MicroRNAs在急性心肌梗死诊断及预后中的研究进展

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Abstract Acute myocardial infarction (AMI) is one of the most common cardiovascular emergencies in the world, with high morbidity and mortality. Early and accurate diagnosis can slow down the development of AMI and reduce the mortality. MicroRNAs (miRNAs) are involved in vascular remodeling after myocardial infarction by affecting myocardial cell proliferation, apoptosis and autophagy. More and more studies have confirmed that abnormal expression of miRNAs can be used as biomarkers for diagnosis and prognosis in patients with AMI, which may have important clinical significance for the treatment of AMI patients. This article reviews the recent advances in the therapeutic role of miRNAs in AMI, and summarizes the potential use of miRNAs as biomarkers for the diagnosis and prognosis of AMI.

Key words： Acute myocardial infarction MicroRNA Myocardial remodeling

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	LI Yibo ZHAO Guoan MENG Weizheng WANG Xiulong LI Dongxu LIN Fei

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LI Yibo ZHAO Guoan MENG Weizheng WANG Xiulong LI Dongxu LIN Fei. Research progress of microRNAs in the diagnosis and prognosis of acute myocardial infarction[J]. 中国医药导报, 2021, 18(24): 44-47.

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https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2021/V18/I24/44

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