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| A network Meta-analysis of the treatments for endometriosis after laparoscopy |
| ZHANG Wen DU Hao ZU Li YUAN Yuan▲ LI Ning |
| Department of Gynecology， Shenzhen Baoan Zhong Hospital Group， Guangdong Province， Shenzhen 518000， China |
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Abstract Objective To systematically evaluate the clinical efficacy of different treatment methods for endometriosis after laparoscopic surgery. Methods RCTs about endometriosis after laparoscopic surgery from 2007 to 2017 nearly ten years were searched in the database of PubMed， CNKI， CBM， VIP and Wanfang. Eligible RCTs were included and the quality of RCTs were evaluated. The data were extracted and the clinical efficacy of after laparoscopic surgery was Meta analyzed by Stata 14.0 and RevMan 5.3 software. And according to the effective rate of treatment， recurrence rate and pregnancy rate， the network Meta sequencing was ranked. Results A total of 13 RCTs were included in， including 1263 patients with endometriosis. The effective rate of laparoscopy combined with Chinese and Western medicine was higher than that of traditional Chinese medicine therapy and Western medicine therapy， the differences were statistically significant （P < 0.05）. There was no significant difference in the effective rate between simple western medicine and traditional Chinese medicine （P > 0.05）. According to the treatment efficiency， recurrence rate and pregnancy rate ranking order was the combination of Chinese and western， traditional Chinese medicine， western medicine and placebo. Conclusion The clinical curative effect of combined therapy of Chinese and Western in patients with endometriosis after the uterus is most prominent， can effectively improve the treatment efficiency of patients with endometriosis， reduce the recurrence rate and infertility rate. But there may be some selective bias to be included in the study， also need to provide more accurate basis to more high quality RCT.
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