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Influencing factors of unplanned withdrawing machine in patients with severe CRRT in ICU#br# |
CHEN Jincan SONG Min YANG Shunyin▲ |
Intensive Care Unit, Lu’an Hospital of Anhui Medical University (Lu’an People’s Hospital), Anhui Province, Lu’an 237000, China |
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Abstract Objective To observe the influencing factors of unplanned withdrawing of patients with continuous renal replacement therapy (CRRT) in the intensive care unit (ICU). Methods The clinical data of 80 CRRT patients admitted to the hospital from January 2017 to January 2020 were retrospectively analyzed, and baseline data were collected. According to the occurrence of unplanned withdrawing, patients were divided into unplanned and planned withdrawing units, and logistic regression analysis was used to test the influencing factors of unplanned disengagement. Results Among 80 CRRT patients, a total of 35 cases (43.75%) were unplanned withdrawing, and another 45 cases (56.25%) were planned withdrawing. The blood flow rate of the unplanned withdrawing unit was lower than that of the planned withdrawing unit, and the volume ratio of venous ampulla embolism, hematocrit, therapeutic dose, and prothrombin time activity (PTA) were higher than those of the planned unit, and the differences were statistically significant (P < 0.05). Logistic regression analysis showed that slow blood flow, high volume ratio of venous ampulla embolism, high hematocrit, high therapeutic dose, and high PTA were the risk factors for unplanned withdrawing of ICU patients with severe CRRT (OR > 1, P < 0.05). Conclusion The risk of unplanned withdrawing machine in patients with severe CRRT in ICU is high, the risk factors of unplanned withdrawing machine include slow velocity of blood flow, high volume ratio of jugular embolization, high packet cell volume, high therapeutic dose and high PTA.
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[1] 黄蓉双,张凌,付平.精准连续性肾脏替代治疗——2017急性透析质量倡议指南解读[J].华西医学,2018,33(7):831-834.
[2] 李强,苗世敏.连续性肾脏替代治疗与间歇性血液透析治疗在急性肾衰竭中的治疗效果比较[J].中国中西医结合肾病杂志,2018,19(1):70-72.
[3] 赵宇亮,买红霞,付平.连续性肾脏替代治疗应用于急性肾损伤的时机选择[J].华西医学,2018,33(7):806-809.
[4] Stads S,Kant KM,Jong MFC,et al. Predictors of short-term successful discontinuation of continuous renal replacement therapy:results from a prospective multicentre study [J]. BMC Nephrol,2019,20(1):129.
[5] 王美力,叶燕红,杨静,等.护理质控小组管理对连续性肾脏替代疗法患者非计划下机率及非计划拔管率的影响[J].山西医药杂志,2020,49(9):1171-1173.
[6] 郝桂华,胡敏,黄洁,等.故障模式与影响分析在连续性肾脏替代治疗非计划性下机中的应用[J].中国实用护理杂志,2018,34(26):2027-2031.
[7] 陈香美.临床诊疗指南·肾脏病学分册[M].北京:人民卫生出版社,2001:204-205.
[8] 方秀花,梅本刚.连续性肾脏替代治疗非计划性下机原因分析及护理对策[J].重庆医学,2016,45(27):3881-3883.
[9] 陈香美.血液净化标准操作规程[J].中华护理杂志,2015, 50(1):57-61.
[10] Tandukar S,Palevsky PM. Continuous Renal Replacement Therapy:Who,When,Why,and How [J]. Chest,2019, 155(3):626-638.
[11] 邬步云,余燕婷,季大玺.连续性肾脏替代治疗在中国的发展历程与展望[J].中国血液净化,2019,18(9):587-590.
[12] Karkar A. Continuous renal replacement therapy:Principles,modalities,and prescription [J]. Saudi J Kidney Dis Transpl,2019,30(6):1201-1209.
[13] 张仲华,曾铁英,徐蓉,等.无抗凝连续性肾脏替代治疗非计划性下机相关因素分析[J].护士进修杂志,2019, 34(18):1633-1639.
[14] 查丽玲,周松,江榕.ICU行枸橼酸抗凝CRRT病人非计划性下机影响因素研究[J].护理研究,2018,32(18):2926-2930.
[15] 米雪纯,田莹,马雪芩,等.连续性肾脏替代治疗体外循环患者凝血危险因素及干预措施研究进展[J].海南医学,2018,29(19):2791-2794.
[16] 王圆圆.ICU行枸橼酸抗凝连续性肾脏替代治疗病人非计划性下机影响因素研究[J].血栓与止血学,2020, 26(1):61-63.
[17] 张仲华,曾铁英,黄博伦,等.无抗凝连续性肾脏替代治疗体外循环装置使用时间影响因素的研究[J].护理学杂志,2019,34(13):22-27.
[18] 李克佳,付月亿,王欢,等.连续性肾脏替代治疗体外循环凝血的影响因素及预防对策研究进展[J].中国血液净化,2018,17(2):129-132.
[19] 吴媛,张明,王小闯,等.局部枸橼酸抗凝的连续肾脏替代治疗在脑出血并发急性肾损伤患者中的应用效果[J].中国医药,2019,14(9):1370-1374.
[20] 王秀哲,石海鹏,张晶敏,等.重症患者无肝素CRRT中滤器凝血的高危因素分析[J].中国中西医结合肾病杂志,2018,19(9):782-784.
[21] 陆伟,燕宪亮,刘丽,等.局部枸橼酸抗凝与全身肝素抗凝在ARDS并发AKI患者CRRT治疗中的效果比较[J].中国医药导报,2020,17(32):152-155.
[22] 胡超,应双伟,包玫瑰,等.CRRT治疗ICU脓毒症患者的临床效果[J].中国现代医生,2021,59(2):22-25.
[23] 张族勤.脓毒症急性肾损伤连续性肾脏替代治疗中尿量变化对预后的影响[J].中国医药科学,2021,11(12):178-182.
[24] 梁华般,董伟,李志莲,等.连续性肾脏替代治疗剂量在急性肾损伤中的研究与应用进展[J].临床肾脏病杂志,2018,18(5):260-262.
[25] 冯晓娟,朱旭生,罗秋凤.不同CRRT治疗方案在脓毒症并发肾损伤患者中的疗效对比[J].国际泌尿系统杂志,2018,38(3):464-467.
[26] 张斌,陈明迪,郜琨,等.组合血液净化对多脏器功能障碍合并肝衰竭患者疗效[J].中华急诊医学杂志,2018, 27(9):1010-1014.
[27] 莫曼秋,潘玲,严官强,等.凝血指标与脓毒症相关急性肾损伤患者全因死亡的相关性分析[J].中华肾脏病杂志,2019,35(10):758-764.
[28] Dager WE,Gulseth MP,Nutescu EA.抗凝治疗医护指南[M].北京:人民卫生出版社,2012:11-24. |
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