|
|
Investigation on the fundus retinopathy with “fundus viscera syndrome differentiation” based on the combination of macro and micro syndrome differentiation |
LU Bingwen1,2 XIE Like2 WU Gaiping2 ZHAO Jian1 YUAN Hang2 |
1.Department of Ophthalmology, the University of Hong Kong, Hong Kong 999077, China;
2.Department of Ophthalmology, Eye Hospital, China Academy of Chinese Medical Sciences, Beijing 100000, China |
|
|
Abstract Because ancient traditional Chinese medicine (TCM) ophthalmologists are unable to see the fundus, traditional macroscopic syndrome differentiation and the holistic concept are greatly limited, so the curative effects of TCM therapies for retinal diseases are not ideal. With the rapid development of modern retinal imaging technology and modern biotechnology, ophthalmologists can clearly understand retinal morphological and functional changes, which makes it possible to differentiate retinal diseases microscopically. The comprehensive diagnosis and treatment mode of traditional macro-syndrome differentiation combined with micro-syndrome differentiation by modern medical technology is helpful to grasp the core pathogenesis and carry out precise treatment in the clinical practice of TCM ophthalmology. By using the new method of syndrome differentiation and treatment, combined with the classical ophthalmology five-wheel theory, syndrome differentiation of six channels theory and “inner five-wheel” hypothesis, the “fundus viscera syndrome differentiation” based on the combination of macro and micro syndrome differentiation is expected to become the modern syndrome differentiation system for fundus retinopathy, deepen the understanding of fundus retinopathy, and imove the clinical diagnosis and treatment level of TCM ophthalmologists.
|
|
|
|
|
[1] 沈自尹.微观辨证和辨证微观化[J].中医杂志,1986,27(2):55-57.
[2] 郭振球.微观辨证学的研究现状与发展趋势[J].中医药学刊,2013,21(5):645-646.
[3] 吴伟,王创畅,邓铁涛.“五诊十纲”中医临床新思维探讨[J].中医杂志,2014,55(6):455-457.
[4] 陈达夫.中医眼科六经法要[M].成都:四川人民出版社,1978:11-12.
[5] 邱礼新.“內五轮”假说在眼底病治疗中的应用[J].中国中医眼科杂志,2001,11(1):54-56.
[6] Hagan K,DuBose T,Cunefare D,et al. Multimodal handheld adaptive optics scanning laser ophthalmoscope [J]. Opt Lett,2020,45(17):4940-4943.
[7] Vira J,Marchese A,Singh RB,et al. Swept-source optical coherence tomography imaging of the retinochoroid and beyond [J]. Expert Rev Med Devices,2020,17(5):413-426.
[8] Battista M,Borrelli E,Sacconi R,et al. Optical coherence tomography angiography in diabetes:A review [J]. Eur J Ophthalmol,2020,30(3):411-416.
[9] Yao X,Alam MN,Le D,et al. Quantitative optical coherence tomography angiography:A review [J]. Exp Biol Med(Maywood),2020,245(4):301-312.
[10] Ashimatey BS,Green KM,Chu Z,et al. Impaired Retinal Vascular Reactivity in Diabetic Retinopathy as Assessed by Optical Coherence Tomography Angiography [J]. Invest Ophthalmol Vis Sci,2019,60(7):2468-2473.
[11] Pfau M,Jolly JK,Wu Z,et al. Fundus-controlled perimetry(microperimetry):Application as outcome measure in clinical trials [J]. Prog Retin Eye Res,2020,82:100907.
[12] Csaky KG,Patel PJ,Sepah YJ,et al. Microperimetry for geographic atrophy secondary to age-related macular degeneration [J]. Surv Ophthalmol. 2019,64(3):353-364.
[13] Pasmanter N,Petersen-Jones SM. A review of electroretinography waveforms and models and their application in the dog [J]. Vet Ophthalmol,2020,23(3):418-435.
[14] Zeng Y,He T,Liu J,et al. Bioinformatics analysis of multi-omics data identifying molecular biomarker candidates and epigenetically regulatory targets associated with retinoblastoma [J]. Medicine(Baltimore),2020,99(47):e23314.
[15] Chaiwiang N,Poyomtip T. Microbial dysbiosis and microbiota-gut-retina axis:The lesson from brain neurodegenerative diseases to primary open-angle glaucoma pathogenesis of autoimmunity [J]. Acta Microbiol Immunol Hung,2019,66(4):541-558.
[16] Huang JD,Curcio CA,Johnson M. Morphometric analysis of lipoprotein-like particle accumulation in aging human macular Bruch’s membrane [J]. Invest Ophthalmol Vis Sci,2008,49(6):2721-2727.
[17] Schlingemann RO. Role of growth factors and the wound healing response in age-related macular degeneration [J]. Graefes Arch Clin Exp Ophthalmol,2004,242(1):91-101.
[18] Grossniklaus HE,Ling JX,Wallace TM,et al. Macrophage and retinal pigment epithelium expression of angiogenic cytokines in choroidal neovascularization [J]. Mol Vis,2002,21(8):119-126.
[19] Zhang ZY,Bao XL,Cong YY,et al. Autophagy in Age-Related Macular Degeneration:A Regulatory Mechanism of Oxidative Stress [J]. Oxid Med Cell Longev,2020:2896036.
[20] 蒋鹏飞,彭俊,彭清华.浅析黄斑属脾[J].中国中医眼科杂志,2020,30(1):42-44,48.
[21] 陈丽.年龄相关性黄斑变性中医证型与多焦视网膜电图和血浆同型半胱氨酸及相关因素的关系研究[D].成都:成都中医药大学,2009:1-94.
[22] 孙馨馨,孙莎,史柏青,等.年龄相关性黄斑变性玻璃膜疣的F-10共焦激光扫描检眼镜retro-mode成像检查[J].国际眼科杂志,2017,17(9):1723-1726.
[23] 丁银银.年龄相关性黄斑变性黄斑厚度与中医辨证分型相关性的探讨[D].南京:南京中医药大学,2013:1-45.
[24] Rowan S,Jiang S,Chang ML,et al. A low glycemic diet protects disease-prone Nrf2-deficient mice against age-related macular degeneration [J]. Free Radic Biol Med,2020,150:75-86.
[25] 谢立科.中西医诊治视网膜静脉阻塞之管窥[J].中国中医眼科杂志,2020,30(5):303-307.
[26] 陆秉文,谢立科,赵健.基于“五轮八廓”学说治疗视网膜静脉阻塞之思路初探[J].中国中医眼科杂志,2021, 31(3):187-191. |
|
|
|