单侧PVP术对OVCF术后椎体高度恢复及疼痛程度的效果研究

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Abstract Objective To investigate the recovery of vertebral height and the degree of pain after unilateral percutaneous vertebroplasty (PVP) for osteoporotic vertebral compression fracture (OVCF). Methods A total of 84 patients with thoracolumbar single vertebral body OVCF who received PVP treatment in Taizhou Second People’s Hospital, Jiangsu Province from September 2016 to September 2019 were selected. According to the surgical approach, they were divided into unilateral group and bilateral group, including 48 cases in unilateral group and 36 cases in bilateral group. The surgical time, surgical fluoroscopy times and the amount of bone cement injection were compared between the two groups. The changes of visual analogue score (VAS), Oswestry disability index (ODI), vertebral height and Cobb angle were compared between the two groups before and three days after surgery and one year after surgery. Results The times of surgical X-ray fluoroscopy in unilateral group was less than that in bilateral group, and the amount of bone cement injection was lower than that in bilateral group, with statistical significance (all P ＜ 0.05). There were statistically significant differences in VAS and ODI scores between the two groups before and three days after surgery, and one year after surgery, as well as at time points (P ＜ 0.05). Further pairwise comparison showed that VAS and ODI scores at three days and one year after surgery were lower than those before surgery, and one year after surgery were lower than those at three days after surgery, with statistical significance (all P ＜ 0.05). VAS and ODI scores of the unilateral group were lower than those of the bilateral group at the same time point, and the differences were statistically significant (all P ＜ 0.05). There were statistically significant differences in the time point comparison and interaction of vertebral height, Cobb angle between the two groups before and three days and one year after surgery (P ＜ 0.05). Further pairwise comparison: the vertebral height at three days and one year after surgery in both groups was higher than before surgery, Cobb angle was lower than before surgery, and the vertebral height at one year after surgery was lower than three days after surgery, Cobb angle was greater than three days after surgery, the differences were statistically significant (all P ＜ 0.05). Conclusion Both unilateral and bilateral PVP were used in the treatment of OVCF, and the unilateral approach was more advantageous than the bilateral approach in terms of surgry time and number of X-ray fluoroscopy.

Key words： Osteoporotic vertebral compression fracture Percutaneous vertebroplasty Bone cement Clinical efficacy

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	CUI Zhiyuan1 MAO Zhaohu2 LIU Yulin1 WANG Guoxi1

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CUI Zhiyuan1 MAO Zhaohu2 LIU Yulin1 WANG Guoxi1. Effect of unilateral PVP on vertebral height recovery and the degree of pain score after surgery in patients with OVCF[J]. 中国医药导报, 2021, 18(18): 92-95.

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https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2021/V18/I18/92

