缓冲系数对恶性大脑中动脉梗死的预测价值

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Abstract Objective To investigate the predictive value of buffer coefficient in malignant middle cerebral artery infarction (MMI). Methods Clinical data of 131 patients with internal carotid or middle cerebral artery infarction treated to Yongchuan Hospital Affiliated to Chongqing Medical University from January 2017 to August 2020 were retrospectively analyzed. According to whether they had progressed of MMI, the patients were divided into malignant group (53 cases) and non-malignant group (78 cases). The clinical and imaging data of two groups were analyzed. Results Cerebral infarction volume and buffer coefficient in malignant group were larger than those in non-malignant group， while buffer volume was smaller than that in non-malignant group, and the differences were statistically significant（P < 0.05). Cerebral infarction volume and buffer coefficient were risk factors for MMI (OR ＞ 1，P ＜ 0.05), while buffer volume was a protective factor (OR ＜ 1，P ＜ 0.05). The area under curve predicted by buffer coefficient was 0.965, the cut-off value was 2.25, the sensitivity was 87%, and the specificity was 95%. Conclusion Buffer coefficient is better than the cerebral infarction volume or buffer volume to predict the occurrence of MMI, which has certain reference value for the judgment of the condition of middle cerebral artery infarction patients and the choice of treatment plan.

Key words： Cerebral infarction volume Buffer volume Buffer coefficient Malignant middle cerebral artery infarction Predictive value

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	Articles by authors
	WU Lin1
	2 LIU Qingjun1
	2 ZHAO Libo1
	2 TAN Qing1
	2 WEI Jing1
	2 ZHAO Rui1
	2 ZHOU Zhenhua3 LI Xiaobo4

Cite this article:

WU Lin1,2 LIU Qingjun1,2 ZHAO Libo1, et al. Predictive value of buffer coefficient in malignant middle cerebral artery infarction[J]. 中国医药导报, 2021, 18(16): 142-145.

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https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2021/V18/I16/142

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