基于“消渴”探讨葛根治疗糖尿病性硬肿病的可能机制

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Abstract Scleredema diabeticorum is caused by internal hotness, dysfunction of the stomach, spleen and lungs, and hybridization of wind, cold and dampness. Scleredema diabeticorum has the effects of invigorating yin qi and promoting body fluid, and it is an important medicine for the treatment of diabetic thirst and various paralysis. However, there is no systematic study and related reports on the therapeutic effect of Puerariae Lobatae Radix on scleredema diabeticorum. Through clinical observation and research on ancient and modern Chinese and foreign literature, the author believes that the effective components of Puerariae Lobatae Radix have the effects of regulating blood glucose, inhibiting inflammation and anti-fibrosis, which can have obvious therapeutic effects on scleredema diabeticorum. In this paper, from the perspective of “consumptive thirst”, based on the theory of traditional Chinese medicine, combined with the modern pharmacological research results of Puerariae Lobatae Radix, the possible mechanism of Puerariae Lobatae Radix in the treatment of scleredema diabeticorum is elaborated in detail, in order to provide new ideas and methods for the clinical diagnosis and treatment of scleredema diabeticorum.

Key words： Puerariae Lobatae Radix Consumptive thirst Scleredema diabeticorum Blood glucose Inflammation

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	ZHANG Shuyuan1 DONG Xiuhui1 ZHANG Qinyuan2 YAN Peizheng2 CHANG Xing3 ZHANG Xiao1

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ZHANG Shuyuan1 DONG Xiuhui1 ZHANG Qinyuan2 YAN Peizheng2 CHANG Xing3 ZHANG Xiao1. Discussion on possible mechanism of Puerariae Lobatae Radix in the treatment of scleredema diabeticorum based on “consumptive thirst”[J]. 中国医药导报, 2021, 18(19): 122-125,146.

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https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2021/V18/I19/122

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