[1] 范勋奇，石磊.骨质疏松症相关研究进展[J].广东化工，2020，47（2）：63-64，76.
[2] Cui L，Chen L，Xia W，et al. Vertebral fracture in postmenopausal Chinese women a population-based study [J]. Osteoporos Int，2017，28（9）：2583-2590.
[3] 崔利宾，唐本强，王彦辉，等.年龄≥80岁骨质疏松性椎体压缩骨折患者经皮椎体成形术骨水泥渗漏的危险因素分析[J].中国脊柱脊髓杂志，2020，30（6）：530-538.
[4] Zhang L，Wang Q，Wang L，et al. Bone cement distribution in the vertebral body affects chances of recompression after percutaneous vertebroplasty treatment in elderly patients with osteoporotic vertebral compression fractures [J]. Clin Interv Aging，2017，12：431-436.
[5] 徐龙，辛健.PVP、PKP、囊袋治疗新鲜骨质疏松性椎体压缩骨折的临床分析[J].中国矫形外科杂志，2019，27（19）：1812-1815.
[6] 刘祥飞，何金国，蒋钰钢，等.单侧与双侧入路椎体成形术治疗老年骨质疏松性椎体压缩骨折的有限元分析及临床应用[J].医用生物力学，2018，33（3）：218-223.
[7] Heller GZ，Manuguerra M，Chow R. How to analyze the Visual Analogue Scale：Myths，truths and clinical relevance [J]. Scand J Pain，2016，13：67-75.
[8] Fairbank JC，Pynsent PB. The Oswestry Disability Index [J]. Spine（Phila Pa 1976），2000，25（22）：2940-2952.
[9] 吴溢峰，钟姣红，吴焯鹏，等.3种不同入路经皮椎体成形术治疗胸腰段椎体压缩性骨折的疗效比较[J].中国微创外科杂志，2018，18（7）：611-615.
[10] 金掌，张立岩，叶亚云，等.PVP对老年骨质疏松性胸腰椎骨折患者的治疗效果及对骨密度、骨钙素的影响[J].中国医药导报，2019，16（36）：89-91，103.
[11] 谢辉，陈浩鹏，王本杰，等.骨水泥弥散分布类型对不同部位骨质疏松性椎体压缩骨折治疗效果的影响[J].中国组织工程研究，2020，24（28）：4505-4510.
[12] Chang WL，Zhang XY，Jiao N，et al. Unilateral versus bilateral percutaneous kyphoplasty for osteoporotic vertebral compression fractures：A meta-analysis [J]. Medicine（Baltimore），2017，96（17）：e6738.
[13] Zhang ZF，Yang JL，Jiang HC，et al. An updated comparison of high-and low-viscosity cement vertebroplasty in the treatment of osteoporotic thoracolumbar vertebral compression fractures：A retrospective cohort study [J]. Int J Surg，2017，43：126-130.
[14] 黄豪杰，邹伟民，庞祖才，等.单侧穿刺经皮椎体成形术治疗多节段骨质疏松压缩性骨折疗效观察[J].广东医学，2019，40（21）：3055-3058.
[15] 刘欢，费昊东，陈晓钢，等.单、双侧椎弓根入路PVP治疗骨质疏松性椎体压缩骨折比较[J].南京医科大学学报：自然科学版，2019，39（1）：99-103.
[16] Cheng Y，Liu Y. Percutaneous curved vertebroplasty in the treatment of thoracolumbar osteoporotic vertebral compression fractures [J]. J Int Med Res，2019，47（6）：2424-2433.
[17] 罗同青，胡朝晖，谢湘涛.单侧椎弓根旁入路经皮椎体成形术治疗重度椎体压缩骨折42例[J].中国微创外科杂志，2020，20（2）：133-137.
[18] 刘玉刚，王炳辉，龙游，等.经横突上缘椎弓根外侧入路单侧穿刺经皮椎体成形术治疗上腰椎骨质疏松性椎体压缩骨折[J].中华创伤杂志，2018，34（4）：312-318.
[19] Otto LK，Davidson S. Radiation exposure of certified registered nurse anesthetists during ureteroscopy procedures using fluoroscopy [J]. AANA J，1999，67（1）：53-58．
[20] Boerma M，Sridharan V，Mao XW，et al. Effects of ionizing radiation on the heart [J]. Mutat Res，2016，770（Pt B）：319-327.
[21] Hladik D，Tapio S. Effects of ionizing radiation on the mammalian brain [J]. Mutat Res，2016，770（Pt B）：219-230.
[22] Keil AP，Richardson DB. Quantifying Cancer Risk from Radiation [J]. Risk Anal，2018，38（7）：1474-1489.
[23] Holtgrewe M，Knaus A，Hildebrand G，et al. Multisite de novo mutations in human offspring after paternal exposure to ionizing radiation [J]. Sci Rep，2018，8（1）：14611.
[24] Sreetharan S，Thome C，Tharmalingam S，et al. Ionizing Radiation Exposure During Pregnancy：Effects on Postnatal Development and Life [J]. Radiat Res，2017，187（6）：647-658.
[25] Buchbinder R，Johnston RV，Rischin KJ，et al. Percutaneous vertebroplasty for osteoporotic vertebral compression fracture [J]. Cochrane Database Syst Rev，2018，4（4）：CD006349.
[26] 张志伟，李利，黄兹谕，等.单、双侧椎弓根入路及单侧椎弓根外入路椎体成形治疗胸腰段椎体压缩性骨折：骨水泥灌注量与渗漏率[J].中国组织工程研究，2020， 24（9）：1353-1358.
[27] Chen YC，Zhang L，Li EN，et al. Unilateral versus bilateral percutaneous vertebroplasty for osteoporotic vertebral compression fractures in elderly patients：A meta-analysis [J]. Medicine（Baltimore），2019，98（8）：e14317.