hospital of Traditional Chinese Medicine, Shandong Province, Jinan 250012, China |
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Abstract Objective To explore the therapeutic effect of Magong Qingjin Ningxiao Formula combined with Budesonide in the treatment of pediatric heat asthma and its effect on the percentage of neutrophils (NEUT%), C-reactive protein (CRP), eosinophils (EOS), and basophils (BASO). Methods A total of 120 child patients in the Pediatric Outpatient Department of Jinan Hospital of Traditional Chinese Medicine from July 2020 to February 2021 were selected as the research subjects, and they were divided into group A (60 cases) and group B (60 cases) by random number table method. Group A was treated with Budesonide inhalation. On the basis of group A, group B was given oral treatment of Magong Qingjin Ningxiao Formula. After treatment for one week, the clinical efficacy in both groups was evaluated, and the serum NEUT%, EOS, and BASO concentration variations of the two groups before and after treatment were observed. Results After treatment, the total effective rate of group B was higher than that in group A (P ＜ 0.05). After treatment, the serum NEUT%, CRP, EOS, and BASO concentrations in two groups were lower than those before treatment (P ＜ 0.05), which in the group B were lower than those in the group A (P ＜ 0.05). Conclusion Magong Qingjin Ningxiao Formula combined with Budesonide in the treatment of pediatric heat asthma can significantly improve airway inflammation and enhance immune function.
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