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Diagnostic efficacy of fully digital molybdenum target X-ray, ultrasound and magnetic resonance imaging in elderly patients with breast tumors |
LIN Jiping TONG Taoran ZHAO Xiping HU Xianjin▲ |
Department of Ultrasound, Tongling People’s Hospital, Anhui Province, Tongling 244000, China |
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Abstract Objective To explore the diagnostic efficiency of fully digital mammography, ultrasound and magnetic resonance imaging in elderly patients with breast tumors. Methods The 101 elderly patients with breast tumors admitted to Tongling People’s Hospital in Anhui Province from January 2016 to September 2020 were selected as the research subjects. All patients received fully digital mammography, ultrasound and magnetic resonance imaging. The imaging data of all patients were retrospectively analyzed. Pathological results as the “gold standard” were used, and the diagnostic efficacy of the three diagnostic methods for malignant breast tumors were compared. Results A total of 101 elderly patients with breast tumors were diagnosed with 34 cases of malignant tumors by pathological examination. There were 28, 19, 26, and 33 malignant tumors detected by fully digital mammography, ultrasound, magnetic resonance imaging and combined diagnosis, respectively. The area under the curve (AUC) of different diagnostic methods for malignant breast tumors was combined diagnosis (0.960), fully digital mammography (0.795), ultrasound (0.669), and magnetic resonance imaging (0.640). The combined diagnosis of AUC was compared with fully digital mammography, ultrasound, and magnetic resonance imaging, and the differences were statistically significant (P < 0.05). The sensitivity, specificity and accuracy of the combined diagnosis of the three were 97.06%, 89.55% and 92.08%, respectively, which were higher than those of various single tests. Conclusion Fully digital mammography and ultrasound can be used as the first choice for early screening of advanced breast cancer in clinical. For patients with suspicious screening results, the results of magnetic resonance imaging can be further clarified, thereby improving the accuracy of their diagnosis.
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[1] 唐帆,曹春莉,曹玉文,等.超声弹性成像技术与乳腺X线摄影对乳腺良恶性肿块的诊断价值[J].实用医学杂志,2019,35(11):142-146.
[2] Aumeeruddy MZ,Mahomoodally MF. Combating breast cancer using combination therapy with 3 phytochemicals:Piperine,sulforaphane,and thymoquinone [J]. Cancer,2019, 125(10):1600-1611.
[3] Garrido-Castro AC,Lin NU,Polyak K. Insights into Molecular Classifications of Triple-Negative Breast Cancer:Improving Patient Selection for Treatment [J]. Cancer Discov,2019,9(2):176-198.
[4] 刘慧宇,王贤明,王金生.全数字化钼靶X线摄影、彩色多普勒超声和磁共振成像对乳腺肿瘤病情诊断的作用[J].中国急救医学,2018,38(z1):258-259.
[5] 李相生,樊红霞,宋云龙,等.术前MRI动态增强扫描可降低早期非肿块型乳腺癌保乳术切缘阳性率[J].中华肿瘤杂志,2017,39(10):768-774.
[6] 程兰兰,刘斌,胡汉金,等.数字乳腺断层摄影与常规影像学检查对乳腺肿块型病变诊断的对比研究[J].临床放射学杂志,2019,350(9):69-73.
[7] 唐晓雯,赵玉年,庄姗,等.DWI-MRI联合X线钼靶对乳腺疾病的诊断价值研究[J].中国临床医学影像杂志,2019, 30(8):548-552.
[8] 吴晓琴,刘晓岭,于志强,等.术前超声造影联合FNAC定位与定性检查在乳腺癌前哨淋巴结活检中的意义[J].中国老年学杂志,2018,38(12):62-65.
[9] Baban CK,Devane L,Geraghty J. Change of paradigm in treating elderly with breast cancer:are we undertreating elderly patients? [J]. Ir J Med Sci,2019,188(2):379-388.
[10] 吴明晓,李晨,陈秀华,等.超声造影评估老年人三阴性乳腺癌新辅助化疗疗效的应用价值[J].中华老年医学杂志,2019,38(7):787-791.
[11] 段淑英,杨学东,孙黎,等.钼靶X线假阴性乳腺癌的MRI特征[J].中国医学影像学杂志,2018,26(9):20-23.
[12] Miglietta F,Griguolo G,Guarneri V,et al. Programmed Cell Death Ligand 1 in Breast Cancer:Technical Aspects,Prognostic Implications,and Predictive Value [J]. Oncologist,2019,24(11):e1055-e1069.
[13] 汤伟,杨孟,高毅,等.数字乳腺断层融合X线摄影术前评估乳腺癌肿块大小的效能对比研究[J].中国癌症杂志,2018,28(11):813-818.
[14] Hartman AL,Sullivan S,Alshora S,et al. Magnetic Resonance Imaging Technologist Breast Subspecialty Program; a Quality Improvement Project Gone Right [J]. Curr Probl Diagn Radiol,2020,49(1):2-6.
[15] 张琦,宋富桂,吕哲昊,等.致密型乳腺对乳腺癌的影响及其补充筛查[J].放射学实践,2020,35(6):806-809.
[16] Vairavan R,Abdullah O,Retnasamy PB,et al. A Brief Review on Breast Carcinoma and Deliberation on Current Non Invasive Imaging Techniques for Detection [J]. Curr Med Imaging Rev,2019,15(2):85-121.
[17] 符川,张建辉,张业雨,等.彩色多普勒超声联合全数字化X线检查对乳腺癌老年患者诊断准确性的影响[J].中国老年学,2016,36(17):4228-4230.
[18] 曾辉,秦杰,秦耿耿,等.全数字化乳腺X线摄影联合乳腺超声对老年乳腺癌的诊断价值[J].广东医学,2016, 37(11):1640-1643.
[19] Kim SH,Kim HH,Moon WK. Automated Breast Ultrasound Screening for Dense Breasts [J]. Korean J Radiol,2020,21(1):15-24.
[20] Pham R,Marshall H,Plecha D. Abbreviated Protocol Breast MRI [J]. AJR Am J Roentgenol,2020,215(3):765-769.
[21] Takuwa H,Tsuji W,Yotsumoto F. Overall survival of elderly patients with breast cancer is not related to breast-cancer specific survival:A single institution experience in Japan [J]. Breast Dis,2018,37(4):177-183.
[22] Partridge SC,Nissan N,Rahbar H,et al. Diffusion-weighted breast MRI:Clinical applications and emerging techniques [J]. J Magn Reson Imaging,2017,45(2):337-355.
[23] Lehman CD,Gatsonis C,Romanoff J,et al. Association of Magnetic Resonance Imaging and a 12-Gene Expression Assay With Breast Ductal Carcinoma In Situ Treatment [J]. JAMA Oncol,2019,5(7):1036-1042.
[24] Xiang W,Rao H,Zhou L. A meta-analysis of contrast-enhanced spectral mammography versus MRI in the diagnosis of breast cancer [J]. Thorac Cancer,2020,11(6):1423-1432.
[25] Richter V,Hatterman V,Preibsch H,et al. Contrast-enhanced spectral mammography in patients with MRI contraindications [J]. Acta Radiol,2018,59(7):798-805. |
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