早发型重度子痫前期患者不同终止妊娠时机、分娩方式对母婴结局的影响

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Abstract Objective To explore the effect of different timing of pregnancy termination and mode of delivery on maternal and infant outcome in patients with early onset severe preeclampsia. Methods The clinical data of 86 patients with early onset severe preeclampsia admitted to Wuxi Eighth People’s Hospital from January 2014 to June 2020 were retrospectively analyzed. According to different timing of pregnancy termination, they were divided into group A (27 cases, timing of pregnancy termination＜32 weeks), group B (31 cases, timing of pregnancy termination was 32-34 weeks), and group C (28 cases, timing of pregnancy termination＞34 weeks); according to the mode of delivery, they were divided into vaginal delivery group (35 cases) and cesarean section group (51 cases). The complications and perinatal outcomes were compared in each groups. Results The onset of gestational age of group B and group C were greater than those of group A, and the onset of gestational age of group C was greater than that of group B, and the differences were statistically significant (P < 0.05). The duration of conservative treatment in group C was shorter than that in group B, and the duration of conservative treatment in group B was longer than that in group A, and the differences were statistically significant (P < 0.05). There was no significant difference in the total incidence of pregnancy complications among three groups (P > 0.05). The rate of perinatal mortality and neonatal asphyxia in group B and group C were lower than those in group A, and Apgar score was higher than that in group A, and the differences were statistically significant (P < 0.05). The birth weight of group C was higher than that of group A and group B, and the birth weight of group B was higher than that of group A, and the differences were statistically significant (P < 0.05). The rate of perinatal mortality, fetal distress and neonatal asphyxia in cesarean section group were lower than those in vaginal delivery group, and Apgar score was higher than that in vaginal delivery group, and the differences were statistically significant (P < 0.05). Conclusion Under the premise of ensuring safety, prolonging the gestational period to over 34 weeks in patients with early-onset severe preeclampsia has a better maternal and infant outcome, and improves the quality of neonatal survival. In addition, cesarean section can effectively reduce the incidence of perinatal mortality and neonatal asphyxia.

Key words： Early onset severe preeclampsia Pregnancy termination Mode of delivery Maternal and infant outcome

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	ZHANG Ke1 YANG Yixin2 ZHANG Bo2

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ZHANG Ke1 YANG Yixin2 ZHANG Bo2. Effect of different timing of pregnancy termination and mode of delivery on maternal and infant outcomes in patients with early onset severe preeclampsia[J]. 中国医药导报, 2021, 18(24): 92-95.

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https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2021/V18/I24/92

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