早期ERCP联合EST治疗急性胆源性胰腺炎伴急性胆管炎的临床效果

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Abstract Objective To study the clinical effect of early endoscopic retrograde cholangiopancreatography (ERCP) combined with endoscopic sphincterotomy (EST) in the treatment of acute biliary pancreatitis (ABP) with acute cholangitis. Methods A total of 90 patients with ABP complicated with acute cholangitis admitted to the Department of Hepatobiliary and Pancreatic Surgery, General Hospital of Anhui Wanbei Coal and Power Group, Anhui Province from June 2018 to June 2020 were selected as the research subjects. According to the random number table method, they were divided into study group and control group, with 45 patients in each group. The control group received conservative treatment, and the study group received early ERCP combined with EST on the basis of the control group. The levels of white blood cells (WBC), serum amylase (SAMY), total bilirubin (TBil), the recovery time of each index, the abdominal pain relief time, the length of postoperative hospital stay, the treatment cost and the incidence of complications were recorded before and 3 d after treatment in both groups. Results Before treatment, there were no significant differences in WBC, SAMY and TBil levels between the two groups (P ＞ 0.05). After treatment, WBC, SAMY and TBil levels in the two groups were lower than before treatment, and the study group was lower than the control group, the differences were statistically significant (P ＜ 0.05). The recovery time of the levels of WBC, SAMY and TBil indexes in the study group was significantly shorter than that in the control group, with statistical significance (P ＜ 0.05). The abdominal pain relief time and the length of postoperative hospital stay in the study group were significantly shorter than those in the control group, but the treatment cost was significantly higher than that in the control group, with statistical significance (P ＜ 0.05). There was no significant difference in the total incidence of complications between the two groups (P ＞ 0.05). Conclusion Early ERCP combined with EST has significant efficacy in the treatment of ABP with acute cholangitis, which can effectively shorten the treatment time. However, compared with the traditional conservative treatment, the treatment cost is relatively higher. Therefore, the appropriate treatment method can be selected according to the actual situation of patients.

Key words： Acute biliary pancreatitis Acute cholangitis Endoscopic retrograde cholangiopancreatography Endoscopic sphincterotomy

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	HAN Su CHEN Xilan XU Mingyou YANG Xianfen

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HAN Su CHEN Xilan XU Mingyou YANG Xianfen. Clinical effect of early ERCP combined with EST in the treatment of acute biliary pancreatitis with acute cholangitis[J]. 中国医药导报, 2021, 18(22): 113-116.

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https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2021/V18/I22/113

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