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Research progress of exosomes in breast cancer |
XU Jiahan YAO Yongzhong▲ |
Drum Tower Clinical Medical College of Nanjing Medical University, Jiangsu Province, Nanjing 210000, China |
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Abstract Breast cancer cells leave the primary tissue and enter the circulatory system, along the circulatory system to reach the target organs, and eventually form distal metastasis and recurrence of breast cancer, which is the main cause of death of breast cancer patients. Exosomes are small lipid bilaterals released by pluripotent cells, which regulate complex cellular pathways and are involved in all stages of breast cancer from the onset to the spread of metastasis. Studies have shown that exosomes are closely related to breast cancer metastasis, which can promote tumor angiogenesis, help tumor escape the monitoring of the immune system and inhibit immune cells. In this review, we will discuss the role of exosomes in the occurrence and development of breast cancer from the structure of exosomes, and reveal whether exosomes can provide new prospects for the early diagnosis and molecular targeted therapy of breast cancer.
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