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Application of hysteroscopy in diagnosis and management of gestational trophoblastic disease |
YANG Shuli WU Yumei LI WEI TIAN Ming MIAO Jinwei▲ |
Department of Gynecologic Oncology, Bejing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100006,China |
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Abstract Objective To study the value of diagnosis and treatment with hysteroscopy for gestational trophoblastic disease. Methods From January 2013 to January 2017, clinical data of 69 patients with GTD were admitted to Department of Gynecologic Oncology, Beijing Obstetrics and Gynecology Hospital, and underwent hysteroscopy was retrospectively analyzed. The and outcome of these patients were reviewed. Results Among these 69 patients, 42 cases were confirmed Hydatidiform moles, 5 cases underwent the first hysteroscopy and curettage, 37 cases underwent hysteroscopy and curettage again. None was residue after curettage. 27 cases were confirmed with GTN including invasive mole in 24 cases, choriocarcinoma in 2 cases, PSTT in 1 case. All the GTN except 1 patient with PSTT achieved complete remission by standard chemotherapy. 1 patient with PSTT was cured by lesion excision. No recurrence was fund in all the GTN patients. Conclusion Selective curettage of residual trohpoblastic tissue directed by hysteroscopy is safe and effective. Hysteroscopy is an effective alternative of diagnosis for GTN, and no effects on the prognosis.
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