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Analysis of efficacy and safety of laparoscopic treatment of acute pancreatitis by cholecystolithiasis at different operative times |
XU Ziheng SUN Lei HU Wei |
Department of Hepatobiliary Surgery, the First People’s Hospital of Lianyungang, Jiangsu Province, Lianyungang 222000, China |
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Abstract Objective To investigate the efficacy and safety of laparoscopic treatment of acute pancreatitis (AP) caused by cholecystolithiasis at different operative times. Methods A total of 92 AP caused by cholecystolithiasis patients admitted to the First People’s Hospital of Lianyungang from March 2018 to February 2020 were retrospectively analyzed. According to the time of LC treatment, they were divided into two groups, with 46 cases in each group. Among them, 46 patients who underwent LC treatment within 48 hours after admission (recorded as early stage) were classified as group A, and 46 patients who received LC treatment after admission and confirmed that they firstly received drug treatment and waited for 8 to 12 weeks after their condition was stable (recorded as elective) as group B. The related rehabilitation indicators, biochemical indicators, safety and recurrence were compared between the two groups. Results There were no statistically significant differences in operation time and intraoperative blood loss between the two groups (P > 0.05). The postoperative hospital stay in group A was shorter than group B, the difference was statistically significant (P < 0.05). There was no statistically significant difference in the incidence of wound infection, fever, bile leakage and total incidence of postoperative complications between the two groups (P > 0.05). There was no statistically significant difference in the recurrence rate between the two groups (P > 0.05). Conclusion LC treatment for AP patients caused by gallbladder stones within 48 hours after admission to the hospital can effectively shorten the length of postoperative hospital stay. The effect of early LC treatment is equivalent to that of elective LC treatment, and it does not aggravate the liver damage of the patient, and the safety is good.
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