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Progress in diagnosis and treatment of chronic inflammatory demyelinating polyneuropathy |
LI Qi1 ZHAO Dongjie1 WANG Yuhua1 DONG Sha1 CHANG Lei1 ZHANG Peng1 NI Yao2,3 |
1.Acupuncture and Massage Academy, Beijing University of Chinese Medicine, Beijing 100029, China;
2.Graduate School, Beijing University of Chinese Medicine, Beijing 100029, China;
3.Department of Infection, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China |
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Abstract Chronic inflammatory demyelinating polyneuropathy (CIDP) is an acquired immune-mediated peripheral neuropathy characterized by weakness and sensory disturbances that may be associated with other neurological disorders. In addition to the classic CIDP, there are many variants which easily lead to misdiagnosis, so that improving the diagnosis of variant CIDP is very important. Diagnosis usually incorporates clinical manifestations, electrophysiological examinations, and other supporting evidence, such as nerve biopsy, somatosensory evoked potential, cerebral spinal fluid examination, MRI and ultrasound support evidence, CIDP first-line treatment including corticosteroid (CS), intravenous immunoglobulin (IVIg), plasma exchange (PE) and immunosuppressive treatment. The purpose of this study is to review the clinical manifestations, diagnosis and treatment of CIDP.
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