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| Significant of serum albumin, prealbumin, retinol binding protein and transferrin in postoperative parenteral nutrition support of gastric cancer |
| LIU Huilin1 ZHANG Dan2 DENG Xiangzhu3 LUN Limin2 |
1.Department of Clinical Laboratory Diagnostics Qingdao University Clinical Medical College, Shandong Province, Qingdao 266000, China;
2.Department of Clinical Laboratory, the Affiliated Hospital of Qingdao University, Shandong Province, Qingdao 266000, China;
3.Department of Clinical Laboratory, Qingdao Salt Worker′s Hospital, Shandong Province, Qingdao 266000, China |
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Abstract Objective To study the nutritional monitoring value of serum albumin (ALB), prealbumin (PA), retinol binding protein (RBP), and transferrin (TRF) in parenteral nutrition support for patients after gastric cancer surgery. Methods From June 2016 to June 2017, 80 patients with gastric cancer surgery stayed in the Gastrointestinal Surgery, the Affiliated Hospital of Qingdao University were selected, and they were started with total parenteral nutrition (TPN) (≥5 d) on the first day after gastric cancer surgery. The serum specimen of blood routine examinations on the day of hospital admission (before surgery), on the first day and the sixth day after surgery were collected respectively, and changes of ALB, PA, RBP and TRF level in serum were measured respectively as well. Results ①Concentration changes of ALB, PA, RBP and TRF before surgery, on the first day after surgery and the sixth day after surgery were comparerd, the differences were statistically significant (P < 0.01). ②On the first day after surgery, ALB, PA, RBP and TRF dropped compared with before surgery, the differences were statistically significant (P < 0.01). ③On the sixth day after surgery, ALB, PA, RBP and TRF climbed up compared with the first day after surgery, the differences were statistically significant (P < 0.01). ④On the sixth day after surgery, PA and RBP were compared with before surgery, the differences were not statistically significant (P > 0.05), and ALB and TRF were compared with before surgery, the differences were statistically significant (P < 0.05). Conclusion Serum ALB, PA, RBP and TRF can reflect patients′ nutritional status and they play a guiding role in parenteral nutrition support for patients after gastric cancer surgery.
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