妊娠期合并HIV感染产妇不同分娩方式的分娩并发症及结局观察

Abstract
Figure/Table
References (25)
Related Citation (15)

Download: PDF (732 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To study the delivery complications and outcomes of different delivery modes of pregnant women with human immunodeficiency virus (HIV) infection. Methods A total of 106 pregnant women with HIV infection admitted to Liuzhou Maternity and Child Health Care Hospital, Guangxi Zhuang Autonomous Region from January 2018 to January 2020 were selected. According to different delivery modes, they were divided into observation group (caesarean section, 50 cases) and control group (vaginal delivery, 56 cases). The levels of stress factors (plasma norepinephrine [NE], serum cortisol [Cor], and angiotensin Ⅱ [AngⅡ] ) were compared between two groups at 12 h after delivery and before delivery; the duration of labor, delivery complications and adverse pregnancy outcomes were compared between two groups; Apgar score at 1, 3 min, and 5 min after delivery and birth weight were compared between two groups. Results At 12 h postpartum, the levels of NE, Cor, and AngⅡin two groups were higher than those before delivery, and observation group was higher than control group, and the differences were statistically significant (P < 0.05). The total delivery time in observation group was shorter than that in control group, and the difference was statistically significant (P < 0.05). The total incidence of delivery complications in observation group was higher than that in control group, and the difference was statistically significant (P ＜ 0.05). The total incidence of adverse pregnancy outcomes in observation group was lower than that in control group, and the different was statistically significant (P ＜ 0.05). Apgar scores of 3 and 5 min after delivery in two groups were lower than those of 1 min after delivery; Apgar scores of 5 min after delivery in two groups were lower than those of 3 min after delivery, and the differences were statistically significant (P < 0.05). Apgar scores of 1, 3 min, and 5 min after delivery showed no significant difference between two groups (P > 0.05). Conclusion Vaginal delivery can reduce the stress response and delivery complications of pregnant women with HIV infection, but the cesarean section can shorten the delivery time and reduce the risk of neonatal HIV infection.

Key words： Gestational period Human immunodeficiency virus Delivery mode Delivery complications Pregnancy outcome

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	WU Wei SHI Yue WU Yubi▲

Cite this article:

WU Wei SHI Yue WU Yubi▲. Observation on delivery complications and outcomes of different delivery modes of pregnant women with HIV infection#br#[J]. 中国医药导报, 2021, 18(32): 100-103,116.

URL:

