维持性血液透析糖尿病肾病患者冠状动脉钙化的危险因素分析

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Abstract Objective To investigate the risk factors of coronary artery calcification (CAC) in patients with maintenance hemodialysis (MHD) diabetic nephropathy. Methods Clinical data of 91 patients with diabetic nephropathy who underwent MHD in Yixing People’s Hospital of Jiangsu Province from January to December 2018 were retrospectively analyzed. The clinical data of the patients were collected and they were divided into the no-CAC group (28 cases) and CAC group (63 cases) according to the coronary artery calcification score (CACs). The risk factors of CAC in patients with MHD diabetic nephropathy were analyzed. Results There were statistically significant differences in age, dialysis age, smoking history, serum calcium, intact parathyoid hormone (iPTH) and pruritus scores between the two groups (P < 0.05). Age >60 years old, smoking history, iPTH >302.71 pg/ml and pruritus score ≥4 points were risk factors for CAC in patients with MHD diabetic nephropathy (OR > 1, P < 0.05). Conclusion Age, smoking history, iPTH and pruritus score are independent risk factors for CAC in patients with MHD diabetic nephropathy. In the course of treatment, clinicians should pay attention to the identification of high-risk patients, early intervention, improve the clinical prognosis of patients, reduce the incidence of cardiovascular disease.

Key words： Diabetic nephropathy Maintenance hemodialysis Coronary artery calcification Risk factors

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	SHAO Li’na LI Ye FAN Wei SONG Kai

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SHAO Li’na LI Ye FAN Wei SONG Kai. Risk factors for coronary artery calcification in patients with maintenance hemodialysis diabetic nephropathy[J]. 中国医药导报, 2021, 18(20): 55-58.

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https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2021/V18/I20/55

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