基于CiteSpace软件的国内线粒体生物合成研究的文献计量及可视化分析

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Abstract Objective To explore the current situation, hotspots and trends of mitochondrial biogenesis in recent 20 years in China based on bibliometrics. Methods The literatures on mitochondrial biogenesis published from January 2000 to June 2020 in China National Knowledge Internet were searched. CiteSpace was used to conduct co-occurrence analysis with authors, institutions and keywords as nodes, cluster analysis, time evolution analysis and burst analysis of keywords. Corresponding visualization maps were drawn and analyzed. Results There were 168 related literatures. State Key Laboratory of Silkworm Genome Biology in Southwest University and College of Food Science in Southwest University published the most papers. Ding Xiaowen and Ning Junli published the most papers, but they were lack of cooperation. Domestic research focused on mitochondrial biogenesis signaling pathway, the interaction between mitochondrial biogenesis and oxidative stress, mitochondrial autophagy, and mitochondrial apoptosis, as well as the epigenetic modification of proteins related to mitochondrial biogenesis. Conclusion CiteSpace is used to analyze research on mitochondrial biogenesis, which shows the research situation of mitochondrial biogenesis in the recent 20 years, forming a general understanding of research hotspots and trends, providing reference for the research direction.

Key words： CiteSpace Mitochondrial biogenesis Bibliometrics Visualization analysis

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	WANG Ru1
	2 WANG Chenglong1
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WANG Ru1,2 WANG Chenglong1,2. Bibliometrics and visualization analysis of the domestic research of mitochondrial biogenesis based on CiteSpace software[J]. 中国医药导报, 2021, 18(15): 27-31.

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https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2021/V18/I15/27

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