13例干燥综合征合并胰腺炎患者临床特征分析

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Abstract Objective To summarize and analyze the clinical characteristics of patients with Sj?觟gren syndrome (SS) complicated with pancreatitis in China based on literatures. Methods The literatures on SS complicated with pancreatitis in CNKI, Wanfang Data, VIP and CBM were searched manually and by computer. The time limit for retrieval was from the inception to August 2020. The search terms were “Sj?觟gren syndrome” AND “pancreatitis”. The literatures that met the inclusion and exclusion criteria were selected, the information was extracted, and the clinical characteristics were analyzed. Results Eight literatures were included, and a total of 13 cases were reported, all of which were female. Its main clinical characteristics of a dry mouth / eye (13 cases), tooth loss/caries (four cases), renal tubular acidosis (four cases), joint pain (three cases), swollen glands (three cases), skin rash (two cases), Raynaud phenomenon (two cases), oral ulcer (one case), dry nasal cavity (one case) and vaginal discharge reduction (one case). The main clinical characteristics of pancreatitis in Sj?觟gren syndrome were abdominal pain (11 cases), nausea / vomiting (seven cases), abdominal distension (five cases), fever (two cases) and no obvious clinical symptoms (one case). Nine patients were treated with glucocorticoid combined with/without immunosuppressant therapy, of which one case died of septic shock and eight cases improved. Conclusion As the clinical characteristics of SS complicated with pancreatitis are varied, the diagnosis and treatment of SS complicated with pancreatitis are highly dependent on the personal experience of physicians, and there is no unified standard, nor recognized effective diagnosis and treatment measures.

Key words： Sj?觟gren syndrome Pancreatitis Clinical characteristics Literatures analysis

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	LI Hongsong1 ZHU Guangzhao2 LYU Liu3 WANG Hailong3

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LI Hongsong1 ZHU Guangzhao2 LYU Liu3 WANG Hailong3. Clinical characteristics of 13 patients with Sj?觟gren syndrome complicated with pancreatitis[J]. 中国医药导报, 2021, 18(19): 95-97.

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https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2021/V18/I19/95

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