|
|
Effect of PASE in the treatment of simple grade Ⅲ and Ⅳ traumatic splenic rupture with hemorrhagic shock and its influence on immune function #br# |
ZHANG Yuxin YAN Jinliang TIAN Jingzhong |
Department of Emergency Surgery, Bozhou People’s Hospital, Anhui Province, Bozhou 236800, China |
|
|
Abstract Objective To investigate the effect of partial splenic artery embolization (PASE) in the treatment of simple grade Ⅲ and Ⅳ traumatic splenic rupture with hemorrhagic shock and its influence on immune function. Methods The clinical data of 86 patients with simple grade Ⅲ and Ⅳ traumatic splenic rupture complicated with hemorrhagic shock admitted to Bozhou People’s Hospital of Anhui Province from June 2017 to December 2020 were retrospectively analyzed, according to the operation method, they were divided into observation group and control group, with 43 cases in each group. The control group was treated with traditional surgery, and the observation group was treated with PASE. The perioperative situation, the changes of T lymphocyte subsets (CD3+, CD4+, CD4+/CD8+), and the incidence of complications were compared between the two groups. Results The operation time, systolic blood pressure recovery time, ambulation time, and hospitalization time in the observation group were shorter than those in the control group, and the intraoperative blood loss of the observation group was less than those in the control group, and the differences were statistically significant (P < 0.05); the differences of CD3+, CD4+, CD4+/CD8+ between the two groups, time point and interaction compared were statistically significant (P < 0.05); the total incidence of complications the obseruation group was lower than that of the control group (P < 0.05). Conclusion PASE in treatment of simple grade Ⅲ and Ⅳ traumatic splenic rupture with hemorrhagic shock have obvious effect, which is worth promoting.
|
|
|
|
|
[1] 丁鑫良,钟建,张兆金.CT在创伤性脾破裂中的临床诊断价值[J].中国当代医药,2019,26(10):169-171.
[2] Fegan D. Splenic rupture [J]. Clin Med(Lond),2019,19(2):188-189.
[3] 甘家兵.脾切除术后联合大网膜自体脾片种植治疗外伤性脾破裂的临床效果分析[J].中国现代医生,2019,57(32):45-47.
[4] 贾守洪,鲁旭,毛熙贤,等.腹腔镜脾切除术联合自体血回输治疗外伤性脾破裂的临床体会[J].腹腔镜外科杂志,2019,24(8):574-576,592.
[5] 周志涛,范隼,何伟良,等.腹腔镜脾切除术在外伤性脾破裂中的应用价值[J].中华肝脏外科手术学电子杂志,2019,8(6):522-526.
[6] 肖琳,姜淮芜,欧荣册.射频消融术与传统手术治疗外伤性脾破裂的临床效果比较[J].解放军医药杂志,2020,32(1):64-67.
[7] Kang BH. Splenic Liquefaction after Splenic Artery Embolization [J]. Acute Crit Care,2019,34(1):92-94.
[8] 沈贵虎,崔宇.单纯创伤性脾破裂合并失血性休克患者应用选择性脾动脉栓塞术治疗的效果分析[J].检验医学与临床,2020,17(16):2405-2407.
[9] 中华医学会外科学分会脾功能与脾脏外科学组.脾脏损伤治疗方式的专家共识(2014版)[J].临床肝胆病杂志,2015,31(7):1002-1003.
[10] Dixon S,Horgan LF. The elusive spleen [J]. Ann R Coll Surg Engl,2019,101(3):176-179.
[11] 姜洪池,周孟华.脾脏外科临床研究进展与展望[J].中国实用外科杂志,2020,40(1):53-57,61.
[12] 中国医师协会介入医师分会急诊介入专业委员会,中国研究型医院学会出血专业委员会.创伤性脾出血介入治疗专家共识[J].介入放射学杂志,2020,29(7):641-649.
[13] 顾颖,呈卫华,孙春梅,等.胸腹部创伤合并出血性休克患者液体治疗的临床体会[J].山西医药杂志,2019,48(8):916-917.
[14] 王志华,顾东明,盛乐智,等.急诊创伤重点超声评估检查对腹部闭合性损伤患者诊断及休克预测价值[J].中国医学装备,2018,15(12):89-92.
[15] 李孔才,温海斌,李德,等.外伤性肝脾破裂致失血性休克液体复苏的诊治[J].深圳中西医结合杂志,2019,29(1):115-116.
[16] 周晓华,田由京,李合.脾修补术、部分切除术及动脉栓塞术治疗创伤性脾破裂的疗效以及对患者免疫功能的影响[J].创伤外科杂志,2020,22(3):175-180.
[17] 裴磊,李春明,黄涛,等.腹腔镜与传统脾切除术治疗创伤性脾破裂的疗效对比研究[J].腹腔镜外科杂志,2019, 24(8):577-581.
[18] 吴瑞克,陈新国,李霞.选择性脾动脉栓塞术治疗创伤性脾破裂伴休克的疗效分析[J].浙江创伤外科,2019, 24(3):472-473.
[19] 应青松,余文杰.选择性脾动脉栓塞术治疗创伤性脾破裂临床研究[J].浙江创伤外科,2019,24(6):1141-1142.
[20] 牟奇海,彭科,邱远,等.选择性脾动脉栓塞术对急诊外伤性脾破裂救治的效果探讨[J].局解手术学杂志,2020,29(5):410-413.
[21] 华明,杨红云,曹崇奇,等.选择性脾动脉栓塞术在外伤性脾破裂非手术治疗中的意义[J].南京医科大学学报:自然科学版,2019,39(8):1207-1210.
[22] 赵涛,陈秋星,王高生,等.两种手术方式治疗Ⅲ、Ⅳ级创伤性脾破裂伴休克的疗效比较[J].中华急诊医学杂志,2018,27(6):679-682.
[23] 张勃.单纯性Ⅲ,Ⅳ级创伤性脾破裂伴失血性休克患者的治疗方案探讨[J].中国实用医药,2020,15(6):54-56.
[24] 卢骏,夏婷,李磊,等.脾动脉介入栓塞治疗外伤性脾破裂的临床效果及对患者免疫功能的影响[J].现代生物医学进展,2019,19(10):1937-1940,1952.
[25] 段磊,谢静,王石,等.脾脏保留手术对外伤性脾破裂患者免疫功能的影响[J].现代生物医学进展,2019,19(18):3511-3514,3549. |
|
|
|