复方伤痛胶囊联合射频消融术治疗腰椎间盘突出症的效果

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Abstract Objective To observe the effect of Compound Shangtong Capsules combined with radiofrequency ablation in the treatment of lumbar disc herniation (LDH). Methods A total of 124 LDH patients admitted to Youjiang Medical University for Nationalities from September 2018 to April 2019 were selected and they were divided into control group and observation group according to random number table method, with 62 cases in each group. The control group received oral Diclofenac Sodium Sustained-release Tablets after radiofrequency ablation, and the observation group received oral Compound Shangtong Capsules after radiofrequency ablation. The treatment course was ten days. Numerical rating scale (NRS) score, lumbar Oswestry disability index (ODI) score and clinical efficacy were compared between the two groups. The inflammatory factors (interleukin [IL]-1β, IL-6, IL-8, tumor necrosis factor-α [TNF-α]) in serum were determined by enzyme linked immunosorbent assay, and the incidence of adverse reactions was recorded. Results After treatment, NRS score, ODI score, IL-1β, IL-6, IL-8, TNF-α levels in two groups were decreased compared with before treatment, with statistical significance (P ＜ 0.05). There was no significant difference in NRS score, ODI score, IL-1β, IL-6, IL-8 and TNF-α levels between the two groups (P ＞ 0.05). There was no statistical significance in the excellent and good rates between the two groups (P ＞ 0.05). The incidence of adverse reactions in the observation group was lower than that in the control group, and the difference was statistically significant (P ＜ 0.05). Conclusion Compound Shangtong Capsules are safe and effective in the treatment of LDH, which were worthy of clinical promotion.

Key words： Compound Shangtong Capsules Radiofrequency ablation Lumbar disc herniation Pain Inflammation

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	HUANG Jinyi DENG Jun▲ WEI Ke WEN Zhiqian LAN Jian

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HUANG Jinyi DENG Jun▲ WEI Ke WEN Zhiqian LAN Jian. Effect of Compound Shangtong Capsules combined with radiofrequency ablation in the treatment of lumbar disc herniation[J]. 中国医药导报, 2021, 18(21): 88-91.

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https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2021/V18/I21/88

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