HUCMSCs在脊髓损伤细胞移植应用中的研究进展

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Abstract Human umbilical cord mesenchymal stem cells (HUCMSCs) is a kind of totipotent stem cells with continuous self-renewal, which have strong ability to delay and transplant and less ethical controversy. Therefore, HUCMSCs have been widely promoted and applied. In the treatment of spinal cord injury, the use of HUCMSCs is a new biological therapy for spinal cord injury, which shows better therapeutic potential compared with conventional methods such as surgery, drugs, and rehabilitation. However, the therapeutic mechanism, optimal transplantation approach, and timing of HUCMSCs in spinal cord injury are still controversial. Therefore, based on the latest research progress of HUCMSCs in the treatment of spinal cord injury, this paper systematically summarizes the characteristics of HUCMSCs and the potential neural repair mechanism and application of HUCMSCs in spinal cord injury, providing a basis for the clinical transformation research of HUCMSCs transplantation in the future.

Key words： Human umbilical cord mesenchymal stem cell Spinal cord injury Cell transplantation

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	PAN Zhipeng LI Sicheng TANG Long YAO Liqing

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PAN Zhipeng LI Sicheng TANG Long YAO Liqing. Research progress of HUCMSCs in spinal cord injury cell transplantation#br#[J]. 中国医药导报, 2021, 18(29): 36-40.

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https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2021/V18/I29/36

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