|
|
Effect of microsurgery in the treatment of drug-resistant epilepsy under the monitoring of electrocorticogram |
LI Jialiang MIAO Pengfei YANG Quanxi HUANG Qi LIU Wenxiang SHEN Xianghui |
Department of Neurosurgery, the First People’s Hospital of Shangqiu, Henan Province, Shangqiu 476100, China |
|
|
Abstract Objective To investigate the effect of microsurgery in the treatment of drug-resistant epilepsy under the monitoring of electrocorticogram. Methods Clinical data of 30 patients with drug-resistant epilepsy admitted to the First People’s Hospital of Shangqiu, Henan Province from January 2014 to October 2019 were analyzed. In all patients, the lesions were removed by microsurgical technique under the monitoring of electroencephalogram. Head CT was reviewed on the first day after the operation, to understand the intracranial hemorrhage and cerebral edema, to observe the seizure and complications, and to monitor the vital signs. The postoperative follow-up was from three months to five years, and the results were evaluated by Tan’s classification. Results All the patients were followed up for an average of (2.78±1.46) years. One case of postoperative homohemianopsia occurred, accounting for 6.25% (1/16) of the patients undergoing temporal lobe epilepsy surgery. No surgical death, intracranial infection, intracranial hemorrhage, hemiplegia, aphasia, and other complications occurred. The results were satisfactory in 22 cases, significantly improved in five cases and good in three cases. Conclusion Microsurgical technique under electroencephalogram monitoring is an effective method to treat drug-resistant epilepsy.
|
|
|
|
|
[1] Rugg-Gunn F,Miserocchi A,McEvoy A. Epilepsy surgery [J]. Pract Neurol,2020,20(1):4-14.
[2] Brodie MJ. Pharmacological treatment of drug-resistant epilepsy in adults:a practical guide [J]. Curr Neurol Neurosci Rep,2016,16(9):82.
[3] Fisher RS,Cross JH,French JA,et al. Operational classification of seizure types by the International League Against Epilepsy:Position Paper of the ILAE Commission for Classification and Terminology [J]. Epilepsia,2017,58(4):522-530.
[4] 谭启富,林志国.癫痫外科手册[M].北京:人民卫生出版社,2010:497.
[5] Zack MM,Kobau R. National and state estimates of the numbers of adults and children with active epilepsy——United States,2015 [J]. MMWR Morb Mortal Wkly Rep,2017,66(31):821-825.
[6] 布朗·霍姆斯.临床癫痫手册[M].刘献增等译.北京:人民卫生出版社,2006:1.
[7] Jobst BC,Cascino GD. Resective epilepsy surgery for drug-resistant focal epilepsy:a review [J]. JAMA,2015,313(3):285-293.
[8] Jones AL,Cascino GD. Evidence on use of neuroimaging for surgical treatment of temporal lobe epilepsy:a systematic review [J]. JAMA Neurol,2016,73(4):464-470.
[9] Cendes F,Theodore WH,Brinkmann BH,et al. Neuroimaging of epilepsy [J]. Handb Clin Neurol,2016,136:985-1014.
[10] 刘涛,兰春伟,袁昆雄,等.老年部分性发作癫痫持续状态的临床特征及视频脑电图分析[J].中国医药导报,2019, 16(16):95-99.
[11] 许启锋,刘花琴,谭红愉.24h动态脑电图检查在癫痫患者中的应用[J].中国当代医药,2020,27(25):78-80.
[12] Gregory D,Cascino MD,Benjamin H,et al. Advances in the surgical management of epilepsy drug-resistant focal epilepsy in the adult patient [J]. Neurol Clin,2021,39(1):181-196.
[13] Bonney PA,Boettcher LB,Conner AK,et al. Review of seizure outcomes after surgical resection of dysembryoplastic neuroepithelial tumors [J]. J Neurooncol,2016, 126(1):1-10.
[14] Giulioni M,Marucci G,Pelliccia V,et al. Epilepsy surgery of“low grade epilepsy associated neuroepithelial tumors”:a retrospective nationwide Italian study [J]. Epilepsia,2017,58(11):1832-1841.
[15] 任连坤,吴立文.颅内电极的临床应用和进展[J].中华临床医师杂志:电子版,2012,6(9):2294-2295.
[16] Berg AT,Vickrey BG,Langfitt JT,et al. The multicenter study of epilepsy surgery:recruitment and selection for surgery [J]. Epilepsia,2003,44(11):1425-1433.
[17] Greiner HM,Homn PS,Tenney JR,et al. Preresection intraoperative eleetrocorticography(ECoG)abnormalities predict seizure onset zone and outcome in pediatric epilepsy surgery [J]. Epilepsia,2016,57(4):582-589.
[18] 李晶,杨萍,孙永敏,等.PET-CT联合神经导航在难治性癫痫术中致痫灶定位中的应用[J].中国实用神经疾病杂志,2020,23(6):529-533.
[19] 华刚,谭红平,张立民,等.低级别胶质瘤及混合神经元胶质瘤相关癫痫的手术治疗策略[J].临床神经外科杂志,2019,16(6):465-471.
[20] 徐德辉,谢海涛,伍犹梁,等.脑灰质异位合并巨脑回及海马硬化致药物难治性癫痫1例[J].中国临床神经外科杂志,2019,24(1):64.
[21] 王峰,冯德宁,刘阳,等.以癫痫为主要表现的颞叶海绵状血管瘤手术治疗效果[J].中华医学杂志,2018,98(9):658-661.
[22] 赵瑞,周渊峰,杨皓玮,等.儿童颞叶癫痫的临床特点及手术疗效分析[J].临床小儿外科杂志,2018,17(4):269-273.
[23] 梁明礼,叶敏,张文波,等.症状性颞叶癫痫显微外科手术疗效分析[J].中国医药科学,2019,9(14):183-185, 196.
[24] 冯斌,蔡明,朱红玉,等.皮层脑电图监测颞叶病变合并癫痫的手术治疗[J].脑与神经疾病杂志,2011,19(5):353-355.
[25] 王闻姣,吴漳益.影响手术治疗难治性颞叶癫痫预后的影响因素分析[J].中国现代医生,2020,58(24):42-45.
[26] Engel J Jr,McDermott MP,Wiebe S,et al. Early surgical therapy for drug-resistant temporal lobe epilepsy:a randomized trial [J]. JAMA,2012,307(9):922-930.
[27] Wiebe S,Blume WT,Girvin JP,et al. A randomized,controlled trial of surgery for temporal-lobe epilepsy [J]. N Engl J Med,2001,345(5):311-318.
[28] 杨梅华,安宁,刘仕勇,等.159例颞叶癫痫手术疗效分析[J].立体定向和功能神经外科杂志,2008,21(3):136-139.
[29] Unterberger I,Bauer R,Walser G,et al. Corpus callosam and epilepsies [J]. Seizure,2016,37(1):55-60.
[30] 曹毅,高魏娜,高晋健,等.40例颅脑MRI阴性药物难治性癫痫患者手术疗效研究[J].四川医学,2015,36(10):1043-1046.
[31] 吴柏林,郭燕舞.磁共振阴性药物难治性癫痫的手术治疗[J].实用医学杂志,2016,32(8):1205-1208. |
|
|
|