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| Effect of integrated traditional Chinese and Western medicine on early threatened abortion and pregnancy outcome |
| CAO Kun1 YAN Tingqing2 |
1.Department of Obstetrics and Gynecology, Liaocheng Traditional Chinese Medicine Hospital, Shandong Province, Liaocheng 252000, China;
2.Intensive Care Unit, Liaocheng Traditional Chinese Medicine Hospital, Shandong Province, Liaocheng 252000, China |
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Abstract Objective To investigate the effect of integrated traditional Chinese and Western medicine on early threatened abortion and the effect of pregnancy outcome. Methods A total of 118 patients with threatened abortion treated in Liaocheng Traditional Chinese Medicine Hospital from January 2018 to January 2020 were selected as study objects. According to the random number table method, they were divided into control group and observation group, with 59 cases in each group. Control group was treated with conventional Western medicine, and observation group was treated with Jiawei Shoutai Pills on the basis of control group, and the treatment lasted for 2 courses. The clinical curative effect, traditional Chinese medicine syndrome score, serum hormone level, complication and pregnancy outcome were compared between two groups. Results The total effective rate of observation group was higher than that of control group, and the difference was statistically significant (P < 0.05). Before treatment, there was no significant difference in traditional Chinese medicine syndrome score between two groups (P ＞ 0.05). After treatment, traditional Chinese medicine syndrome scores of two groups were lower than those before treatment, and observation group was lower than control group, and the differences were statistically significant (P < 0.05). Before treatment, there were no significant differences in serum levels of human chorionic gonadotrophin-β subunit (β-HCG), estradiol (E2), and progesterone (P) between two groups (P > 0.05). After treatment, the levels of β-HCG, E2, and P in two groups were higher than those before treatment, and observation group was higher than control group, and the differences were statistically significant (P < 0.05). There was no significant difference in the total incidence of complications between two groups (P > 0.05). The birth rate, newborn weight and Apgar score of observation group were higher than those of control group, and the neonatal asphyxia rate and premature birth rate were lower than those of control group, and the differences were statistically significant (P < 0.05). Conclusion The clinical effect of the treatment of early threatened abortion patients with integrated traditional Chinese and Western medicine is significant, can effectively alleviate the clinical symptoms, regulate the serum hormone level, while not increasing the incidence of complications, to obtain a better pregnancy outcome.
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[1] 杨宏慧.中西医结合治疗先兆流产及复发性流产临床疗效观察[J].饮食保健，2020，7（5）：128-129.
[2] 丁琅娟，程芙蓉.中西医结合对先兆流产早期患者的疗效及妊娠结局的影响分析[J].中华中医药学刊，2017， 28（5）：1342-1344.
[3] 康岩芳，王翠红.中西医结合治疗先兆流产疗效观察[J].山西中医，2018，34（5）：29-32.
[4] 王芬，田丽颖，顿巨燕.自拟固肾育胎方加减内服结合穴位贴敷治疗肾虚型早期先兆流产25例[J].安徽中医药大学学报，2020，39（4）：34-37.
[5] 谢幸，孔北华，段涛.妇产科学[M].9版.北京：人民卫生出版社，2018.
[6] 刘敏如.中医妇产科学[M].2版.北京：人民卫生出版社，2011.
[7] 郑筱英.中药新药临床研究指导原则[M].北京：人民卫生出版社，2002：79-83.
[8] 姚乃礼.中医症状鉴别诊断学（第二版）[M].北京：人民卫生出版社，2004：89-90.
[9] 韩玉清.中西医结合治疗肾虚型先兆流产44例[J].河南中医，2017，37（1）：128-130.
[10] 何洁丽.寿胎异功散联合黄体酮治疗肾虚血瘀型早期先兆流产疗效观察[J].现代中西医结合杂志，2017，26（14）：1568-1570.
[11] 刘斌，曹文文.脐动脉血气分析及Apgar评分在新生儿窒息评估中的临床应用价值[J].检验医学与临床，2017， 14（13）：1964-1965.
[12] 曹卫平，师伟，李霞，等.加味寿胎丸联合黄体酮调节NKG2D、NKG2A表达治疗肾虚型URSA作用机制研究[J].南京中医药大学学报，2017，33（5）：488-492.
[13] 曾薇薇，周华，陆齐天，等.补肾活血方联合地屈孕酮片治疗先兆流产合并宫腔积血的临床观察[J].上海中西医药大学学报，2020，34（3）：26-30.
[14] 杨洋，吴雨倩.黄体酮在先兆流产中的应用价值分析[J].检验医学与临床，2017，14（3）：381-382.
[15] 赵金青，陈玉荣.滋肾育胎丸联合黄体酮对高龄二胎先兆流产孕妇血清性激素及妊娠结局的影响[J].陕西中医，2017，38（12）：1695-1696.
[16] 李红霞，宋淑红，李姬梅.黄体酮治疗先兆流产患者的临床效果及对妊娠结局的影响[J].医疗装备，2018，31（22）：87-88.
[17] 张金凤，刘阿梅.肝素钠和低剂量黄体酮对先兆流产的疗效分析[J].中国医药科学，2020，10（22）：92-94，116.
[18] 徐萍，赵艳，吴嫣，等.维生素E联合固肾安胎丸对早期先兆流产患者的血清孕酮、β合固肾安、同型半胱氨酸及CA125水平的影响[J].贵州医药，2019，43（9）：1437-1438.
[19] 凌爱华，赵维英.黄体酮联合加味寿胎丸治疗肾虚型早期先兆流产及对炎症因子影响[J].中国计划生育学杂志，2020，28（1）：98-101.
[20] 吴彦佳，符杨浠，蔡燕.紫河车联合寿胎丸加味治疗冷冻胚胎移植术后雌激素低下先兆流产疗效观察[J].现代中西医结合杂志，2020，29（5）：538-541.
[21] 范倩倩，姚丽艳.早期先兆流产患者宫腔积液与下生殖道感染的关系探究[J].中国医药导刊，2019，21（4）：226-228.
[22] 刘新娟，王静，黎东梅，等.孕早期先兆流产危险因素的Logistic回归分析[J].中国计划生育和妇产科，2019，11（3）：45-48.
[23] 余锴，吴芬，周兴.中西医结合治疗症状不典型早期输卵管妊娠临床效果[J].中华中医药学刊，2019，37（7）：1759-1760.
[24] 侯秀红，胡晓梅.补肾健脾方联合地屈孕酮对早期先兆流产的疗效及妊娠结局的影响[J].海南医学，2020，31（2）：211-213.
[25] 彭皇青，边庆华，黄津伶.白及三七散治疗先兆流产中阴道出血临床疗效观察[J].中国现代医生，2020，58（4）：153-156.
[26] 李燕，李晓兰，马俊旗.不同黄体支持法对早期先兆流产及其妊娠结局影响[J].中国计划生育学杂志，2020， 28（1）：44-47. |
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