https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2021/V18/I32/100

[1] 李艺，张黎，肖江，等.北京地区人类免疫缺陷病毒感染者合并乙型肝炎病毒感染的流行病学特征及影响因素分析[J].中华内科杂志，2021，60（3）：233-238.
[2] 黄海樱，陈波，周强，等.广州地区梅毒与人类免疫缺陷病毒感染血清学检测的流行病学调查[J].中华医院感染学杂志，2016，26（3）：549-551.
[3] Hamze H，Ryan V，Cumming E，et al. Human immunodeficiency virus seropositivity and early syphilis stage associated with ocular syphilis diagnosis：A Case-control Study in British Columbia，Canada，2010-2018 [J]. Clin Infect Dis，2019，71（2）：259-266.
[4] Bozorgomid A，Hamzavi Y，Khayat SH，et al. Pneumocystis jirovecii pneumonia and human immunodeficiency virus co-infection in Western Iran [J]. Iran J Public Health，2019， 48（11）：2065-2069.
[5] 刘春.某院2015—2017年HIV感染孕产妇的流行病学资料及妊娠结局分析[J].传染病信息，2018，31（3）：276-279.
[6] 何丹，蒲杰，刘伟信，等.四川省HIV感染孕产妇所生围产儿死亡现状与影响因素研究[J].中华流行病学杂志，2020，41（10）：1686-1691.
[7] 白秀丽，陈丹青，喻剑华，等.HIV孕妇应用HAART疗法对新生儿的疗效和安全性[J].中华临床感染病杂志，2020，13（6）：419-424.
[8] 高菊，王青，张建波，等.云南省某医院HIV/AIDS患者死亡危险因素分析[J].国际流行病学传染病学杂志，2021， 48（2）：129-132.
[9] 刘春华，耿杰，闫江舟，等.2015-2018年郑州市HIV抗体检测阳性孕产妇流行病学分析与母婴传播阻断效果[J].中国计划生育学杂志，2020，28（9）：1355-1367.
[10] 温春燕，李丽雅，李永红，等.母婴传播感染人类免疫缺陷病毒患儿抗反转录病毒治疗后的抗体转阴和临床特征分析[J].中华传染病杂志，2021，39（5）：300-303.
[11] Johnson CM，Bortnick SJ，Crawford PC，et al. Unique susceptibility of the fetal thymus to feline immunodeficiency virus infection：an animal model for HIV infection in utero [J]. Am J Reprod Immunol，2015，45（5）：273-288.
[12] 王慧，张欢欢.妊娠期HIV感染者的分娩方式和母婴结局分析[J].中国性科学，2017，26（6）：152-154.
[13] Yang M，Qin Q，Fang Q，et al. Cesarean section to prevent mother-to-child transmission of hepatitis B virus in China：A meta-analysis [J]. BMC Pregnancy Childbirth，2017，17（1）：303.
[14] Shokrpour M，Reza P，Sharifi M，et al. Prevalence of cesarean section and analysis of neonatal Apgar score and the mean time of second phase of labor in pregnant women [J]. Med Arch，2019，73（6）：399-403.
[15] Zhang J，Geerts C，Hukkelhoven C，et al. Caesarean section rates in subgroups of women and perinatal outcomes [J]. BJOG，2016，123（5）：754-761.
[16] 应海燕，徐平.不同分娩方式在瘢痕子宫再次妊娠产妇炎性状态与应激状态的影响比较[J].河北医学，2016， 22（10）：1687-1689.
[17] 郭玲玲，郑娟，汪美香.剖宫产产妇的术前焦虑情绪对其应激反应及术后疼痛的影响研究[J].中国妇幼保健，2020，35（6）：1126-1128.
[18] 刘伟，陈求珠，杨瑰艳，等.耳穴贴压联合个性化音乐疗法对初产妇围手术期应激反应的影响[J].中国针灸，2019， 39（8）：827-831.
[19] 乔亚萍，王潇滋，王前，等.凉山彝族自治州2011-2016年HIV感染孕产妇抗病毒治疗及影响因素分析[J].中国艾滋病性病，2019，25（12）：1206-1210.
[20] 汤柳英，张畅斌，高爽，等.广东省2014-2017年HIV感染孕产妇及暴露婴儿流行病学特征分析[J].中华流行病学杂志，2019，40（11）：1392-1397.
[21] Nguefack F，Ndombo PK，Ngoh R，et al. Risks associated with mother-to-child transmission of HIV infection [J]. Turk J Pediatr，2017，59（4）：426-433.
[22] 沈蕊，潘晓平，王爱玲，等.HIV感染孕产妇抗病毒药物耐药现状及影响因素研究进展[J].中国艾滋病性病，2020，26（5）：107-110.
[23] Goodenough CJ，Patel K，Van Dyke RB. Is there a higher risk of mother-to-child transmission of HIV among pregnant women with perinatal HIV infection? [J]. Pediatr Infect Dis J，2018，37（12）：1267-1270.
[24] 田一梅，梁梅馨，宋俊敏，等.2009-2018年深圳市HIV阳性孕产妇特点及母婴阻断效果分析[J].中国艾滋病性病，2020，26（3）：264-267.
[25] 武玉蓉.妊娠期合并HIV感染产妇经不同分娩方式生产的分娩结局对比及对产妇并发症、新生儿预后的影响[J].中国妇幼保健，2019，34（14）：3221-3223.