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Research progress in magnetic resonance imaging of pediatric obsessive-compulsive disorder related brain regions |
ZHANG Hui GUO Suqin |
Department of Child and Adolescent Psychiatry, the Second Affiliated Hospital of Xinxaing Medical University, Henan Province, Xinxiang 453002, China |
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Abstract Obsessive-compulsive disorder (OCD) usually occurs in childhood / adolescence, and its pathogenesis is still unclear. However, with the development of neural imaging, magnetic resonance imaging has been widely used in the study of OCD, and has played an important role in exploring the mechanism of pediatric OCD. Existing studies have suggested that pediatric OCD have abnormalities in the brain regions. The structural abnormalities are mainly located in the frontal lobe, thalamus, temporal lobe, etc., and the functional abnormalities are mainly in the attention network, executive network, etc., indicating that the disease may be related to neurodevelopmental abnormalities. Therefore, this paper reviews the research progress of magnetic resonance imaging in children and adolescents with OCD, providing evidence for the pathogenesis of pediatric OCD.
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[1] Ruscio AM,Stein DJ,Chiu WT,et al. The epidemiology of obsessive-compulsive disorder in the National Comorbidity Survey Replication [J]. Mol Psychiatry,2010,15(1):53-63.
[2] Stewart SE,Geller DA,Jenike M,et al. Long-term outcome of pediatric obsessive-compulsive disorder:a meta-analysis and qualitative review of the literature [J]. Acta Psychiat Scand,2004,110(1):4-13.
[3] Keymer-Gausset A,Alonso-Solís A,Corripio I,et al. Gray and white matter changes and their relation to illness trajectory in first episode psychosis [J]. Eur Neuropsychopharmacol,2018,28(3):392-400.
[4] Liu W,Gan J,Fan J,et al. Associations of cortical thickness,surface area and subcortical volumes with insight in drug-na?觙ve adults with obsessive-compulsive disorder [J]. Neuroimage Clin,2019,24:102037.
[5] Boedhoe PSW,Schmaal L,Abe Y,et al. Cortical Abnormalities Associated With Pediatric and Adult Obsessive-Compulsive Disorder:Findings From the ENIGMA Obsessive-Compulsive Disorder Working Group [J]. Am J Psychiatry,2018,175(5):453-462.
[6] Takagi Y,Sakai Y,Lisi G,et al. A Neural Marker of Obsessive-Compulsive Disorder from Whole-Brain Functional Connectivity [J]. Sci Rep,2017,7(1):7538.
[7] Yun JY,Boedhoe PSW,Vriend C,et al. Brain structural covariance networks in obsessive-compulsive disorder:a graph analysis from the ENIGMA Consortium [J]. Brain,2020,143(2):684-700.
[8] Jayarajan RN,Venkatasubramanian G,Viswanath B,et al. White matter abnormalities in children and adolescents with obsessive-compulsive disorder:a diffusion tensor imaging study [J]. Depress Anxiety,2012,29(9):780-788.
[9] Lázaro L,Calvo A,Ortiz AG,et al. Microstructural brain abnormalities and symptom dimensions in child and adolescent patients with obsessive-compulsive disorder:a diffusion tensor imaging study [J]. Depress Anxiety,2014,31(12):1007-1017.
[10] Liu W,Hua M,Qin J,et al. Disrupted pathways from frontal-parietal cortex to basal ganglia and cerebellum in patients with unmedicated obsessive compulsive disorder as observed by whole-brain resting-state effective connectivity analysis - a small sample pilot study [J]. Brain Imaging Behav,2021,15(3):1344-1354.
[11] Malvaez M,Greenfield VY,Matheos DP,et al. Habits Are Negatively Regulated by Histone Deacetylase 3 in the Dorsal Striatum [J]. Biol Psychiatry,2018,84(5):383-392.
[12] Vaghi MM,Vértes PE,Kitzbichler MG,et al. Specific Frontostriatal Circuits for Impaired Cognitive Flexibility and Goal-Directed Planning in Obsessive-Compulsive Disorder:Evidence From Resting-State Functional Connectivity [J]. Biol Psychiatry,2017,81(8):708-717.
