针刺治疗痰浊闭阻证稳定型心绞痛患者的效果

Abstract
Figure/Table
References (29)
Related Citation (14)

Download: PDF (509 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To investigate the clinical effect of acupuncture on patients with stable angina pectoris with syndrome of blockade of phlegm-turbidity and its effect on serum lipoprotein-associated phospholipase A2 (Lp-PLA2) level. Methods A total of 116 patients with stable angina pectoris with syndrome of blockade of phlegm-turbidity admitted to the Department of Cardiology, the Second Affiliated Hospital of Shenyang Medical College from October 2018 to June 2020 were selected as the research objects. They were divided into Western medicine control group and acupuncture treatment group by random number table method, with 58 patients in each group. The Western medicine control group was treated with conventional Western medicine such as coronary artery dilation, anti-platelet aggregation and reducing lipid to stabilize plaque, while the acupuncture treatment group was treated with acupuncture on the basis of the Western medicine control group. Both groups received continuous treatment for 12 weeks. The changes of traditional Chinese medicine syndrome score, Seattle angina questionnaire score, electrocardiogram treadmill exercise test, serum lipid and Lp-PLA2 levels were compared between the two groups. Results The clinical effective rate of traditional Chinese medicine syndrome in acupuncture treatment group was higher than that in Western medicine control group (P ＜ 0.05). After treatment, Seattle angina questionnaire score and electrocardiogram treadmill exercise test index were significantly higher than before treatment (P ＜ 0.05). Traditional Chinese medicine syndrome score and serum levels of triacylglycerol (TAG), total cholesterol (TC), low density lipoprotein cholesterol (LDL-C) and Lp-PLA2 were significantly decreased compared with those before treatment (P ＜ 0.05). Compared with the Western control group, the Seattle angina questionnaire score and electrocardiogram treadmill exercise test index in the acupuncture treatment group after treatment were significantly increased (P ＜ 0.05), and the traditional Chinese medicine syndrome score and levels of serum TAG, TC, LDL-C, and Lp-PLA2 were significantly decreased (P ＜ 0.05). Conclusion The clinical effect of acupuncture on patients with stable angina pectoris with syndrome of blockade of phlegm-turbidity is significant, which can effectively improve the clinical symptoms, improve the quality of life and heart function, and reduce the levels of serum lipid and Lp-PLA2.

Key words： Stable angina pectoris Acupuncture therapy Syndrome of blockade of phlegm-turbidity Lipoprotein-associated phospholipase A2

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	SUN Yan1 LI Bohui2 WANG Zelin3

Cite this article:

SUN Yan1 LI Bohui2 WANG Zelin3. Effect of acupuncture on patients with stable angina pectoris with syndrome of blockade of phlegm-turbidity#br#[J]. 中国医药导报, 2021, 18(29): 68-72.

URL:

