保留盆腔自主神经的根治性子宫切除术对中年宫颈癌患者术后生活质量的影响

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Abstract Objective To analyze the effect of laparoscopic nerve sparing radical hysterectomy (LNSRH) with pelvic autonomic nerve preservation on postoperative quality of life in middle-aged patients with cervical cancer and to explore its clinical value. Methods One hundred and seventy-three cases of middle age cervical cancer treated in the Southwest Hospital of Army Military Medical University from July 2014 to July 2016 were analyzed retrospectively. According to the surgical procedure for the treatment of patients, 89 cases received LNSRH were included into the LNSRH group, while 84 patients treated with the conventional laparoscopic radical hysterectomy (LRH) were enrolled into LRH group. The situation of operation, recovery and complications of patients were compared between the two groups, and the cervical cancer function evaluation system (FACT-Cx) was used to evaluate the changes of life quality before and 6 months after surgery. Results The operative time in LNSRH group was longer than that in LRH group, and the difference was statistically significant (P < 0.05). There was no significant difference in the amount of bleeding and lymph node dissection between the two groups (P > 0.05). The indwelling time, residual urine volume, exhaust time and defecation time of LNSRH group were all lower than that in LRH group, and the differences were statistically significant (P < 0.05). The incidence of urinary retention in LNSRH group was lower than that in LRH group, and the difference was statistically significant (P < 0.05). In LNSRH group, there was no significant change in quality of life 6 months after operation (P > 0.05). The scores of additional attention items and FACT-Cx total score 6 months after operation in LRH group were significantly lower than those in preoperative group (P < 0.05). Conclusion The LNSRH surgery can effectively avoid pelvic nerve injury, shorten the postoperative function recovery of bowel and bladder, reduce postoperative complication risk and mitigate the adverse effects of surgery on the quality of life, is a safe and effective operation, worthy of promotion.

Key words： Cervical cancer Pelvic autonomic nerve Radical hysterectomy Quality of life

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	LENG Shaohua1 WANG Yanzhou2 ZHAO Xiaolan3▲

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LENG Shaohua1 WANG Yanzhou2 ZHAO Xiaolan3▲. Effect of radical hysterectomy with preservation of pelvic autonomic nerve on postoperative quality of life in patients with middle aged cervical cancer[J]. 中国医药导报, 2018, 15(5): 84-88.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2018/V15/I5/84

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