呼吸科住院患者肺血栓栓塞症延迟诊断的危险因素分析

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Abstract Objective To explore the risk factors of diagnostic delay of pulmonary thromboembolism （PTE） in hospitalized patients at department of respiratory medicine. Methods Clinical data of 98 inpatients with PTE initially diagnosed in the Department of Respiratory Medicine, Beijing Tongren Hospital from December 2011 to December 2019 were collected, and they were divided into delayed diagnosis group (39 cases) and non-delayed diagnosis group (59 cases) according to the median time of PTE diagnosis. The difference of clinical data between the two groups was analyzed, and the risk factors of delayed PTE diagnosis were analyzed by logistic regression. Results The rates of basic pulmonary disease, chronic obstructive pulmonary disease (COPD) and asthma in the delayed diagnosis group were higher than those in the non-delayed diagnosis group, and the differences were all statistically significant (all P ＜ 0.05). The proportion of patients with surgical history in the last one month was lower than that in the non-delayed diagnosis group, and the difference was statistically significant (P ＜ 0.05). The incidence of hemoptysis, syncopal and lower limb edema, D-dimer value, simplified wells score and revised Geneva score in the delayed diagnosis group were lower than those in the non-delayed diagnosis group, with statistical significance (all P ＜ 0.05). The incidence of dyspnea and fever were higher than that in the non-delayed diagnosis group, and the differences were all statistically significant (all P ＜ 0.05). Pulmonary underlying disease (OR = 13.566, 95%CI: 2.410, 76.373) and COPD (OR = 7.030, 95%CI: 1.265, 39.065) were risk factors for delayed diagnosis of PTE (P < 0.05). Conclusion There is a high prevalence in diagnostic delay of PTE in hospitalized patients at department of respiratory medicine. COPD is independently and significantly related to the diagnostic delay of PTE.

Key words： Department of respiratory medicine Pulmonary thromboembolism Diagnosis delay Risk factors

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	LI Ran LIU Xiaofang▲ SHENG Haiyan BAI Peng

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LI Ran LIU Xiaofang▲ SHENG Haiyan BAI Peng. Risk factors of diagnostic delay of pulmonary thromboembolism in hospitalized patients at department of respiratory medicine[J]. 中国医药导报, 2021, 18(16): 91-94.

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https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2021/V18/I16/91

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