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| Research progress on pyroptosis and its role in atherosclerosis#br# |
| XU Lu1 WANG He2 YUE Ke1 WEI Ke1 XIE Jinhong2 GUAN Huaimin2 |
1.The First Clinical Medical College, Henan University of Chinese Medicine, Henan Province, Zhengzhou 450000, China;
2.Ward Three, Department of Cardiovascular Medicine, the First Affiliated Hospital of Henan University of Chinese Medicine, Henan Province, Zhengzhou 450000, China |
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Abstract Pyroptosis is a new type of programmed cell death, which is significantly different in form from traditional cell death such as apoptosis and necrosis. Atherosclerotic cardiovascular disease seriously affects the physical and mental health of residents. Recent studies have found that vascular endothelial cells, macrophages and smooth muscle cells all experience pyroptosis, which affects the development process of atherosclerosis. This article intends to review the relationship between pyroptosis and atherosclerosis, in order to provide new ideas and find new directions for the treatment of cardiovascular diseases.
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