[13] Haynes WIA,Clair AH,Fernandez-Vidal S,et al. Altered anatomical connections of associative and limbic cortico-basal-ganglia circuits in obsessive-compulsive disorder [J]. Eur Psychiatry,2018,51:1-8.
[14] Vattimo EFQ,Barros VB,Requena G,et al. Caudate volume differences among treatment responders,non-responders and controls in children with obsessive-compulsive disorder [J]. Eur Child Adolesc Psychiatry,2019, 28(12):1607-1617.
[15] Zarei M,Mataix-Cols D,Heyman I,et al. Changes in gray matter volume and white matter microstructure in adolescents with obsessive-compulsive disorder [J]. Biol Psychiatry,2011,70(11):1083-1090.
[16] Yang X,Hu X,Tang W,et al. Intrinsic brain abnormalities in drug-naive patients with obsessive-compulsive disorder:A resting-state functional MRI study [J]. J Affect Disord,2019,245:861-868.
[17] Thorsen AL,Hagland P,Radua J,et al. Emotional Processing in Obsessive-Compulsive Disorder:A Systematic Review and Meta-analysis of 25 Functional Neuroimaging Studies [J]. Biol Psychiatry Cogn Neurosci Neuroimaging,2018,3(6):563-571.
[18] Nemoto K. Understanding Voxel-Based Morphometry [J]. Brain Nerve,2017,69(5):505-511.
[19] Rotge JY,Aouizerate B,Amestoy V,et al. The associative and limbic thalamus in the pathophysiology of obsessive-compulsive disorder:an experimental study in the monkey [J]. Transl Psychiatry,2012,2(9):e161.
[20] Melloni M,Urbistondo C,Sede?觡o L,et al. The extended fronto-striatal model of obsessive compulsive disorder:convergence from event-related potentials,neuropsychology and neuroimaging [J]. Front Hum Neurosci,2012,6:259.
[21] Jayarajan RN,Agarwal SM,Viswanath B,et al. A Voxel Based Morphometry Study of Brain Gray Matter Volumes in Juvenile Obsessive Compulsive Disorder [J]. J Can Acad Child Adolesc Psychiatry,2015,24(2):84-91.
[22] Beucke JC,Sepulcre J,Talukdar T,et al. Abnormally high degree connectivity of the orbitofrontal cortex in obsessive-compulsive disorder [J]. JAMA Psychiatry,2013,70(6):619-629.
[23] Gon?觭alves ?魷F,Soares JM,Carvalho S,et al. Patterns of Default Mode Network Deactivation in Obsessive Compulsive Disorder [J]. Sci Rep,2017,7:44468.
[24] Fan J,Zhong M,Gan J,et al. Spontaneous neural activity in the right superior temporal gyrus and left middle temporal gyrus is associated with insight level in obsessive-compulsive disorder [J]. J Affect Disord,2017,207:203-211.
[25] Koprivová J,Horácek J,Tintera J,et al. Medial frontal and dorsal cortical morphometric abnormalities are related to obsessive-compulsive disorder [J]. Neurosci Lett,2009,464(1):62-66.
[26] Shaw P,Sharp W,Sudre G,et al. Subcortical and cortical morphological anomalies as an endophenotype in obsessive-compulsive disorder [J]. Mol Psychiatry,2015,20(2):224-231.
[27] Scott RB,Stoodley CJ,Anslow P,et al. Lateralized cognitive deficits in children following cerebellar lesions [J]. Dev Med Child Neurol,2010,43(10):685-691.
[28] Cabrera B,Romero-Rebollar C,Jiménez-?譧ngeles L,et al. Neuroanatomical features and its usefulness in classification of patients with PANDAS [J]. CNS Spectr,2019,24(5):533-543.
[29] Woolley J,Heyman I,Brammer M,et al. Brain activation in paediatric obsessive compulsive disorder during tasks of inhibitory control [J]. Br J Psychiatry,2008,192(1):25-31.
[30] Norman LJ,Carlisi CO,Christakou A,et al. Neural dysfunction during temporal discounting in paediatric Attention-Deficit/Hyperactivity Disorder and Obsessive-Compulsive Disorder [J]. Psychiatry Res Neuroimaging,2017,269:97-105. |
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