https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2021/V18/I29/68

[1] Farmakis D，Andrikopoulos G，Giamouzis G，et al. Practical recommendations for the diagnosis and medical management of stable angina：an expert panel consensus [J]. J Cardiovasc Pharmacol，2019，74（4）：308-314.
[2] Zhao L，Li D，Zheng H，et al. Acupuncture as adjunctive therapy for chronic stable angina：a randomized clinical trial [J]. JAMA Intern Med，2019，179（10）：1388-1397.
[3] Ferrari R，Camici PG，Crea F，et al. Expert consensus document：A ’diamond’ approach to personalized treatment of angina [J]. Nat Rev Cardiol，2018，15（2）：120-132.
[4] Neumann FJ，Sousa-Uva M，Ahlsson A，et al. 2018 ESC/EACTS Guidelines on myocardial revascularization [J]. EuroIntervention，2019，14（14）：1435-1534.
[5] 周健华，黄伟，邓杰，等.针刺对稳定型心绞痛治疗效果的Meta分析[J].湖北中医药大学学报，2018，20（6）：38-41.
[6] 中华医学会心血管病学分会，中华心血管病杂志编辑委员会.慢性稳定性心绞痛诊断与治疗指南[J].中华心血管病杂志，2007，35（3）：195-206.
[7] 中华中医药学会心血管病分会.冠心病稳定型心绞痛中医诊疗专家共识[J].中医杂志，2018，59（5）：447-450.
[8] 梁繁荣，王华.针灸学（新世纪第四版）[M].北京：中国中医药出版社，2016：62-65.
[9] 中华人民共和国卫生部.中药新药临床研究指导原则（试行）[M].北京：中国医药科技出版社，2002：69-73.
[10] Lassen JF，Burzotta F，Banning AP，et al. Percutaneous coronary intervention for the left main stem and other bifurcation lesions：12th consensus document from the European Bifurcation Club [J]. Eurointervention，2017，13（13）：1540-1553.
[11] 杨若男，李洪伟，张茗.李敬孝教授治疗稳定型心绞痛的经验[J].中国中医急症，2019，28（8）：1488-1490.
[12] 景苗苗，兰颖，孙睿睿，等.浅议循经取穴治疗慢性稳定型心绞痛[J].世界中医药，2015，10（4）：490-493.
[13] 王洁，胡玲，刘磊，等.针刺神门穴对心脏功能影响研究进展[J].实用中医药杂志，2015，31（1）：77-78.
[14] 王悦，陈波.针刺内关穴治疗冠心病心绞痛的研究概况[J].中医药临床杂志，2016，28（6）：889-891.
[15] 常成成，袁国强，魏聪，等.脉络学说营卫理论指导冠心病心绞痛辨证论治[J].疑难病杂志，2019，18（8）：837-840，846.
[16] 吴召敏，顾一煌.从调神止痛理论探讨内关穴治疗痛症[J].中医药信息，2020，37（1）：36-41.
[17] 杨志虹，张宁，孙佳，等.运用西雅图量表评价循经取穴治疗慢性稳定性心绞痛的疗效观察[J].中华中医药杂志，2019，34（8）：3838-3842.
[18] 张晓红，何平，王科程，等.运动平板试验诊断冠心病诊断价值研究[J].临床军医杂志，2018，46（5）：588-589.
[19] 潘立江.针灸联合盐酸曲美他嗪片治疗不稳定型心绞痛临床观察[J].上海针灸杂志，2019，38（10）：1103-1108.
[20] 董竞方，马晓昌.双参宁心颗粒治疗气虚血瘀型稳定型心绞痛疗效观察[J].西部中医药，2019，32（1）：70-73.
[21] 叶欣，李结华.血清脂蛋白相关磷脂酶A2水平与冠状动脉病变程度的相关性[J].临床医学，2019，39（8）：1-4.
[22] 王凌，谢伟贤，邓爱红.血浆脂蛋白相关磷脂酶A2水平在冠心病患者严重程度评估中的应用价值[J].慢性病学杂志，2019，20（3）：358-360.
[23] 陈运龙，卞士柱，刘小燕，等.稳定型冠心病合并糖尿病患者循环脂蛋白相关磷脂酶A2水平对左心功能的预测价值[J].临床心血管病杂志，2020，36（10）：900-906.
[24] 唐龙.Lp-PLA2在顽固性高血压患者中的表达及其临床意义[J].检验医学与临床，2021，18（2）：210-213.
[25] 李志红，申强.脂蛋白相关磷脂酶A2与动脉粥样硬化及冠心病关系的研究进展[J].中国当代医药，2020，27（31）：21-25.
[26] 张才.Lp-PLA2、Aβ1-40血清水平变化与CHD患者冠脉病变严重程度的相关性分析[J].湖南师范大学学报：医学版，2020，17（6）：204-207.
[27] 蔡裕福.人血浆脂蛋白相关磷脂酶A2活性和冠脉病变严重程度的关系[J].中国现代医生，2020，58（12）：30-32.
[28] 陈红兵，刘振宗.血清Lp-PLA2、hs-CRP与骨钙素在冠心病中的诊断价值[J].中国卫生标准管理，2020，11（23）：61-64.
[29] 张国瑞，张静，王立君，等.高血压合并心绞痛患者颈动脉内膜中膜厚度与脂蛋白相关磷脂酶A2、炎性因子、T淋巴细胞及血管内皮功能的关系研究[J].实用心脑肺血管病杂志，2020，28（11）：36-41.