|
|
Analysis on medication rules of traditional Chinese medicine in treating diabetic neurogenic bladder based on data mining |
LIU Zhaowen YAO Yu YU Huilan MA Ru SONG Shuqi |
Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China |
|
|
Abstract Objective To analyze the medication rules of traditional Chinese medicine in treating diabetic neurogenic bladder based on data mining. Methods All relevant prescriptions were searched on CNKI, Wanfang, VIP, SinoMed from the databases establishment to March 2020, those met the criteria were transferred to the traditional Chinese medicine inheritance support platform (V2.5). The frequency of drug use, four qi and five flavor, meridian tropism were statistically analyzed. Results A total of 226 prescriptions were screened out. The tastes of the medicine were mainly sweet, bitter and pungent, and the properties of the medicine were mostly warm and cold, followed by mild. Kidney and bladder was the first in zang and fu about meridian tropism respectively. Milkvetch root, Indian bread and Oriental waterplantain rhizome were the most frequently used. Five new prescriptions were obtained by association rules and cluster analysis. Conclusion This disease is located in the bladder, and is closely related to the kidney. The treatment should focus on the recovery of bladder gasification. The core of the prescriptions is Jingui Shenqi Pills or Wuling Powder.
|
|
|
|
|
[1] 李显筑,郭力,王丹,等.糖尿病神经源性膀胱中医诊疗标准[J].世界中西医结合杂志,2011,6(4):365-368.
[2] Xuke H,Yang G,Shengju W,et al. Effect of electroacupuncture on diabetic neurogenic bladder:a randomized controlled trial protocol [J]. Medicine,2020,99(17):19843.
[3] Powell CR. Is the diabetic bladder a neurogenic bladder? Evidence from the literature [J]. Curr Bladder Dysfunct Rep,2014,9(4):261-267.
[4] 杨楠,肖艳.中西医治疗糖尿病神经源性膀胱的研究进展[J].新疆中医药,2018,36(5):138-140.
[5] 王彩娣,谢君成,曾纪斌.茯苓四逆汤治疗肾阳亏虚型糖尿病神经源性膀胱疗效研究[J].广州中医药大学学报,2020,37(8):1450-1455.
[6] 董铮,曾永保,梅志刚,等.中西医结合治疗糖尿病膀胱的Meta分析[J].山东医药,2011,51(40):77-79.
[7] 杨福双,王中天,孙丽平.基于中医传承辅助系统分析中医药治疗儿童哮喘发作期的用药规律[J].中国中医基础医学杂志,2019,25(8):1078-1081.
[8] 孙颖浩.吴阶平泌尿外科学[M].北京:人民卫生出版社,2019:1246-1247.
[9] 国家药典委员会.中华人民共和国药典[S].一部.北京:中国医药科技出版社,2020:1902.
[10] 钟赣生.中药学[M].北京:中国中医药出版社,2016:482.
[11] 刘括,孙殿钦,廖星,等.随机对照试验偏倚风险评估工具2.0修订版解读[J].中国循证心血管医学杂志,2019, 11(3):284-291.
[12] 卢朋,李健,唐仕欢,等.中医传承辅助系统软件开发与应用[J].中国实验方剂学杂志,2012,18(9):1-4.
[13] 仝小林.糖尿病中医药临床循证实践指南(2016版)[M].北京:科学出版社,2016:234-239.
[14] 王好杰,徐海娥,张洁.鹿茸方治疗糖尿病神经源性膀胱随机平行对照研究[J].实用中医内科杂志,2020,34(7):122-125.
[15] 孙硕,张莎莎,刘红亮,等.从五脏论治癃闭[J].中医药临床杂志,2019,31(2):264-266.
[16] 刘爽,王爱成,刘春燕,等.从五脏辨治癃闭探析[J].江苏中医药,2020,52(10):7-9.
[17] 江铭倩.周国英“从脾论治”糖尿病经验总结[J].江西中医药,2020,51(10):33-36.
[18] 刘敏,兰琴.糖尿病神经源性膀胱治验[J].河南中医,2006,26(5):74-75.
[19] 何军.基于肾气丸证探讨五苓散证之“小便不利”[J].中医学报,2018,33(6):1033-1035.
[20] 苏云婷,唐红.唐红治疗糖尿病神经源性膀胱经验拾零[J].中医文献杂志,2015,33(3):35-37.
[21] 叶琴,杨洋,周雅琴,等.中药甘味成分的研究进展[J].湖南中医杂志,2015,31(11):205-207.
[22] 杨红,杨彩虹,朱晓东,等.中西结合探析甘味中药在糖尿病中的应用[J].光明中医,2014,29(12):2550-2551.
[23] 郭永胜,黄书婷,李良松.中药四气理论的起源与形成探析[J].中医杂志,2020,61(16):1405-1409.
[24] 宋亚刚,苗明三.平性药性味内涵探讨[J].时珍国医国药,2018,29(12):2981-2984.
[25] 张达,武娜,孙文亮,等.从中医理论探讨糖尿病神经源性膀胱的治疗[J].中医药临床杂志,2019,31(11):2000-2003. |
|
|
|